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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Y5p8ZXy2ydg_VZMUfxbJ-6
April 25, 2017 - Adverse perinatal
outcomes for the fetus and newborn include intrauterine growth restriction, low birth … Adverse peri-
natal outcomes for the fetus and newborn include intrauterine
growth restriction, low birth … include a history of eclampsia or preeclampsia
(particularly early-onset preeclampsia), a previous adverse … events. … studies of timing of delivery, trial evidence supports delivery
of the fetus to reduce the risk of adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/drug-use-illicit-screening
October 20, 2016 - Key Question 4a) and health outcomes (Key Question 4b) and whether these interventions result in any adverse … events (Key Question 5).
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www.uspreventiveservicestaskforce.org/uspstf/document/treatment-evidence-summary/gestational-diabetes-mellitus-screening-january-2014
May 28, 2013 - The more immediate risk for adverse outcomes of GDM in the mother and child is less well-established. … Evidence was insufficient for birth injury due to imprecision (low number of events and participants … There were no differences in perinatal death, although the number of events was extremely low (<0.5%) … This is probably due to the infrequent occurrence of these events and a resulting lack of power across … Hyperglycemia and adverse pregnancy outcomes. N Engl J Med . 2008;358:1991-2002.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kAg43FLUnTjCU5ZNaaHQtW
March 01, 2016 - For rare
events, meta-analyses are needed that include only
children and adolescents with MDD and focus … reported on harms and found no ap-
parent differences in harms-related, suicide-related, or
psychiatric adverse … events between the CBT and pla-
cebo groups (10). … the data
are limited, the USPSTF concludes that the evidence on
the frequency of medication-related adverse … events in
adolescents is adequate to estimate that the magnitude
of harms of pharmacotherapy is small
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-screening-1996
January 01, 1996 - 29 and others have proposed modified criteria with lower thresholds as more sensitive predictors of adverse … were found not to have diabetes on further evaluation. 47 Even a true-positive diagnosis could have adverse … those with NIDDM, 81 and there was no correlation between cerebrovascular and peripheral vascular events … The high risk associated with GDM in earlier cohorts primarily reflects adverse outcomes in women who … The significance of one abnormal glucose tolerance test value on adverse outcome in pregnancy.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ghbfx9e3A6jQEqVW26y8Jv
March 09, 2021 - Less than one-third of patients
in most studies experienced treatment-related adverse events. … Adverse events reported in ≥10% of patients included
pulmonary events (eg, air leak, pleural effusion … intervention, missing data, and
sources of survival outcomes often
lacking; potential selective reporting
of adverse … Adverse
events were experienced by most patients, but most were of mild or
moderate severity. … Adverse events reported in ≥10% of patients
included were pulmonary events (eg, cough, dyspnea, pneumonitis
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary11/carotid-artery-stenosis-screening-december-2007
December 15, 2007 - Good
Kresowik, 2004 44
4093
Not reported
Combined events 3.8%
The combined … caused
18 events prevented
Angiography confirmation
55 events caused
106 events prevented … MRA confirmation
23 events caused
217 events prevented
NNS to prevent 1 stroke over … The first of these curved arrows ends at an oval labeled "Adverse effects of screening." … The second arrow ends at an oval labeled "Adverse effects of CEA."
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/YSj5xRQc9DroH8gpUYsoFA
December 01, 2007 - Adverse effects
of screening
Asymptomatic
adults
Reduced
number of
strokes and deaths
Adverse … The events in the carotid endarterectomy group of
the RCTs occurred earlier than those in the medical … caused 18 events prevented
Angiography confirmation 55 events caused 106 events prevented
MRA confirmation … 23 events prevented 217 events prevented
NNS to prevent 1 stroke over 5 years
No confirmatory test … Events caused � prevented 5556
Angiography confirmation Events caused � prevented 944
MRA confirmation
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/s9Hht_QpMB4gQg26rTpcaN
November 01, 2013 - However, total serious
adverse events did not seem to differ for these medications
across trials with … Three small trials reporting zero adverse events are
not reflected in these estimates (111, 112, 123) … The definitions of seri-
ous adverse events were not commonly described in the
included studies. … Observational studies suggest that brady-
cardia and adverse events related to it (for example, fall … Meta-analyses of effects of AChEIs and memantine on withdrawals due to adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
July 26, 2022 - effectiveness of behavioral counseling interventions on all-cause mortality, CVD-related mortality, CVD events … myocardial infarction or stroke), or quality of life. 1 , 38 In studies, CVD-related fatal and nonfatal events … statistically significant differences reported between intervention participants and control groups on any adverse … events, serious adverse events, musculoskeletal injuries, or falls. 1 , 38
Response to Public Comment … Data directly assessing the effect of counseling interventions on CVD-related events and mortality are
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening
June 24, 2025 - partner violence (IPV) and caregiver abuse of older and vulnerable adults can cause acute and long-term adverse … events were reported by participants, clinicians, or research staff; however, it is not clear whether … adverse events were prespecified or how they were monitored. 18
Benefits of Interventions
Key Question … The RCT assessing behavioral counseling during prenatal care found a reduction in both IPV and some adverse … Overall, evidence on the adverse effects of interventions was limited.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 28, 2021 - Peto odds ratio method, 23 as well as pooled analyses including and excluding studies that had no events … Does the effectiveness of aspirin for reducing adverse health outcomes vary by subpopulations defined … Few trials reported these events, however, and pooled estimates were not possible to compute. … Excluded 3 studies with 0 events in both groups. … ratio; SGA/IUGR, small for gestational age/intrauterine growth restriction. a Studies that reported no events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kHDoNjsfLx9SyKGD5n2ufL
January 01, 2020 - For adverse events, harms that could be related to
a breastfeeding intervention (eg, feeling criticized … The data on health outcomes (KQ1) and adverse
events (KQ3) did not allow for pooled analyses and so were … Are there adverse events associated with interventions to promote and support breastfeeding? … Are there adverse events associated with interven-
tions to promote and support breastfeeding? … Only 2 trials36,43 reported adverse events related to a breast-
feeding intervention.
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/depression-in-adults-screening
January 26, 2016 - previously and using clinical judgment in consideration of risk factors, comorbid conditions, and life events … an individual may include emotional suffering, reduced quality of personal relationships, possible adverse … and Treatment
General Adult Population and Older Adults
One trial in general adults reported no adverse … events attributable to screening in a subset of participants with newly-identified depression; 24 none … The 2009 USPSTF review found 7 studies that compared suicide-related events in adults who received SSRIs
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/hypertensive-disorders-pregnancy-screening
September 19, 2023 - disorders of pregnancy are among the leading causes of maternal morbidity and mortality as well as adverse … attributed to hypertensive disorders of pregnancy (65%) occur in the 6 weeks following delivery. 6 Adverse … events. 1 , 31 In addition, screening and monitoring by various health care providers (eg, nurse midwives … , ongoing monitoring and evidence-based management of the condition is needed to reduce the risk of adverse … Racial disparities in adverse pregnancy outcomes and psychosocial stress.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review49/hepatitis-c-screening-2013
November 15, 2012 - ) in HCV-infected patients with compensated cirrhosis reported no deaths and a 1.1% rate of serious adverse … events (primarily bleeding and severe pain). … events, most commonly bleeding or severe pain, with no deaths 48 . … Benefits and adverse effects of hepatitis C screening: early results of a screening program. … events in 1.1%, including 0.6% serious bleeding episodes and 0.3% severe pain, with no deaths.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pKa4_DYwzuyD6RDgYzLMbo
August 22, 2018 - Intimate partner violence (IPV), elder abuse, and abuse of vulnerable adults are
common and result in adverse … physi-
cal and mental health as well as adverse social consequences
(eg, homelessness).1 IPV refers … The second RCT (n = 344) stated that partici-
pants, clinicians, or research staff reported no adverse … events; how-
ever, it is not clear whether adverse events were prespecified or how
they were monitored … events related to participation were reported
by women in either group.37 Three other RCTs (n = 1031
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/9Tse2TwVFQgYb-aNCq4Ngv
September 04, 2018 - During this same period, in pregnant
women infected with syphilis, the incidence of all adverse out- … -
lar, no studies were found that addressed the risk of the Jarisch-
Herxheimer reaction or serious adverse … events in women with
a history of penicillin allergy. … Untreated maternal syphilis
and adverse outcomes of pregnancy: a systematic
review and meta-analysis. … Reported estimates of adverse pregnancy
outcomes among women with and without syphilis:
a systematic
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/BnHj53HwgSBNXMvnyavxfS
January 26, 2016 - an individual may include emotional
suffering, reduced quality of personal relationships, possible
adverse … Screening and Treatment
General Adult Population and Older Adults
One trial in general adults reported no adverse … events attribut-
able to screening in a subset of participants with newly identified
depression24; none … The 2009 USPSTF review found 7 studies that compared
suicide-related events in adults who received SSRIs … trial, which focused on the effects of screening alone in post-
partum women, specifically reported on adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication
August 01, 2023 - defects with supplementation and no consistent evidence of harms such as multiple gestation, maternal adverse … Several external events of importance were cited to explain differences by period: the introduction of … recall
No new evidence
NA
NA
2a: Harms associated with folic acid supplements: other adverse … events in women
1 RCT; n = 4862
Increased risk for weight gain, diarrhea, constipation; reduced