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461. Healthcare Cost and Utilization Project (HCUP) KID Notes
     hcup-us.ahrq.gov/db/vars/uncbwtcharge/kidnote.jsp
     September 01, 2008 - Cost-to-Charge Ratio (CCR) Files Hospital Market Structure (HMS) Files Supplemental Variables for Revisit Analyses … DISCWT should be used to create national estimates for all analyses except those that involve total charge

462. Systemic vulnerabilities to suicide among veterans from the Iraq and Afghanistan conflicts: review of case reports from a national Veterans Affairs database. | PSNet
     psnet.ahrq.gov/issue/systemic-vulnerabilities-suicide-among-veterans-iraq-and-afghanistan-conflicts-review-case
     January 22, 2017 - February 10, 2021 Root cause analyses of reported adverse events occurring during gastrointestinal … September 19, 2016 Root cause analyses of suicides of mental health clients.

463. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression—An Update to a 2007 Report. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
     December 01, 2011 - To some extent we could overcome this issue by conducting meta-analyses. … Peer Reviewer #5 Methods Pg 33, line 30 “…included meta-analyses in this CER…” Comment: delete meta-analyses … Did you use it in analyses? Qualitative synthesis - e.g. stratification? … Above mentioned results are based on meta-analyses of head to- head trials. … We use bullet points just for the listing of meta- analyses.

464. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
     December 01, 2011 - We conducted separate analyses for studies that enrolled patients experiencing only STEMI, studies that … For all analyses, a p-value of <0.05 was considered statistically significant. … These analyses were conducted to assess the methodological study quality (analyses limited to “good” … Data from RCTs, observational studies, and individual patient data meta- analyses were utilized. … and analyses limited to good-quality trials.

465. Screening for Child and Adolescent Depression in Primary Care Settings: A Systematic Evidence Review (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/R33bUm6oyjhWnbw96pJHwE
     April 01, 2009 - Data were also available from 4 other meta- analyses that calculated the pooled relative risk (RR) or … , as well as Bayesian methods of meta-analyses. … Meta-analyses also differed in terms of calculat- ing RR or RD. … The FDA analyses used fixed-effects models to calculate RDs and risk ratios. … All meta-analyses were conducted by using RevMan 4.2 software (Cochrane Collaboration.

466. Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
     November 19, 2009 - We do not explicitly discuss costs and cost-effectiveness analyses, nor do we provide guidelines and … Instead, we highlight specific examples to help readers appreciate the role of formal quantitative analyses … Decision analyses assessed tradeoffs associated with the choices to give vidarabine empirically, withhold … In an evidence report, cost-effectiveness analyses contrasted 17 technologies (tests) and 4 combinations … All readers of decision analyses should be mindful of the assumptions that are invoked when estimates

467. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - Revised accordingly Methods Throughout the report and appendix, statistical analyses (e.g., odds … In systematic reviews statistical analyses are conducted by systematic review methodologists. … higher dose analyses. … Please make correction for other such analyses in the report. … These separate analyses were nothing but exploration of heterogeneity of the more general analyses!

468. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/43040/psn-pdf
     March 05, 2014 - Framework for analysing risk and safety in clinical medicine. March 5, 2014 Vincent C, Taylor-Adams S, Stanhope N. Framework for analysing risk and safety in clinical medicine. BMJ. 1998;316(7138):1154-1157. https://psnet.ahrq.gov/issue/framework-analysing-risk-and-safety-clinical-medicine-0 This commentary outli…

469. Renal-Function Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
     August 01, 2014 - For KQ 3 , there was insufficient data for conducting meta- analyses. … For KQ 4 , we conducted two types of meta- analyses. … Studies were too few to generate meta-analyses for subgroup type. … , whereas Khan et al. only performed relative risk analyses. … This limited our ability to pool data and perform meta-analyses.

470. Interventions in Primary Care to Promote Breastfeeding: An Evidence Review (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/WYuzSoTB7frsav2gnsP7SR
     January 01, 2010 - Limitations: Meta-analyses were limited by clinical and method- ological heterogeneity. … Subgroup Analyses We performed subgroup analyses according to various study factors, such as study quality … We used Intercooled Stata, version 8.2 (Stata, College Station, Texas) for all analyses. … Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60. [PMID: 12958120] 91. … , such as subgroup analyses and adjusted analyses. ¶ Downgraded to poor quality because only 64.7% of

471. Aspirin for the Primary Prevention of Cardiovascular Events: A Systematic Evidence Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/wBcZfBcVp8N3-cyT3Peysv
     April 01, 2016 - In analyses of all doses, aspirin reduced the risk for nonfatal myocardial infarction (MI) (relative … Detailed methods and secondary outcome analyses are available in our full report (18). … Sensitivity analyses of trials with doses of 100 mg or less per day yielded similar Figure 2. … designated analyses a priori. … The best infor- mation came from controlled multivariable analyses Table 2.

472. Arthritis-Knee-Physical-Therapy Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_executive.pdf
     November 01, 2012 - We developed the protocol following Preferred Reporting Items for Systematic Reviews and Meta-Analyses … Only 84 RCTs met pooling criteria and were included into meta-analyses. … Different reporting formats precluded pooled analyses. … ▪ Pain did not differ between electrical stimulation and exercise in pooled analyses. … Adjustment of meta- analyses on the basis of quality scores should be abandoned.

473. Meditation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
     October 17, 2012 - For studies amenable to pooling with meta-analyses, we will calculate pooled mean differences, risk … We will conduct sensitivity analyses by omitting one study at a time to assess the influence of any … All meta-analyses will be conducted using STATA (Intercooled, version 11, StataCorp, College Station … We will conduct meta-analyses when there is sufficient data (at least 3 studies that sufficiently … For studies amenable to pooling with meta-analyses, we will calculate pooled mean differences, risk

474. Showing Health Information Value in a Community Network - 2008 | Digital Healthcare Research
     digital.ahrq.gov/ahrq-funded-projects/showing-health-information-value-community-network/annual-summary/2008
     January 01, 2008 - Analyses were delayed at least 6 months after the completion of each study phase to ensure that the claims … As a consequence of these delays, preliminary analyses have not been performed for all phases. … Grantee’s Most Recent Self-Reported Status (as of August 2008): Data collection and some preliminary analyses

475. MAINTAIN AND EXPAND (pdf file)
     hcup-us.ahrq.gov/reports/methods/2011_03.pdf
     January 01, 2011 - Additional observations from the literature review, survey, data analyses, and interviews conducted … The data analyses showed that 6% of SEDD records and 18% of SASD records had a chronic first-listed … The results are summarized below, although no further data analyses were conducted. … available at the time that the analyses were conducted. … FINDINGS Findings from SEDD Analyses In 2008, 28 states contributed to the SEDD.

476. Treatment of Osteoarthritis of the Knee: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
     June 15, 2016 - To the extent data are available to allow it, we will conduct subgroup analyses to assess early vs. … , or more appropriately, whether new meta-analyses can be conducted, since the Hartung Knapp method … the results of the earlier meta-analyses narratively. … If new meta- analyses are done, these findings will be reported quantitatively with forest plots. … Prior meta-analyses will be treated as one study.

477. Quantitative Synthesis: Chapter 2. Presenting Different Effects for Different Data Types (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
     February 01, 2018 - Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. … Ratio (RR) - Easily interpretable - Commonly reported in individual trials considered in meta-analyses … even with differing baseline risks - Commonly reported in individual trials considered in meta-analyses … easily interpretable - Can be misleading when interpreted like relative risks - Widespread use in meta-analyses … Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

478. Calculating Variances Using the 1999 Nationwide Inpatient Sample (pdf file)
     hcup-us.ahrq.gov/reports/methods/2003_02.pdf
     January 01, 2003 - This is important, because unweighted statistics and analyses that fail to account for the NIS sample … Several statistical programming packages allow weighted analyses. … One of the difficulties analysts will face with this approach is the requirement to perform analyses … Types of estimands and statistical analyses that can be accommodated. … Types of estimands and statistical analyses that can be accommodated.

479. HCUP Methods Series Calculating Nationwide Inpatient Sample (NIS) Variances for Data Years 2011 and Earlier
     hcup-us.ahrq.gov/reports/methods/2003_02.jsp
     January 01, 2003 - This is important, because unweighted statistics and analyses that fail to account for the NIS sample … Several statistical programming packages allow weighted analyses. … One of the difficulties analysts will face with this approach is the requirement to perform analyses … Longitudinal analyses of hospital-level outcomes may be biased if they are based on any subset of NIS … Types of Estimands and Statistical Analyses That Can Be Accommodated SAS/STAT Software now provides

480. Final Research Plan: Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/ocular-prophylaxis-for-gonococcal-ophthalmia-neonatorum-preventive-medication
     February 08, 2018 - Development Index Study design KQ 1: Randomized, controlled trials; systematic reviews and meta-analyses … KQ 2: Randomized, controlled trials; systematic reviews and meta-analyses; cohort studies, case-control