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Showing results for "adverse events".
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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/hWzpnYXDpQzUr8U_5xY6qS
    January 01, 2003 - As a result, individuals with higher absolute risk for experiencing future adverse cardiovascular events … cardiovascular events. … Potential adverse effects of drugs—some sufficiently bothersome to interfere with adherence to the medica … - tion regimen—are common, but serious adverse drug reactions are rare. … Physicians should take adverse ef- fects into consideration when deciding whether to treat and which
  2. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
    November 24, 2020 - Adverse events were rare, with generally no group differences in serious adverse events, any adverseevents, hospitalizations, musculoskeletal injuries, or withdrawals due to adverse events. … events or no serious adverse events, 55 , 87 , 97 , 118 , 148 , 152 , 247 and other trials reported … 1 or more of the following: serious adverse events, any adverse events, hospitalizations, musculoskeletal … significant differences in any study for serious adverse events, any adverse events, hospitalizations
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/KFZpoMBYuoo8TRW6nhRev8
    October 23, 2023 - health outcomes Adverse events Event-driven vs daily oral PrEPb ADAPT/HPTN 067 Bekker et al,12 2018 … Clinical health outcomes Adverse events Long-acting injectable cabotegravir vs daily oral TDF/FTC … All adverse events were grade 1 except in 1 patient with grade 2 symptoms. … events or grade 3 or higher adverse events (Table 2; eTables 1-4 in the Supplement).6,7 There were also … adverse events, or STIs.
  4. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
    April 25, 2024 - the comparative performance and agreement between PREVENT (Predicting Risk of cardiovascular disease EVENTs … addition to other risk factors (KQs 1, 3 only) KQs 4, 5: Interventions aimed at preventing CVD events … placebo Models predicting mortality only or heart failure only Outcomes KQs 1, 4: CVD events … (e.g., myocardial infarction, stroke) and mortality KQ1a: In trials also reporting CVD events, the … , agreement between observed and predicted risks), and decision curve analysis KQs 3, 5: Serious adverse
  5. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - men and 6% for women. 1 Severe OSA is associated with increased all-cause mortality. 2 , 3 Other adverse … In general, mild OSA is defined as 5 to 15 events per hour, moderate OSA as 16 to 30 events per hour, … alternative therapy to positive airway pressure for patients with OSA who prefer them or for those with adverse … to the increase in prevalence of obesity. 1 , 2 Obstructive sleep apnea is associated with multiple adverse … , mucosal erosions, and jaw or temporomandibular joint pain or discomfort. 15 , 16 In general, the adverse
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
    August 23, 2022 - Statin therapy was not significantly associated with increased risk of serious adverse events (RR, 0.97 … to 1.26%]) (eFigure 9 in the  JAMA  Supplement), serious adverse events (10 trials, n = 55,419; RR, … events, serious adverse events, cancer, or elevated liver enzyme levels vs placebo or no statin therapy … events or muscle symptoms, these findings could be due to expectations regarding adverse effects and … Statin safety and associated adverse events: a scientific statement from the American Heart Association
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - Adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular … men and 6% for women. 1 Severe OSA is associated with increased all-cause mortality. 2 , 3 Other adverse … In general, mild OSA is defined as 5 to 15 events per hour, moderate OSA as 16 to 30 events per hour, … to the increase in prevalence of obesity. 1 , 2 Obstructive sleep apnea is associated with multiple adverse … , mucosal erosions, and jaw or temporomandibular joint pain or discomfort. 15 , 16 In general, the adverse
  8. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-viii-standardization-outcome-tables
    July 01, 2017 - Adverse events/states.
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/efwy72cuMdhcF2jotkhTzC
    March 29, 2019 - , 78 weeks) reported rates of neuropsychiatric adverse events among participants taking efavirenz; 29.6% … - atric adverse events, 3.3% (95% CI, 2.2%-4.3%) had depression, and 0.6% (95% CI, 0.2%-1.1%) had suicidal … ideation.46 However, an analysis of the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) … Comparative safety and neuropsychiatric adverse events associated with efavirenz use in first-line antiretroviral … Events of Anti-HIV Drugs study.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
    January 14, 2025 - Compared with placebo, no statistically significant associations were observed for adverse events. … events, serious adverse events, or gastrointestinal adverse events are shown in Figure 4 . … events and serious adverse events and moderate for no effect on upper gastrointestinal adverse events … for bisphosphonates and low for increased upper gastrointestinal adverse events for denosumab. … KQ5: Harms of treatment Bisphosphonates Discontinuations due to adverse events 27
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/falls-prevention-community-dwelling-older-adults-interventions
    July 21, 2022 - interventions to prevent falls in unselected or increased-risk community-dwelling older adults result in any adverse … Get Up & Go Test, 6-meter timed walk, Functional Reach Test, and Berg Balance Scale) KQ 2: Minor adverseevents that are reported using nonvalidated and nongeneralizable measures Followup Minimum
  12. www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002
    January 01, 2002 - Enteric-coated or buffered preparations do not clearly reduce adverse gastrointestinal effects of aspirin … Most events occur in older people and those with recognized risk factors for cardiovascular disease, … physicians and patients balance the reduced rate of nonfatal myocardial infarction against potential adverse … Aspirin for the primary prevention of cardiovascular events: recommendations and rationale. … Aspirin for the primary prevention of cardiovascular events: A summary of the evidence for the U.S.
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/xt2Uhv4qyLUZ8o2HB_a4YQ
    July 01, 2013 - events; however, many of these events are transient or self-limited, and ef- fective alternatives can … events, including meta- bolic disturbances associated with an increased risk for car- diovascular events … However, the early treatment group in the HPTN 052 study had ART-related adverse events more frequently … The 2005 USPSTF review included results from the large, ongoing DAD (Data Collection on Adverse Events … Common adverse effects of antiretroviral therapy for HIV disease.
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-for-prediabetes-and-type-2-diabetes
    August 24, 2021 - Most trials reporting mortality or CVD events over a follow-up duration of 6 years or less had few events … Categories and definitions used for adverse events were heterogenous across studies, and few trials ( … 3 trials) reported adverse events beyond 5 years of follow-up. 65 , 66 , 74 Five trials reported rates … Four studies of lifestyle interventions reported on musculoskeletal-related adverse events, 2 found no … Six pharmacologic trials found higher rates of GI adverse events vs controls: metformin (3 trials), acarbose
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/yzXkWEQV3pn95yd_pmXZXk
    December 15, 2020 - receiving placebo or no treatment, and that some adverse events resolve after discontinuing therapy. … Pooled analyses found no sig- nificant differences in the risk of serious adverse events (4 trials; RR … , 0.92 [95% CI, 0.45-1.85]), any adverse event (5 trials; RR, 1.01 [95% CI, 0.90-1.11]), renal adverseevents (3 trials; RR, 1.27 [95% CI, 0.31-3.55]), or study withdrawal due to adverse events (3 trials … No significant differences in risk of serious adverse events or withdrawal due to adverse events were
  16. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary21/depression-in-children-and-adolescents-screening-2009
    March 15, 2009 - events. … we calculated pooled absolute RDs for suicide-related adverse events (SREs) using data for a subset … Treatment-emergent adverse events from selective serotonin reuptake inhibitors by age group: Children … Suicidal adverse events in pediatric randomized, controlled clinical trials of antidepressant drugs are … To incorporate more conservative estimates of adverse events into the review, we included results from
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/R_cAa3AjFGQ2np_aQnzQGA
    February 11, 2025 - Compared with placebo, no statistically significant associations were observed for adverse events. … events. … events, se- rious adverse events, or gastrointestinal adverse events are shown in Figure 4. … KQ5: Harms of treatment Bisphosphonates Discontinua- tions due to adverse events 27 RCTs160-168,170,172,173,175,180 … events and serious adverse events and moderate for no effect on upper gastrointestinal adverse events
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lipid-disorders-in-children-screening
    August 19, 2021 - . † CVD events are defined as myocardial infarction or ischemic stroke. … and adolescents delay or reduce the incidence of health outcomes (e.g., cardiovascular disease [CVD] events … * CVD events are defined as myocardial infarction or ischemic stroke. … positives/negatives    KQ 5 (Treatment harms): All harms from: Lipid-lowering medications (e.g., adverseevents, long-term safety, overtreatment) Lifestyle modifications (e.g., nutritional, psychosocial)
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/UXw277rnvJ8e_Dfsh4V3K3
    July 26, 2022 - The data on health outcomes (KQ1) and adverse events (KQ4) did not allow for quantitative pooling because … of adverse events (n = 12 452). … Thirteen trials reported adverse events or serious adverse events of any kind,29-31,33,41,48,51,56,62,82,114,132,136 … although 7 of these trials only stated that no adverse events were reported or that no adverse events … and 25.4% to 71% of control group participants), and none reported rates of any adverse events to be
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening
    July 18, 2023 - There were no significant differences in Tanner staging or hormonal adverse events between statin and … of follow-up in individuals taking statins compared with control groups. 1 , 17 Studies reporting adverse … intervention trial did not mention harms, and the 3 supplement trials for FH reported that there were no adverse … Dyslipidemia In studies including individuals with FH or multifactorial dyslipidemia, gastrointestinal adverse … Childhood cardiovascular risk factors and adult cardiovascular events.

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