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121. Usefulness of Economic Evaluation Data in Systematic Reviews of Evidence | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/economic-evaluation-data/research
     October 23, 2012 - Economic data of interest include information that contributes directly to cost-effectiveness analyses … to include economic data in a systematic review, it may be sufficient to review available economic analyses

122. Research and Surveillance Methods for Improving Medication Safety Using Administrative Claims Databases | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/medicine-safety-databases/abstract
     January 01, 2005 - We will conduct sensitivity analyses to refine the algorithms and will characterize the patients in each … use pattern after sensitivity analyses, by age and sex.

123. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/transparency-neuropathy/research
     July 28, 2017 - grade with and without ClinicalTrials.gov records for pain and quality of life, conducting sensitivity analyses … Conclusions Researchers conducting systematic reviews should account for reporting bias in their analyses

124. Guidance for the Conduct and Reporting of Modeling and Simulation Studies in the Context of Health Technology Assessment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
     October 01, 2016 - Sensitivity analyses (to assess the influence of model inputs) and stability analyses (to evaluate the … analyses using ordered bar charts). … the need to perform sensitivity and stability analyses. … In statistical analyses, account for heterogeneity. … Random-effects meta-analyses are not always conservative.

125. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
     September 01, 2011 - A clinical rationale for these decisions should be provided or separate analyses should be presented … We have revised our depression analyses, conducting separate analyses for augmention studies of tx … Patient heterogenity is an issue in most of our analyses. … Yet the computation of the overall effects in several of the meta-analyses, which may be one of the … Actually, we refrained from doing pooled analyses across, drugs in response to reviewers comments

126. Assessing the Risk of Bias in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-risk-of-bias.pdf
     December 01, 2017 - Previous Reviews • When using an existing systematic review in a new systematic review or subgroup analyses … Previous Reviews If you are using an existing systematic review in a new systematic review or subgroup analyses … Use Risk of Bias Assessments in Synthesizing Evidence (I) At stage 4, you conduct preplanned analyses … Consider and conduct, as appropriate, additional quantitative or qualitative sensitivity analyses or … When summarizing evidence, consider conducting sensitivity analyses to evaluate whether including studies

127. Attention Deficit Hyperactivity Disorder Medications and Risk of Serious Cardiovascular Disease in Children and Youth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-heart-disease-adults_research.pdf
     November 01, 2011 - Alternative Analyses Appendix L. … We also performed analyses to test other key study assumptions. … Alternative analyses, ADHD medication use, and serious cardiovascular disease Alternative Analyses, … Alternative Analyses Addressing Age These analyses were stratified by age 2-17 years and age 18-24 years … Alternative Analyses Excluding Children with Serious Psychiatric Illness These analyses excluded

128. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - As such, we have refrained from these analyses. … It had already been included in our analyses. … – e.g. modified ROC analyses – are generally rarely reported). … We used fixed effects analyses as sensitivity analyses. … In such cases we actually performed meta-analyses.

129. Reporting the Findings of Updated Systematic Reviews of Comparative Effectiveness: How Do Users Want To View New Information? | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/reporting-findings-updated-reviews/white-paper
     May 16, 2013 - preferably shown in graphic form), while at the same time having access to the entire set of data and the analyses … Yet whereas policymakers need access to the entire data set and analyses that comprise a systematic review

130. Disposition of Comments Report for CER 207 on PTSD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
     May 17, 2018 - We did not include any high risk of bias studies in our meta analyses or SOE gradings. … Peer Reviewer 1 Methods Why did this SR not include sensitivity analyses like the 2013 SR? … We have now indicated that STATA was used for all meta analyses. … This study did not report findings from such an analyses. … Peer Reviewer 1 General 3) not doing quantitative sensitivity analyses.

131. DRAFT - Prehospital Airway Management: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/prehospital-airway-management-draft-report.pdf
     November 01, 2020 - Controlled clinical trials (CCTs) were included as RCTs in meta-analyses. … Forest plots for the primary analyses are included in Appendix H. … below (forest plots for sensitivity analyses are included in Appendix I). … Sensitivity analyses resulted in similar findings (Appendix I-20 to I-25). … (when performed) and qualitative analyses are included.

132. DRAFT - Prehospital Airway Management: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-draft-report.pdf
     November 01, 2020 - Controlled clinical trials (CCTs) were included as RCTs in meta-analyses. … Forest plots for the primary analyses are included in Appendix H. … below (forest plots for sensitivity analyses are included in Appendix I). … Sensitivity analyses resulted in similar findings (Appendix I-20 to I-25). … (when performed) and qualitative analyses are included.

133. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
     July 01, 2012 - Summarizing results from major axis regressions or Bland-Altman analyses is probably informative. … Again, it is advisable to seek expert statistical help when considering such quantitative analyses, … An important piece of information gained from such analyses is the range of 9-11 values defined … The difference versus average analyses from each study are represented by three horizontal lines: a … Applying the right statistics: analyses of measurement studies.

134. PCA3 Testing for the Diagnosis and Management of Prostate Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/prostate-cancer-test/research-protocol
     October 14, 2011 - Systematic Reviews and Meta-Analyses The quality of included systematic reviews/meta-analyses will … (e.g., sensitivity or subgroup analyses); and assessment of bias across studies? … (e.g., sensitivity or subgroup analyses); and assessment of bias across studies? … Assuming that two unmatched analyses can be performed for PCA3 testing and a comparator, further analyses … What contributions do languages other than English make on the results of meta-analyses?

135. Blood-Clots-Hip-Knee-Surgery Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
     March 01, 2012 - as to compare results of our meta- analyses with previously published similar analyses. … Our results are similar to that of previous pooled analyses of patients with total hip and total knee … The results of previous meta- analyses are in general agreement with the findings of our comparative … In base case analyses, prolonged prophylaxis increases the occurrence of minor bleeding and surgical … Sensitivity Analyses: A “what if” analysis that helps determine the robustness of a study.

136. Disposition of Comments for Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis -- Update of a 2007 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
     March 01, 2012 - The quality of these meta-analyses could vary greatly. … Also what is the real value to include all these prior-meta-analyses while some earlier meta-analyses … We performed all the meta- analyses that we judged were appropriate based on the analyses conducted … additional trials not included in the prior analyses. … It did not do de novo meta-analyses when meta-analyses already existed.

137. Microsoft Word - ehcrr#2toCSI.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
     August 01, 2007 - Results were confirmed in propensity score analyses and instrumental variables estimation adjusting for … yielded no substantive changes relative to traditional multivariable Cox regression analyses. … In instrumental variable analyses, conventional APMs continued to be associated with greater risks of … Sensitivity analyses revealed that very large relative risks of 5 or greater would be needed linking … This is evidence that our analyses did not differentially adjust important confounding variables with

138. Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-update/final-report-update-2018
     July 16, 2018 - Eligibility for network meta-analyses required the following: (1) patients with early RA had not attempted … Network meta-analyses found higher ACR50 response for combination therapy of biologics plus MTX than … Qualitative synthesis and network meta-analyses suggest that the combination of MTX with TNF or non-TNF

139. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - 1 that reported subgroup analyses were included. … For vasomotor symptoms and quality-of-life outcomes, network meta-analyses formed the primary analyses … Finally, interpreting network and pairwise meta-analyses deserves comment. … In the pairwise meta-analyses, only direct randomized comparisons are included; the network analyses … Data extraction errors in meta-analyses that use standardized mean differences.

140. Since their introduction in 20xx, DES have been shown in clinical trials to decrease TLR (… (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
     January 01, 2010 - The resulting analyses will better inform national practice patterns overall and in important patient … We refer to these latter analyses as 6 and 12 month landmark analyses. … S ens itivity Analys es We conducted two sensitivity analyses. … P res pec ified Outc omes Death Prior analyses comparing survival in DES and BMS treated patients … Unadjusted and adjusted results from time-to-event analyses for prespecified endpoints.