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101. Findings of Bayesian Mixed Treatment Comparison Meta-Analyses: Comparison and Exploration Using Real-World Trial Data and Simulation | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/bayesian-mixed-treatment/research
     January 31, 2013 - Findings of Bayesian Mixed Treatment Comparison Meta-Analyses: Comparison and Exploration Using Real-World … with Bayesian MTC meta-analysis to explore heterogeneity; and (3) how findings of Bayesian MTC meta-analyses

102. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
     March 25, 2012 - Other meta-analyses and systematic reviews will not be included. … insufficienta Meta-analyses/systematic reviews Include Observational studies Include if meta-analyses … A proposed method of bias adjustment for meta- analyses of published observational studies. … Conducting meta-analyses in R with the metafor Package. J Stat Software 2010;36(3):1-48. 51. … Baseline risk as predictor of treatment benefit: three clinical meta-re-analyses.

103. Fibromyalgia Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
     January 01, 2015 - ) from RCTs, or pooled IPD RCT analyses. … All eight pooled analyses of patient-level RCT data were drug studies. … The lack of denominator values after baseline was common in both RCTs and pooled analyses. … Updating criteria to evaluate the credibility of subgroup analyses. BMJ. 2010;340:c117. … What contributions do languages other than English make on the results of meta-analyses?

104. Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
     January 31, 2023 - We added p value for the interaction between all subgroup analyses in Appendix J. … The findings were generated from subgroup analyses and suffer higher risk of bias. … We intended to include “sexual health” in the analyses without restrictions. … In the methods, we stated that “we were unable to conduct other prespecified subgroup analyses … to rate and their rating may be misleading because they are derived from subgroup analyses.

105. Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/appendicitis/research-protocol
     December 10, 2013 - In quantitative analyses, we will consider performing subgroup analyses to assess the impact of each … Main analyses will include all relevant studies. … All meta-analyses will be based on random effects models. 59 Sensitivity analyses (including leave-one-out … analyses, analyses assuming a fixed effects model, and reanalyses after excluding a group of studies … How should meta-regression analyses be undertaken and interpreted?

106. 04-E029-1 Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
     December 01, 2011 - review the relevant scientific literature on topics assigned to them by AHRQ and conduct additional analyses … Furthermore, many analyses or databases combine AS, WW, and noncurative interventions like primary ADT … in their analyses, making it impossible to ferret out issues specifically related to AS. … We required multivariable analyses adjusting for a minimum of age and tumor stage (if the analysis was … We included multivariable database analyses of predictors for the offer or acceptance of or adherence

107. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
     October 18, 2010 - Surrogate endpoints (such as delay in delivery) are therefore common and meta-analyses are used to assess … Additional subgroup analyses may be considered posthoc as deemed appropriate. … at high risk of bias; limiting meta-analyses to randomized trials only; and including studies in meta-analyses … Sensitivity analyses will take the form of subgroup analyses as described above. … In addition to the sensitivity analyses outlined above, we will conduct sensitivity analyses to explore

108. Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
     February 01, 2018 - Meta-analyses of safety data: a comparison of exact versus asymptotic methods. … ► Conduct sensitivity analyses acknowledging data adequacy. … ► Conduct sensitivity analyses with acknowledgement of the inadequacy of data. … Low-event-rate meta-analyses of clinical trials: implementing good practices. … Meta-analyses of safety data: a comparison of exact versus asymptotic methods.

109. S50 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
     October 01, 2007 - Its comprehensive measurement frame- work provides a basis for analyses of significant bivariate and … Conclusions: Outcomes improved when practices associated with better outcomes in PBE-CPI analyses were … Create a study database suitable for statistical analyses. 5. … Subsequently, the clinical teams helped with data analyses. … PSROP regression analyses produced 2 surprising con- sistent findings.

110. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - In quantitative analyses, we will consider performing subgroup analyses to assess the impact of each … Main analyses will include all relevant studies. … All meta-analyses will be based on random effects models.59 Sensitivity analyses (including leave-one-out … analyses, analyses assuming a fixed effects model, and reanalyses after excluding a group of studies … How should meta-regression analyses be undertaken and interpreted?

111. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - the risk of mortality, stroke, MACE, coronary dissection, and coronary perforation in the overall analyses … and analyses limited to good- quality trials. … on final health outcomes (effect of distal filter on target revascularization) was seen in overall analyses … and analyses limited to good-quality trials. … Conclusion #4 Given the inadequate power in overall analyses and lack of data, we could not definitively

112. Comparative Effectiveness and Safety: Emerging Methods - Part I | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/safety-emerging-methods/executive
     September 25, 2007 - Improving Depiction of Benefits and Harms: Analyses of Studies of Well-Known Therapeutics and Review … Improving Depiction of Benefits and Harms: Analyses of Studies of Well-known Therapeutics and Review … Using Inverse Probability-Weighted Estimators in Comparative Effectiveness Analyses With Observational … Analyses With Observational Databases. Med Care . 2007;45(Suppl 2): S103-S107.

113. Omega−3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
     August 01, 2016 - Observational studies must have reported multivariate analyses. … All observational studies reported multivariate analyses (this was an eligibility criterion). … ) analyses. … Twenty subgroup analyses by statin use were reported (1 with ALA, 19 with marine oil). … • Other n-3 FA analyses: o There is insufficient evidence comparing n-3 FA to each other.

114. Living Systematic Reviews: Practical Considerations for the Agency for Healthcare Research and Quality Evidence-based Practice Center Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/practical-considerations.pdf
     March 01, 2022 - review the relevant scientific literature on topics assigned to them by AHRQ and conduct additional analyses … We were able to rapidly identify important new studies, especially those that might add to meta-analyses … Continuous updating meta-analyses as new studies are incorporated into the report presents advantages … As the evidence base matures, we will need to consider how often to update the meta- analyses. … The decision to update the meta-analyses depends on the relative sample sizes and risk of bias of the

115. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
     July 01, 2009 - However, only a minority of multivariable analyses bear this out. … Among 11 comparisons that reported both univariable and multivariable analyses, 6 found statistically … In both univariable and multivariable analyses reported, no study or population factors were found to … However, the reported data suggest that only a small proportion of patients included in the analyses … However, the reported data suggest that only a small proportion of patients included in the analyses

116. Breast-Biopsy-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
     September 01, 2014 - For this reason we refrained from performing meta-analyses for these outcomes. … Meta-regression analyses were possible for the following factors: needle gauge, choice of reference … Overall, within-study analyses and meta-regression analyses were insufficient to confirm (or exclude … Contextualizing the Results of Test Performance Meta-Analyses To contextualize the results of the … Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

117. Colorectal-Surgery-Preparation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
     March 26, 2013 - In quantitative analyses, we will consider performing subgroup analyses to assess the impact of each … Pairwise meta-analyses Direct pairwise meta-analyses will be undertaken when there are more than three … All meta-analyses will be based on random effects models.29 Sensitivity analyses (including leave- one-out … analyses, analyses assuming a fixed effects model, and reanalyses after excluding a group of studies … How should meta-regression analyses be undertaken and interpreted?

118. Template for Draft Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_appendixes.pdf
     October 06, 2006 - Not RCT Appendix C: Additional Analyses and Evidence Tables Appendix C: Additional Analyses … C-2 Appendix C: Additional Analyses and Evidence Tables (continued) Appendix Table 2. … C-4 Appendix C: Additional Analyses and Evidence Tables (continued) Appendix Table 3. … Appendix C: Additional Analyses and Evidence Tables (continued) Appendix Table 10. … C-27 Appendix C: Additional Analyses and Evidence Tables (continued) Appendix Table 14.

119. Impact of Contacting Study Authors on Systematic Review Conclusions: Diagnostic Tests for Hepatic Fibrosis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hepatic-fibrosis/white-paper
     April 02, 2014 - general, inclusion of the additional 29 studies had only minor effects on the diagnostic accuracy meta-analyses … provide 2 × 2 tables within the published manuscript for transparency and to facilitate additional analyses

120. Ventricular Arrhythmias and Cerebrovascular Events in the Elderly Using Conventional and Atypical Antipsychotic Medications | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antipsychotic-medicine-cardiovascular-elderly/research
     March 18, 2009 - groups (e.g., dementia, delirium) may themselves be risk factors for these outcomes so we restricted analyses … We also restricted analyses to just new users to guard against selection bias among prevalent users from … All confirmatory analyses were limited to outcomes found to be significant in the primary analysis. … Confirmatory analyses using propensity score adjustments 14 yielded nearly identical results to the … traditional multivariable Cox analyses.