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21. Final Research Plan: Latent Tuberculosis Infection in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/latent-tuberculosis-infection-screening
    June 17, 2021 - KQ 3: Systematic reviews and meta-analyses (including network meta-analyses), ‡  and RCTs.  … KQ 4: Systematic reviews, RCTs, and prospective cohort studies KQ 5: Systematic reviews and meta-analyses … (including network meta-analyses), RCTs, prospective cohort studies, and case-control studies.

22. Aspirin for the Prevention of Cancer Incidence and Mortality: Systematic Evidence Reviews for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Njxn2r3qtWKdBf2_VhS2Aw
    April 01, 2016 - For total cancer, we based our review on 2 individual-patient data (IPD) meta-analyses of randomized, … We used Stata 12.0 (StataCorp) for all statistical analyses. … Inclusion and exclusion criteria used in the 4 included meta-analyses are compared in Table 2. … Analyses did not clearly suggest an effect of the dose (12). … Thus, we focused on RCTs and IPD meta-analyses to enhance validity.

23. Nontraditional Risk Factors in Cardiovascular Disease Risk Assessment: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
    July 17, 2018 - For KQ2, individual participant data meta-analyses, trials, and well-designed prospective cohort studies … Quantitative analyses were not conducted because of the limited number of studies for each KQ or method … For the Framingham Risk Score–based analyses, which used 3 risk strata, the top 2 risk strata (10%-20% … In the individual pa- tient data meta-analysis model development analyses, base model performance was … C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses

24. Evidence Summary: Healthy Weight and Weight Gain In Pregnancy: Behavioral Counseling Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/healthy-weight-and-weight-gain-during-pregnancy-behavioral-counseling-interventions
    May 25, 2021 - In stratified analyses, there were no statistically significant interactions between associations of … Stratified analyses showed statistically significant interactions between effect of GWG interventions … In stratified analyses, effect estimates of GWG interventions on likelihood of LGA did not differ by … Some stratified analyses were underpowered to evaluate subgroup effects. … Measuring inconsistency in meta-analyses.

25. Colorectal Cancer Screening: An Updated Modeling Study for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/473PPVwoRhapCkN9SC-rue
    May 18, 2021 - Scenario analyses were also simulated assuming IRRs of 1.00 (no change in incidence from the prescreening … Analyses by Race and Sex In consultation with the USPSTF, analyses were conducted by race and sex for … Scenario Analyses For each modality, efficient strategies were similar for the 3 colo- rectal cancer … These analyses were carried out before publi- cation of recent reviews demonstrating limited evidence … However, both analyses found that starting screening at age 45 years provided an efficient balance of

26. Evidence Summary: Aspirin Use to Prevent Cardiovascular Events: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer
    April 11, 2016 - In analyses of all doses, aspirin reduced the risk for nonfatal myocardial infarction (MI) (relative … We abstracted subgroup analyses for these groups and considered their credibility based on the timing … We evaluated subgroup analyses qualitatively because those reported were too limited to pool. … when compared with analyses using all doses. … , and only 2 37 , 39 clearly designated analyses a priori.

27. Archived: Evidence Summary: Aspirin Use to Prevent Cardiovascular Events: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - In analyses of all doses, aspirin reduced the risk for nonfatal myocardial infarction (MI) (relative … We abstracted subgroup analyses for these groups and considered their credibility based on the timing … We evaluated subgroup analyses qualitatively because those reported were too limited to pool. … when compared with analyses using all doses. … , and only 2 37 , 39 clearly designated analyses a priori.

28. 6Ngc3Byq9Jeby Pwyvd6Or (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/6Ngc3byQ9jeBy_pwyvD6or
    September 01, 2014 - We conducted sensitivity analyses using profile likeli- hood random-effects methods when our meta-analyses … We did not include poor- quality studies in our analyses. … Analyses were conducted using Stata, version 11.1 (StataCorp). … main analyses, with only minor variation in width of CIs (Table 2). … Negative RDs favor CEA. ‡ Analyses did not have small numbers of studies.

29. Evidence Summary: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
    August 23, 2022 - Data Synthesis and Analysis Meta-analyses were conducted to calculate risk ratios (RRs) for statins … Results were generally consistent in sensitivity and stratified analyses. … of study-level data and within study stratified analyses. … However, excluding these trials from analyses did not affect findings. … Measuring inconsistency in meta-analyses.

30. Draft Research Plan: Syphilis Infection During Pregnancy: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/syphilis-infection-pregnant-persons
    December 01, 2022 - widespread screening program with historical or geographic comparator; systematic reviews and meta-analyses … ; case-control studies; diagnostic accuracy studies; large case series; systematic reviews and meta-analyses

31. Modeling Study: Cervical Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/cervical-cancer-screening
    August 21, 2018 - In all analyses, primary hrHPV testing strategies occurring at 5-year intervals were efficient. … In most analyses, strategies involving cotesting were not efficient. … Sensitivity analyses assessed the effect of test performance characteristics on the main results. … In analyses that introduced error in the performance of colposcopy and biopsy in classifying a woman’ … Each of these sensitivity analyses resulted in similar efficient strategies as in the base-case analyses

32. Evidence Summary: Iron Deficiency and Iron Deficiency Anemia During Pregnancy: Screening and Supplementation | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    August 20, 2024 - Data Synthesis Meta-analyses using the DerSimonian-Laird random-effects model (STATA version 14.2 [ … Table 1 reports the results of meta-analyses, including analyses stratified by country and dose; forest … plots for the primary meta-analyses are provided in eFigures 1-8 in the  JAMA  Supplement. … Findings were similar when analyses were stratified by country HDI category and dose. … However, the utility of stratified analyses was limited by relatively small numbers of trials.

33. Archived: Final Evidence Summary: Depression in Children and Adolescents: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary21/depression-in-children-and-adolescents-screening-2009
    March 15, 2009 - Data were also available from 4 other meta-analyses that calculated the pooled relative risk (RR) or … , as well as Bayesian methods of meta-analyses. … Meta-analyses also differed in terms of calculating RR or RD. … The FDA analyses used fixed-effects models to calculate RDs and risk ratios. … All meta-analyses were conducted by using RevMan 4.2 software (Cochrane Collaboration.

34. Archived: Final Evidence Summary: Vitamin D and Calcium to Prevent Fractures: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary52/vitamin-d-and-calcium-to-prevent-fractures-preventive-medication-2013
    December 10, 2011 - Data Synthesis For analyses of RCTs included for KQ 1, we used the DerSimonian-Laird random-effects … Analyses were conducted by using Stata SE 11 software (StataCorp, College Station, Texas). … Measuring inconsistency in meta-analyses. BMJ . 2003;327:557-60. … The strengths and limitations of meta-analyses based on aggregate data. … Go to the Appendix for methods used for the dose–response meta-analyses.

35. Final Research Plan: Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/aspirin-use-to-prevent-cardiovascular-disease-preventive-medication
    May 14, 2020 - KQ 1: Randomized, controlled trials; controlled clinical trials; and individual patient data meta-analyses … KQ 2: Randomized, controlled trials; controlled clinical trials; individual patient data meta-analyses

36. Final Research Plan: Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/aspirin-to-prevent-cardiovascular-disease-preventive-medication
    May 14, 2020 - KQ 1: Randomized, controlled trials; controlled clinical trials; and individual patient data meta-analyses … KQ 2: Randomized, controlled trials; controlled clinical trials; individual patient data meta-analyses

37. Screening for Cervical Cancer in Primary Care: A Decision Analysis for the U.S. Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/HZGtYqL_8u57Gkc6YFctmT
    August 21, 2018 - In all analyses, primary hrHPV testing strategies occurring at 5-year intervals were efficient. … In most analyses, strategies involving cotesting were not efficient. … intraepithelial lesion (base-case analyses assumed ASCUS), varying in- tervals for follow-up testing … remained stable under both sensitivity analyses, with slight decreases in the ratios attrib- utable … Each of these sensitivity analyses resulted in similar efficient strategies as in the base-case analyses

38. Draft Research Plan: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/aspirin-use-to-prevent-cardiovascular-disease-and-colorectal-cancer-preventive-medication
    January 30, 2020 - KQ 1: Randomized, controlled trials; controlled clinical trials; and individual patient data meta-analyses … KQ 2: Randomized, controlled trials; controlled clinical trials; individual patient data meta-analyses

39. Draft Research Plan: Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/aspirin-use-to-prevent-cardiovascular-disease-preventive-medication
    January 30, 2020 - KQ 1: Randomized, controlled trials; controlled clinical trials; and individual patient data meta-analyses … KQ 2: Randomized, controlled trials; controlled clinical trials; individual patient data meta-analyses

40. Final Research Plan: Syphilis Infection During Pregnancy: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-pregnant-persons
    March 02, 2023 - widespread screening program with historical or geographic comparator; and systematic reviews and meta-analyses … case-control studies; diagnostic accuracy studies; large case series; and systematic reviews and meta-analyses