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61. 4Nuuvs6Nmztdbgjbg3Elke (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/4NUuvS6nmzTdBgjBg3ELkE
    January 01, 2020 - We did random-effects meta-analyses for 5 or more studies using the DerSimonian–Laird method to estimate … Outcome analyses were also stratified by length of follow-up after randomiza- tion (short term was less … We did all analyses using Stata, version 11.2. … Of the 71 trials, only 14 could not be included in meta-analyses of inter- mediate health outcomes, … We used the DerSimonian–Laird method for random-effects meta-analyses, which has known limita- tions

62. Screening for Hepatitis B Virus Infection in Pregnant Women: Evidence for the Reaffirmation Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/mEtSwJk3YPA4BXJ8eZyD2S
    June 01, 2009 - Selection: For benefits of screening and newborn prophy- laxis, we included systematic reviews; meta-analyses … For harms of screening, we included system- atic reviews; meta-analyses; randomized, controlled trials … benefits of prenatal screening for HBV infection, we included randomized, controlled trials; meta-analyses … For harms of screening, we in- cluded systematic reviews; meta-analyses; randomized, con- trolled trials

63. Final Research Plan: Breast Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/breast-cancer-screening
    May 06, 2021 - How do new findings, analyses, or longer-term followup from foundational effectiveness trials of mammography … Nations Development Programme)   Study Design KQs 1, 2: Individual participant data meta-analyses

64. Evidence Summary: Chronic Obstructive Pulmonary Disease: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chronic-obstructive-pulmonary-disease-screening
    May 10, 2022 - Results: The review included no trials on the effectiveness of screening, 3 trials or analyses (n = … pharmacologic treatment (KQ3). 24 , 25 Three studies were identified since 2015 with newly published analyses … trial (n = 5993) 8 was included in the previous review but had 2 newly published post hoc subgroup analyses … COPD or who were minimally symptomatic (based on GOLD criteria), or studies that reported subgroup analyses … inhaled corticosteroids can reduce COPD exacerbations in persons with moderate COPD In a small subgroup analyses

65. Archived: Evidence Summary: Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors: Behavioral Counseling | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary2/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
    August 26, 2014 - We did random-effects meta-analyses for 5 or more studies using the DerSimonian–Laird method to estimate … Outcome analyses were also stratified by length of follow-up after randomization (short term was less … We did all analyses using Stata, version 11.2. … Fourteen trials could not be included in meta-analyses due to limitations in reporting at the primary … We used the DerSimonian–Laird method for random-effects meta-analyses, which has known limitations 93

66. Screening for Depression in Adult Patients in Primary Care Settings: An Update (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/-wqedxmwdpdE5BmzcBeTmn
    December 01, 2009 - to good-quality randomized clinical trials or controlled clinical trials; systematic reviews; meta-analyses … Seven regulatory reviews or meta- analyses and 3 large cohort studies indicate no increased risk for … Methods for incorporating systematic reviews and meta-analyses are detailed elsewhere (Appendix Table … Overall, these meta- analyses suggested no increase in suicide but did suggest age-related effects on … We reported specific analyses of most relevance where possible.

67. Archived: Published Comments and Response: Aspirin for the Prevention of Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/published-comments-and-response/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
    October 15, 2009 - Other trials involving women had far fewer patients than the Women's Health Study, and subgroup analyses … In general, the USPSTF is cautious when considering unplanned subgroup analyses of randomized trials, … All subgroup analyses should be considered hypothesis-generating rather than independently persuasive

68. Archived: Falls Prevention in Community-Dwelling Older Adults: Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/falls-prevention-in-older-adults-interventions-2018
    April 17, 2018 - Based on pooled analyses of 15 studies (n=4926), exercise interventions reduced the number of persons … However, given that these findings were only exploratory analyses to evaluate causes of heterogeneity … Pooled analyses found reductions in the number of falls among participants who received multifactorial … Pooled analyses showed neither a significant reduction in falls (IRR, 0.97 [95% CI, 0.79 to 1.20]; 5 … Pooled analyses revealed statistically significant reductions in 1 fall-related outcome (number of falls

69. Screening for Obstructive Sleep Apnea in Adults: Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
    January 01, 2017 - When multiple similar studies were available, random-effects meta-analyses were conducted. … Analyses were by AHI thresholds cor- responding to OSA severity categories. … Thirty-four trials reported sufficient ESS data to include in meta-analyses. … Twenty-nine trials reported sufficient blood pressure data to include in meta-analyses. … Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-560. 26. Cohen J.

70. Archived: Evidence Summary: Alcohol Misuse: Screening and Behavioral Counseling Interventions in Primary Care | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary9/alcohol-misuse-screening-and-behavioral-counseling-interventions-in-primary-care-2013
    September 25, 2012 - The Figure shows the forest plots for 12-month outcomes from our meta-analyses for adults. … Subgroup analyses identified no significant differences between men and women. … Measuring inconsistency in meta-analyses. BMJ . 2003;327:557-60. … All percentages are absolute risk differences from our meta-analyses. … The data for young adults are from Project TrEAT subgroup analyses (226 participants).

71. Archived: Evidence Summary: Latent Tuberculosis Infection: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
    September 06, 2016 - To determine whether meta-analyses were appropriate, the number of studies available and the clinical … All quantitative analyses were conducted using Stata version 13.1 (StataCorp). 14 Sensitivity analyses … Detailed findings related to these analyses are in the full evidence report. … IUAT trial and RCTs used in sensitivity analyses f published >30 y ago. … IUAT trial and RCTs used in sensitivity analyses k published >30 y ago.

72. Modeling Study: Breast Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/breast-cancer-screening
    April 30, 2024 - These models were included in the 2 previous decision analyses conducted for the USPSTF. 9 , 10 Since … Population for Analysis These analyses modeled a single cohort of US women with no personal history … Analyses were repeated for Black women and for strata according to density category, elevated relative … In sensitivity analyses, for comparison with previous modeling in 2009 and 2016, we repeated the analysis … Finally, some analyses were based on findings from fewer than 6 models for pragmatic reasons.

73. Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
    April 01, 2016 - Study Selection: Randomized, controlled trials; cohort studies; and meta-analyses comparing aspirin with … We used the Peto odds ratio (OR) for primary statistical analyses (17) because of rare events (that is … , a control group event rate <1%) and repeated analyses using the Mantel–Haenszel OR; in both methods … Some subgroup analyses (for example, proton- pump inhibitor or statin use) were not specified a priori … We also identified 2 IPD meta-analyses (8, 15) of included trials that re- ported harms analyses complementing

74. Evidence Summary: Gestational Diabetes: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/gestational-diabetes-screening
    August 10, 2021 - , differing outcome definitions); findings of within study subgroup analyses were extracted. … For diagnostic accuracy, analyses were stratified by timing of the index test in pregnancy and comparison … Prespecified analyses found screening in first trimester was significantly associated with decreased … The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomized Studies in Meta-analyses … What contributions do languages other than English make on the results of meta-analyses?

75. Final Evidence Summary: Illicit Drug Use in Children, Adolescents, and Young Adults: Primary Care-Based Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/other-supporting-document19727/drug-use-illicit-primary-care-interventions-for-children-and-adolescents
    September 03, 2020 - Pooled analyses of the general prevention trials were conducted using random-effects meta-analyses on … Additionally, analyses of cannabis-specific results in native units are provided. … Stata version 15.1 (StataCorp) was used for all analyses. … However, these studies generally found benefits only in subgroup analyses, and the pattern of results … Summary of Sensitivity Analyses of Primary Drug Outcome (KQ2) for General Prevention Trials: Results

76. Evidence Gaps Research Taxonomy Table: Primary Care Behavioral Counseling Interventions to Support Breastfeeding (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/5newnV_sfH4xnGCbpoh4Ma
    who experience disparities in breastfeeding rates in sufficient numbers for preplanned subgroup analyses … who experience disparities in breastfeeding rates in sufficient numbers for preplanned subgroup analyses

77. Collaborative Modeling of U.S. Breast Cancer Screening Strategies (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/nmcMhEwWT9BncBBBQQN6Uf
    December 01, 2015 - Finally, we conducted sensitivity analyses and analyses validating the models. … Sensitivity analyses examining a range of disutility values did not change conclusions of the analyses … Separate analyses with this model produced results that were congruent with those from analyses based … The overall conclusions were also similar across models for mostly all analyses. … Sensitivity Analyses Chapter 4.

78. Archived: Evidence Summary: Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Risk Factors: Behavioral Counseling | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
    July 11, 2017 - Within each study, 1-year outcome data were chosen for meta-analyses if available; otherwise, the point … Stata version 13.1 (Stata Corp) was used for all quantitative analyses. … Meta-analyses stratified by diet-only messages, physical activity–only messages, or combined diet and … Such a priori analyses could assist in identifying groups of adults who might benefit more from such … For most outcomes, the statistical heterogeneity of pooled analyses was unimportant ( I 2 < 40%) or

79. Collaborative Modeling of U.S. Breast Cancer Screening Strategies (pdf file)
    www.uspreventiveservicestaskforce.org/Home/GetFile/1/16255/collabmodelingbc/pdf
    December 01, 2015 - Finally, we conducted sensitivity analyses and analyses validating the models. … Sensitivity analyses examining a range of disutility values did not change conclusions of the analyses … Separate analyses with this model produced results that were congruent with those from analyses based … The overall conclusions were also similar across models for mostly all analyses. … Sensitivity Analyses Chapter 4.

80. Evidence Summary: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-adults-preventive-medication
    April 17, 2018 - In addition, the full evidence report includes results from sensitivity analyses not reported here. … Sensitivity analyses were conducted using RCTs excluded for poor quality and RCTs excluded because of … A case study of discordant overlapping meta-analyses: vitamin D supplements and fracture. … Seven of the poor-quality RCTs were used in the sensitivity analyses. … c Ten RCTs (in 13 articles) were used in sensitivity analyses for KQ1; 4 were excluded from the main