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  1. www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2008
    June 15, 2008 - USPSTF reviewed the evidence on early treatment of type 2 diabetes mellitus in preventing long-term adverse … Potential Harms of Screening and Treatment: Observational studies report no serious long-term adverse … No studies reported adverse effects of receiving a diagnosis of IFG or IGT, and no studies examined the … agents. 15 Angiotensin-converting enzyme inhibitors and statins have reasonably low levels of serious adverse … The relationship between glucose and incident cardiovascular events.
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-and-nicotine-use-prevention-in-children-and-adolescents-primary-care-interventions
    April 28, 2020 - however, most quit attempts fail, and about 80% will go on to smoke into adulthood. 36 Immediate adverse … of NRT found a greater number of headaches, cough, abnormal dreams, muscle pain, and patch-related adverseevents with NRT. 38 Bupropion carries a boxed warning for increased risk of suicidality in children … events, including suicidality, seizures, interaction with alcohol, cardiovascular events, sleepwalking … withdrew because of adverse events with bupropion. 14 Some studies reported more headaches, cough,
  3. JAMA (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/2DGd8AvVMTJwP3ttrPcnLL
    February 25, 2020 - NRT found a greater num- ber of headaches, cough, abnormal dreams, muscle pain, and patch- related adverseevents with NRT.38 Bupropion carries a boxed warn- ing for increased risk of suicidality in children … events, including suicidality, seizures, inter- action with alcohol, cardiovascular events, sleepwalking … on benefits be- cause its follow-up was less than 6 months.50 No difference in se- rious or severe adverse … withdrew because of adverse events with bupropion.14 Some stud- ies reported more headaches, cough,
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/SaASReVeD_fpHZQbeBZD5s
    October 01, 2016 - Although statins in middle-aged and older adults appear to be relatively safe and short-term adverseevents generally resolve with discontinuation of therapy, long-term adverse ef- fects of statins started … Long-term in- traindividual cholesterol variability: natural course and adverse im- pact on morbidity … psychosocial consequences such as anxiety, overdiagnosis, and others as identified in the literature) KQ 2: Adverse … function tests or creatine phosphokinase levels, and others as identified in the literature) KQ 6: Other adverse
  5. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - used low and moderate doses; under these conditions, statin use was not associated with serious adverse … Myalgia is a commonly reported adverse effect of statins, but placebo-controlled trial data do not support … prevention of CVD, statin therapy was not associated with an increased risk of withdrawal because of adverse … experiencing any serious adverse event. … elevated aminotransferase levels with statin use. 6 Evidence on the association between statin use and adverse
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-supplementation-to-prevent-cancer-and-cvd-counseling-and-preventive-medication
    June 15, 2003 - vitamin E supplementation for secondary prevention demonstrated a significant reduction in cardiac events … heavy smokers, in 2 RCTs. 14 , 25 Results from 4 RCTs demonstrate no reduced risk for cardiovascular events … Among cohort studies, 1 good-quality study reported a significant reduction in coronary events, 36 2 … The adverse effects of vitamin supplementation were not reported in most studies reviewed by the USPSTF … Vitamin E supplementation and cardiovascular events in high-risk patients.
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-supplementation-to-prevent-cancer-and-cvd-counseling-and-preventive-medication-2003
    June 15, 2003 - vitamin E supplementation for secondary prevention demonstrated a significant reduction in cardiac events … heavy smokers, in 2 RCTs. 14 , 25 Results from 4 RCTs demonstrate no reduced risk for cardiovascular events … Among cohort studies, 1 good-quality study reported a significant reduction in coronary events, 36 2 … The adverse effects of vitamin supplementation were not reported in most studies reviewed by the USPSTF … Vitamin E supplementation and cardiovascular events in high-risk patients.
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-in-older-adults-screening
    October 19, 2017 - due to labeling (psychological harms, insurance status, loss of driving privileges) KQ 5: Serious adverseevents (e.g., death, serious adverse drug reactions), adverse reactions from medications, unexpected
  9. www.uspreventiveservicestaskforce.org/uspstf/recommendation/impaired-visual-acuity-in-older-adults-screening-2016
    March 01, 2016 - antioxidant vitamins and mineral supplements is not associated with increased risk of most serious adverseevents. … with greater likelihood of withdrawal vs sham therapy; there were no differences in serious or other adverseevents, but estimates were imprecise. 1 , 4 , 6 , 7 Current Practice About half of US adults … event, serious adverse events, serious ocular events, or withdrawal due to adverse events. 1 Treatment
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/CW23r2jqogvTG2_-kBjRxH
    January 01, 2007 - in children/adolescents effective in delaying the onset and reducing the incidence of CHD-related events … of screening for dyslipidemia in identifying children/adolescents at increased risk of CHD-related events … incidence of adult dyslipidemia, and delaying the onset and reducing the incidence of CHD-related events … Drug treatment Information about adverse events was reported in 15 studies of statins,18, 19, 165, … There are no trials with long-term follow-up for adult 23 lipid outcomes or CHD-related events
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/8VDGX2azX2-s7FfxDeKMPN
    June 01, 2003 - • The adverse effects of beta-carotene on smokers have been observed primarily in those taking large … vitamin E supplementation for secondary prevention demonstrated a significant reduction in cardiac events … Among cohort studies, 1 good-quality study reported a significant reduction in coronary events,36 2 good-quality … Potential Harms of Vitamin Supplementation There are several known adverse effects caused by excessive … Vitamin E supplementation and cardiovascular events in high-risk patients.
  12. www.uspreventiveservicestaskforce.org/uspstf/recommendation/menopausal-hormone-therapy-preventive-medication-december-2017
    December 12, 2017 - individual characteristics that affect the likelihood of experiencing a specific therapy-associated adverse … to women at increased risk of breast cancer who do not have contraindications and are at low risk of adverse … findings from the Women’s Health Initiative (WHI) that hormone therapy use was associated with serious adverse … individual characteristics that affect the likelihood of experiencing a specific therapy-associated adverse … in women at increased risk of breast cancer who do not have contraindications and are at low risk of adverse
  13. www.uspreventiveservicestaskforce.org/uspstf/recommendation/high-cholesterol-other-lipid-abnormalities-screening-1996
    January 01, 1996 - due to effects of estrogen, 5 but women account for 49% of all CHD deaths in the U.S. 2 Clinical events … 3%. 20 High cholesterol (≥240 mg/dL) is also a risk factor in middle-aged women, but most coronary events … nonlipid risk factors, persons with cholesterol below 240 mg/dL account for the majority of all CHD events … New insights into prevention of plaque disruption and clinical events in coronary disease. … Review of dietary intervention studies: effect on coronary events and on total mortality.
  14. www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-in-adults-screening-2009
    December 15, 2009 - Also, information on the possible adverse effects and harms of depression care management programs is … events from antidepressant treatment in all adults. … effects of treatment of patients who are incorrectly identified as being depressed, and potential adverse … Harms of treatment include serious adverse effects of antidepressants, such as suicide-related events … For older adults, harms of treatment also include serious medical events, such as UGI bleeding.
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/KdQef_VDT2kmHDX4ddNWmR
    August 01, 2022 - isoniazid (RR, 1.50 [95% CI, 1.18-1.89]) and a greater risk of gastrointestinal adverse events (RR, 1.33 … Recent trials also reported on discontinuation due to adverse events. … There was a statistically nonsignificant increase in discontinu- ation due to adverse events in a meta-analysis … this was statistically significant in only 1 trial.9,28 Overall, study re- ports of gastrointestinal adverseAdverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/72-qtLK_m7urbSFT2yQZ2A
    June 01, 2023 - previously and using clinical judgment while considering risk factors, comorbid conditions, and life events … depression, prior episodes of depression or other mental health conditions, a history of trauma or adverse … life events, or a history of disease or illness
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3w8Wr9wwAyAqUJWmJo_bL-
    February 01, 2014 - Women us- ing tamoxifen and raloxifene had more thromboembolic events than women using placebo (tamoxifen … Coronary heart disease events and stroke were not increased in placebo-controlled trials, although women … Few studies described adverse effects. … In trials, tamoxifen and raloxifene increased thromboem- bolic events and tamoxifen increased endometrial … Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women.
  18. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/skin-cancer-screening-1
    January 07, 2021 - beyond 30 days) from screening, biopsy, or excision; including psychosocial harms and procedure-related adverseevents KQs 1, 2, 4: Non-skin location Risk reduction behaviors (e.g., skin self-examination
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/2VxcSta8ko2L_GC97XjZqm
    September 01, 2015 - balance of benefits and harms of screening for iron deficiency anemia in pregnant women to prevent adverse … assess the balance of benefits and harms of routine iron supplementation for pregnant women to prevent adverseadverse maternal health and birth outcomes Negative events, such as premature birth, low birth weight
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/falls-prevention-in-older-adults-interventions
    April 17, 2018 - Eight studies (n=4107) evaluating exercise interventions reported on harms; in general, adverse events … were minor. 8 , 10 The most common adverse events included pain or bruising related to exercise. … or severe adverse events, although ascertainment of adverse events was unclear. 8 One study on a single … psychological intervention reported no adverse events. 25 The remaining studies did not report on harms … or adverse events.

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