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1. Allergy Disease | Digital Healthcare Research
   digital.ahrq.gov/medical-condition/allergy
   January 01, 2024 - Allergy Disease Understanding the patient experience of drug reaction … J Allergy Clin Immunol Pract. 2019 Jan;7(1):103-111. doi: 10.1016/j.jaip.2018.06.010. … Front allergy. 2022 May 10;3:904923. doi: 10.3389/falgy.2022.904923. … Electronic Health Record The use of electronic health records to study drug-induced hypersensitivity … The use of electronic health records to study drug-induced hypersensitivity reactions from 2000 to 2021

2. Encoding and Processing Patient Allergy Information in EHRs | Digital Healthcare Research
   digital.ahrq.gov/ahrq-funded-projects/encoding-and-processing-patient-allergy-information-ehrs
   January 01, 2024 - For some people, allergic reactions can be severe and even fatal. … Clinicians routinely elicit allergy information during the medical interview; however, allergies are … and compare the extracted allergies with those in patients’ structured allergy lists. … Finally, data from the NLP module were used to describe the epidemiology of drug allergies, food allergies … , and allergic reactions using longitudinal EHR data.

3. Improving Allergy Documentation and Clinical Decision Support in the Electronic Health Record | Digital Healthcare Research
   digital.ahrq.gov/ahrq-funded-projects/improving-allergy-documentation-and-clinical-decision-support-electronic-health
   January 01, 2024 - implemented a real-time EHR clinical decision support tool that uses picklists to rank the most likely allergic … reactions to a given allergen, comprehensive tools to support real-time allergy reconciliation, and … The use of electronic health records to study drug-induced hypersensitivity reactions from 2000 to 2021 … Vancomycin hypersensitivity reactions documented in electronic health records. … Quality of documentation of contrast agent allergies in electronic health records.

4. Encoding and Processing Patient Allergy Information in EHRs - Final Report (pdf file)
   digital.ahrq.gov/sites/default/files/docs/citation/r01hs022728-zhou-final-report-2018.pdf
   January 01, 2018 - fever, atopic eczema), and for some, allergic reactions can be severe or even fatal. … and allergic reactions. … reaction terms composed of 92% of all reactions stored in PEAR, sorted by frequency. … food allergies, and allergic reactions using longitudinal electronic health record data. … Allergic reactions included a high proportion (38.2%) of non-immune mediated opioid reactions (e.g

5. Allergy entry and deletion in the electronic health record. | Digital Healthcare Research
   digital.ahrq.gov/ahrq-funded-projects/encoding-and-processing-patient-allergy-information-ehrs/citation/allergy
   January 01, 2023 - Allergy entry and deletion in the electronic health record. … Allergy entry and deletion in the electronic health record. … Ann Allergy Asthma Immunol 2017 Mar;118(3):380-1. PMID: 28126435. … Principal Investigator Zhou, Li Project Name Encoding and Processing Patient Allergy … Document Type Journal Publication Population Patient Medical Condition Allergy

6. Improving Allergy Documentation and Clinical Decision Support in the Electronic Health Record (EHR) - Final Report (pdf file)
   digital.ahrq.gov/sites/default/files/docs/citation/r01hs025375-zhou-final-report-2022.pdf
   January 01, 2022 - To develop a comprehensive reaction value set, we studied drug hypersensitivity and contrast agent allergic … reactions documented in the EHR (Wong 2019, Deng 2019). … For contrast agent allergic reactions (Deng 2019), we determined the frequency of contrast agent allergens … For contrast agent allergic reactions, descriptive statistics were used to summarize patient characteristics … Development and validation of a deep learning model for detection of allergic reactions using safety

7. Vancomycin hypersensitivity reactions documented in electronic health records. | Digital Healthcare Research
   digital.ahrq.gov/ahrq-funded-projects/improving-allergy-documentation-and-clinical-decision-support-electronic-health/citation/vancomycin
   January 01, 2023 - Vancomycin hypersensitivity reactions documented in electronic health records. … Vancomycin hypersensitivity reactions documented in electronic health records. … J Allergy Clin Immunol Pract. 2021 Feb;9(2):906-912. doi: 10.1016/j.jaip.2020.09.027. … pubmed.ncbi.nlm.nih.gov/33011300/ Principal Investigator Zhou, Li Project Name Improving Allergy … Document Type Journal Publication Population Adults Medical Condition Allergy

8. Drug hypersensitivity reactions documented in electronic health records within a large health system. | Digital Healthcare Research
   digital.ahrq.gov/ahrq-funded-projects/encoding-and-processing-patient-allergy-information-ehrs/citation/drug-hypersensitivity
   January 01, 2023 - Drug hypersensitivity reactions documented in electronic health records within a large health system. … Drug hypersensitivity reactions documented in electronic health records within a large health system. … J Allergy Clin Immunol Pract. 2018 Dec 1. pii:S2213-2198(18)30751-7. doi: 10.1016/j.jaip.2018.11.023. … Principal Investigator Zhou, Li Project Name Encoding and Processing Patient Allergy … Language Processing System Document Type Journal Publication Medical Condition Allergy

9. The use of electronic health records to study drug-induced hypersensitivity reactions from 2000 to 2021: A systematic review. | Digital Healthcare Research
   digital.ahrq.gov/ahrq-funded-projects/improving-allergy-documentation-and-clinical-decision-support-electronic-health/citation/health
   January 01, 2023 - The use of electronic health records to study drug-induced hypersensitivity reactions from 2000 to 2021 … The use of electronic health records to study drug-induced hypersensitivity reactions from 2000 to 2021 … Immunol Allergy Clin North Am. 2022 May;42(2):453-497. doi: 10.1016/j.iac.2022.01.004. … pubmed.ncbi.nlm.nih.gov/35469629/ Principal Investigator Zhou, Li Project Name Improving Allergy … Document Type Journal Publication Population Researcher Medical Condition Allergy

10. Prevalence of food allergies and intolerances documented in electronic health records. | Digital Healthcare Research
    digital.ahrq.gov/ahrq-funded-projects/encoding-and-processing-patient-allergy-information-ehrs/citation/prevalence
    January 01, 2023 - Prevalence of food allergies and intolerances documented in electronic health records. … Prevalence of food allergies and intolerances documented in electronic health records. … J Allergy Clin Immunol 2017 May 23. pii:S0091-6749(17)30672-3. PMID: 28577971. … Principal Investigator Zhou, Li Project Name Encoding and Processing Patient Allergy … Language Processing System Document Type Journal Publication Medical Condition Allergy

11. ESP-VAERS Case Identification and Reporting Protocol (pdf file)
    digital.ahrq.gov/sites/default/files/docs/resource/Lazarus_ESP_VAERS_algorithm_v1_2007_11_05_1.pdf
    January 01, 2007 - 12 months Two RotaTeq Myocarditis 429.0, 422* Same code within past 12 months Two RotaTeq Hypersensitivity … – drug, unspec 995.20 None Three Pneumonitis – hypersensitivity 495.9 None Three Upper respiratory … tract hypersensitivity reaction 478.8 None Three Poisoning – bacterial vaccine 978.8 None Three … Three Benadryl Same medication (any dose) within the past 12 months Three Epinephrine None Three Allergies … * Allergy list prior to vaccine Three RotaTeq RotaTeq Allergy list prior to vaccine Three Rota* Allergy

12. Adverse and hypersensitivity reactions to prescription nonsteroidal anti-inflammatory agents in a large health care system. | Digital Healthcare Research
    digital.ahrq.gov/ahrq-funded-projects/encoding-and-processing-patient-allergy-information-ehrs/citation/adverse-and
    January 01, 2023 - Adverse and hypersensitivity reactions to prescription nonsteroidal anti-inflammatory agents in a large … Adverse and hypersensitivity reactions to prescription nonsteroidal anti-inflammatory agents in a large … J Allergy Clin Immunol Pract 2017 May -Jun;5(3):737-43. PMID: 28110055. … Principal Investigator Zhou, Li Project Name Encoding and Processing Patient Allergy

13. Weingart SN et al. 2003 "Physicians' decisions to override computerized drug alerts in primary care." | Digital Healthcare Research
    digital.ahrq.gov/health-it-tools-and-resources/workflow-assessment-health-it-toolkit/research/weingart-sn-et-al-2003
    January 01, 2003 - officer (odds ratio [OR], 0.26; 95% confidence interval [CI], 0.08-0.84) and if the patient had many drug allergies … drug allergies and intolerances that was entered by nurses, physicians, and pharmacists in the inpatient … "Physicians overrode the analgesic allergy alert in 13 of 14 cases. … "Physicians overrode only 7 of 17 antibiotic allergy alerts. … were less likely to prescribe (override) an alerted medication if the patient had multiple medication allergies

14. National Institute of Allergy and Infectious Disease | Digital Healthcare Research
    digital.ahrq.gov/organization/national-institute-allergy-and-infectious-disease
    January 01, 2023 - National Institute of Allergy and Infectious Disease Asthma Measurement

15. Kuperman GJ et al. 2007 "Medication-related clinical decision support in computerized provider order entry systems: a review." | Digital Healthcare Research
    digital.ahrq.gov/health-it-tools-and-resources/workflow-assessment-health-it-toolkit/research/kuperman-gj-et-al-2007
    January 01, 2007 - Workflow-Related Findings "Excessive drug-allergy alerting in clinically irrelevant circumstances … "In one study, physicians accepted less than 20% of drug-allergy alerts. … "Drug-allergy checking is inconsistent across CPOE applications and major shortcomings plague many drug-allergy … For example, some applications do not require structured, coded entry of allergens and allergic reactions … Drug-allergy checking then becomes close to impossible....

16. Methods for identifying and reconciling allergy information in the electronic health record. | Digital Healthcare Research
    digital.ahrq.gov/ahrq-funded-projects/improving-allergy-documentation-and-clinical-decision-support-electronic-health/citation/methods
    January 01, 2023 - Methods for identifying and reconciling allergy information in the electronic health record. … Methods for identifying and reconciling allergy information in the electronic health record. … Journal of Allergy and Clinical Immunology. 2021 Feb 1;147(2):AB168. https://doi.org/10.1016/j.jaci.2020.12.597 … fulltext#relatedArticl… Principal Investigator Zhou, Li Project Name Improving Allergy … Language Processing System Document Type Conference Proceeding Medical Condition Allergy

17. Expanding the reaction picklist in electronic health records improves allergy documentation. | Digital Healthcare Research
    digital.ahrq.gov/ahrq-funded-projects/improving-allergy-documentation-and-clinical-decision-support-electronic-health/citation/expanding
    January 01, 2023 - Expanding the reaction picklist in electronic health records improves allergy documentation. … Expanding the reaction picklist in electronic health records improves allergy documentation. … J Allergy Clin Immunol Pract. 2022 Oct;10(10):2768-2771.e2. doi: 10.1016/j.jaip.2022.06.046. … pubmed.ncbi.nlm.nih.gov/35835388/ Principal Investigator Zhou, Li Project Name Improving Allergy … Journal Publication Population Clinical Staff/Clinician Medical Condition Allergy

18. Towards improved drug allergy alerts: multidisciplinary expert recommendations. | Digital Healthcare Research
    digital.ahrq.gov/ahrq-funded-projects/encoding-and-processing-patient-allergy-information-ehrs/citation/towards
    January 01, 2023 - Towards improved drug allergy alerts: multidisciplinary expert recommendations. … Towards improved drug allergy alerts: multidisciplinary expert recommendations. … Principal Investigator Zhou, Li Project Name Encoding and Processing Patient Allergy … Provider Order Entry System Document Type Journal Publication Medical Condition Allergy

19. Food entries in a large allergy data repository. | Digital Healthcare Research
    digital.ahrq.gov/ahrq-funded-projects/encoding-and-processing-patient-allergy-information-ehrs/citation/food
    January 01, 2023 - Food entries in a large allergy data repository. … Food entries in a large allergy data repository. J Am Med Inform Assoc 2016 Apr;23(e1):e79-87. … Principal Investigator Zhou, Li Project Name Encoding and Processing Patient Allergy … Language Processing System Document Type Journal Publication Medical Condition Allergy

20. Quality of documentation of contrast agent allergies in electronic health records. | Digital Healthcare Research
    digital.ahrq.gov/ahrq-funded-projects/improving-allergy-documentation-and-clinical-decision-support-electronic-health/citation/quality
    January 01, 2023 - Quality of documentation of contrast agent allergies in electronic health records. … Quality of documentation of contrast agent allergies in electronic health records. … www.ncbi.nlm.nih.gov/pubmed/30846398 Principal Investigator Zhou, Li Project Name Improving Allergy … Language Processing System Document Type Journal Publication Medical Condition Allergy