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361. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd4-final-protocol.pdf
     October 01, 2022 - Hand Searching: Reference lists of relevant, recent, high-quality systematic reviews or meta- analysis … Analysis type of primary PTSD outcome measure (ITT, completer) d. … Statistical analysis method for primary PTSD outcome e. … 2.6) Was an appropriate analysis used to estimate the effect of assignment to intervention? … that was finalized before unblinded outcome data were available for analysis?

362. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
     January 01, 2021 - Hand Searching: Reference lists of relevant, recent, high-quality systematic reviews or meta- analysis … Analysis type of primary PTSD outcome measure (ITT, completer) d. … Statistical analysis method for primary PTSD outcome e. … 2.6) Was an appropriate analysis used to estimate the effect of assignment to intervention? … that was finalized before unblinded outcome data were available for analysis?

363. Effect-Dietary-Digestible (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
     January 01, 2021 - one year and puberty are likely sparse.15 Purpose of the Review This systematic review and meta-analysis … We will use relevant systematic reviews and meta-analysis to identify additional existing and new literature … If a meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates from … Carbohydrate quantity in the dietary management of type 2 diabetes: A systematic review and meta-analysis … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report

364. Medication Errors | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/medication-errors
     February 01, 2024 - Respiratory Tract Infections Research Protocol Archived July 30, 2015 Critical Analysis … Respiratory Tract Infections Research Protocol Archived December 6, 2011 Critical Analysis

365. Omega-3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
     August 12, 2016 - Raitt 2005 is in the current meta-analysis. … Raitt 2005 is in the current meta-analysis. … included approximately two thirds fewer RCTs compared to the GOED-sponsored meta-analysis. … compared to the GOED-sponsored meta-analysis. … As noted, it was necessary to restrict the number of studies for analysis.

366. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
     January 10, 2012 - In 2008, Schmitt and colleagues published a meta-analysis analyzing the efficacy and tolerability of … Systematic reviews with or without meta-analysis will be included for manual reference searching as … We will conduct sensitivity analysis limiting the analysis to only trials rated as good quality. … For example, when a meta-analysis is performed, we will evaluate the confidence interval around the … Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88. PMID: 3802833. 22.

367. Disposition of Comments Report for Decision Aids for Cancer Screening and Treatment (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
     December 23, 2014 - It also adds to the knowledge base through the detailed analysis of effect modifiers. … A meta-analysis was done. … The endorsed analysis (hierarchical random effects meta-regression analysis) could incorporate both … We did not undertake a subgroup analysis specific to PSA testing. … We refer to (Bayesian analysis) credible intervals.

368. Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
     September 02, 2016 - Deviations from the protocol’s analysis plan may be suggestive of selective analysis reporting. … ), or a change in statistical significance (by meta-analysis). … Detecting and adjusting for small-study effects in meta-analysis. … Meta-analysis, funnel plots and sensitivity analysis. Biostatistics. 2000 Sep;1(3):247-62. … INTENTION-TO-TREAT analysis?

369. Prostate-Cancer-Test Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
     October 14, 2011 - : adjustment for potential confounders and intention-to-treat analysis Quality will be assessed … [Note: Irrelevant if only the data and analysis from the systematic review are used in this CER and … Matched Analysis For each individual matched study, the data can most likely be summarized in one … This software supports meta-analysis of both matched and unmatched data. … DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancer.

370. Fibromyalgia Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
     January 01, 2015 - Because fibromyalgia is largely a chronic condition in adults, we limited our analysis to studies of … A third type of study was a pooled analysis of individual patient data from several RCTs to report … Two RCTs with high risk of bias3,63 and one pooled IPD RCT analysis of four RCTs of duloxetine with … Nonoverlapping outcomes information was included for the pooled analysis in this review. … Systematic review and network meta-analysis of interventions for fibromyalgia: a protocol.

371. Strategies to Improve Mental Health Care for Children and Adolescents | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mental-health-children/research-protocol
     March 01, 2020 - If we conduct quantitative syntheses (i.e., meta-analysis), we will assess statistical heterogeneity … We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Random-effects meta-analysis of inconsistent effects: a time for change. … This information will contextualize the published data and inform additional analysis described below … In addition to the planned analysis, we will use quantitative comparative analysis (QCA) using the dataset

372. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
     December 01, 2011 - Data Synthesis and Analysis We qualitatively examined data from all identified studies. … Nine RCTs,6,23-25,28,29,33,40,42 an individual patient data meta- analysis,81,82 a pooled analysis,83 … Bias in meta- analysis detected by a simple, graphical test. … Adjunctive devices in primary or rescue PCI: a meta-analysis of randomized trials. … Sensitivity analysis: A ”what if ” analysis that helps determine the robustness of a study.

373. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
     May 01, 2006 - Number of studies reporting 6 15 3 Patients analyzed 2,205 3,293 659 Pooled relative risk of Hb Meta-analysis … increase >2 mg/dL (95% CI) not done1 3.42 (3.03, 3.86)2 3.36 (2.48, 4.56) Pooled event rates (range Meta-analysis … Results of this fixed-effects meta-analysis were compared with random-effects meta-analysis; results … , and quantitative analysis could not be performed for the 15 remaining studies. … Analysis of mortality in all 40 trials shows no overall benefit of darbepoetin or epoetin on survival

374. Mindfulness-Based Interventions for Mental Health and Wellbeing in Children and Adolescents: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/ped-mindfulness/protocol
     October 01, 2024 - , network meta-analysis). … Symptoms of depression and anxiety in youth with type 1 diabetes: a systematic review and meta-analysis … Mindfulness-based interventions for youth with anxiety: a systematic review and meta-analysis. … An updated meta-analysis of randomised controlled trials. … Network meta-analysis of multicomponent interventions.

375. Fourth Symposium on Comparative Effectiveness Research Methods: From Efficacy to Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cer-methods-4th-symposium/overview
     November 01, 2018 - erythropoietin stimulating agents on survival in end stage renal disease: a comparison of payment policy analysis … erythropoietin stimulating agents on survival in end stage renal disease: a comparison of payment policy analysis … Targeted maximum likelihood estimation in safety analysis. Lendle SD, Fireman B, van der Laan MJ. … Targeted maximum likelihood estimation in safety analysis.

376. Depression in Children: Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/childhood-depression/protocol
     October 01, 2020 - (i.e., meta-analysis) of the data from those studies. … A systemic review and meta-analysis of the effectiveness of interpersonal psychotherapy for adolescents … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report. … ”[pt] OR “meta-analysis”[ti] OR “systematic literature review”[ti] OR “this systematic review”[tw] OR … ”[pt] OR “meta-analysis”[ti] OR “systematic literature review”[ti] OR “this systematic review”[tw] OR

377. Updating Comparative Effectiveness Reviews: Current Efforts in AHRQ’s Effective Health Care Program | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-updates/methods
     December 01, 2019 - If the original report includes a meta-analysis, a quantitative signal is considered. … A survival analysis. Ann Intern Med 2007;147(4):224-233. Garritty C, Tricco A, Sampson M, et al. … Cumulative meta-analysis of therapeutic trials for myocardial infarction. … Cumulative meta-analysis of clinical trials builds evidence for exemplary medical care. … Cumulative meta-analysis: a consideration of indicators of sufficiency and stability.

378. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/copd/protocol
     January 01, 2019 - If meta-analysis is deemed appropriate, we plan to use the DerSimonian and Laird random effect method … Global and regional estimates of COPD prevalence: Systematic review and meta-analysis. … Clinical outcomes and cost analysis of exacerbations in chronic obstructive pulmonary disease. … Economic analysis of the Confronting COPD survey: an overview of results. … Meta-analysis in clinical trials. Controlled clinical trials. 1986 Sep;7(3):177-88.

379. Disposition of Comments for CERs 155 156 Contast-Induced Nephropathy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
     January 07, 2016 - Interestingly, although this study is excluded from the analysis of CIN, it is included in the analysis … In the analysis of IOCM vs LOCM, it is not clear why an analysis by type of LOCM was not performed … A new analysis has been added to the statin section comparing statin plus NAC v NAC alone. … Through this analysis (conducted because new studies were identified that addressed this comparison … This study seems to not have been included in the analysis (figure 3, or 4).

380. Health-Careassociated-Infections Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_executive.pdf
     November 01, 2012 - Articles also had to include statistical analysis comparing baseline and postintervention infection … 5 • If potential confounders existed, were they controlled for in the analysis? … • For interrupted time-series designs, was an interrupted time-series analysis used? 5. … The words “analysis” and “study” are used interchangeably and refer to the infection-level results. … for net savings, and no studies provided a comprehensive analysis of return on investment.