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281. - (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
     January 01, 2009 - A sub-analysis of the KIMS database. Growth Horm IGF Res 2005;15:349-359. … Sensitivity Analyses: A ‘what if’ analysis that helps determine the robustness of a study. … Statistical Heterogeneity: Variability in the observed effects among studies in a meta-analysis. … Analysis of cystic fibrosis referrals for lung transplantation. … Longitudinal analysis of pulmonary function decline in patients with cystic fibrosis.

282. Major-Depressive-Disorder Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
     November 24, 2014 - (i.e., meta-analysis) of the data from those studies. … We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Antidepressant drug effects and depression severity: a patient-level meta-analysis. … Psychotherapy for depression in adults: a meta-analysis of comparative outcome studies. … Brief psychotherapy for depression: a systematic review and meta-analysis.

283. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
     February 01, 2015 - Random-effects meta-analysis of inconsistent effects: a time for change. … Random-effects model for meta-analysis of clinical trials: an update. … How do you use existing risk of bias in a modified or new analysis? … studies to adding the new studies and rerunning the existing analysis. … Scenario 3 Use review with new or modified analysis Will do a new analysis if the existing analysis

284. Chronic-urinary-retention-protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research-protocol.pdf
     November 19, 2012 - We will therefore use clinicaltrials.gov to identify studies that specify CUR subgroup analysis in their … Data fields to be abstracted will be determined based upon proposed summary analysis. … Investigator assessment of these items will compare reported results to planned analysis described in … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have … as Topic/ (12608) 54 meta analy$.tw. (43811) 55 metaanaly$.tw. (1130) 56 Meta-­‐Analysis/ (37918)

285. Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
     March 01, 2025 - The linear dose-response meta-analysis showed a significant association between the risk of incident … Subgroup Analysis Based on Sex and Geographic Location We found no significant linear dose-response … • Dose-response meta- analysis also showed nonsignificant associations. … Subgroup Analysis Based on Sex and Geographic Location We found similar U-shaped nonlinear dose-response … is important to acknowledge the limitations of study-level meta-regression and dose-response meta- analysis

286. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - , without attempting to incorporate the new studies into the meta-analysis. … When analyzing newer studies to add to the analysis of Griebeler et al, it appears that these newer … studies were not added to the meta- analysis, but instead taken individually and directly compared … We had made this decision to be consistent with Griebeler et al. meta-analysis that we were using … We have conducted a new meta- analysis in this section, including unpublished trials.

287. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - , without attempting to incorporate the new studies into the meta-analysis. … When analyzing newer studies to add to the analysis of Griebeler et al, it appears that these newer … studies were not added to the meta- analysis, but instead taken individually and directly compared … We had made this decision to be consistent with Griebeler et al. meta-analysis that we were using … We have conducted a new meta- analysis in this section, including unpublished trials.

288. Psychosocial and Pharmacologic Interventions for Disruptive Behavior Disorder | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/disruptive-behavior-disorder/research-protocol
     December 01, 2019 - We will examine the appropriateness of each study for inclusion in a meta-analysis. … The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … I: A meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD. … the analysis, reporting, and claim of subgroup effects in randomized trials.

289. Colorectal-Surgery-Preparation Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
     March 26, 2013 - An analysis of claims from one large insurer demonstrated that the most common indication for colorectal … We argue that the retracted study should not be included at all in a meta-analysis. … The determination on the appropriateness of meta-analysis will be made before any data analysis; we … will not base the decision to perform meta-analysis on statistical criteria for heterogeneity. … Network meta-analysis for indirect treatment comparisons. Stat Med 2002 Aug 30;21:2313-24.

290. EHC Protocol: Recurrent Nephrolithiasis in Adults and Children: Comparative Effectiveness of Preventive Medical Strategies (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
     September 24, 2024 - (when available), serum chemistries, and urine analysis for first-time stone formers, with 24-hour … have a preference for this workup.3 Some authorities claim that optimal treatment includes metabolic analysis … If outcomes are quantitatively synthesized, we will conduct a sensitivity analysis excluding studies … Comparison of four heterogeneity measures for meta-analysis. … Bias in meta-analysis detected by a simple, graphical test.

291. Healthcare Industry Waste and Lifecycle Assessment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lifecycle-assessment
     September 01, 2023 - Life cycle analysis (LCA) provides a pathway to evaluate products, processes, and procedures within a … A limitation in the analysis may be unknown associated impacts at various points from cradle to grave … What data sources, measures/indicators, and methods were used in the analysis? … The technical brief will provide a trend analysis showing the interest in LCAs over time. … LCA data quality: sensitivity and uncertainty analysis.

292. Transparency of Reporting Requirements: Effectiveness of Treatments Options for the Prevention of Complications and Treatment of Symptoms of Diabetic Peripheral Neuropathy | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/transparency-neuropathy/research-protocol
     June 01, 2021 - Population Total enrollment, sample size in each arm, drop-outs Participants included in analysis … pre-specified primary outcomes, number of primary outcomes Description of secondary outcome Analysis … Description of the pre-specified statistical analysis plan Results of primary and secondary … If a meta-analysis is possible, sensitivity analysis, running analysis with and without the information … Notably, according to an analysis by Zarin and colleagues, out of 2178 clinical trials with posted results

293. Disposition of Comments for CER 202 Effectiveness and Safety of Bronchial Thermoplasty in the Management of Asthma (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
     December 14, 2017 - Their analysis seems to be biased. … , but this analysis was not prespecified. … The result in the ITT analysis was not statistically significant, and while the per-protocol analysis … We further considered the responder analysis, which favored BT, but note that this analysis was not … Analysis of results for the intention-to-treat population found no improvement, but analysis of results

294. Speakerbiosketches Deliberativemethodswebinar1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/speakerbiosketches_deliberativemethodswebinar1.pdf
     May 23, 2012 - Associate Member, Department of Political Science Member, Centre for Health Economics and Policy Analysis … include the design and evaluation of public engagement to inform health system decision making; the analysis … of the role of public values in health policy; and the analysis of the determinants of health policy … Yegian received a PhD in Health Services and Policy Analysis from the University of California at Berkeley

295. Menopausal Symptoms: Comparative Effectiveness Review of Therapies | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/menopause/research-protocol
     December 01, 2019 - Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis. … Schwarzer G. meta: Meta-Analysis with R (version 1.6-1). … Subset: Systematic Review OR Publication Type: Meta-analysis OR (“meta-analysis” OR metaanalysis OR “ … Intention to treat analysis is performed. … Intention to treat analysis is lacking.

296. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - adverse cardiovascular events (MACE) and coronary dissection were significantly lower in the overall analysis … One new meta-analysis reported better outcomes in patients treated with aspiration thrombectomy than … One new meta-analysis reported no difference in outcomes in patients treated with mechanical thrombectomy … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID: 17638714. 4. … Evidence Table Author, year Study design Comparison Sample size Results Kumbhani, 20136 Meta-analysis

297. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - The determination on the appropriateness of meta-analysis will be made before any data analysis. … Meta-analysis of the clinical and laboratory diagnosis of appendicitis. … A meta-analysis. Saudi Med J.2007 Feb;28(2):173-80. [PMID: 17268692] 12. … A Meta-Analysis. Radiology. 2006 Oct;241(1):83- 94. … MR imaging in cases of antenatal suspected appendicitis--a meta-analysis.

298. Diabetes-Behavior-Programs Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
     June 05, 2014 - Meta-analysis: chronic disease self-management programs for older adults. … Behavioural interventions for type 2 diabetes: an evidence- based analysis. … Diabetes patient education: a meta-analysis and meta- regression. … Random effects meta-analysis of inconsistent effects: a time for change. … Quantifying heterogeneity in a meta-analysis. Stats Med. 2002;21(11):1539-58.

299. Disposition of Comments CER 219 Antipsychotics for the Prevention and Treatment of Delirium (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
     September 03, 2019 - Could the authors please add more language to the methods section on the use of meta analysis. … Decisions on what to pool in a meta-analysis can often be subjective. … We considered conducting a meta-analysis of length of stay in hospital. … Meta-analysis of median values is generally not acceptable and we determined that transformation of … It’s unclear why only three of the RCTs were included in the meta-analysis.

300. Interventions to Improve Appropriate Antibiotic Use for Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research-protocol
     December 01, 2020 - In consultation with our statistician, we will consider a network analysis to make comparisons across … When meta-analysis cannot be performed, the data will be summarized qualitatively, grouping studies by … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002 Jun 15;21(11):1539-58. … Methods for meta-analysis in medical research. Chichester: J. Wiley; 2000. Lewis S, Clarke M. … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have