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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - A sub-analysis of the KIMS database. Growth Horm IGF Res
2005;15:349-359. … Sensitivity Analyses: A ‘what if’ analysis that helps determine the robustness of a study. … Statistical Heterogeneity: Variability in the observed effects among studies in a meta-analysis. … Analysis of cystic fibrosis referrals for lung
transplantation. … Longitudinal analysis of pulmonary function
decline in patients with cystic fibrosis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
April 01, 2024 - We
did not conduct a meta-analysis. … reduction in HAI incidence, but this benefit was not seen when the analysis
was restricted to only … • A meta-analysis found more anxiety and depression in patients who were in
infectious isolation … : A systematic review and meta-
analysis. … Making health care safer: a critical
analysis of patient safety practices.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
March 26, 2013 - An analysis of claims from one large insurer
demonstrated that the most common indication for colorectal … We argue that the retracted study should not be included at all in a meta-analysis. … The determination on the appropriateness of meta-analysis will be made before any data
analysis; we … will not base the decision to perform meta-analysis on statistical criteria for
heterogeneity. … Network meta-analysis for indirect treatment comparisons. Stat Med 2002 Aug
30;21:2313-24.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - (meta-analysis performed if new
evidence was large relative to the studies in the original meta-analysis … ); consistency in findings
between the new studies and the original meta-analysis (meta-analysis performed … performed if the strength of evidence based on the original meta-analysis was low
or insufficient and … Opioids for chronic low back pain
management: a Bayesian network meta-
analysis. … A Systematic Review and
Meta-Analysis. Arthritis Care Res
(Hoboken). 2020 Jun 25;25:25.
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effectivehealthcare-admin.ahrq.gov/products/saturated-fat-replacement/protocol
November 01, 2024 - confounders Analyses of dietary fat as a continuous variable (e.g., RR per g/day intake) without an analysis … be considered to be at moderate risk of bias If there are no major concerns about study design or analysis … and control for potential confounders was conducted with propensity score analysis (or equivalent), … Dietary fats and mortality among patients with type 2 diabetes: analysis in two population based cohort … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report.
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effectivehealthcare-admin.ahrq.gov/products/mhs4-failure-rescue/protocol
September 01, 2023 - We will not conduct a meta-analysis. … Analysis of Subgroups or Subsets
We will perform a sub-group analysis for pediatric … Effects of rapid response systems on clinical outcomes: systematic review and meta-analysis. … Rapid Response Teams: A Systematic Review and Meta-analysis. … Rapid response systems: a systematic review and meta-analysis.
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effectivehealthcare-admin.ahrq.gov/products/registries-guide-2nd-edition/research
October 01, 2019 - Medicaid Services, commissioned a guide to provide practical, scientific advice on the design, operation, analysis … were added on emerging challenges and controversies in registry planning, design, ethics, management, analysis … "Registry Design" (Chapter 3) and "Analysis and Interpretation" (Chapter 13) were reorganized to be more … Health Records (EHRs)
Chapter 12: Adverse Event Detection, Processing, and Reporting
Chapter 13: Analysis
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
April 01, 2013 - adverse cardiovascular events (MACE)
and coronary dissection were significantly
lower in the overall analysis … One new meta-analysis
reported better outcomes in
patients treated with
aspiration thrombectomy
than … One new meta-analysis
reported no difference in
outcomes in patients treated
with mechanical
thrombectomy … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID: 17638714.
4. … Evidence Table
Author, year Study design Comparison Sample size Results
Kumbhani, 20136 Meta-analysis
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - Their analysis seems to be
biased. … , but this
analysis was not prespecified. … The result in the ITT analysis
was not statistically significant, and while
the per-protocol analysis … We further
considered the responder analysis,
which favored BT, but note that this
analysis was not … Analysis of results for the
intention-to-treat population found no
improvement, but analysis of results
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
December 09, 2013 - The
determination on the appropriateness of meta-analysis will be made before any data
analysis. … Meta-analysis of the clinical and laboratory diagnosis of
appendicitis. … A meta-analysis. Saudi Med J.2007
Feb;28(2):173-80. [PMID: 17268692]
12. … A Meta-Analysis. Radiology. 2006 Oct;241(1):83-
94. … MR imaging in cases of antenatal
suspected appendicitis--a meta-analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
March 13, 2013 - Mass Spectrometry versus Immunoassay: In renal transplants, does mass
from Nominator: spectrometric analysis … and therapeutic monitoring of tacrolimus as compared with
immunoassay analysis and therapeutic monitoring … monitoring of the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus, how does
mass spectrometric analysis … compare with immunoassay analysis for: 1) organ survival,
2) acute and long-term rejections, 3) nephrotoxicity
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effectivehealthcare-admin.ahrq.gov/products/disruptive-behavior-disorder/research-protocol
December 01, 2019 - We will examine the appropriateness of each study for inclusion in a meta-analysis. … The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … I: A meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD. … the analysis, reporting, and claim of subgroup effects in randomized trials.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
June 05, 2014 - Meta-analysis: chronic disease self-management
programs for older adults. … Behavioural interventions for type 2 diabetes: an evidence-
based analysis. … Diabetes patient education: a meta-analysis and meta-
regression. … Random effects meta-analysis of inconsistent
effects: a time for change. … Quantifying heterogeneity in a meta-analysis. Stats Med.
2002;21(11):1539-58.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
March 01, 2025 - The linear dose-response meta-analysis showed a significant
association between the risk of incident … Subgroup Analysis Based on Sex and Geographic Location
We found no significant linear dose-response … • Dose-response meta-
analysis also showed
nonsignificant
associations. … Subgroup Analysis Based on Sex and Geographic Location
We found similar U-shaped nonlinear dose-response … is important to
acknowledge the limitations of study-level meta-regression and dose-response meta-
analysis
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effectivehealthcare-admin.ahrq.gov/products/transparency-neuropathy/research-protocol
June 01, 2021 - Population
Total enrollment, sample size in each arm, drop-outs
Participants included in analysis … pre-specified primary outcomes, number of primary outcomes
Description of secondary outcome
Analysis … Description of the pre-specified statistical analysis plan
Results of primary and secondary … If a meta-analysis is possible, sensitivity analysis, running analysis with and without the information … Notably, according to an analysis by Zarin and colleagues, out of 2178 clinical trials with posted results
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_disposition-comments.pdf
March 01, 2012 - These two studies
provided a small amount of events to the
overall analysis as well. … For example,“KQ3 (analysis of
covariates)
Although we agree this would help to remind
the reader … Was
meta-analysis of subgroup data, estimates of association, or
meta-regression not possible? … Additionally, the design and results of each
review/analysis were reviewed to make
comparisons with … Peer Reviewer #3 Results This sensitivity analysis on good trials, instead, should have been
graded
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - 15.3 years for living donor transplants in 2009-2010.2 Survival rates continue to
improve; a recent analysis … Decisions about whether meta-analysis is appropriate will
depend on the judged clinical homogeneity … A refined method for the
meta-analysis of controlled clinical trials with
binary outcome. … Random-effects meta-analysis of inconsistent
effects: a time for change. … Validity of statistical analysis and reporting adequacy: Was the statistical analysis
performed appropriately
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
January 01, 2014 - Whether to use it in an analysis as
rigorous as the current study is questionable. … This meta-analysis should be shown. … This analysis has real
validity issues and should be either redone or removed. … We also changed the analysis to use the
adjusted or propensity-scored HRs in the meta-
analysis to reduce … Unfortunately, we do not have individual patient-level
data available for analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-function_disposition-comments.pdf
August 11, 2014 - We decided to keep the meta-
analysis figures sorted by cutpoints but
mentioned the lack of temporal … The data
analysis and synthesis are appropriate for this type of meta-analysis. … Therefore a meta-analysis could have
been conducted with the limitations cited. … The number of subjects enrolled in to each trial could also
be shown in the meta-analysis. … We do not think a cumulative meta-analysis
will help to address our Key Questions.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
September 01, 2016 - any)
Population Total enrollment, sample size in each arm, drop-outs
Participants included in analysis … of pre-specified primary outcomes, number
of primary outcomes
Description of secondary outcome
Analysis … Description of the pre-specified statistical analysis plan
Results of primary and secondary out- … If a
meta-analysis is possible, sensitivity analysis, running analysis with and without the information … Notably, according to an analysis by Zarin and
colleagues, out of 2178 clinical trials with posted