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1. Development and Implementation of Secure Statistical Analyses on Distributed Databases | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/dsitributed-database-analyses/abstract

2. Horizon Scanning_Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
   January 01, 2015 - Horizon Scanning_Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports AHRQ … Healthcare Horizon Scanning System Report of a Pilot Project: Rapid Cost Analyses of Selected Potential … Report of a Pilot Project: Rapid Cost Analyses of Selected Potential High Impact Intervention Reports … We welcome comments on this report on the rapid cost analyses. … In 2014, AHRQ requested exploratory, rapid, cost analyses to elucidate the potential 1-year spend of

3. Disposition of Comments for CER 225: Substance Abuse Disorders in Adolescents (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-comments.pdf
   May 21, 2020 - • The draft results section was reported extensive detailed results of all analyses done. … only and removing complementary sensitivity analyses. 4) reduced the number of tables reporting … We 1) performed additional pairwise analyses (using restricted maximum likelihood estimation and … TAU and report these analyses along with with network meta-analyses. 2) reported results of network … meta-analyses of non-brief interventions with the added the proviso that these networks were very

4. Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
   January 01, 2013 - Separate Meta-Analyses Versus Joint Analyses Accounting for Within-Study Correlations .............. … Separate Meta-Analyses Versus Joint Analyses Not Accounting for Within-Study Correlations .......... … meta-analyses is at best modest. … Separate Meta-Analyses Versus Joint Analyses Not Accounting for Within-Study Correlations As shown … SDDiff or SEDiff Analyses in the 11 paired studies Separate meta-analyses of the two tests

5. Machine-Learning-Tools-Appendix-D (xls file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-appendix-d.xlsx
   January 01, 2024 - Mistral are promising for extracting numerical findings from trial reports to produce automated meta-analyses … Mistral are promising for extracting numerical findings from trial reports to produce automated meta-analyses … Automatic extraction of quantitative data from ClinicalTrials.gov to conduct meta-analyses 2019 ExaCT … Artificial Intelligence to Automate Network Meta‑Analyses: Four Case Studies to Evaluate the Potential … Automatic extraction of quantitative data from ClinicalTrials.gov to conduct meta-analyses 2019 ExaCT

6. Quantitative Synthesis: Learning Objectives and Recommendations (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-learning-objectives-recommendations.pdf
   July 01, 2019 - Outcome reporting bias: a pervasive problem in published meta-analyses. … Chapter 10: Analysing data and undertaking meta-analyses. … Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-60. … Chapter 10: Analysing data and undertaking meta-analyses. … How should meta‐ regression analyses be undertaken and interpreted?

7. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
   September 01, 2013 - , and decision or economic analyses. … The same resource levels apply to meta-analyses of mixed treatment comparisons (network meta-analyses … Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy. … Arcsine test for publication bias in meta- analyses with binary outcomes. … Does blinding of readers affect the results of meta-analyses?

8. Quantitative Synthesis: Chapter 4. Quantifying, Testing, and Exploring Statistical Heterogeneity (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-4.pdf
   July 01, 2019 - Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-60. … Chapter 10: Analysing data and undertaking meta-analyses. … Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-60. … Chapter 10: Analysing data and undertaking meta-analyses. … How should meta‐ regression analyses be undertaken and interpreted?

9. Quantitative Synthesis: Chapter 1. Decision To Combine Trials (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-1.pdf
   July 01, 2019 - Outcome reporting bias: a pervasive problem in published meta-analyses. … Chapter 10: Analysing data and undertaking meta-analyses. … Chapter 10: Analysing data and undertaking meta-analyses. … Outcome reporting bias: a pervasive problem in published meta-analyses. … Chapter 10: Analysing data and undertaking meta-analyses.

10. Defining an Optimal Format for Presenting Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
    January 01, 2019 - and VOI analyses). … (meta- analyses). … = cost-utility analyses. … being more common among meta- analyses and VOI analyses and less common among cost-effectiveness analyses … , cost-effectiveness/utility analyses, and value of information analyses.

11. White Paper_Supplementing Systematic Review Findings With Healthcare System Data: Pilot Projects From the Agency for Healthcare Research and Quality Evidence-based Practice Center Program (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/pilot-projects-supplementing-white-paper.pdf
    December 01, 2024 - Key Findings • While analyses of electronic health record (EHR) data may fill clinical evidence gaps … • Conducting supplemental data analyses is feasible but required substantial additional total hours … • Single health system datasets may be too small for subgroup analyses, and use of larger, national … EPCs also tracked additional resources needed to conduct supplemental analyses. … • What resources (time and expertise) are needed to conduct such supplemental data analyses?

12. Ch 3-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - Numerous subgroup analyses were conducted, most of which indicated relatively consistent effects of … Findings from such unfocused, exploratory subgroup analyses should be interpreted with caution even … Compared to confirmatory and descriptive HTE analyses, exploratory analyses enjoy more flexibility … - If confirmatory analyses, do power calculations. … Statistics in medicine – reporting of subgroup analyses in clinical trials.

13. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - and binary analyses of relative measures (odds ratio or relative risk). … • The additional power may not be necessary for many meta-analyses. … The exploratory nature of these analyses should be clear. … Sensitivity analyses Specify what sensitivity analyses are being done and how they relate to key … analyses undertaken. 15 References 1.

14. Slide 1
    effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
    January 01, 2013 - This presentation will: Propose and describe planned sensitivity analyses Describe important subpopulations … When results of analyses are consistent or unchanged by testing variations on underlying assumptions, … When the results of analyses are consistent or unchanged by testing variations on underlying assumptions … Sensitivity analyses can allow the investigator to quantify the effect that an unmeasured confounding … Presentation of Sensitivity Analyses Tabular The classic approach to presenting sensitivity analyses

15. Web Interactive Presentation of EPC Reports: A Foray Into Interactive Reports (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-web-interactive-presentation.pdf
    September 01, 2019 - In its current form, the tool does not provide or allow for additional analyses not included in the … First, there is a need to perform analyses, including sensitivity analyses, dynamically. … This can be accomplished by embedding statistical analyses in the interactive report. … We submit that, perhaps, the advantages of offering dynamic analyses outweigh their risks. … Conducting meta-analyses in R with the metafor package. J Stat Softw. 2010;36(3). 6.

16. Comparative Effectiveness Review Disposition of Comments Report: Anxiety in Children (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
    August 31, 2017 - We understand the importance of subgroup analyses. … In this revision, we added some subgroup analyses. … The subgroup analyses examined disorder specific studies. … Some studies appear to be missing in the analyses. … Our concerns regarding these analyses are twofold.

17. Methods Guide for Medical Test Reviews (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
    July 01, 2012 - Multivariate meta-analyses require advanced hierarchical modeling. … in a large empirical exploration of 308 meta-analyses.40 Chappell et al. argued that in meta-analyses … or subgroup analyses. … Guidelines for meta-analyses evaluating diagnostic tests. … When are summary ROC curves appropriate for diagnostic meta-analyses?

18. Future Research Needs for Treatment of Obstructive Sleep Apnea (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
    February 01, 2012 - Analyses of CPAP stratified by disease severity b. … Analyses of CPAP stratified by disease severity b. … and subgroup analyses. … Analyses of CPAP stratified by disease severity b. … or post hoc analyses of existing trials.

19. AHRQ Slide Template 2009 (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/reporting.ppt
    September 01, 2009 - Describe the methods of additional analyses (e.g., sensitivity or subgroup analyses, meta-regression … Example: Sensitivity analyses were pre-specified. … PMID: 20704038 Results: Additional Sensitivity Analyses Give the results of additional analyses, … Results: Additional Sensitivity Analyses Authors should report sensitivity analyses, which is usually … Results: Additional Subgroup Analyses It is important to separate subgroup analyses, which is usually

20. Cer-242-Radiation-Therapy-Brain-Metastases-Evidence-Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
    June 01, 2021 - comparators, and outcome measures and reporting, the number of studies that could be combined for analyses … Random effects meta-analyses computed hazard ratios (HRs), relative risks (RRs), and standardized mean … studies used mixed samples in terms of primary tumor type and prognosis, only WBRT studies allowed analyses … at all, and analyses were only possible for selected outcomes. … Despite the large number of identified research studies, analyses were limited as studies evaluated