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21. S58 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
    October 01, 2007 - For example, longitudinal analyses of antiretroviral medication use among Medicaid beneficiaries with … Supports detailed analyses of subgroups, rare conditions and comorbidities, including individuals with … Censoring and changes in diagnosis, treatment, and eligibility status complicate analyses. … Construction of eligibility timelines is used to select intervals to be included in analyses. … Descriptive analyses of the integrity of a US Medicaid claims database.

22. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
    June 16, 2010 - Rather, new analyses are needed. … Study-level and individual patient data meta-analyses. … Ongoing studies and interim analyses. Sources of Full text publications. … Accordingly, the tool will be applied to all meta-analyses. … A random effects model will be assumed for all meta-analyses.

23. Colorectal-Surgery-Preparation Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
    April 01, 2014 - We also performed sensitivity analyses, such as leave-one-out analyses, analyses assuming a fixed-effects … model, analyses including a retracted study, and analyses evaluating alternative network topologies … Fifty-eight studies were included in main analyses. … Forty-two of the 44 RCTs were included in main analyses. … Results were robust in all sensitivity analyses: use of informative priors, leave-one-out analyses,

24. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - Sensitivity Analyses Completing a CER is a structured process. … Studies with zero events in one arm should be included in the analyses. 3.2. … Sensitivity analyses 1. … This article does not address every major issue relevant to meta-analyses. … Measuring inconsistency in meta-analyses. BMJ 2003;327:557–560. 18 48.

25. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - Sensitivity Analyses Completing a CER is a structured process. … Studies with zero events in one arm should be included in the analyses. 3.2. … Sensitivity analyses 1. … This article does not address every major issue relevant to meta-analyses. … Measuring inconsistency in meta-analyses. BMJ 2003;327:557–560. 18 48.

26. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - We have clarified our approach to subgroup analyses, and mentioned that we conducted sensitivity analyses … for outcomes with at least three studies and network meta-analyses for two outcomes. … All analyses were conducted in a Bayesian framework. No response required. … Peer Reviewer 9 Methods It is fine to use Bayesian method to conduct pairwise meta-analyses. … All meta-analyses were random effects. TEP 10 Methods Yes to all.

27. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - We have clarified our approach to subgroup analyses, and mentioned that we conducted sensitivity analyses … for outcomes with at least three studies and network meta-analyses for two outcomes. … All analyses were conducted in a Bayesian framework. No response required. … Peer Reviewer 9 Methods It is fine to use Bayesian method to conduct pairwise meta-analyses. … All meta-analyses were random effects. TEP 10 Methods Yes to all.

28. Disposition of Comments_Comparative Effectiveness Review No. 265_Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
    August 29, 2023 - The Appendix also contains analyses based on last follow-up. … For meta-analyses looking at post-RT up to 4 weeks, if studies reported earlier time frames, we used … The report analyses, tables and plots are consistent with the protocol for answering the key questions … arms (i.e., non-comparative analyses). … These additional analyses would be beyond the scope of the protocol and raise methodological concerns

29. Disposition of Comments Report for Comparative Effectiveness Review 128 Oral Mechanical Bowel Preparation for Colorectal Surgery (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
    April 30, 2014 - , but not necessarily for the network analyses). … , including analyses not stratified by the use of enema. … We have added results from these analyses for all outcomes. … statistical analyses. … There is just too much information and too many analyses. Thank you.

30. Executive summary_Comparative Effectiveness Review No. 276: Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
    December 01, 2024 - Where there was sufficient evidence, we conducted random effects network and pairwise meta-analyses. … Network meta-analyses indicated that remote ERP is equivalent to in-person ERP for OCD symptoms and … We found 15 studies (2 RCTs and 13 single-arm studies) that reported multivariable analyses of predictors … Given the relatively sparse evidence within comparator-outcome categories, we did not perform subgroup analyses … , including non-white, low socioeconomic status children, and of sufficient size to allow subgroup analyses

31. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
    March 10, 2010 - We really wanted to conduct these analyses but as we discuss in KQ7, we cannot fully provide this data … We acknowledge We now specify which ACE inhibitors and ARBs were included in the different analyses … analyses, there is a complicated matrix of different analyses partitioned according to population, … We strongly suggest that the EPC eliminate those analyses in which studies of ACE inhibitors and ARBs … In our revised CER we now provide more insight into our rationale for conducting the analyses in this

32. Menopause-Protocol-130612 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
    June 12, 2013 - Other meta-analyses and systematic reviews will not be included. … insufficienta Meta-analyses/systematic reviews Include Observational studies Include if meta-analyses … Conducting Meta-Analyses in R with the metafor Package. … How should meta-regression analyses be undertaken and interpreted? … Baseline risk as predictor of treatment benefit: three clinical meta-re-analyses.

33. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
    January 01, 2012 - Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the … White Paper A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses …   Research White Paper A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses … Published frameworks or models designed to use results of systematic reviews or meta-analyses in new … Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

34. Choice-Of-Mean White-Paper (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
    April 01, 2015 - These meta-analyses included 5 to 13 studies and 218 to 4,100 patients (Table 2). … The other three meta-analyses compared sleepiness16 and depression18 variables. … These meta-analyses included 3 to 17 studies and 215 to 3,252 patients (Table 3). … These meta-analyses revealed no clear common characteristics. 8 Table 2. … Measuring inconsistency in meta-analyses. BMJ. 2003 Sep 6;327(7414):557-60.

35. Ch 11-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
    January 03, 2012 - Analyses are available that can be used to estimate a study result in the presence of an hypothesized … The chapter concludes with a checklist of key considerations for including sensitivity analyses in a … It is not intended to be a comprehensive guide to implementing sensitivity analyses. … Spreadsheets that facilitate the conduct of these sensitivity analyses are available. … Guidance Key Considerations Check Propose and describe planned sensitivity analyses

36. Disposition of Comments for CER 212 Nonsurgical Treatments for Urinary Incontinence in Women (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-212-urinary-incontinence-disposition-comments.pdf
    August 08, 2018 - We added in the text of the methods section of the report that "Analyses were performed separately … However, we have added better sections of subgroup analyses regarding urge vs. stress, which in part … However, we have added better sections of subgroup analyses regarding urge vs. stress, which in part … urge) or by participant mean age; and in sensitivity analyses (split-node analyses to compare the direct … Our primary analyses are intead based on categories of interventions.

37. Slide 1
    effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
    January 01, 2013 - expected confidence interval Specify the expected precision (or statistical power) for any subgroup analyses … Specify the expected precision (or statistical power) as sensitivity analyses in special situations … ; and specify the expected precision (or statistical power) as sensitivity analyses in special situations … Specify the expected precision (or statistical power) for any planned subgroup analyses. … Specify the expected precision (or statistical power) as sensitivity analyses in special situations.

38. Slide 1
    effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
    January 01, 2013 - Explanatory subgroup analysis Exploratory subgroup analyses are mainly done to identify subgroup hypotheses … Typically, exploratory subgroups are not prespecified; thus, exploratory analyses enjoy more flexibility … A major problem with these analyses is that it is extremely difficult to obtain the sampling properties … General Considerations for Subgroup Analyses General Considerations for Subgroup Analyses The study … It is important to ensure adequate statistical power for confirmatory subgroup analyses.

39. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-disposition-comments.pdf
    September 18, 2024 - analyzed data based on the presence of a given component, regardless of other components (e.g., the CBT analyses … Given education’s special status, we did not conduct targeted meta-analyses of all studies that utilized … American Psychological Association General We commend the comprehensive reporting of subgroup analyses … categorizing behavioral interventions and the attempt to classify these in order to conduct the analyses

40. Methods Guide for Medical Test Reviews - Editorial (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guide-editorial_methods.pdf
    July 01, 2012 - For example, the annual number of meta-analyses (a subset of systematic reviews) indexed by MEDLINE … Published in 1999, the QUORUM (Quality of Reporting of Meta-Analyses) guideline for reporting systematic … Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement … Quality of Reporting of Meta-analyses. Lancet 1999;354:1896-900. 3. … PRISMA: Transparent reporting of systematic reviews and meta-analyses.