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321. Primary Care Interventions to Prevent Child Maltreatment: US Preventive Services Task Force Recommendaiton Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/PR7HUFdx2b_F9HvDFqz76L
     March 19, 2024 - • The Centers for Disease Control and Prevention also offers “Adverse Childhood Experiences (ACEs) … for Action: A Compilation of the Best Available Evidence,” a report on the best evidence to prevent adverse … reported higher (statistically nonsignificant) mortality rates in the intervention group.1,21 Fortunately, events … related to the in- tervention in either study.1,21 One trial reported miscarriage or ter- mination events … event (mainly clinical events associated with pregnancy and the infancy period) in the intervention

322. Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Systematic Evidence Review (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/3HxQuXnyqHpUKNqjB7hWBw
     September 01, 2005 - Medicine Volume 143 • Number 5 www.annals.org risk (2.21 [CI, 1.63 to 2.98]) for thromboembolic events … Table 6 also describes adverse effects. … to prevent breast cancer‡ 0.38 (0.17–0.54) 0.38 (0.17–0.54) 0.38 (0.17–0.54) Risk for thromboembolic events … effects Women using chemoprevention, n 33 (7.3–59) 412 (92–733) 2386 (532–4242) Cases of thrombotic events … Results also show sig- nificantly increased risks for thromboembolic events and, for tamoxifen, increased

323. Recommendation: Prevention of Acquisition of HIV: Preexposure Prophylaxis | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
     August 22, 2023 - events (primarily grade 1 or higher creatinine level elevation) (12 trials [n = 18,170]; RR, 1.43 [95% … events (12 trials [n = 18,300]; RR, 1.63 [95% CI, 1.26-2.11]; absolute risk difference, 1.95% [95% CI … 32 One trial (n = 5387) reported no differences between TAF/FTC and TDF/FTC in rates of any kidney adverse … events (1% vs 1%) or risk of fracture (2% vs 2%). 38 Two trials (n = 7786) reported no differences … that PrEP is associated with a small magnitude of harms, which include kidney and gastrointestinal adverse

324. S5Tzxonejd3Qzsoj-7Bq5P (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/s5tZxonEjD3qZsoj-7Bq5P
     May 01, 2014 - Even infrequent use increases the risk for serious adverse events by increasing risk-taking behaviors … Consistent 3 (adverse events) NA 0 0 NA NA NA � not applicable. … NA NA No studies assessed adverse events of the intervention. … Harms of Interventions We identified no studies that reported adverse events related to interventions … What are the adverse events of primary care behavioral counseling drug use interventions?

325. Screening for Asymptomatic Bacteriuria in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/3R9N4ojm9Sk7qk8ybD3LU6
     October 11, 2019 - The known harms associated with treatment include adverse effects of antibiotic use and changes to the … preterm birth.9 The presence of asymptomatic bacteriuria has not been shown to increase the risk of adverse … found adequate evidence of harms associated with treat- ment of asymptomatic bacteriuria, including adverse … In addition, there are newer concerns about antibi- otic use, such as antimicrobial resistance and adverse … events associ- ated with treatment of asymptomatic bacteriuria.

326. JAMA JATS (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/UA7cEG8wH4xh8-fr7Lfw9q
     September 18, 2018 - found few events in any group (2 trials [n = 6210]). … events between intervention and control groups. … Serious adverse events were uncommon and similar between groups.1 Adverse event rates were high in both … intervention and placebo groups by 12 months, with 80% to 96% of participants experiencing an adverse … The higher rate of adverse events in the medication groups resulted in higher dropout rates than in the

327. Recommendation: High Body Mass Index in Children and Adolescents: Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening
     June 18, 2024 - None of the trials found an increased risk of any adverse event or serious adverse events, including … More than 60% of youth taking liraglutide, semaglutide, or orlistat experienced gastrointestinal adverse … For example, in the largest trial of liraglutide, gastrointestinal adverse effects occurred in 65% of … effects). 1 , 10 Serious adverse effects were rare in all of the pharmacotherapy trials. … No evidence was available on adverse effects beyond 1 month after medication discontinuation or longer

328. JAMA (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/GcjfCZtGpACQMv2KScLbEu
     June 11, 2019 - b Include adverse maternal and infant outcomes associated with use of antiretroviral therapy. … event vs zidovudine monotherapy, but few women left the study because of adverse events Inconsistent … events than zido- vudine alone (21% vs 17%, P = .008). … events. … risk of an adverse outcome. N Engl J Med. 2002; 346(24):1863-1870. doi:10.1056/NEJMoa991159 75.

329. Archived: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
     April 11, 2016 - Treatment and Dosage The optimal dose of aspirin to prevent CVD events is not known. … Few fatal stroke events were reported in trials. … Initiating aspirin use during ages 50 to 59 years and continuing unless contraindicated by an adverse … Initiating aspirin use during ages 60 to 69 years and continuing unless contraindicated by an adverse … Aspirin for primary prevention of cardiovascular disease events.

330. Final Recommendation Statement: Prevention of Child Maltreatment: Primary Care Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/child-maltreatment-primary-care-interventions
     March 19, 2024 - The Centers for Disease Control and Prevention also offers “Adverse Childhood Experiences (ACEs) Prevention … for Action: A Compilation of the Best Available Evidence,” a report on the best evidence to prevent adverse … higher (statistically nonsignificant) mortality rates in the intervention group. 1 , 21 Fortunately, events … related to the intervention in either study. 1 , 21 One trial reported miscarriage or termination events … event (mainly clinical events associated with pregnancy and the infancy period) in the intervention

331. Archived: Obesity in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-june-2017
     June 20, 2017 - as mental health and psychological issues, asthma, obstructive sleep apnea, orthopedic problems, and adverse … Five trials found no adverse or serious adverse events in the intervention group. … Three fair-quality trials (n=779) found that gastrointestinal adverse effects were more common in the … intervention groups than in the placebo groups. 3 Gastrointestinal adverse effects were common among … Rates of discontinuation due to adverse effects were twice as common in the intervention group as in

332. Archived: Final Research Plan: Genital Herpes Infection: Serologic Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/genital-herpes-screening-november-2016
     August 06, 2015 - KQ 4: Reduced rates (or frequency) of subclinical HSV-2 viral shedding KQ 6: Treatment-related adverse … events (e.g., adverse drug reactions related to antiviral medications); psychosocial harms related to

333. Archived: Final Research Plan: Sexually Transmitted Infections: Behavioral Counseling | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan34/sexually-transmitted-infections-behavioral-counseling-september-2014
     May 15, 2013 - What adverse effects are associated with primary care behavioral counseling interventions to prevent … target populations (e.g., decrease in substance abuse/misuse among current drug users) KQ 4: Adverse … events Paradoxical increase in STI incidence or risky sexual behaviors or decrease in protective

334. Archived: Final Research Plan: Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors: Behavioral Counseling | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan17/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
     May 15, 2013 - What are the adverse effects of primary care–relevant behavioral counseling interventions for healthy … outcomes (physical activity, dietary intake or patterns), self-reported or objectively measured KQ 4: Adverse … requiring medical attention (e.g., nutritional deficiencies, musculoskeletal injuries, cardiovascular events

335. Recommendation: Iron Deficiency Anemia in Young Children: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-in-young-children-screening
     September 07, 2015 - evidence on screening for iron deficiency anemia in asymptomatic children ages 6 to 24 months to prevent adverse … Reported adverse events of treatment with iron include limited gastrointestinal symptoms, darkening color … trial from 1991 that was not included in the previous review found no difference in overall or specific adverse … events, including gastrointestinal events. 12 Estimate of Magnitude of Net Benefit Overall, the

336. Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for CVD Prevention in Adults With Cardiovascular Risk Factors: USPSTF Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/oo3XPmknWkhsBbAuYZQyQw
     November 24, 2020 - , mortality, or quality of life.11,16 Twelve of these trials reported cardiovascular events, and among … reviewed by the USPSTF, only 20 specifically reported on harms, and 8 of these specifically reported no adverse … events.11,16 Few trials reported details about the adverse events, but most were minor. … Serious ad- verse events were rare.11,16 There was no consistent evidence that behavioral counseling … Large replication stud- ies of interventions showing reductions in CVD events are urgently needed.

337. Final Recommendation Statement: Asymptomatic Bacteriuria in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/asymptomatic-bacteriuria-in-adults-screening
     September 24, 2019 - preterm birth. 9 The presence of asymptomatic bacteriuria has not been shown to increase the risk of adverse … In addition, there are newer concerns about antibiotic use, such as antimicrobial resistance and adverse … treatment in nonpregnant women 34 , 36 and 2 studies in older adults 32 , 35 reported on rates of adverse … events associated with treatment of asymptomatic bacteriuria. … The relationship between asymptomatic bacteriuria and adverse pregnancy outcomes is related to a combination

338. Archived: Lipid Disorders in Adults (Cholesterol, Dyslipidemia): Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2008
     December 30, 2013 - evidence that the harms from screening and treatment are small and include possible labeling and the adverse … Although the triglyceride level is a strong univariate predictor of coronary events, its association … with coronary heart disease events is reduced substantially by adjustment for other risk factors. … group receiving usual care, found no statistically significant reduction in coronary heart disease events … Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average

339. Tjdzc7Rzm3Wzcdhfc4Sjhq (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/TjDzC7rzm3WzCDHFC4sJhQ
     June 01, 2015 - events (47). … events (RR, 1.16 [CI, 1.11 to 1.23]) (28, 29). … No evidence on serious psychological or other adverse effects associated with a new diagnosis of diabetes … events versus placebo in 1 study (47), with no clear increased risk for serious adverse events. … B All-cause mortality: 2.2 vs. 3.8 events/1,000 person-years; HR 0.57 (95% CI 0.21 to 1.58) CV events

340. Archived: Evidence Summary: Hepatitis C Virus Infection: Screening, 2004 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/hepatitis-c-virus-infection-screening-2004
     March 08, 2004 - events. … Good Common adverse events with interferon-based therapy are self-limited influenza-like symptoms, … Withdrawals due to adverse events occurred in 14%-22% of patients on pegylated interferon plus ribavirin … adverse events from liver biopsy, and effects of diagnosing chronic HCV infection on quality of life … events in treatment-naive samples.