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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/abdominal-aortic-aneurysm-screening
December 10, 2019 - Techniques for Aortic Aneurysm Repair [EUROSTAR]) ( Table 4 ). 40 , 71
Only the ADAM trial reported adverse … reported in the 2 trials of EVAR. 29 , 69 In the CAESAR trial, the percentage of patients with any adverse … at 3- to 4-year follow-up. 40 , 71
Eight short-term drug trials (n = 1598) reported high rates of adverse … In the CAESAR trial, the early intervention group had a higher percentage of patients with any adverse … Pharmacotherapy vs placebo
8 (1598)
With the exception of the 2 propranolol trials reporting high adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary94/syphilis-infection-in-pregnancy-screening-2009
May 15, 2009 - Harms include testing and follow-up for false-positive test results and adverse effects from penicillin … , code; Current Procedural Terminology code; or procedural code for anaphylactic shock, unspecified adverse … Events after exposure were compared with each patient's baseline period 183 d before index date of study … attributed to oral route, preselection if penicillin allergy was identified, mislabeling as allergic events … Mentions risks of misdiagnosis, including adverse penicillin reaction, stigma, and social consequences
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-prophylaxis-myocardial-infarction-preventive-medication-1996
January 01, 1996 - This represents an absolute risk reduction of less than two events per thousand individuals per year. … been proposed for persons without neurologic symptoms who are at increased risk for thromboembolic events … in middle-aged and older men whose risks of a first MI are sufficiently high to warrant the possible adverse … should be made on an individual basis after the benefits of decreased risk of ischemic cardiovascular events … Nyman I, Larsson H, Wallentin L Prevention of serious cardiac events by low-dose aspirin in patients
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/by8VJVre6h6BmadrGxaFMM
April 01, 2016 - Treatment and Dosage
The optimal dose of aspirin to prevent CVD events
is not known. … Few fatal stroke events were
reported in trials. … Initiating aspirin use during ages 50 to 59 years
and continuing unless contraindicated by an adverse … Initiating aspirin use during ages 60 to 69 years and
continuing unless contraindicated by an adverse … Aspirin
for primary prevention of cardiovascular disease events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/XW6XUe2wRmkM-6Rrbn_462
February 01, 2023 - Eligible harms
outcomes for intervention studies (KQ 6) included medication-related adverse events … events, which would fall
within this review’s scope. … events between groups (headache, nausea).81
It was unclear if adverse events
were prespecified. … Reactions"] OR [mh "Long Term Adverse
Effects"] OR [mh "Patient Harm"] OR harm OR harms OR "adverse … events (e.g.,
adverse drug reactions related to antiviral
medications); psychosocial harms related
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/child-maltreatment-primary-care-interventions
March 19, 2024 - families or worsening of inequities (eTable 51 in the JAMA Supplement). 33 , 34 , 51-53 In 1 study, adverse … found that the child maltreatment intervention was associated with slightly increased risk of a serious adverse … (43% vs 38%; calculated RR, 1.15 [95% CI, 1.03-1.25]). 33 However, no adverse events were judged to … The numbers of specific adverse events (miscarriages/terminations, stillbirth/neonatal death/infant death … Two studies did not report statistically significant adverse events between study groups.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/MLeu_yFpPwzcZwKG6fw5ZY
April 26, 2022 - In contrast, the reduction of these 2 events was more
evenly balanced for women. … fatal CVD events resulting from nonfatal CVD events that were
prevented prior to stopping aspirin. … observed in the aspirin primary
prevention trials, but analyses by others have suggested there is
no adverse … Net QALY assess-
ments showed strong adverse influence from small disutilities as-
sociated with aspirin … Effect of aspirin on
cardiovascular events and bleeding in the healthy
elderly.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-july-2016
August 09, 2016 - generally well tolerated in children and adolescents with familial hypercholesterolemia, with transient adverse … is generally asymptomatic in childhood and adolescence and is rarely associated with cardiovascular events … The adverse effects of long-term use of lipid-lowering pharmacotherapy and lifestyle modification (including … Some experts recommend starting statin use at age 8 or 10 years; others, concerned with adverse effects … Cardiovascular events rarely occur in the first 2 decades of life, typically taking place during the
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-pregnancy-screening-september-2018
September 04, 2018 - association of implementing a screening program with the incidence of congenital syphilis and other adverse … During this same period, in pregnant women infected with syphilis, the incidence of all adverse outcomes … events in women with a history of penicillin allergy. … Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis. … Reported estimates of adverse pregnancy outcomes among women with and without syphilis: a systematic
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DMDPeSf_nEUM-HrVrX6c7U
June 20, 2017 - mental health and
psychological issues, asthma, obstructive sleep apnea, orthopedic problems, and adverse … Obesity in childhood and adolescence may continue into
adulthood and lead to adverse cardiovascular … Obesity in childhood and adolescence may continue into
adulthood and lead to adverse cardiovascular … Five
trials found no adverse or serious adverse events in the interven
tion group. … Rates of discontinua
tion due to adverse effects were twice as common in the interven
tion group as
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening
January 14, 2025 - A pooled analysis of 21 RCTs found no significant difference in serious adverse events. … One trial reported a statistically significant increase in gastrointestinal adverse events in the treatment … of 26 RCTs (representing 27 comparisons) found no significantly increased risk of gastrointestinal adverse … events in participants taking bisphosphonates compared with those taking placebo. … events (5 RCTs) or upper gastrointestinal tract adverse events (4 trials), although the CIs were wide
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-2008
October 15, 2008 - 3.8 per 10,000 procedures. 4 Serious complications—defined as deaths attributable to colonoscopy or adverse … pain, and cardiovascular events—are significantly more common, occurring in an estimated 25 per 10,000 … Fecal Occult Blood Tests
No current studies adequately address any adverse effects of high-sensitivity … net benefit, where the number of colonoscopies represents a proxy for resource utilization as well as adverse … events from screening.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary14/lung-cancer-screening
March 09, 2021 - Less than one-third of patients in most studies experienced treatment-related adverse events. … Adverse events reported in ≥10% of patients included pulmonary events (eg, air leak, pleural effusion … intervention, missing data, and sources of survival outcomes often lacking; potential selective reporting of adverse … Adverse events were experienced by most patients, but most were of mild or moderate severity. … Adverse events reported in ≥10% of patients included were pulmonary events (eg, cough, dyspnea, pneumonitis
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan15/depression-in-children-and-adolescents-screening
September 15, 2013 - Suicidality or death
Death from suicide or other causes
Other serious psychiatric events … suicide attempts)
Triggering symptoms of mania
Discontinuation of medication due to adverse … events
Side effects of medications
KQs 1, 3, 4–6 : All other outcomes not listed in
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-june-2017
June 20, 2017 - events in the intervention group, 26 , 47 , 49 and 2 additional trials (published in the same article … ) reported that there were no serious adverse events. 44 Five trials similarly found no group differences … Adverse effects were also frequently reported by those receiving placebo. … The analytic framework also depicts the possible adverse events occurring after screening (KQ2) or treatment … effects, 5 reported no adverse or serious adverse effects associated with the interventions.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-in-adults-screening
September 24, 2019 - preterm birth. 9
The presence of asymptomatic bacteriuria has not been shown to increase the risk of adverse … In addition, there are newer concerns about antibiotic use, such as antimicrobial resistance and adverse … treatment in nonpregnant women 34 , 36 and 2 studies in older adults 32 , 35 reported on rates of adverse … events associated with treatment of asymptomatic bacteriuria. … The relationship between asymptomatic bacteriuria and adverse pregnancy outcomes is related to a combination
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/oPmYxryXGu2occANaReagc
August 01, 2022 - Treatment Discontinuation With Isoniazid
Rates of treatment discontinuation because of adverse events … A total of 345 patients (1.8%) receiving isoniazid
discontinued treatment because of adverse events, … The RR of discontinuation
due to adverse events among patients treated with isoniazid vs pla-
cebo was … Rates of discontinuation because of adverse events were re-
ported in all 4 included RCTs, but 1 trial … Adverse events in adults with latent tuberculosis
infection receiving daily rifampicin or isoniazid:
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/s2xawZNAWVC5qgGyTT6r8m
October 01, 2015 - evidence on screening for iron
deficiency anemia in asymptomatic
children ages 6 to 24 months to
prevent adverse … Reported adverse events of
treatment with iron include limited
gastrointestinal symptoms, darkening
color … trial from 1991 that was not included
in the previous review found no
difference in overall or specific
adverse … events, including
gastrointestinal events.12
Estimate of Magnitude of Net Benefit
Overall, the USPSTF
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/gWJU-ZynehGyLBVYtDmMow
May 01, 2009 - Harms include
testing and follow-up for false-positive test results and adverse
effects from penicillin … 2003 through 31
July 2008 and used the search terms penicillin, pregnancy,
infant, newborn, fetus, adverse … Events after exposure
were compared with each
patient’s baseline period 183 d
before index date of study … attributed to oral route,
preselection if penicillin allergy was identified,
mislabeling as allergic events … Mentions risks of misdiagnosis, including
adverse penicillin reaction, stigma, and social
consequences
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/5P_7f2rbEquA-ZR-fJJfHK
April 27, 2021 - blood pressure monitoring offers the most evidence-
based risk information for future cardiovascular events … suggested that screening is not associated with any substantial short-
term quality of life changes or adverse … Seven studies
(n = 3505) reported minor adverse events such as sleep distur-
bance, pain/discomfort, … White-coat
hypertension and cardiovascular events:
a meta-analysis. … Cardiovascular events
and mortality in white coat hypertension:
a systematic review and meta-analysis