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  1. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/abdominal-aortic-aneurysm-screening
    December 10, 2019 - Techniques for Aortic Aneurysm Repair [EUROSTAR]) ( Table 4 ). 40 , 71 Only the ADAM trial reported adverse … reported in the 2 trials of EVAR. 29 , 69 In the CAESAR trial, the percentage of patients with any adverse … at 3- to 4-year follow-up. 40 , 71 Eight short-term drug trials (n = 1598) reported high rates of adverse … In the CAESAR trial, the early intervention group had a higher percentage of patients with any adverse … Pharmacotherapy vs placebo 8 (1598) With the exception of the 2 propranolol trials reporting high adverse
  2. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary94/syphilis-infection-in-pregnancy-screening-2009
    May 15, 2009 - Harms include testing and follow-up for false-positive test results and adverse effects from penicillin … , code; Current Procedural Terminology code; or procedural code for anaphylactic shock, unspecified adverseEvents after exposure were compared with each patient's baseline period 183 d before index date of study … attributed to oral route, preselection if penicillin allergy was identified, mislabeling as allergic events … Mentions risks of misdiagnosis, including adverse penicillin reaction, stigma, and social consequences
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-prophylaxis-myocardial-infarction-preventive-medication-1996
    January 01, 1996 - This represents an absolute risk reduction of less than two events per thousand individuals per year. … been proposed for persons without neurologic symptoms who are at increased risk for thromboembolic events … in middle-aged and older men whose risks of a first MI are sufficiently high to warrant the possible adverse … should be made on an individual basis after the benefits of decreased risk of ischemic cardiovascular events … Nyman I, Larsson H, Wallentin L Prevention of serious cardiac events by low-dose aspirin in patients
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/by8VJVre6h6BmadrGxaFMM
    April 01, 2016 - Treatment and Dosage The optimal dose of aspirin to prevent CVD events is not known. … Few fatal stroke events were reported in trials. … Initiating aspirin use during ages 50 to 59 years and continuing unless contraindicated by an adverse … Initiating aspirin use during ages 60 to 69 years and continuing unless contraindicated by an adverse … Aspirin for primary prevention of cardiovascular disease events.
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/XW6XUe2wRmkM-6Rrbn_462
    February 01, 2023 - Eligible harms outcomes for intervention studies (KQ 6) included medication-related adverse eventsevents, which would fall within this review’s scope. … events between groups (headache, nausea).81 It was unclear if adverse events were prespecified. … Reactions"] OR [mh "Long Term Adverse Effects"] OR [mh "Patient Harm"] OR harm OR harms OR "adverseevents (e.g., adverse drug reactions related to antiviral medications); psychosocial harms related
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/child-maltreatment-primary-care-interventions
    March 19, 2024 - families or worsening of inequities (eTable 51 in the  JAMA  Supplement). 33 , 34 , 51-53 In 1 study, adverse … found that the child maltreatment intervention was associated with slightly increased risk of a serious adverse … (43% vs 38%; calculated RR, 1.15 [95% CI, 1.03-1.25]). 33 However, no adverse events were judged to … The numbers of specific adverse events (miscarriages/terminations, stillbirth/neonatal death/infant death … Two studies did not report statistically significant adverse events between study groups.
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/MLeu_yFpPwzcZwKG6fw5ZY
    April 26, 2022 - In contrast, the reduction of these 2 events was more evenly balanced for women. … fatal CVD events resulting from nonfatal CVD events that were prevented prior to stopping aspirin. … observed in the aspirin primary prevention trials, but analyses by others have suggested there is no adverse … Net QALY assess- ments showed strong adverse influence from small disutilities as- sociated with aspirin … Effect of aspirin on cardiovascular events and bleeding in the healthy elderly.
  8. www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-july-2016
    August 09, 2016 - generally well tolerated in children and adolescents with familial hypercholesterolemia, with transient adverse … is generally asymptomatic in childhood and adolescence and is rarely associated with cardiovascular events … The adverse effects of long-term use of lipid-lowering pharmacotherapy and lifestyle modification (including … Some experts recommend starting statin use at age 8 or 10 years; others, concerned with adverse effects … Cardiovascular events rarely occur in the first 2 decades of life, typically taking place during the
  9. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-pregnancy-screening-september-2018
    September 04, 2018 - association of implementing a screening program with the incidence of congenital syphilis and other adverse … During this same period, in pregnant women infected with syphilis, the incidence of all adverse outcomes … events in women with a history of penicillin allergy. … Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis. … Reported estimates of adverse pregnancy outcomes among women with and without syphilis: a systematic
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/DMDPeSf_nEUM-HrVrX6c7U
    June 20, 2017 - mental health and psychological issues, asthma, obstructive sleep apnea, orthopedic problems, and adverse … Obesity in childhood and adolescence may continue into adulthood and lead to adverse cardiovascular … Obesity in childhood and adolescence may continue into adulthood and lead to adverse cardiovascular … Five trials found no adverse or serious adverse events in the interven­ tion group. … Rates of discontinua­ tion due to adverse effects were twice as common in the interven­ tion group as
  11. www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening
    January 14, 2025 - A pooled analysis of 21 RCTs found no significant difference in serious adverse events. … One trial reported a statistically significant increase in gastrointestinal adverse events in the treatment … of 26 RCTs (representing 27 comparisons) found no significantly increased risk of gastrointestinal adverseevents in participants taking bisphosphonates compared with those taking placebo. … events (5 RCTs) or upper gastrointestinal tract adverse events (4 trials), although the CIs were wide
  12. www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-2008
    October 15, 2008 - 3.8 per 10,000 procedures. 4 Serious complications—defined as deaths attributable to colonoscopy or adverse … pain, and cardiovascular events—are significantly more common, occurring in an estimated 25 per 10,000 … Fecal Occult Blood Tests No current studies adequately address any adverse effects of high-sensitivity … net benefit, where the number of colonoscopies represents a proxy for resource utilization as well as adverseevents from screening.
  13. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary14/lung-cancer-screening
    March 09, 2021 - Less than one-third of patients in most studies experienced treatment-related adverse events. … Adverse events reported in ≥10% of patients included pulmonary events (eg, air leak, pleural effusion … intervention, missing data, and sources of survival outcomes often lacking; potential selective reporting of adverseAdverse events were experienced by most patients, but most were of mild or moderate severity. … Adverse events reported in ≥10% of patients included were pulmonary events (eg, cough, dyspnea, pneumonitis
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan15/depression-in-children-and-adolescents-screening
    September 15, 2013 - Suicidality or death Death from suicide or other causes Other serious psychiatric events … suicide attempts) Triggering symptoms of mania Discontinuation of medication due to adverseevents Side effects of medications KQs 1, 3, 4–6 : All other outcomes not listed in
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-june-2017
    June 20, 2017 - events in the intervention group, 26 , 47 , 49 and 2 additional trials (published in the same article … ) reported that there were no serious adverse events. 44 Five trials similarly found no group differences … Adverse effects were also frequently reported by those receiving placebo. … The analytic framework also depicts the possible adverse events occurring after screening (KQ2) or treatment … effects, 5 reported no adverse or serious adverse effects associated with the interventions.
  16. www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-in-adults-screening
    September 24, 2019 - preterm birth. 9 The presence of asymptomatic bacteriuria has not been shown to increase the risk of adverse … In addition, there are newer concerns about antibiotic use, such as antimicrobial resistance and adverse … treatment in nonpregnant women 34 , 36 and 2 studies in older adults 32 , 35 reported on rates of adverseevents associated with treatment of asymptomatic bacteriuria. … The relationship between asymptomatic bacteriuria and adverse pregnancy outcomes is related to a combination
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/oPmYxryXGu2occANaReagc
    August 01, 2022 - Treatment Discontinuation With Isoniazid Rates of treatment discontinuation because of adverse events … A total of 345 patients (1.8%) receiving isoniazid discontinued treatment because of adverse events, … The RR of discontinuation due to adverse events among patients treated with isoniazid vs pla- cebo was … Rates of discontinuation because of adverse events were re- ported in all 4 included RCTs, but 1 trial … Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid:
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/s2xawZNAWVC5qgGyTT6r8m
    October 01, 2015 - evidence on screening for iron deficiency anemia in asymptomatic children ages 6 to 24 months to prevent adverse … Reported adverse events of treatment with iron include limited gastrointestinal symptoms, darkening color … trial from 1991 that was not included in the previous review found no difference in overall or specific adverseevents, including gastrointestinal events.12 Estimate of Magnitude of Net Benefit Overall, the USPSTF
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/gWJU-ZynehGyLBVYtDmMow
    May 01, 2009 - Harms include testing and follow-up for false-positive test results and adverse effects from penicillin … 2003 through 31 July 2008 and used the search terms penicillin, pregnancy, infant, newborn, fetus, adverseEvents after exposure were compared with each patient’s baseline period 183 d before index date of study … attributed to oral route, preselection if penicillin allergy was identified, mislabeling as allergic events … Mentions risks of misdiagnosis, including adverse penicillin reaction, stigma, and social consequences
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/5P_7f2rbEquA-ZR-fJJfHK
    April 27, 2021 - blood pressure monitoring offers the most evidence- based risk information for future cardiovascular events … suggested that screening is not associated with any substantial short- term quality of life changes or adverse … Seven studies (n = 3505) reported minor adverse events such as sleep distur- bance, pain/discomfort, … White-coat hypertension and cardiovascular events: a meta-analysis. … Cardiovascular events and mortality in white coat hypertension: a systematic review and meta-analysis

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