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effectivehealthcare-admin.ahrq.gov/sites/default/files/data-extraction.ppt
January 01, 2009 - Meta-analysis: combining the results of independent experiments. … Berlin J, for the University of Pennsylvania Meta-analysis Blinding Study Group. … Does blinding of readers affect the results of meta-analysis? Lancet 1997;350:185-6. … Does blinding of readers affect the results of meta-analysis? Lancet 1997;350:185-6. … Meta-analysis: combining the results of independent experiments.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - decision analysis
approach. … Benefit-Less-Risk Analysis
Benefit-less-risk analysis (BLRA) combines benefit and harm into a single … Multicriteria Decision Analysis
Multicriteria decision analysis allows for systematic decisionmaking … Probabilistic analysis and sensitivity
analysis are two examples of quantitative approaches that reviewers … Studies included in
a network meta-analysis should be, as in any conventional meta-analysis, comparable
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effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-prognostic/methods
December 01, 2019 - A meta-analysis could provide more precise estimates of outcome probabilities. … A meta-analysis of randomized control trials. Circulation 1990;82(4):1106-16. … Anemia and mortality in heart failure patients: a systematic review and meta-analysis. … Decision curve analysis: a novel method for evaluating prediction models. … Meta-analysis of summary survival curve data. Stat Med 2008;27(22):4381-96.
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effectivehealthcare-admin.ahrq.gov/products/liver-cancer/research
December 01, 2019 - studies was assessed, data were extracted, and results were summarized quantitatively (through meta-analysis … Analyses were stratified by imaging type and unit of analysis (patient or HCC lesion). … settings, based on studies that directly compared imaging modalities and using HCC lesions as the unit of analysis … sensitivity included use of explanted liver as the reference standard, use of HCC lesions as the unit of analysis … Imaging techniques for the diagnosis of hepatocellular carcinoma: a systematic review and meta-analysis
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - Study and Independent Patient Level Meta-Analysis Selection:
Results from study- and patient-level meta-analysis … Did the analysis include an intention-to-treat analysis? … The hazards of scoring the quality of clinical
trials for meta-analysis. … meta: Meta-Analysis, R package version 1.5-0.
55. R Development Core Team. 2010. … metafor: Meta-Analysis Package for R. R package version
1.1-0.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
January 01, 2014 - However, use of the gold standard synovial fluid
analysis for diagnosis of gout is difficult and seldom … In fact,
evidence from a 2011 survey of rheumatologists suggests that SF analysis is underused in
the … Studies will also be included if
they compare the accuracy of synovial fluid aspiration and analysis … Comparators will be
microscopic synovial fluid analysis. … Bias in meta-analysis detected by a
simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
November 19, 2009 - Decision analysis is a natural framework to assess such tradeoffs. … How to use a clinical decision analysis.
B. … Meta-
analysis of diagnostic tests with
imperfect reference standards. … Regression
methods for meta-analysis of diagnostic
test data. … Endoscopic colorectal cancer screening:
a cost-saving analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - It may be of
interest to include analysis comparing those who are
nullipara to those who have been … Narod study--
included in the table but excluded from meta analysis?) … This seems like a
reasonable exploratory analysis potentially? … Our systematic review incorporates a meta-analysis
of published data rather than a pooled analysis or … individual patient-level meta-analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f-surv-rept-1-acute-pain.xlsx
September 21, 2022 - Intention-to-Treat Analysis? Post-Randomization Exclusions? Outcomes
Prespecified? … Yes Yes Yes Yes No/No No No Yes Fair
Desjardins, 2020 Yes Yes Yes Yes Yes Yes Yes No/No Yes; full analysis
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effectivehealthcare-admin.ahrq.gov/products/benefits-harms-modeling/research
November 01, 2017 - Decision analysis is a natural framework to assess such tradeoffs. … How to use a clinical decision analysis. B. … Meta-analysis of diagnostic tests with imperfect reference standards. … Regression methods for meta-analysis of diagnostic test data. … Endoscopic colorectal cancer screening: a cost-saving analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
August 01, 2007 - We restricted the analysis to just APM initiators to guard
against selection bias among prevalent users … A multivariable analysis of the mortality difference estimated an increase of 3.5 per 100 (95%
CI: 2.7 … Analysis using
instrumental variables. … Sensitivity analysis of the observed association between conventional APM use and death. … year adjusted analysis of death within 180 days 1.11 (1.04-1.19)
Multivariable adjusted analyses of
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effectivehealthcare-admin.ahrq.gov/system/files/docs/topic-brief-hospital-length-of-stay.pdf
November 01, 2019 - Enhanced Recovery after Bariatric Surgery: Systematic
Review and Meta-Analysis. … and Trial Sequential
Analysis of Evidence. … : A Systematic Review and Meta-analysis of Major Abdominal Surgery. … Traditional vs ERAS radical cystectomy: systematic review, meta-
analysis and trial sequential analysis … No subgroup analysis is planned.
• Processes. Two reviews looked at healthcare processes.
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effectivehealthcare-admin.ahrq.gov/products/crohns-disease/research-protocol
December 01, 2019 - Because of the recent high quality meta-analysis focused on treatment options after surgical resection … A sensitivity analysis will include study populations with all levels of disease severity. … A sensitivity analysis will include study populations with all levels of disease severity. … The TEP does not do analysis of any kind nor contribute to the writing of the report. … Sensitivity analysis for KQ3 will include inflammatory bowel disease not specified.
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effectivehealthcare-admin.ahrq.gov/products/antipsychotics-children-update/research-protocol
April 01, 2020 - ), the type of analysis (e.g., subgroup/stratified or regression analysis), the outcomes assessed (dependent … versus usual care) through standard meta-analysis, a network meta-analysis allows for simultaneous evaluation … Chapter 9: Analyzing data and undertaking meta-analysis. … Bayesian methods in meta-analysis and evidence synthesis. … to network meta-analysis.
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effectivehealthcare-admin.ahrq.gov/products/major-depressive-disorder/research-protocol
December 01, 2019 - (i.e., meta-analysis) of the data from those studies. … We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Antidepressant drug effects and depression severity: a patient-level meta-analysis. … Psychotherapy for depression in adults: a meta-analysis of comparative outcome studies. … Brief psychotherapy for depression: a systematic review and meta-analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
December 01, 2009 - A recent meta-analysis showed an increased risk of
cardiovascular mortality,17 while this meta-analysis … This resulted in 17 medication regimens included in the analysis. … Only in the analysis in which patients with baseline hospitalizations
were excluded did we not find … Tiotropium for stable chronic
obstructive pulmonary disease: A meta-
analysis. … Pooled clinical trial analysis of
tiotropium safety. Chest 2006
Dec;130(6):1695-703.
20.
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effectivehealthcare-admin.ahrq.gov/products/colorectal-surgery-preparation/research-protocol
December 01, 2019 - We argue that the retracted study should not be included at all in a meta-analysis. … The determination on the appropriateness of meta-analysis will be made before any data analysis; we … will not base the decision to perform meta-analysis on statistical criteria for heterogeneity. … Network meta-analysis for indirect treatment comparisons. Stat Med 2002 Aug 30;21:2313-24. … Meta-analysis in clinical trials. Control Clin Trials 1986 Sep;7(3):177-88. PMID: 3802833.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - Our analysis identified important
discrepancies in effect sizes, with meta-analyses of both published … The third study (#29060/627)
yielded mixed (equivocal) results: the intent-to-treat analysis using the … and responder analysis using CGI-I did not show significant associations. … a Statistically significant benefit shown in the LOCF analysis of CAPS-2 score but not in the observed … case analysis of CAPS
score or in CGI-I responder analysis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - For example, in a
sensitivity analysis of a meta-analysis on the risk of nausea and vomiting during … : no limit
For qualitative analysis: n ≥ 40
Key Question 2a:
Maintenance of remission
Study … A “poor” rating indicates significant bias (e.g., stemming from serious errors in
design or analysis … (meta-analysis) of data from those studies. … The TEP does not do analysis of any kind nor
contribute to the writing of the report.
X.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
November 29, 2023 - .36 When meta-analysis is not possible, we
will provide a qualitative synthesis. … When meta-analysis is possible, we will synthesize
data using a Hartung, Knapp, Sidik, and Jonkman … If meta-analysis is not possible, we will present results in a
narrative Summary of Findings table. … Protein Intake and Sarcopenia in
Older Adults: A Systematic Review and Meta-Analysis. … Meta-Analysis with R. 2015.
39. Higgins JP, Thompson SG, Deeks JJ, Altman DG.