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www.uspreventiveservicestaskforce.org/home/getfilebytoken/B_Ae7DdLL7DNauBLXC-ptu
June 01, 2003 - We also searched for evidence
of the adverse effects of screening and treatment. … In the trials of galantamine,
the dropout rate attributable to adverse events in
participants ranged … In the trials of
rivastigmine, the adverse effect rate was from 5%
to 20% higher. … In trials of higher-dose (10 mg)
donepezil, the adverse effect rate was about 8%
higher. … The odds ratio (OR) for
dropout because of adverse events among people
who took tacrine was 5.7 (95%
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6fMLEz4CfAVoj9YBYVbm73
April 17, 2018 - evaluating the potential harms of supplementation are
needed, particularly studies on calcium and potential adverse … 0.06% to 0.60%), and the pooled RR was 1.18
(95% CI, 1.04 to 1.35).1
The most commonly reported other adverse … A few studies reported on other
serious adverse events, but these events were rare and noted by the
authors
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - Aspirin for the primary prevention of cardiovascular events: an update of evidence for the U.S. … Feasibility of conducting a primary prevention trial of low-dose aspirin for major adverse cardiovascular … events in older people in Australia: results from the ASPirin in Reducing Events in the Elderly (ASPREE … ASCEND: A Study of Cardiovascular Events iN Diabetes [clinical trial]. … We used a continuity correction factor of 0.5 if a group reported no events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/aHpXYasjc3n6zhaTtoWMwK
August 01, 2016 - One RCT (n = 63) included in KQ4 and KQ5 reported on harms.26
Rates of reported adverse events were … Key question 6:
Harms of
treatment
1 62 RCT Incidence of self-reported adverse events
were similar between … Generally healthy
asymptomatic
nonpregnant adults
Unclear if adverse events
were prespecified. … One trial assessed harms of medications; adverse events were
similar between groups randomized to valacyclovir
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary26/tobacco-use-in-children-and-adolescents-primary-care-interventions-2013
December 11, 2012 - bupropion 32 , 34 , 37 , 1 trial found that a greater proportion of bupropion users (64%) reported an adverse … The other 2 studies, however, reported no increased risk for several specific adverse effects of bupropion … What adverse effects are associated with interventions to improve tobacco cessation rates or prevent … Appendix Figure 1 is an analytic framework for the key questions of this report that depicts the events … The figure also depicts the possibility of harms or adverse events occurring as a result of the interventions
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ER_LzXdmdRcZ463r4UrGtz
September 01, 2005 - The USPSTF found fair evidence regarding important
adverse ethical, legal, and social consequences that … The USPSTF also found insufficient evidence regarding
important adverse ethical, legal, and social consequences … Genetic testing may lead to potential adverse ethical,
legal, and social consequences, such as insurance … decrease inci-
dence of estrogen receptor–positive breast cancer; however,
it is also associated with adverse … There is good-quality ev-
idence on the harms of prophylactic tamoxifen (1), includ-
ing thromboembolic events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lung-cancer-screening
August 16, 2018 - treatment (e.g., surgical resection for a benign nodule), and harms of workup (e.g., biopsy leading to an adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-dental-caries-in-children-younger-than-age-5-years-screening-and-interventions1
December 07, 2021 - permanent teeth. 1 , 22 Four trials (n = 4141) found no differences in risk of fluorosis or any other adverse … Absence of fluoride varnish-related adverse events in caries prevention trials in young children, United
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/2015annlrpt%20(4).pdf
January 01, 2016 - Harms of preventive services can include adverse effects of the service itself, as well as
the harms … For women who are at increased risk for
breast cancer and at low risk for adverse medication effects … in asymptomatic adults at low risk for such events. … screening with resting or exercise electrocardiography for the prediction of coronary heart disease events … in asymptomatic adults who are at intermediate or high risk for such events.
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/2015annlrpt%20(4)_0.pdf
January 01, 2016 - Harms of preventive services can include adverse effects of the service itself, as well as
the harms … For women who are at increased risk for
breast cancer and at low risk for adverse medication effects … in asymptomatic adults at low risk for such events. … screening with resting or exercise electrocardiography for the prediction of coronary heart disease events … in asymptomatic adults who are at intermediate or high risk for such events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
August 20, 2019 - raloxifene, or aromatase inhibitors to women at increased risk for breast cancer and at low risk for adverse … raloxifene, or aromatase inhibitors to women at increased risk for breast cancer and at low risk for adverse … per 1000 women for tamoxifen (4 trials), 79-82 9 fewer events per 1000 women for raloxifene (2 trials … ), 83 , 84 and 16 fewer events per 1000 women for aromatase inhibitors (2 trials), 85-89 assuming 5 … tamoxifen had more cataract procedures compared with placebo or raloxifene. 79 , 90 The most common adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/HyxpKaXv6BVDKBHQ74yWeL
December 10, 2019 - Repair (CAESAR) trial, the early interven-
tion group had a higher percentage of patients with any adverse … events (19% vs 5%; P < .01), any major morbidity related to repair
at 30 days (18% vs 6%; P = .01), … Endovascular Options for Treat-
ing Aneurysms Early (PIVOTAL) trial reported similar rates of ad-
verse events … mortality and
reintervention.1
Two propranolol trials reported high discontinuation rates re-
lated to adverse … events (38% and 60% of participants in the pro-
pranolol groups withdrew from the trials).
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening-2011
January 15, 2011 - Clinicians should provide patient education on how to use drug therapies to minimize adverse effects. … bisphosphonates, the evidence demonstrates no definitive increase in the risk for serious gastrointestinal adverse … events (for example, perforations, ulcers, bleeding, esophagitis, or esophageal ulceration) in persons … Raloxifene and estrogen are associated with higher rates of thromboembolic events compared with placebo
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening-july-2014
July 08, 2014 - carotid plaque structure or intima–media thickness and their association with cardiovascular disease events … VACS reported 4 events in the CEA group and none in the medical therapy group. … USPSTF reviewed studies using Medicare data that reported the relationship between patient volume and adverse … events after CEA.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening
February 02, 2021 - artery for the past 6 months, while another enrolled participants with no history of cerebrovascular events … treatment
Inadequate direct evidence that screening for asymptomatic carotid artery stenosis reduces adverse … asymptomatic patients with carotid artery stenosis using CEA or CAS provides no to small benefit in reducing adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/e6_WqcwDGhgT6bQfmk3Hqj
February 02, 2021 - treatment
• Inadequate direct evidence that screening for asymptomatic carotid artery stenosis reduces adverse … asymptomatic patients with carotid artery stenosis using CEA or CAS provides
no to small benefit in reducing adverse … artery for the past 6
months, while another enrolled participants with no history of
cerebrovascular events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/falls-prevention-in-older-adults-counseling-and-preventive-medication-2012
May 15, 2012 - Minor adverse outcomes associated with specific interventions included increased fall-related outpatient … after exercise, minor local skin irritation or infection with use of hip protectors, gastrointestinal adverse … Many of the studies on vitamin D did not report on adverse events, and many included other interventions
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/tfannrpt2011.pdf
January 01, 2012 - The potential harms of preventive
services can include adverse effects of the service itself
or inaccurate … clinicians discuss chemoprevention with women at high risk for breast cancer and at
low risk for adverse … in adults at low risk for CHD events. … in adults at increased risk for CHD events. … recommend routine screening for developmental dysplasia of the hip
in infants as a means to prevent adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/abdominal-aortic-aneurysm-screening-2014
June 23, 2014 - rate after 2 years of followup did not differ between the two groups; however, the number of reported events … high discontinuation rate over 2 years (60% of participants receiving the active intervention) due to adverse … events, such as fatigue, shortness of breath, and bradycardia 35 . … Three RCTs of antibiotics found a low rate of adverse events over 4 to 15 weeks. 1 , 2
Estimate of
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/2022-annual-report-to-congress.pdf
January 01, 2022 - lifestyle interventions, especially among populations
at highest risk for progression to diabetes and adverse … lifestyle interventions, especially
among populations at highest risk for progression to diabetes and adverse … weight at the beginning of pregnancy and excess gestational weight gain have
been associated with adverse … lifestyle interventions, especially among populations at
highest risk for progression to diabetes and adverse … assess the
balance of benefits and harms of initiating a statin for the primary prevention
of CVD events