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81. Drug Therapy for Early Rheumatoid Arthritis in Adults – An Update | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-update/research-protocol
    May 24, 2017 - We will adapt the Cochrane ROB tool 26 for RCT trials by adding items about the statistical analyses … Unlike the prior update, this review will not synthesize relevant SRs or meta-analyses with findings … We will interpret results of such analyses cautiously. … will include them only in sensitivity analyses. … Measuring inconsistency in meta-analyses.

82. Comparative Effectiveness of Terbutaline Pump for the Prevention of Preterm Birth | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
    August 05, 2010 - Exploring heterogeneity The primary analyses for KQ1 and KQ2 are inherently subgroup analyses to assess … Sensitivity analyses Sensitivity analyses are planned to explore the robustness of combined estimates … at high risk of bias; limiting meta-analyses to randomized trials only; and including studies in meta-analyses … Sensitivity analyses will take the form of subgroup analyses as described above. … Sensitivity analyses In addition to the sensitivity analyses outlined above, we will conduct sensitivity

83. Supplemental Project To Assess the Transparency of Reporting for Trials Evaluating Treatment for Infertility | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/transparency-infertility/research
    June 28, 2017 - studies identified there to published studies (to detect publication bias) and (b) compare planned analyses … A secondary goal was to estimate the person-hours required to complete these analyses.

84. M (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/systematicreviewsreplacedenovo.pdf
    September 01, 2009 - • May provide analyses that are not readily available from other sources (e.g., subgroup analyses … • Build on existing SRs by updating meta-analyses or qualitative syntheses. … Quality of Reporting of Meta-analyses. Lancet 1999;354:1896- 900. 8. … Data extraction errors in meta-analyses that use standardized mean differences. … What contributions do languages other than English make on the results of meta- analyses?

85. M (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-de-novo-processes_methods.pdf
    September 01, 2009 - • May provide analyses that are not readily available from other sources (e.g., subgroup analyses … • Build on existing SRs by updating meta-analyses or qualitative syntheses. … Quality of Reporting of Meta-analyses. Lancet 1999;354:1896- 900. 8. … Data extraction errors in meta-analyses that use standardized mean differences. … What contributions do languages other than English make on the results of meta- analyses?

86. ABSTRACT (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning_research.pdf
    September 01, 2012 - We did not exclude duplicates or studies included in prior meta-analyses because these studies were … Such studies were relevant for efficacy/effectiveness analyses, relevant for AE analyses, or irrelevant … We also used these base models to create combination analyses. … , included for both analyses). … , retrospective analyses of claims databases, case- control studies, and analyses of government registries

87. Disposition of Comments for Evidence Report 224 Omega-3 Fatty Acids (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
    October 12, 2016 - We have now added pooled analyses that combine all sources of omega-3 FAs. … We have now added overall pooled analyses to the existing analyses, and show the meta-analyses by type … : Therefore we redid those pooled analyses. … , and consideration of sub-analyses. … we did include in favor of conducting our own de novo analyses.

88. Assessing-The-Risk-Of-Bias-In-Systematic-Reviews-Of-Health-Care-Interventions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
    May 01, 2005 - When reviews include meta-analyses, we recommend that systematic reviewers consider sensitivity analyses … or other independent analyses. … Industry-supported meta-analyses compared with meta-analyses with non-profit or no support: differences … Updating criteria to evaluate the credibility of subgroup analyses. … Measuring inconsistency in meta-analyses. BMJ. 2003 Sep 6;327(7414):557-60.

89. App-E-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
    January 01, 2021 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other … Did the Study Perform Appropriate Statistical Analyses on Potential Confounders?

90. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
    September 01, 2010 - , and biologics to placebo (there are 43 meta-analyses for Crohn’s disease medications; 18 from the … Follow-up duration will be considered in the analyses. … These sensitivity analyses will be compared to our analyses of moderate-to-severe Crohn’s disease. … If we identify such variables explaining inconsistency we will stratify the analyses accordingly. … □ Sensitivity analyses for all Key Questions will include all levels of disease severity.

91. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
    June 01, 2017 - Pairwise meta-analyses were conducted in R using the metafor package. … Network meta-analyses were conducted in R using the gemtc package. … ) analyses. … Ideally, these analyses should be adequately powered. … Almost no studies reported subgroup analyses.

92. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
    June 01, 2017 - Pairwise meta-analyses were conducted in R using the metafor package. … Network meta-analyses were conducted in R using the gemtc package. … ) analyses. … Ideally, these analyses should be adequately powered. … Almost no studies reported subgroup analyses.

93. Evidence-based Practice | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/evidence-based-practice
    September 01, 2019 - September 14, 2021 A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses

94. S166 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s166.pdf
    October 01, 2007 - and Bayesian methods of analysis of indirect comparisons should be considered when performing meta-analyses … We recalculated the direct com- parison frequentist meta-analyses described above using these Bayesian … Prior Sensitivity for Bayesian Analyses All our Bayesian analyses were completely insensitive to the … Direct Comparison—Bayesian The model used for the Bayesian meta-analyses was as follows. … The chosen prior distributions were examined in sen- sitivity analyses.

95. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
    February 01, 2013 - One might expect that all the trials included in earlier meta-analyses would be included in later meta-analyses … Meta- analyses of therapies for postmenopausal osteoporosis. II. … Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. … What contributions do languages other than English make on the results of meta- analyses? … Does blinding of readers affect the results of meta-analyses?

96. Clinical Effectiveness of Coronary Stents in the Elderly: Results From 262,700 Patients in the American College of Cardiology-National Cardiovascular Data Registry | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/coronary-stents-outcomes/research
    February 10, 2010 - The resulting analyses will better inform national practice patterns overall and in important patient … We refer to these latter analyses as 6 and 12 month landmark analyses. … Sensitivity Analyses We conducted two sensitivity analyses. … Registry Versus RCT Results: Sensitivity Analyses The differences in outcomes between registry and … Unadjusted and adjusted results from time-to-event analyses for prespecified endpoints.

97. Radiation Therapy for Brain Metastases: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/radiation-brain-metastases/protocol
    January 28, 2020 - , main analysis, or subgroup analyses. … Chemotherapy, immunotherapy, and radiosensitizer agents will be grouped for the analyses. … subgroup analyses. … Finally, we will present analyses according to how the evidence will be used. … Chapter 11: Undertaking network meta-analyses.

98. Research Protocol: Radiation Therapy for Brain Metastases (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
    October 10, 2019 - , main analysis, 9 or subgroup analyses. … Chemotherapy, immunotherapy, and radiosensitizer agents will be grouped for the analyses. … subgroup analyses. … Finally, we will present analyses according to how the evidence will be used. … Chapter 11: Undertaking network meta- analyses.

99. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
    May 15, 2017 - We will adapt the Cochrane ROB tool26 for RCT trials by adding items about the statistical analyses … All new qualitative and quantitative analyses will synthesize relevant studies included in the 2012 … We will interpret results of such analyses cautiously. … ; we will include them only in sensitivity analyses. … Measuring inconsistency in meta-analyses.

100. Oral Mechanical Bowel Preparation for Colorectal Surgery | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/colorectal-surgery-preparation/research-protocol
     March 26, 2013 - In quantitative analyses, we will consider performing subgroup analyses to assess the impact of each … Pairwise meta-analyses Direct pairwise meta-analyses will be undertaken when there are more than three … All meta-analyses will be based on random effects models. 29 Sensitivity analyses (including leave-one-out … analyses, analyses assuming a fixed effects model, and reanalyses after excluding a group of studies … How should meta-regression analyses be undertaken and interpreted?