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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening-prevent-fractures
November 18, 2021 - KQ 5 (Treatment harms):
Total adverse events.
Total serious adverse events. … Specific serious adverse events: Major cardiovascular events (i.e., myocardial infarction, stroke, cardiovascular … osteonecrosis of the jaw, atypical femur fractures, incident gastrointestinal cancer, serious gastrointestinal events … Discontinuations because of adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
November 18, 2021 - KQ 5 (Treatment harms):
Total adverse events.
Total serious adverse events. … Specific serious adverse events: Major cardiovascular events (i.e., myocardial infarction, stroke, cardiovascular … osteonecrosis of the jaw, atypical femur fractures, incident gastrointestinal cancer, serious gastrointestinal events … Discontinuations because of adverse events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/BXkaHRFGjwUCoyANeMSuTz
January 01, 2010 - The relative risk for adverse events associated with
hypertension is continuous and graded (2,8); systolic … Adverse Effects of Screening
for Hypertension
We identified 10 cohort studies examining the
adverse … These studies did not find any evidence for
adverse psychological effects. … Adverse Effects of Treatment of
Hypertension
Serious or life-threatening adverse drug reactions
have … Less serious adverse effects have
been noted to occur with most drugs (68).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/xUc_vXf7323faUQY7SePhT
January 01, 2002 - and its
likelihood of causing adverse effects. … the participants had definite or suspected
vascular disease.12,13
From our search for articles on adverse … Adverse Effects of Aspirin Therapy
Hemorrhagic stroke. … effect of aspirin, a reduction in nonfatal
myocardial infarction, cannot be directly equated to
an adverse … Adverse effects of low-dose
aspirin in a healthy elderly population.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uM5P-6XpsqVfEC2axGnZaD
November 16, 2020 - • A statistically nonsignificant increase in severe adverse events
was found with bupropion SR, but … may be associated with
an increased risk of general severe adverse events … Cardiac adverse events and other serious adverse events did not dif-
fer by type of NRT.63
The USPSTF … events (RR, 1.30 [95% CI, 1.00-
1.69]; 33 trials; n = 9631),83 cardiovascular adverse events (RR,
1.03 … events or cardiovascular severe adverse events was
found.13 Additionally, no statistically significant
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/coronary-heart-disease-screening-with-electrocardiography-2012
December 30, 2013 - , but it might also result in harms, including such adverse medication effects as gastrointestinal bleeding … Potential Harms of Detection
Adverse events directly associated with resting ECG are extremely rare … Adverse events associated with exercise ECG may include the triggering of a cardiovascular event, musculoskeletal … The overall risk for a serious adverse event (one that requires hospitalization or causes sudden death … The most important harm is exposure to potential adverse effects of invasive tests.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/obesity-in-children-and-adolescents-screening
June 18, 2024 - event or serious adverse events or decreases in self-esteem, body satisfaction, or disordered eating … events, serious adverse events, self-esteem, body satisfaction, or disordered eating
Outcomes reported … events: insufficient
Any adverse events: low for increased harm
Largest trial providing most of … events: insufficient
Any adverse events: low for increased harm
Multinational study, including … events: insufficient
Any adverse events: low for increased harm
Larger study conducted in the
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary20/depression-in-adults-screening-2009
December 15, 2009 - events and early discontinuation due to adverse effects. … Limitation: Examination of harms was limited to serious adverse events, and existing systematic reviews … Closer monitoring may also be important for reducing uncommon, but potentially serious, adverse events … Common adverse events associated with an SSRI: meta-analysis of early paroxetine data. … The abstract did not mention any serious adverse events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TkWNoq6KQb3SoZ54gscLCQ
July 25, 2016 - Antiviral
therapy was associated with higher risk of withdrawal due to adverse events vs placebo
or no … events (7 trials, n = 3223) (eFigure 15 in the
Supplement),35,36,38,40,41,43,82 or any adverse event … events
(RR, 2.41 [95% CI, 0.86 to 6.74]), withdrawal due to adverse events
(RR, 4.01 [95% CI, 0.86 to … events or experi-
encing any adverse event vs placebo. … adverse events vs
lamivudine, consistent with known adverse effects of interferon-
based therapies.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2013
September 15, 2013 - events. … events. … events, uterine abnormalities, cataracts, and other adverse effects. … cataracts, and other adverse effects. … The USPSTF also considered meta-analysis summary calculations of the number of adverse health events
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/early-food-allergen-introduction-infants-counseling
May 09, 2024 - allergenic foods (KQ1 only)
KQ2: Psychological harms (e.g., anxiety)
KQ4:
Withdrawal due to adverse … events, as reported in the studies
Serious adverse events attributable to the intervention, including
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cognitive-impairment-older-adults
March 06, 2025 - life) and harms due to labeling (insurance status, driving privileges, independence)
KQ 5: Serious adverse … events (e.g., death, serious adverse drug reactions), total adverse reactions from medications, withdrawals … due to adverse events, and unexpected medical attention (e.g., emergency department visits, hospitalizations
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/B73a4kJhxeaYyXK6gozbbY
May 24, 2022 - vitamin E or pla-
cebo, and no differences in risk of withdrawal due to adverse events
or specific adverse … but did not
indicate increased risk of serious adverse events or withdrawal due
to adverse events. … events, cardiovascular
events, or serious ocular adverse events
Three trials found that serious ocular … adverse events were
infrequent and occurred in similar proportions of patients
randomized to either … events or withdrawal due to adverse events
Consistent
Precise for the
AREDS formulation
but imprecise
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/falls-prevention-community-dwelling-older-adults-interventions
June 04, 2024 - Multifactorial Interventions
Adverse events were sparsely reported for multifactorial interventions … Four trials 12 , 15 , 16 , 18 reported adverse events in the intervention groups but did not provide … Serious adverse events related to the exercise intervention were measured in 7 trials, 18 , 43 , 54 , … related to the intervention and 1 trial 62 reporting less than 1% serious adverse events related to … events as 18% in the intervention group and 12% in the control group; however only 1 adverse event (
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/latent-tuberculosis-infection-screening
May 02, 2023 - A total of 345 patients (1.8%) receiving isoniazid discontinued treatment because of adverse events, … The RR of discontinuation due to adverse events among patients treated with isoniazid vs placebo was … Rates of discontinuation because of adverse events were reported in all 4 included RCTs, but 1 trial … Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: … events and other gastrointestinal adverse events
Fair
Harm ascertainment techniques not well described
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/zVVRY6wa4Sgj-EJb3BRcVy
November 01, 2013 - events. … events. … events, uterine ab-
normalities, cataracts, and other adverse effects. … , cataracts, and other adverse effects. … The USPSTF also considered meta-analysis summary
calculations of the number of adverse health events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qpv8h6ZMbYLYzakVrNQoj2
October 11, 2022 - , and adverse events. … Differences in suicide-related outcomes and adverse events for pharmacotherapy when
compared with placebo … The TADS trial reported a higher but not statistically sig-
nificant difference in adverse events for … One
study53-55 reported on adverse events, serious adverse events, and
other harms during the 12- to … events and serious adverse events, precise effects
unclear owing to inconsistent study reporting
Collaborative
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-wqedxmwdpdE5BmzcBeTmn
December 01, 2009 - events and early dis-
continuation due to adverse effects. … Limitation: Examination of harms was limited to serious adverse
events, and existing systematic reviews … Closer monitoring may also be important
for reducing uncommon, but potentially serious, adverse
events … Common adverse events associated with an SSRI:
meta-analysis of early paroxetine data. … The abstract did not mention any serious adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/early-food-allergen-introduction-infants-counseling
September 05, 2024 - Rates of introduction of allergenic foods (KQ1 only)
KQs 2, 4:
Withdrawal from study due to adverse … events, as reported in the studies
Serious adverse events attributable to the intervention, including
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan102/chronic-obstructive-pulmonary-disease-screening
May 15, 2014 - What are the adverse effects of screening for COPD using prebronchodilator spirometry? … What are the adverse effects of screening for COPD, including the impact of targeted preventive services … What are the adverse effects of COPD treatment in this population? … events requiring unexpected or unwanted medical attention and/or resulting in death (e.g., requiring … hospitalization); adverse events reported by ≥5% of the study population; false reassurance for screen-negative