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361. Disposition of Comments_Comparative Effectiveness Review No. 257_Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-disposition-comments.pdf
     June 28, 2022 - evaluating the impact of replacing routine antenatal visits with televisits provided demographic subgroup analyses … summarized the applicability in the Discussion and more explicitly highlighted the lack of subgroup analyses

362. Vitamin-D-Calcium-Protocol-130611 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
     September 13, 2013 - We will also assess the reporting of intention-to-treat analyses and crossovers when so designed, as … online: June 10, 2013 12 applicable), clear reporting of comparisons in the study, statistical analyses … It is not anticipated that new meta-analyses will be conducted, based on familiarity with the heterogeneity … Meta- regressions/sensitivity analyses and subgroup analyses are not anticipated, unless the TEP recommends

363. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
     December 14, 2010 - We will define loss to follow-up as the number of patients excluded from efficacy analyses, expressed … (Across a broad array of meta-analyses, an evaluation found that trials scoring 0-2 report exaggerated … For the efficacy and comparative effectiveness analyses, we will focus on studies that report outcomes … Since most of the scales used as outcome measures in the pooled analyses are scored so that more severely … All meta-analyses will be conducted with Stata statistical software, version 8.2 (Stata Corp., College

364. worker-health-protocol-150526 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
     May 26, 2015 - We plan to exclude studies deemed high risk of bias from our main data synthesis and main analyses for … KQ 2; we will include them only in sensitivity analyses. … Nonetheless, we will consider performing meta-analyses where we have at least three unique studies of … meta-analysis seems appropriate in these circumstances, we will perform only random-effects model meta-analyses … can be narrowed down to a small number of promising factors, we will consider these for subgroup analyses

365. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
     July 01, 2012 - review the relevant scientific literature on topics assigned to them by AHRQ and conduct additional analyses … identified to address the questions of risk reclassification or predicted performance in simulation analyses … aggressive and nonaggressive disease, and investigators should consider the possibility for subgroup analyses … Environmental and heritable factors in the causation of cancer--Analyses of cohorts of twins from Sweden … The Newcastle- Ottawa Scale (NOS) for assessing the quailty of nonrandomised studies in meta-analyses

366. Management of Suicidal Thoughts and Behaviors in Youth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
     February 05, 2025 - health disorders associated with suicide, such as major depressive disorder (MDD).19, 20 However, meta-analyses … • Comparative observational studies • Before—after studies • Relevant systematic reviews, or meta-analyses … To further explore heterogeneity, we plan to conduct preplanned subgroup analyses (listed in Table 1 … We will lower SOE grading when sensitivity analyses (1) show substantial difference in estimates derived … The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses

367. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
     April 01, 2020 - We performed stratified analyses to evaluate specific techniques within broader intervention categories … Data Analysis and Synthesis Meta-analyses from the 2018 report were updated and new analyses conducted … We performed additional sensitivity and subgroup analyses based on specific interventions (e.g., type … when poolable data were available, and conducting stratified and sensitivity analyses to evaluate … Some meta-analyses were based on two or three trials; findings based on such meta- analyses must be

368. Methods-Balancing-Harms-Benefits Research-2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
     January 01, 2012 - The fifth step consists of sensitivity analyses to explore the effects of changing the estimates or … In such cases, sensitivity analyses should take different weights into consideration. … (2) The type of analyses: Analyses for benefit harm assessment could include any type of statistical … Since none of the approaches are perfect and all require some assumptions, sensitivity analyses are … Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

369. Disposition of Comments for Imaging Tests for the Staging of Colorectal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
     November 20, 2014 - Most of the analyses were odds ratios of errors in staging—not bivariate models—which readily produces … We have redone the analyses using odds ratios for matched data since the same patients underwent both … We have provided the data on which the under and over staging analyses were based. … Statistical heterogeneity was discussed in the text for analyses where it was detected. … As a general rule, the authors of the studies did not perform any statistical analyses.

370. Cervical Degenerative Disease Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
     January 12, 2022 - Data Synthesis We will conduct meta-analyses of randomized trials and nonrandomized studies separately … pooling studies if there are at least two clinically and methodologically comparable studies.42,43 Meta-analyses … Sensitivity and subgroup analyses will be performed to explore statistical heterogeneity using the I2 … We will summarize within-study analyses of subgroup differences and perform study-level analyses on … Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised

371. Dietary-Supplements Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
     April 01, 2012 - Meta-analyses were carried out when there was clinical and methodological homogeneity. … Twenty-two studies contributed to meta-analyses in this review. … (See pooled analyses for HDL-C, LDL-C, total cholesterol, and triglycerides.) … Meta-analyses were possible for some omega-3 fatty acids studies. … Meta-analyses involving cross-over trials: methodological issues.

372. Cer-250-Cannabis-2024-Surv-Rep-Update-Tables-F1-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-tables-f1-2.xlsx
     January 01, 2024 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other

373. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
     April 01, 2020 - We synthesized the data qualitatively when quantitative analyses were not appropriate (e.g., due to … For bodies of evidence for which we could conduct sensitivity analyses, we based the final SOE grade … We appended a footnote to SOE tables to indicate when sensitivity analyses changed the SOE grade. … The full report appendices list all moderator analyses. … These subgroup analyses, when available, were generally hypothesis generating because studies were

374. Disposition of Comments Report for Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
     October 23, 2012 - studies did not specify that at least 80 percent of the study population had dementia and (2) that analyses … Our review sought to include RCTs, NonRCTs, systematic reviews, meta analyses, subgroup and or post-hoc … analyses, case-control studies, and prospective cohorts. … Did not seem to guide the analyses. … As to the analyses, the report does (for example) differentiate the effect of NH SCUs compared to AL

375. Digestible Carbohydrate Intake and Maternal-Infant Outcomes: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-protocol.pdf
     April 08, 2024 - and mode of nutritional assessment including supplement use matters,13 making data collection and analyses … will adhere to the international PRISMA45 (Preferred Reporting Items for Systematic reviews and Meta-Analyses … cohort studies • Nested case-control studies • Narrative reviews • Systematic reviews • Meta-analyses … studies if there are at least two clinically and methodologically comparable studies.46,56,57 Meta-analyses … We will assess statistical heterogeneity of sensitivity and subgroup analyses (e.g., differences by

376. Standardized Library of Asthma Outcome Measures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-asthma.pdf
     April 01, 2019 - review the relevant scientific literature on topics assigned to them by AHRQ and conduct additional analyses … ‘uncontrolled’ only) on the selected measurement instrument should be recorded to permit future analyses … ‘uncontrolled’ only) on the selected measurement instrument should be recorded to permit future analyses

377. Evidence Map on Home and Community Based Services (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-map-hcbs-protocol.pdf
     July 27, 2023 - We will use relevant systematic reviews and meta-analyses to identify additional existing and new literature … Question 1, we will include RCTs, comparative observational studies, and systematic reviews/meta-analyses … design • Guiding Question 1: o RCTs o Comparative observational studies o Systematic reviews or meta-analyses

378. Disposition of Comments for Self-Measured Blood Pressure Monitoring: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
     January 01, 2012 - “These summary estimates remained essentially unchanged in sensitivity meta-analyses that included … Those articles that were found by the search mechanism, but not included in the actual meta-analyses … “These summary estimates remained essentially unchanged in sensitivity meta-analyses that included … “These summary estimates remained essentially unchanged in sensitivity meta-analyses that included … In our literature update, we found a study (Bosoworth 2011, FU report on Bosworth 2009) with analyses

379. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
     July 18, 2011 - We will use the random effects model for all meta-analyses with Review Manager 5.0 software (The Cochrane … Reasons for heterogeneity will be explored through subgroup analyses and meta-regression (where there … Planned subgroup analyses include age, sex, race, duration of headaches, and nonresponders to treatment … Sensitivity analyses will be conducted to assess the robustness of the findings across study quality … The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses

380. Cer-250-Cannabis-2025-Surv-Rep-Update-Tables-F1-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-tables-f1-2.xlsx
     January 01, 2025 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other