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www.uspreventiveservicestaskforce.org/uspstf/recommendation/falls-prevention-in-older-adults-interventions-2018
April 17, 2018 - Eight studies (n=4107) evaluating exercise interventions reported on harms; in general, adverse events … were minor. 8 , 10 The most common adverse events included pain or bruising related to exercise. … or severe adverse events, although ascertainment of adverse events was unclear. 8 One study on a single … psychological intervention reported no adverse events. 25 The remaining studies did not report on harms … or adverse events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VNs-WaxpPcsodxCb57gYmn
January 03, 2017 - In addition to mortality, other adverse health
outcomes associated with untreated OSA include cardiovascular … mortality independently, beyond the contributions
of age, BMI, and other confounding factors.1 Other adverse … Overall, 2% to 47% of trial participants reported any
adverse effects from treatment with CPAP, including … been
found to be associated with an increased risk of all-cause and car-
diovascular mortality.1 Other adverse … performance; and decreased quality of life.1 However, it is unclear
what role OSA plays in causing these adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
July 17, 2018 - , discrimination, or risk reclassification), and serious
adverse events. … Harms included any serious adverse event requiring
unexpected or unwanted medical attention resulting … evidence on major bleeding from
low-dose aspirin
KQ5: hsCRP-Guided Statin Treatment Harms
Serious adverse … but not in other serious
adverse events
There were 3.0% cases of diabetes in the
rosuvastatin group … Limited follow-up This trial should be interpreted in
the context of the larger body of
evidence on adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication-september-2014
September 09, 2014 - more of the following risk factors:
History of preeclampsia, especially when accompanied by an adverse … events. … Assessment of Risk for Adverse Effects
Low-dose aspirin use in women at increased risk for preeclampsia … Eighteen trials reported on the outcome of perinatal mortality (with 4 smaller studies reporting no events … Seven trials reported adverse events; however, most were determined to be unrelated to treatment.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/8JYDupJfG6LdRn7A6FkqXX
March 01, 2016 - antioxidant vitamins
and mineral supplements is not associated with increased risk of
most serious adverse … events. … with
greater likelihood of withdrawal vs sham therapy; there were no
differences in serious or other adverse … events, but estimates
were imprecise.1,4,6,7
Current Practice
About half of US adults older than 65 … event, serious adverse
events, serious ocular events, or withdrawal due to adverse events.1
Treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening
January 24, 2017 - Overall, 2% to 47% of participants in trials reporting any harms had specific adverse events while using … Across studies that reported any discontinuation because of adverse events, 7% of patients using MADs … In general, the adverse events related to CPAP treatment were likely short-lived and could be alleviated … Adverse effects may limit adherence to treatment. … and Associated Events.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening-january-2017
January 24, 2017 - Overall, 2% to 47% of participants in trials reporting any harms had specific adverse events while using … Across studies that reported any discontinuation because of adverse events, 7% of patients using MADs … In general, the adverse events related to CPAP treatment were likely short-lived and could be alleviated … Adverse effects may limit adherence to treatment. … and Associated Events.
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/perinatal-depression-interventions-to-prevent
February 23, 2023 - intensive care unit admission
Serious harms reported in trials of treatment benefit
Withdrawals due to adverse … events in trials of treatment benefit
KQ 1: Maternal behavioral outcomes (e.g., increase in physical
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
July 11, 2017 - Among 14 trials of behavioral interventions that reported on adverse events, none reported any serious … adverse events. … Behavioral Counseling Interventions
Of the 88 trials reviewed by the USPSTF, 14 specifically reported on adverse … events. 3 No trials reported any serious adverse events related to the counseling intervention. … events.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-familial-hypercholesterolemia/lipid-disorders-in-children-screening
August 09, 2016 - Bile acid–sequestering agents were commonly associated with adverse gastrointestinal symptoms and poor … No severe, permanent harms of statins were reported, and reported treatment adverse events usually did … events were reported sporadically. … events or with different rates of adverse events compared with a control group at 12 weeks. 34
Relationship … Treatment studies should systematically report adverse effects of treatment.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-familial-hypercholesterolemia/lipid-disorders-in-children-screening-july-2016
August 09, 2016 - Bile acid–sequestering agents were commonly associated with adverse gastrointestinal symptoms and poor … No severe, permanent harms of statins were reported, and reported treatment adverse events usually did … events were reported sporadically. … events or with different rates of adverse events compared with a control group at 12 weeks. 34
Relationship … Treatment studies should systematically report adverse effects of treatment.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication
March 15, 2009 - Enteric-coated or buffered preparations do not clearly reduce the adverse gastrointestinal effects of … Clinicians should inform patients about the adverse consequences of gastrointestinal bleeding because … increases the risk for major bleeding events in men and women. … The sex-specific meta-analysis of RCTs described above reported adverse events with aspirin use in the … primary prevention of cardiovascular events in 51,342 women and 44,114 men. 3 Major bleeding events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
March 15, 2009 - Enteric-coated or buffered preparations do not clearly reduce the adverse gastrointestinal effects of … Clinicians should inform patients about the adverse consequences of gastrointestinal bleeding because … increases the risk for major bleeding events in men and women. … The sex-specific meta-analysis of RCTs described above reported adverse events with aspirin use in the … primary prevention of cardiovascular events in 51,342 women and 44,114 men. 3 Major bleeding events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/suicide-risk-in-adolescents-adults-and-older-adults-screening
May 20, 2014 - Risk factors for suicide attempt include presence of a mental health disorder; serious adverse childhood … Other important risk factors for suicide attempt include serious adverse childhood events; family history … Potential Harms of Screening
Three studies reported on the potential adverse effects of screening … events were documented in the studies. … Few treatment trials in adults reported adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary29/obstructive-sleep-apnea-in-adults-screening
November 15, 2022 - per hour), moderate (16-30 events per hour), and severe (>30 events per hour). … Overall, too few events occurred to draw conclusions. … In general, the adverse events related to positive airway pressure treatment were likely short-lived … Common adverse events included oral or nasal dryness, eye or skin irritation, and rash. … : overall, too few events were observed to draw conclusions
Mortality and cardiovascular events:
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/cognitive-impairment-in-older-adults-screening
February 25, 2020 - Adverse events were significantly higher in patients receiving AChEIs, and more patients receiving AChEIs … Memantine was better tolerated, with no increase in adverse events or withdrawal rates compared with … Overall, there was no increase in serious adverse events in patients taking AChEIs. … However, some individual studies reported increased rates of serious adverse events, such as bradycardia … Adequate evidence that AChEIs are associated with adverse effects, which overall are small but occasionally
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/b5LjDb3-UoPV8LEWavJWB8
February 01, 2010 - , any seri-
ous adverse event, or discontinuation
caused by adverse events. … In the large
12-month sibutramine trial, serious
adverse events were reported by 2.7%
of patients in … Weight-
management programs for which pre-
specified adverse events that resulted
in death, hospitalization … No minimum follow-up is required
for serious (ie, requiring urgent medical care) adverse events (KQ3) … For trials that were not included for KQ1 or KQ2, outcomes were limited to serious
adverse events such
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/36geybKjEXsHDoPkRR5KVZ
June 01, 2008 - review for this current recommendation focused on evidence that
early treatment prevented long-term adverse … USPSTF reviewed the evidence on early treat-
ment of type 2 diabetes mellitus in preventing long-term
adverse … No studies reported adverse effects of receiving a
diagnosis of IFG or IGT, and no studies examined … Angiotensin-converting en-
zyme inhibitors and statins have reasonably low levels of
serious adverse … The relationship between
glucose and incident cardiovascular events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Wx_w92ukxeDvNShoRQXbhP
September 06, 2016 - A few studies also reported on gastrointestinal adverse
events. … -
nificant increased RR of gastrointestinal adverse events (RR, 1.60
[95% CI, 0.76-3.40]) in 2 studies … .2 All 5 studies also reported on
discontinuation of treatment because of adverse events. … events. … Adverse
events with 4 months of rifampin therapy or 9
months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/thyroid-cancer-screening
May 09, 2017 - Permanent harm was generally defined as an adverse outcome persisting beyond 6 months. … The most common adverse effect of radioactive iodine on the salivary glands was xerostomia (dry mouth … all persons diagnosed with papillary thyroid cancer receive treatment, so there is the potential of adverse … e Study reported adverse reproductive outcomes related to birth rate and median time to first delivery … No evidence-reporting bias for commonly reported adverse outcomes.