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281. Antiplatelet-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
     September 01, 2013 - We performed sensitivity analyses assuming a recessive or additive model. … We used hazard or incidence rate ratios in our meta- analyses whenever available or extractable from … Generally, these analyses were congruent with analyses using a dominant model because they also indicated … to reconstruct such analyses from the reported data. … (All analyses assumed a dominant model for loss-of-function alleles; analyses under an alternative

282. Medical Care Journal Supplement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
     January 01, 2007 - Improving Depiction of Benefits and Harms: Analyses of Studies of Well-known Therapeutics and Review … Analyses With Observational Databases. Med Care. 2007;45(Suppl 2): S103–S107. S108 Matthew H.

283. Transparency of Reporting Requirements: Management of Infertility (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
     September 02, 2016 - studies identified there to published studies (to detect publication bias) and to compare planned analyses … arms • Intervention description • Study design • Outcomes measures • Analysis approach • Subgroup analyses … Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised … Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic … meta-analysis"[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta-analyses

284. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - We will define loss to follow-up as the number of patients excluded from efficacy analyses, expressed … (Across a broad array of meta-analyses, an evaluation found that trials scoring 0-2 report exaggerated … For the efficacy and comparative effectiveness analyses, we will focus on controlled trials that report … Since most of the scales used as outcome measures in the pooled analyses are scored so that more severely … All meta-analyses will be conducted with Stata statistical software, version 8.2 (Stata Corp., College

285. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
     January 01, 2005 - The above conclusion was based on three recent meta-analyses of randomized controlled trials comparing … These analyses had minimal bias and their results are considered valid (Grade A). … From 2 meta-analyses, PPIs reported more adverse events compared with H2RA or placebo; headache, diarrhea

286. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - We conducted pairwise meta-analyses, using the DerSimonian and Laird random- effects model. … Network meta- analyses were conducted using a Bayesian hierarchical model. … These findings are based on two published network meta-analyses (low SOE). … Our review, and two other reviews, conducted sensitivity analyses (two analyses, one including the … Efficacy of psychological therapy in schizophrenia: conclusions from meta- analyses.

287. Disposition of Comments for CER 161 Major Depressive Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder-disposition-160504.pdf
     December 08, 2015 - The data in our meta-analyses does demonstrate similar comparative effectiveness between SJW and SGA … However, we changed our SOE rating from moderate to low for the SJW analyses to reflect our concern … Additionally, we changed our SOE rating from moderate to low for the SJW analyses primarily due to … We viewed network meta-analyses (NWMA) as an additional analytic tool in cases where direct evidence … We examined this in sensitivity analyses and reported these analyses in the results.

288. Cannabis-App-G-Table-Surveillance-Report-2 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-g-table-surveillance-report-2_0.xlsx
     May 29, 2025 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other

289. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
     November 03, 2011 - c If we do conduct meta-analyses, we will include studies of any size. … We will not include poor-quality studies in our analyses. E. … We plan to stratify analyses and/or perform subgroup analyses when possible and appropriate. … These analyses will take place in the context of KQs 1 to 4. F. … If the data allow, we will perform subgroup analyses to explore the influence of specific factors (

290. Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
     September 02, 2016 - Empirical analyses of prospective registry data can inform on the time between study completion and … Analyses of studies included in the original review that also have a registry record For these studies … If meta-analyses are not conducted, we will assess whether the new studies fall within the range of … A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. … Also LOW risk of bias if any baseline differences were adjusted for in all relevant analyses.

291. Appendicitis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
     December 01, 2015 - We explored heterogeneity using subgroup and meta-regression analyses. … When studies reported results at multiple cutpoints, we performed analyses at low-risk and high- risk … The full report presents the results of sensitivity analyses for the test performance of imaging … For some important modalities that have been investigated to some extent in previous meta-analyses … Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement.

292. Microsoft Word - 3-DKE274__ACEI-ARB-DRI__Comments_Disposition_Table-21_Jan_2011 cyk _2_.docx (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
     October 07, 2011 - the most relevant reference for this section, but have updated reference #8 to reflect more recent analyses … Methods Several meta-analyses were conducted and reporting of these should all adhere to the PRISMA … potential for publication bias should be assessed and reported (likely in an Appendix) for all meta-analyses … General (clarity and usability) The forest plots of meta-analyses would be more usable if they were … However, several of our meta-analyses were done across very heterogeneous studies, and Peto's method

293. Research Protocol for Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
     October 02, 2018 - Data Extraction Each study with multiple publications or secondary analyses will be extracted together … We may conduct random effects model meta-analyses of comparative studies if at least three studies are … We will also explore the use of hierarchical (random intercept/random slope) meta-regression analyses … Sensitivity analyses will examine robustness of results to alternative prior distributions; attribute … The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses

294. Schedule of Visits and Use of Telemedicine for Routine Antenatal Care: A Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antenatal-care.pdf
     January 01, 2020 - All subgroup analyses or other evaluations of heterogeneity of treatment effect will be extracted. … In addition, we will assess the adequacy of analyses. … We do not expect to be able to conduct statistical analyses on these evaluations (i.e., meta- analysis … For meta-analyses of proportions, we will use Freeman-Tukey double arcsine transformations to account … We will preferentially summarize adjusted analyses.

295. Findings of Bayesian Mixed Treatment Comparison Meta-Analyses: Comparison and Exploration Using Real-World Trial Data and Simulation | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/bayesian-mixed-treatment/research

296. Disposition of Comments for CER 222: Achieving Health Equity in Preventive Services (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-222-health-equity-preventive-services-comments.pdf
     December 03, 2019 - various ethnic minority groups and other diverse populations and are especially interested in subgroup analyses … Julia Charles: Centers for Disease Control and Prevention Including studies and related analyses

297. Comparative Effectiveness of Medications in Patients with Epilepsy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
     March 01, 2012 - Peer Reviewer #2 Methods “Subgroup and Sensitivity Analyses” I would like to know why there were … no subgroup / sensitivity analyses done base upon study quality? … Given the large number of outcomes and the large number of subgroup and sensitivity analyses to be … Peer Reviewer #2 Methods “We also considered measures of heterogeneity from our meta- analyses in … The authors note that these subgroup analyses were not very informative.

298. Disposition of Comments Report for Evidence Report/Technology Assessment No. 214 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
     February 25, 2014 - group at follow-up (not at baseline), should be referenced, but should be excluded from the Meta-Analyses … assessment indicates, at a minimum, that the following evaluations should be removed from the Meta-Analyses … This could depend on whether the authors explicitly stated that they used this type of analyses, or … Studies that used intention-to-treat analyses were generally judged to have a low risk of bias for the … It is surprising that breastfeeding was not controlled for in the analyses or addressed in the report

299. Disposition of Comments Report for The Patient-Centered Medical Home (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
     July 03, 2012 - These analyses should be separate. … These analyses led to a change in conclusions for economic outcomes. … These analyses should be separate. We appreciate your raising this concern. … These analyses led to a change in conclusions for economic outcomes. … We conducted subgroup analyses to compare effects in adults and pediatric populations.

300. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - Reviews.13 The reporting complies with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses … Many of the included clinical trials did not report subgroup analyses, and often, the subgroups were … Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.