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101. Evidence Summary: Chronic Obstructive Pulmonary Disease: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chronic-obstructive-pulmonary-disease-screening
     May 10, 2022 - Results: The review included no trials on the effectiveness of screening, 3 trials or analyses (n = … pharmacologic treatment (KQ3). 24 , 25 Three studies were identified since 2015 with newly published analyses … trial (n = 5993) 8 was included in the previous review but had 2 newly published post hoc subgroup analyses … COPD or who were minimally symptomatic (based on GOLD criteria), or studies that reported subgroup analyses … inhaled corticosteroids can reduce COPD exacerbations in persons with moderate COPD In a small subgroup analyses

102. Evidence Summary: Vitamin D Deficiency: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary18/vitamin-d-deficiency-screening
     November 25, 2014 - For analyses with between-study heterogeneity, we conducted sensitivity analyses using profile likelihood … Sensitivity analyses resulted in similar findings of no effect and did not decrease heterogeneity. … Sensitivity analyses did not affect findings. … Sensitivity and stratified analyses on these factors, however, did not affect conclusions. … Measuring inconsistency in meta-analyses. BMJ . 2003;327:557-60. [PMID: 12958120] 68.

103. Archived: Evidence Summary: Vitamin D Deficiency: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary18/vitamin-d-deficiency-screening-november-2014
     November 25, 2014 - For analyses with between-study heterogeneity, we conducted sensitivity analyses using profile likelihood … Sensitivity analyses resulted in similar findings of no effect and did not decrease heterogeneity. … Sensitivity analyses did not affect findings. … Sensitivity and stratified analyses on these factors, however, did not affect conclusions. … Measuring inconsistency in meta-analyses. BMJ . 2003;327:557-60. [PMID: 12958120] 68.

104. Screening for Depression in Adult Patients in Primary Care Settings: An Update (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/-wqedxmwdpdE5BmzcBeTmn
     December 01, 2009 - to good-quality randomized clinical trials or controlled clinical trials; systematic reviews; meta-analyses … Seven regulatory reviews or meta- analyses and 3 large cohort studies indicate no increased risk for … Methods for incorporating systematic reviews and meta-analyses are detailed elsewhere (Appendix Table … Overall, these meta- analyses suggested no increase in suicide but did suggest age-related effects on … We reported specific analyses of most relevance where possible.

105. Screening for Obstructive Sleep Apnea in Adults: Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
     January 01, 2017 - When multiple similar studies were available, random-effects meta-analyses were conducted. … Analyses were by AHI thresholds cor- responding to OSA severity categories. … Thirty-four trials reported sufficient ESS data to include in meta-analyses. … Twenty-nine trials reported sufficient blood pressure data to include in meta-analyses. … Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-560. 26. Cohen J.

106. Archived: Evidence Summary: Alcohol Misuse: Screening and Behavioral Counseling Interventions in Primary Care | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary9/alcohol-misuse-screening-and-behavioral-counseling-interventions-in-primary-care
     September 25, 2012 - The Figure shows the forest plots for 12-month outcomes from our meta-analyses for adults. … Subgroup analyses identified no significant differences between men and women. … Measuring inconsistency in meta-analyses. BMJ . 2003;327:557-60. … All percentages are absolute risk differences from our meta-analyses. … The data for young adults are from Project TrEAT subgroup analyses (226 participants).

107. Archived: Evidence Summary: Alcohol Misuse: Screening and Behavioral Counseling Interventions in Primary Care | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary9/alcohol-misuse-screening-and-behavioral-counseling-interventions-in-primary-care-2013
     September 25, 2012 - The Figure shows the forest plots for 12-month outcomes from our meta-analyses for adults. … Subgroup analyses identified no significant differences between men and women. … Measuring inconsistency in meta-analyses. BMJ . 2003;327:557-60. … All percentages are absolute risk differences from our meta-analyses. … The data for young adults are from Project TrEAT subgroup analyses (226 participants).

108. Evidence Summary: Latent Tuberculosis Infection: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening
     September 06, 2016 - To determine whether meta-analyses were appropriate, the number of studies available and the clinical … All quantitative analyses were conducted using Stata version 13.1 (StataCorp). 14 Sensitivity analyses … Detailed findings related to these analyses are in the full evidence report. … IUAT trial and RCTs used in sensitivity analyses f published >30 y ago. … IUAT trial and RCTs used in sensitivity analyses k published >30 y ago.

109. Archived: Evidence Summary: Latent Tuberculosis Infection: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
     September 06, 2016 - To determine whether meta-analyses were appropriate, the number of studies available and the clinical … All quantitative analyses were conducted using Stata version 13.1 (StataCorp). 14 Sensitivity analyses … Detailed findings related to these analyses are in the full evidence report. … IUAT trial and RCTs used in sensitivity analyses f published >30 y ago. … IUAT trial and RCTs used in sensitivity analyses k published >30 y ago.

110. Screening for Atrial Fibrillation With Electrocardiography: Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/crPsNJ_R5SFnJhuT2CEpkr
     March 01, 2019 - When at least 3 similar studies were available, random-effects meta-analyses were conducted. … Methods Scope of Review Detai led methods and additional detai ls of results and analyses are available … To determine whether meta-analyses were appropri- ate, clinical and methodological heterogeneity were … The subgroup analyses reported from the SAFE study found that screening may not increase detection of … Measuring inconsistency in meta-analyses.

111. Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
     April 01, 2016 - Study Selection: Randomized, controlled trials; cohort studies; and meta-analyses comparing aspirin with … We used the Peto odds ratio (OR) for primary statistical analyses (17) because of rare events (that is … , a control group event rate <1%) and repeated analyses using the Mantel–Haenszel OR; in both methods … Some subgroup analyses (for example, proton- pump inhibitor or statin use) were not specified a priori … We also identified 2 IPD meta-analyses (8, 15) of included trials that re- ported harms analyses complementing

112. Modeling Study: Breast Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/breast-cancer-screening
     April 30, 2024 - These models were included in the 2 previous decision analyses conducted for the USPSTF. 9 , 10 Since … Population for Analysis These analyses modeled a single cohort of US women with no personal history … Analyses were repeated for Black women and for strata according to density category, elevated relative … In sensitivity analyses, for comparison with previous modeling in 2009 and 2016, we repeated the analysis … Finally, some analyses were based on findings from fewer than 6 models for pragmatic reasons.

113. Postmenopausal Hormone Replacement Therapy for the Primary Prevention of Chronic Conditions: A Summary of the Evidence for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/sQ7hREGwnBm8Wh-LEFWP4F
     October 01, 2002 - To provide an overview of benefits and harms, we conducted several meta-analyses and used these results … We used only published data in meta- analyses. … were conducted for some of the topics because either previous meta-analyses had not been published, … The logRR and standard errors provided the data points for the meta-analyses. … ).40,71-77 No meta-analyses have evaluated breast cancer mortality.

114. Screening for Testicular Cancer: An Evidence Review for the U.S. Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/677cVB3_YRhoEd3qakdjuS
     September 01, 2010 - Study Selection: Randomized, controlled trials; meta-analyses; sys­ tematic reviews; cohort studies; … Randomized, controlled trials; meta-analyses; systematic reviews; cohort studies; case–control studies … Selection To determine the benefits of screening, we included randomized, controlled trials; meta-analyses … To deter­ mine the harms of screening, we included randomized, controlled trials; meta-analyses; systematic

115. Collaborative Modeling of U.S. Breast Cancer Screening Strategies (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/nmcMhEwWT9BncBBBQQN6Uf
     December 01, 2015 - Finally, we conducted sensitivity analyses and analyses validating the models. … Sensitivity analyses examining a range of disutility values did not change conclusions of the analyses … Separate analyses with this model produced results that were congruent with those from analyses based … The overall conclusions were also similar across models for mostly all analyses. … Sensitivity Analyses Chapter 4.

116. Evidence Summary: Gestational Diabetes: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/gestational-diabetes-screening
     August 10, 2021 - , differing outcome definitions); findings of within study subgroup analyses were extracted. … For diagnostic accuracy, analyses were stratified by timing of the index test in pregnancy and comparison … Prespecified analyses found screening in first trimester was significantly associated with decreased … The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomized Studies in Meta-analyses … What contributions do languages other than English make on the results of meta-analyses?

117. Final Evidence Summary: Illicit Drug Use in Children, Adolescents, and Young Adults: Primary Care-Based Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/other-supporting-document19727/drug-use-illicit-primary-care-interventions-for-children-and-adolescents
     September 03, 2020 - Pooled analyses of the general prevention trials were conducted using random-effects meta-analyses on … Additionally, analyses of cannabis-specific results in native units are provided. … Stata version 15.1 (StataCorp) was used for all analyses. … However, these studies generally found benefits only in subgroup analyses, and the pattern of results … Summary of Sensitivity Analyses of Primary Drug Outcome (KQ2) for General Prevention Trials: Results

118. Final Research Plan: Healthy Diet, Physical Activity, and/or Weight Loss to Prevent Cardiovascular Disease in Adults: Behavioral Counseling Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/behavioral-counseling-interventions-promote-healthy-diet-physical-activity-weight-loss-prevent-cardiovascular-disease-adults
     November 02, 2023 - tolerance, and mixed or multiple risk factors such as 10-year CVD risk >7.5% or metabolic syndrome Analyses … Analyses will include examination of effects by various intervention components such as behavioral focus

119. Evidence Summary: Hormone Therapy in Postmenopausal Women: Primary Prevention of Chronic Conditions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/menopausal-hormone-therapy-preventive-medication
     December 12, 2017 - All quantitative analyses were based on Comprehensive Meta-Analysis Version 3 (Biostat Inc). … Estimates are based on meta-analyses of included trials or, if meta-analyses were not feasible, on results … Analyses that compared younger (50 to 59 years) with older (70 to 79 years) women using estrogen-only … Timing of Intervention Post hoc subgroup analyses of WHI data regarding the association of timing of … , but such analyses were likely underpowered.

120. Archived: Evidence Summary: Hormone Therapy in Postmenopausal Women: Primary Prevention of Chronic Conditions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/menopausal-hormone-therapy-preventive-medication-december-2017
     December 12, 2017 - All quantitative analyses were based on Comprehensive Meta-Analysis Version 3 (Biostat Inc). … Estimates are based on meta-analyses of included trials or, if meta-analyses were not feasible, on results … Analyses that compared younger (50 to 59 years) with older (70 to 79 years) women using estrogen-only … Timing of Intervention Post hoc subgroup analyses of WHI data regarding the association of timing of … , but such analyses were likely underpowered.