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201. Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
     January 01, 2017 - We carried out hand searches of the reference lists of recent systematic reviews or meta-analyses of … We also conducted analyses to estimate the effects of including high risk of bias studies in the analyses … These analyses suggested no systematic effects of these studies; thus, we retained them. … after sensitivity analyses showed that they had no systematic effects on outcomes. … final analyses (Table B).

202. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
     October 01, 2006 - Angioplasty and comparative studies that combined interventions for analyses Worse baseline kidney function … Most of the comparative studies, however, did not distinguish between interventions in these analyses … The studies were RAS severity heterogeneous in their analyses and their conclusions. 1 found a borderline … The studies were heterogeneous in their (continued) analyses and their conclusions. 2 found bilateral … Other interventions N/A • No study that met eligibility criteria reported analyses of whether other

203. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
     August 05, 2010 - Results from previously conducted meta-analyses and systematic reviews on these topics will be sought … that included unpublished data inaccessible to the public, but because the results of such analyses … We expect to conduct data synthesis similar to the analyses conducted for the original CER. … In the original CER, we performed two quantitative analyses. … Because only four trials were available for pooling, we did not attempt meta-regression analyses to

204. S89 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
     October 01, 2007 - Results: Using the new real-time surveillance system, ongoing analyses of meningococcal conjugate vaccine … Outcomes We identified outcomes of interest by reviewing data from several sources: analyses from VAERS … Already observed via passive surveillance, so that the current maxSPRT analyses would be hypothesis testing … For Guillain-Barre syndrome, we used a rate of 1.4 cases per 100,000 person-years based on analyses of … In age-stratified analyses, children age 11–12 years were administered the highest number of vaccinations

205. Version 2_Risk of Reinfection From SARS-CoV-2 -- An Update of an Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
     December 31, 2022 - We abstracted information from study-specific sensitivity analyses and regression analyses when available … Population and Methodological Factors Affecting the Risk of Reinfection We conducted analyses of six … Sensitivity Analyses Figure C-1. … Measuring inconsistency in meta-analyses. … Sensitivity Analyses Appendix D. Ongoing Studies Appendix E.

206. Diabetes-Behavior-Programs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_research-protocol.pdf
     June 05, 2014 - For reviews of T1DM or T2DM that conducted meta-analyses, the vast majority only evaluated HbA1c as … We will conduct multiple variable analyses and will investigate patient-important outcomes in addition … We anticipate that pairwise analyses will be used for Key Questions 1, 2, and 4. … Sensitivity analyses (including leave-one-out analyses, assuming a fixed effects model, re- analyses … How should meta-regression analyses be undertaken and interpreted? Stats Med. 2002;21(11):1559-73.

207. Measuring-Blood-Pressure Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
     January 01, 2012 - Sensitivity analyses were run excluding the quality C studies. … Meta-analyses revealed no significant effect at 2 months followup. … Meta-analyses showed statistical heterogeneity at 6 and 12 months. … The meta-analyses were statistically heterogeneous at 6 and 12 months. … • Subgroup analyses were reported by 4 trials.

208. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - In addition to an update of the analyses for each of the original key questions (modified to consider … We will also include reports of post hoc analyses and open-label extensions of trials. KQ3. … randomized controlled trials, systematic reviews).To identify additional systematic reviews and meta-analyses … The quality of meta-analyses will be assessed using aspects of internal and external validity as suggested … for comparisons for which we are able to identify three or more outcomes, we will conduct pooled analyses

209. Antipsychotics for the Prevention and Treatment of Delirium: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
     June 01, 2018 - We will conduct meta-analyses when there are sufficient data (at least three studies) and studies are … We will then stratify studies by medication and repeat the pooled analyses and measures of heterogeneity … model with the DerSimonian and Laird formula in settings of low heterogeneity23 or with appropriate analyses … formula for calculating between-study variance in settings of low heterogeneity23 or with appropriate analyses … Measuring inconsistency in meta- analyses.

210. Stroke Prevention in Atr ial Fibr illation Patients: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
     October 27, 2017 - If there are sufficient studies, we will perform subgroup analyses and/or meta-regression analyses to … Association between analytic strategy and estimates of treatment outcomes in meta-analyses. … The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta- analyses … • Systematic reviews, meta-analyses, or methods articles (used for background and • Because … component references only) • Systematic reviews, meta- analyses, or methods articles (used for

211. Renal Artery Stenosis Management Strategies: An Updated Comparative Effectiveness Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
     August 16, 2016 - analyses with propensity score matching. … Thank you TEP Reviewer #2 Methods The analyses performed seemed appropriate. … We have added this to the Subgroup and predictor analyses section. … and/or propensity score analyses may be reasonable alternatives. … There are also future CORAL analyses.

212. Covariate Selection for Observational Comparative Effectiveness Research
     effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
     January 01, 2013 - Statistical considerations Descriptive Statistics/Unadjusted Analyses Traditional Multiple Regression … Missingness can be characterized by using exploratory data analyses. … by using exploratory data analyses. … Consider the effect of missing data on analyses. … Sensitivity analyses can address residual confounding.

213. Disposition of Comments for Comparative Effectiveness Review 133 Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
     May 27, 2014 - My surprise stems from the fact that numerous meta-analyses of these trials have been conducted over … I see that you did meta-analyses with as few as two studies. … The statistical methods were appropriate for the analyses. … In meta-analyses, we have ordered trials by publication date. … However, single studies were also included in this appendix along with meta- analyses.

214. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
     September 21, 2012 - Their subgroup analyses would have had lower power, but the main study was appropriately powered for … Consequently, investigators should consider incorporating sensitivity analyses when calculating the … o Specify the expected precision (or statistical power) for any planned subgroup analyses. … the expected precision (or statistical power) in alternative special situations, as in sensitivity analyses

215. Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
     September 11, 2015 - review the relevant scientific literature on topics assigned to them by AHRQ and conduct additional analyses … For KQ 2, we searched for subgroup analyses reported by individual trials that focused on whether a … We first conducted subgroup analyses of the pairwise meta-analysis results for HbA1c for behavioral … programs compared with usual care and active controls at longest followup; subgroup analyses based … What contributions do languages other than English make on the results of meta-analyses?

216. Alcohol-Misuse Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
     April 28, 2010 - For Key Question 2, we focused on systematic reviews and meta-analyses, and we did not restrict the … We used subgroup analyses to explore whether results differed by intensity, sex, country, provider … Subgroup analyses did not identify differences between men and women. … We conducted sensitivity analyses to explore how NNT and NNS would change using other assumptions. … Measuring inconsistency in meta-analyses. BMJ. 2003 Sep 6; 327(7414):557-60.

217. Executive Summary_Comparative Effectiveness Review No. 252: Management of Infantile Epilepsies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
     October 01, 2022 - evidence on infants 1 month to less than 36 months, including a laborious search for pertinent subgroup analyses … evidence prior to 1999 (which may have excluded some relevant studies), sparse data which precluded analyses

218. The Magnitude of Small-Study Effects in the Cochrane Database of Systematic Reviews: an Empirical Study of Nearly 30 000 Meta-analyses | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/grant-manuscripts/cochrane-database-abstract

219. Evidence-Summary-CER-206-Sodium-And-Potassium-Intake-Effects-On-Chronic-Disease-Outcomes-And-Risk (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
     June 01, 2018 - The IOM Sodium Intake in Populations report listed “analyses examining the effects of dietary sodium … We did not take use of antihypertensive medications into account in our analyses of RCT data, primarily … Sensitivity analyses that omitted high- and unclear RoB studies did not appreciably alter consistency … Effect of lower sodium intake on health: systematic review and meta-analyses. … Effect of lower sodium intake on health: systematic review and meta-analyses.

220. Disposition of Comments Report for CER 134 Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
     May 13, 2014 - To explore this issue, we have added sensitivity analyses to the report that stratify studies that … them in sensitivity analyses.” … and Anton et. al. ) restricted their analyses to Caucasians. … We added the data sent by the commenter to the relevant analyses. … We added the data sent by the commenter to the relevant analyses.