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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/lipid-disorders-in-children-screening
July 18, 2023 - Limited longer-term evidence shows few withdrawals due to adverse events, slightly higher rates of liver … events. … y with FH
Ezetimibe
1 (n = 138) New: 0
Similar rates of total adverse events in intervention … (simvastatin + ezetimibe)
1 (n = 248) New: 0
Similar rates of total adverse events in intervention … and control groups
Consistency NA, imprecise
High total adverse events in both the intervention
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/KbJjfcaP9XvhkP43u-7b9q
July 01, 2014 - , but risk for serious
adverse events did not differ. … events, serious adverse events, or
overall adverse events). … events (RR, 2.1 [CI, 1.0 to 4.5];
I2 � 0%), withdrawals due to adverse events (RR, 7.6 [CI,
1.1 to 52 … but not
with increased risk for serious adverse events. … events compared with
lamivudine (54, 55), consistent with the high prevalence of
adverse events with
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/colorectal-cancer-screening
May 18, 2021 - A register-based study: adverse events in colonoscopies performed in Sweden 2001-2013. … Patient-reported adverse events after colonoscopy in Norway. … Adverse events after outpatient colonoscopy in the Medicare population. … Adverse events after screening and follow-up colonoscopy. … Adverse events of computed tomography colonography: an Italian National Survey.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF_Y9vcT3eNPdHjTxPZsUZ
April 17, 2023 - This trial
was among postpartum patients, and no adverse events were re-
ported in the intervention … Harm
outcomes included any adverse events, dropout due to adverse
events, serious adverse events, suicide … events. … There was also an increased risk of
serious adverse events with SSRI use compared with placebo (OR, … The
absolute risk of serious adverse events was low, and evidence for
specific serious adverse events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan102/chronic-obstructive-pulmonary-disease-screening-2016
May 15, 2014 - What are the adverse effects of screening for COPD using prebronchodilator spirometry? … What are the adverse effects of screening for COPD, including the impact of targeted preventive services … What are the adverse effects of COPD treatment in this population? … events requiring unexpected or unwanted medical attention and/or resulting in death (e.g., requiring … hospitalization); adverse events reported by ≥5% of the study population; false reassurance for screen-negative
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-anxiety-children-adolescents
October 11, 2022 - , adverse events. … adverse events. … Regarding withdrawal due to adverse events, the pooled RR for CBT trials was 0.39 (95% CI, 0.08 to 1.87 … For both CBT and pharmacotherapy, serious adverse events were rare and the differences between treatment … The evidence suggests that suicide-related harms, serious adverse events, and withdrawal due to adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/breast-cancer-medications-for-risk-reduction
July 20, 2017 - Women may experience adverse effects due to these medications. … mortality; other beneficial outcomes (e.g., reduced fractures caused by certain medications)
KQs 3, 4: Adverse … effects (including but not limited to: thromboembolic events, cardiovascular events, metabolic disorders … , musculoskeletal symptoms, mental health, genitourinary outcomes, adverse breast outcomes, other malignancies … , ophthalmologic disorders, gastrointestinal/hepatobiliary disorders, other adverse events affecting
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary23/diabetes-mellitus-type-2-in-adults-screening-2008
June 15, 2008 - Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized … Systematic review and meta-analysis of clinically relevant adverse events from HMG CoA reductase inhibitor … Statin-related adverse events: a meta-analysis. Clin Ther 2006;28:26-35. … KQ5: adverse effects of treatment
24 studies. … β-Blockers: increase in withdrawals secondary to adverse events vs. placebo; NSD in total deaths.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-wqedxmwdpdE5BmzcBeTmn
December 01, 2009 - events and early dis-
continuation due to adverse effects. … Limitation: Examination of harms was limited to serious adverse
events, and existing systematic reviews … Closer monitoring may also be important
for reducing uncommon, but potentially serious, adverse
events … Common adverse events associated with an SSRI:
meta-analysis of early paroxetine data. … The abstract did not mention any serious adverse events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/yw_rbA_nQrCnkaN8X5t56S
January 01, 2001 - ● What are the adverse effects of diet or drug treatment? … We also included
any articles that examined adverse effects and harms of
screening or therapy for lipid … What are the adverse effects of screening? KQ4. … What are the adverse effects of diet or drug
treatment? … Short-
to medium-term adverse effects appear uncommon
with statins, but long-term effects are unknown
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2001
April 09, 2001 - What are the adverse effects of screening? … What are the adverse effects of diet or drug treatment? … , statins appear to have few important short- or medium-term (initiation to 5 years) adverse effects. … What are the adverse effects of screening? KQ4. … What are the adverse effects of diet or drug treatment?
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2wL_PmXmBxZQXX29D7nma5
September 01, 2021 - Asymptomatic pregnant persons who are at high risk for preeclampsia and have no prior adverse events … years or
older, personal history factors (eg, low birth weight or small for gestational age, previous adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/drug-use-illicit-screening
June 09, 2020 - events such as death and adverse events resulting in hospitalizations or study withdrawal reported at … , with no serious adverse events noted. … events. 125 , 130 , 139 Three studies (n = 638) found no differences in serious adverse events, but … events or study withdrawal due to adverse events vs placebo or pharmacotherapy. … events: 3 trials; RR, 1.54 (95% CI, 0.35 to 8.31); I 2 = 0%
Serious adverse events: 3 trials; RR
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Xbtq4oDQwVo7KgmSjnnDbz
November 01, 2021 - Serious adverse events from colonoscopy in
asymptomatic persons included perforations (4/10 000 procedures … No studies reported
serious adverse events
in persons without CTC. … Adverse
events of computed tomography colonography: an
Italian National Survey. … Adverse events
after screening and follow-up colonoscopy. … Adverse events after outpatient colonoscopy in the
Medicare population.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
August 26, 2014 - None of the dietary intervention studies explicitly reported adverse events. … Studies of physical activity interventions reported mostly minor adverse events, and intense physical … events during the trial and 6 specifically reported no adverse events 6 . … Few trials reported details about the adverse events, but most were minor, including musculoskeletal … Serious adverse events were rare.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
March 14, 2019 - improvements in intermediate outcomes as a result of antiviral treatment and reduction in risk of HBV-related adverse … outcomes as a result of antiviral treatment of chronic HBV infection and reduction in risk of HBV-related adverse … HBsAg or acquisition of anti-HBs)
KQ 6:
Harms of antiviral medications
Withdrawals due to adverse … events
Serious adverse events
KQ 4: Drug resistance; development of mutations or antibodies
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/hepatitis-b-virus-infection-screening
December 15, 2020 - Pooled analyses found no significant differences in the risk of serious adverse events (4 trials; RR, … 0.92 [95% CI, 0.45-1.85]), any adverse event (5 trials; RR, 1.01 [95% CI, 0.90-1.11]), renal adverse … events (3 trials; RR, 1.27 [95% CI, 0.31-3.55]), or study withdrawal due to adverse events (3 trials … No significant differences in risk of serious adverse events or withdrawal due to adverse events were … receiving placebo or no treatment, and that some adverse events resolve after discontinuing therapy.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/rQBBkz9CrHh4vp7ZnEkF-t
July 18, 2023 - FH
Ezetimibe 1 (n = 138)
New: 0
Similar rates of total adverse events in
intervention and control groups … 6-11 y
with FH
PCSK9 inhibitor 1 (n = 158)
New: 1
Similar rates of total adverse events in
intervention … events in
intervention and control groups
Consistency NA, imprecise High total adverse events
in both … Limited longer-term evidence shows few withdraw-
als due to adverse events, slightly higher rates of … events.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/sZN5HHS8w5Sar6bBPabsaB
June 01, 2008 - �-Blockers: increase in withdrawals secondary to adverse events vs.
placebo; NSD in total deaths. … events in the remaining unscreened group (1). … Systematic review and meta-analysis of adverse
events of low-dose aspirin and clopidogrel in randomized … Systematic review and
meta-analysis of clinically relevant adverse events from HMG CoA reductase
inhibitor … Statin-related adverse
events: a meta-analysis. Clin Ther. 2006;28:26-35. [PMID: 16490577]
131.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-depression-suicide-risk-children-adolescents
October 11, 2022 - or stress, bullying, maltreatment, adverse life events, and a difficult relationship with parents. … , bullying (either as perpetrators or as victims), adverse life events, early exposure to stress, maltreatment … events and serious adverse events compared with placebo; the differences were not statistically significant … , likely because of a small number of events due to poor reporting. … There were no significant differences in adverse events reported. 1 , 2
Response to Public Comment