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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-screening-2002
September 03, 2002 - We conducted new meta-analyses to incorporate new information about the quality of the trials and longer … In addition, for several of the trials, the most recent analyses correct flaws in earlier reports. … Agency staff and members of the USPSTF reviewed and made substantive recommendations about the analyses … We considered these flaws to be adequately corrected in subsequent analyses by the trialists. … In our assessment of quality, we took into account the results of these supplemental analyses.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/k_QR3hvh2jVSPPLu6Q6m6r
November 13, 2022 - Data Synthesis and Analysis
Meta-analyses were conducted to calculate risk ratios (RRs) for stat-
ins … Results
were generally consistent in sensitivity and stratified analyses. … of study-level data and within-
study stratified analyses. … However, excluding these trials from analyses did not affect findings.Ta
bl
e
2. … Measuring inconsistency in meta-analyses.
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www.uspreventiveservicestaskforce.org/uspstf/document/decision-analysis-for-aspirin/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - Study Perspective
Analyses were conducted from a clinical perspective with respect to health outcomes … Deterministic (1-way) sensitivity analyses of key parameters were conducted with all other parameters … Probabilistic sensitivity analyses can be found in our prior work. 52
Role of the Funding Source … Sensitivity Analyses
One-way parameter sensitivity for men and women with baseline CVD risk of 10% … Nevertheless, discretion should be used when interpreting these results because sensitivity analyses
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www.uspreventiveservicestaskforce.org/uspstf/document/behavioral-counseling-and-pharmacotherapy-interventions-for-/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions-september-2015
September 21, 2015 - We excluded nonsystematic meta-analyses and narrative reviews. … Evidence of beneficial health outcomes were also seen in the pooled analyses across all interventions … A re-analysis of the Cochrane Library data: the dangers of unobserved heterogeneity in meta-analyses. … Pharmacologic-Based Strategies for Smoking Cessation: Clinical and Cost-Effectiveness Analyses. … Fixed-effects models were used in nearly all meta-analyses.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review11/asymptomatic-bacteriuria-in-adults-screening-2008
July 15, 2008 - Selection: For benefits of screening or treatment for screened populations, systematic reviews; meta-analyses … For harms of screening, systematic reviews; meta-analyses; randomized, controlled trials; cohort studies … screening or treatment of screened populations, we included randomized, controlled trials (RCTs); meta-analyses … For harms of screening, we included systematic reviews, meta-analyses, RCTs, cohort studies, case- control
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
August 22, 2023 - Data Synthesis
Meta-analyses of oral PrEP vs placebo or no PrEP were conducted for the 2019 USPSTF … Laird random-effects model 3 ; there were no new placebo-controlled trials to perform updated meta-analyses … Results were consistent in stratified analyses based on follow-up duration, receipt of industry support … Results were similar in stratified analyses based on age (<25 vs ≥25 years), contraception method, and … Findings were robust in subgroup and stratified analyses based on HIV risk category, study duration,
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/sexually-transmitted-infections-behavioral-counseling-september-2014
September 22, 2014 - We stratified our analyses on the basis of age (adolescents vs. adults, including age-based subgroup … We did random-effects meta-analyses for STI incidence using the DerSimonian–Laird method 11 . … We ran sensitivity analyses using the profile likelihood method because some of our pooled estimates … Results shown on forest plots are from the DerSimonian–Laird analyses. … We used Stata, version 11.2 (StataCorp), for all meta-analyses.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-in-children-and-adolescents-screening-2009
March 15, 2009 - Data from meta-analyses of efficacy among children and adolescents, analyzed separately, suggested that … However, meta-analyses of SSRI treatment also demonstrated that fluoxetine is efficacious for treating … Selective Serotonin Reuptake Inhibitors
The USPSTF examined data from fair-quality RCTs and meta-analyses … Conservative estimates from analyses show that treatment with antidepressants leads to a 1 percent to
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary29/hepatitis-b-virus-infection-screening-nonpregnant-adolescents-adults-may-2014
May 27, 2014 - of treatment), although we conducted sensitivity analyses of events during antiviral therapy. … For all analyses, we stratified results by antiviral drug. … of treatment), although we conducted sensitivity analyses of events during antiviral therapy. … For all analyses, we stratified results by antiviral drug. … Measuring inconsistency in meta-analyses. BMJ . 2003;327:557-60. [PMID: 12958120]
17.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary10/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
March 15, 2009 - Study Selection: English-language randomized, controlled trials (RCTs); case-control studies; meta-analyses … For evidence on harms, we limited our search to RCTs, case-control studies, meta-analyses, and systematic … because a blinded end point committee of physicians reviewed medical records for all reported end points, analyses … from aspirin use to a greater or lesser extent than the general population is limited to 3 subgroup analyses … The Women's Health Study performed subgroup analyses by smoking status and age and reported a greater
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/t6yV6ZMHngeWgmTsoMMefM
March 01, 2009 - Study Selection: English-language randomized, controlled trials
(RCTs); case–control studies; meta-analyses … For
evidence on harms, we limited our search to RCTs, case–
control studies, meta-analyses, and systematic … because
a blinded end point committee of physicians reviewed
medical records for all reported end points, analyses … from aspirin use to a greater or lesser extent than
the general population is limited to 3 subgroup analyses … The Women’s Health Study per-
formed subgroup analyses by smoking status and age and
reported a greater
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/unhealthy-alcohol-use-adolescents-adults-behavioral-counseling-interventions
February 01, 2024 - We will also examine selected subgroup analyses reported in the included studies to explore whether broad … Specific analyses of interest will be those stratified by race, ethnicity, sex, gender, and socioeconomic
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/RPB3rmcS9CK_eXPdzXSxZg
July 01, 2010 - Several trials included in the meta-analyses reported
few, rare, or 0 fracture events. … The primary analyses ex
cluded trials with 0 events in both groups, resulting in loss
of data, and … We therefore conducted sensitivity analyses
to determine the effects of alternate pooling methods on … , as well as
other sensitivity analyses. … Sub
group analyses of other bisphosphonates were limited by
few fractures (range, 5 to 18 events).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/wKfFrTpC8VtforKLrqGpjQ
April 18, 2023 - Direct evidence on
screening effectiveness was from 3 nonrandomized analyses of 2 population-based skin … national skin cancer screening program.17,19,23
The first study, which was the only one to include analyses … Sensitivity analyses to assess lead time bias similarly attenuated
both unadjusted (HR, 0.50 [95% CI … 2 German screening programs
reported age- and sex-specific melanoma mortality.17,22,23 Across
these analyses … All direct evidence on the benefits of screening comes from non-
randomized analyses of population-based
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-xiv-decision-framework-assess-and-guide-need-searches-existing-decision-models
July 01, 2017 - Outcomes Research best practices suggest that the modelers search for previously published modeling analyses
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/prevention-of-dental-caries-in-children-younger-than-age-5-years-screening-and-interventions1
December 07, 2021 - Additional subgroup analyses were conducted on use of cluster randomization, follow-up duration, varnish … Although statistical heterogeneity was present, results consistently favored topical fluoride in analyses … Third, statistical heterogeneity was substantial in meta-analyses of topical fluoride. … However, results were consistent in prespecified stratified analyses based on factors related to study … Pooled Analyses of Risk of Caries Development at Follow-up, Topical Fluoride vs Placebo or No Topical
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-children-and-adolescents-screening
June 30, 2022 - In addition to narrative and tabular synthesis, we will conduct meta-analyses if evidence is sufficient … All analyses will be performed using Stata 16.1 (StataCorp, College Station, TX).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TAgAUJ5QoaRfV3M8fApBoN
June 03, 2019 - Meta-analyses using a Bayesian random-
effects model were conducted to provide summary relative risk … In addition, for sev-
eral of the trials, the most recent analyses correct flaws in
earlier reports. … We considered these flaws to be adequately corrected
in subsequent analyses by the trialists. … Meta-Analyses of Randomized Trials of Screening Mammography among Women 40 to 49 Years of Age*
Study … In our assessment of quality, we took into ac-
count the results of these supplemental analyses.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/depression-in-children-and-adolescents-screening
February 08, 2016 - included articles organized as a PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses … No meta-analyses or retrospective cohort studies met our inclusion criteria. … shown but limited publication dates to 2007 or later (2011 or later for systematic reviews and meta-analyses … are included in this report’s qualitative synthesis and 2 studies are included in the quantitative analyses … no studies recruited patients from primary care or school clinic settings
1: Good
3: Fair
Analyses
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review46/hepatitis-b-virus-infection-screening-2004
February 15, 2004 - The search was limited to randomized controlled trials (RCTs), meta-analyses, systematic reviews, editorials … No new RCTs, meta-analyses, or systematic reviews of the evidence for screening in the general population