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201. Screening for Anxiety in Children and Adolescents: Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/oZSntFpszryu7mAnjdhkrw
     September 05, 2023 - articles, and study quality and extracted data; when at least 3 similar studies were available, meta-analyses … pro- vided in eTable 20, detailed outcomes are provided in eTables 21 and 22, and results from meta-analyses … Few studies reported analyses for populations of interest. … Stud- ies reporting on analyses of anxiety symptoms consistently re- ported no differences in effect … Analysing data and undertaking meta-analyses.

202. Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
     August 23, 2022 - factors were dyslipidemia (which was variably defined), diabetes, and hypertension. 13 , 31 In pooled analyses … (RR, 0.68 at 6 years [95% CI, 0.48 to 0.98]; ARD, −0.70% [95% CI, −1.36% to −0.05%]). 33 In pooled analyses … In stratified analyses, the relative benefits of statin therapy did not appear to differ across a variety … In pooled analyses of trial data, statin therapy was not associated with increased risk of study withdrawal … difference between statin therapy and placebo in risk of elevation in aminotransferase levels, and pooled analyses

203. Recommendation: Breastfeeding: Primary Care Behavioral Counseling Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/breastfeeding-primary-care-interventions
     April 11, 2025 - and 6 months) varied from 27 to 51 trials (N analyzed, 10,622 to 17,580). 29 , 30 Based on pooled analyses … Exploratory analyses suggest that interventions may be more effective in women who were not initially … to determine if any differences between control and intervention groups existed, since many of these analyses … Early life exposures and the risk of inflammatory bowel disease: systematic review and meta-analyses.

204. Archived: Low-Dose Aspirin Use for the Prevention of Morbidity and Mortality From Preeclampsia: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication-september-2014
     September 09, 2014 - Sensitivity analyses using an alternate method for estimating pooled random effects resulted in similar … However, the analyses were confounded by unequal distribution of sample sizes in different dosage categories … Pooled analyses showed no statistically significant increase in abruption associated with aspirin (RR … Pooled analyses (14 studies; n = 22,848) on perinatal mortality (RR, 0.92 [95% CI, 0.76 to 1.11];

205. Screening for Syphilis Infection in Pregnant Women: Evidence for the Reaffirmation Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/gWJU-ZynehGyLBVYtDmMow
     May 01, 2009 - Randomized, controlled trials; meta-analyses; systematic reviews; cohort studies; and ecologic studies … Random- ized, controlled trials; meta-analyses; systematic reviews; cohort studies; case–control studies … the prevalence of congenital syphilis in neonates, we included randomized, controlled trials; meta-analyses … harms of syphilis screening and penicillin treatment, we included randomized, controlled trials; meta- analyses

206. Screening for Suicide Risk in Adults: A Summary of the Evidence (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/cJSpoZqW2M7czx_-GeTdtE
     May 01, 2004 - either adults only or adults and older adolescents but did not differentiate further by age in the analyses … Specifically, meta-analyses of RCTs using problem-solving therapy have shown benefit, as indicated by … this void.36 Subsequent research should involve populations with more clearly defined age groups and analyses … Retrospective analyses have suggested that educating general practitioners on better identification and … MEDLINE® PsycINFO 1 Primary care reviews or meta-analyses 54 47 2 Total unduplicated records from

207. Archived: Final Evidence Summary: Suicide Risk: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary48/suicide-risk-screening-2004
     May 15, 2004 - either adults only or adults and older adolescents but did not differentiate further by age in the analyses … Specifically, meta-analyses of RCTs using problem-solving therapy have shown benefit, as indicated by … Retrospective analyses have suggested that educating general practitioners on better identification and … Randomized controlled trials; cross-sectional studies; cohort studies; systematic reviews; and meta-analyses … MEDLINE® PsycINFO 1 Primary care reviews or meta-analyses

208. Primary Care Interventions to Support Breastfeeding: Updated Evidence Report and Systematic Review (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/kHDoNjsfLx9SyKGD5n2ufL
     January 01, 2020 - Pooled estimates based on random-effects meta-analyses using the DerSimonian and Laird method indicated … The data on health outcomes (KQ1) and adverse events (KQ3) did not allow for pooled analyses and so were … and the total number of participants randomized for each group were entered into random-effects meta-analyses … Sensitiv- ity analyses using a restricted maximum-likelihood model with the Knapp-Hartung modification … were run for all meta-analyses that re- sulted in substantial heterogeneity (I2 > 50%).25 All statistically

209. Recommendation: Colorectal Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
     May 18, 2021 - by the USPSTF in 2016 included analyses with elevated risk scenarios to reflect recent population trends … in colorectal cancer incidence 15 and analyses by race. 12 , 13 Accuracy of Screening Tests The … reported results by age strata and generally found no significant difference; 2 reported stratified analyses … In modeling analyses, performing sDNA-FIT every 3 years or high-sensitivity gFOBT annually (also included … No studies included persons younger than 50 years and no subgroup analyses on harms by age were reported

210. Archived: Final Evidence Summary: Coronary Heart Disease: Screening Using Non-Traditional Risk Factors | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary16/coronary-heart-disease-screening-using-non-traditional-risk-factors-2009
     October 15, 2009 - † From meta-analyses of cohort studies unless otherwise noted. … In addition, analyses were not limited to intermediate-risk persons, and the quality of adjustment for … However, the sensitivity of these subgroup analyses was poor, and we could not rule out differences in … C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses … Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses.

211. Archived: Comparative Effectiveness of Antiviral Treatment for Hepatitis C Virus Infection in Adults: A Systematic Review: Hepatitis C: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/comparative-effectiveness-of-antiviral-treatment-for-hepatitis-c-virus-infection-in-adults-a-systematic-review/hepatitis-c-screening-2013
     November 15, 2012 - We performed meta-analyses of trials that evaluated similar populations, interventions, comparisons, … Statistical heterogeneity was explored through sensitivity and subgroup analyses based on study quality … Analyses were performed with Stata software, version 11.0 (Stata Corp, College Station, Texas). … We did not perform formal analyses for publication bias because of the small numbers of trials, but analyses … Meta-analyses were performed by using the DerSimonian–Laird random-effects model, which results in CIs

212. Primary Care Behavioral Counseling Interventions to Support Breastfeeding: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/r77BgfGVeBPRDME-DpBvFk
     April 08, 2025 - months, and 6 months) varied from 27 to 51 trials (N analyzed, 10 622 to 17 580).29,30 Based on pooled analyses … Exploratory analyses suggest that interventions may be more effective in women who were not ini- tially … to determine if any differences between control and intervention groups existed, since many of these analyses … Early life exposures and the risk of inflammatory bowel disease: systematic review and meta-analyses.

213. Final Evidence Summary: Depression and Suicide Risk in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary27/screening-depression-suicide-risk-children-adolescents
     October 11, 2022 - articles, and study quality and extracted data; when at least 3 similar studies were available, meta-analyses … trials are new to this update. 52-55 , 58 , 60 , 64-72 The results in this publication focus on pooled analyses … included in pooled results are provided in eTables 29 and 30 in the Supplement, and results from meta-analyses … Analysing data and undertaking meta-analyses. … Suicidal Ideation Questionnaire– Junior; SMD, standardized mean difference. a Results from pooled analyses

214. Final Research Plan: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Falls and Fractures in Community-Dwelling Adults: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/vitamin-d-calcium-combined-supplementation-primary-prevention-falls-fractures-communitydwelling-adults
     April 06, 2023 - by Whitlock et al, 1 which involves identifying and assessing credibility of within-study subgroup analyses

215. Interventions to Support Breastfeeding: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/SJbAXUAQTv2GWemMuBab6W
     April 08, 2025 - Pooled analyses indicated beneficial associations between breastfeeding support interventions and any … For breastfeeding out- comes (KQ2), random-effects meta-analyses were conducted using the restricted … Meta-regression and strati- fied analyses were conducted to explore whether there were popu- lation or … In meta-analyses, there was a statistically significant association Figure 2. … The forest plots for all pooled analyses can be found in eFigures 1 through 9 in the Supplement.

216. Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: USPSTF Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/by8VJVre6h6BmadrGxaFMM
     April 01, 2016 - Subpopulation analyses evaluated effect modifica- tion of aspirin by age, sex, and diabetes status. … Analyses of trials using the range of aspirin doses showed similar results. … Pooled analyses of low-dose aspirin trials showed an increased risk for hemorrhagic stroke (OR, 1.27 … Pooled analyses of 9 trials of any dose showed a significant 33% increase in hemorrhagic stroke (OR, … When combined with primary trial data and meta- analyses, the model provides an additional analytic ba

217. Archived: Hepatitis B Virus Infection: Screening, 1996 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-b-virus-infection-screening-1996
     January 01, 1996 - eligibility for vaccination, but recommendations for screening may be made based on cost-effectiveness analyses … eligibility for vaccination, but recommendations for screening may be made based on cost-effectiveness analyses … Such analyses suggest that screening is usually cost-effective in groups with an HBV marker prevalence

218. Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years: A Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/9AtjNaSwTXonz49w_DEbNz
     November 07, 2023 - - ing bias, and applicability, using the approach described in the USPSTF Procedure Manual.14 Meta-analyses … Analyses were conducted strati- fying on relevant factors, including placebo or no treatment con- trol … small study effects was not performed because the meta-analyses had fewer than 10 studies.17 Results … Fifth, meta- analyses had substantial statistical heterogeneity. … To address sta- tistical heterogeneity, random-effects models were used and strati- fied analyses on

219. Update on the Methods of the U.S. Preventive Services Task Force: Estimating Certainty and Magnitude of Net Benefit (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4y3P9DxovKMEjNmVd2mrPp
     December 01, 2007 - Although formal decision analyses and cost-effec- tiveness analyses have been proposed as an objective … method to weigh benefits and harms, the Task Force rec- ognizes that such analyses can be complex and

220. Final Research Plan: Tobacco Smoking Cessation in Adults, Including Pregnant Persons: Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
     July 12, 2018 - or at risk of tobacco use–related morbidity will be included, as will results from credible subgroup analyses