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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mx2Ko29RH46mTYb36f-UBe
June 20, 2023 - events, even if they have proven
benefits. … events. … Evidence demonstrated an increase in
nonserious harms (defined as any adverse events and withdrawals … due to adverse events). … Serious adverse events were rare and data
were insufficient to determine whether pharmacotherapy
increased
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary13/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-behavioral-counseling
December 07, 2010 - Key Question 4: Harms
Adverse effects were rarely noted in physical activity counseling trials. … We found no studies designed to assess the adverse effects of dietary counseling or the adverse effects … None of the healthful diet counseling trials reported specific adverse events. … However, the absolute risk for serious cardiac events related to physical activity seems very small. … events not reported in trials
Good
Good
No specific examination of adverse effects; however, 2
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary27/healthy-diet-and-physical-activity-counseling-for-cvd-prevention-in-adults
December 15, 2010 - Key Question 4: Harms
Adverse effects were rarely noted in physical activity counseling trials. … We found no studies designed to assess the adverse effects of dietary counseling or the adverse effects … None of the healthful diet counseling trials reported specific adverse events.
… However, the absolute risk for serious cardiac events related to physical activity seems very small. … events not reported in trials
Good
Good
No specific examination of adverse effects
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary13/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-behavioral-counseling-2012
December 07, 2010 - Key Question 4: Harms
Adverse effects were rarely noted in physical activity counseling trials. … We found no studies designed to assess the adverse effects of dietary counseling or the adverse effects … None of the healthful diet counseling trials reported specific adverse events. … However, the absolute risk for serious cardiac events related to physical activity seems very small. … events not reported in trials
Good
Good
No specific examination of adverse effects; however, 2
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary27/healthy-diet-and-physical-activity-counseling-for-cvd-prevention-in-adults-2012
December 15, 2010 - Key Question 4: Harms
Adverse effects were rarely noted in physical activity counseling trials. … We found no studies designed to assess the adverse effects of dietary counseling or the adverse effects … None of the healthful diet counseling trials reported specific adverse events.
… However, the absolute risk for serious cardiac events related to physical activity seems very small. … events not reported in trials
Good
Good
No specific examination of adverse effects
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-d-deficiency-screening-november-2014
November 24, 2014 - events, hypercalcemia, kidney stones, or gastrointestinal symptoms. … However, it is unclear if low 25-(OH)D levels are associated with adverse clinical outcomes in these … The USPSTF identified 24 studies 1 , 2 that reported on the adverse effects of vitamin D treatment; … however, most trials were not designed to assess harms, and reporting of adverse events was generally … No significant difference in rates of serious adverse events or withdrawals due to adverse events was
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/impaired-visual-acuity-in-older-adults-screening
March 01, 2016 - use vs placebo in risk of any adverse events (93% vs 89%; RR, 1.05; 95% CI, 0.97–1.13), serious adverse … events (31% vs 30%; RR, 1.04; 95% CI, 0.72–1.49), or serious ocular adverse events (8.2% vs 7.0%; RR … events, but estimates for those outcomes were imprecise. … events in participants taking zinc vs placebo. … No increase in risk of systemic hypertension or arterial thromboembolic events.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/impaired-visual-acuity-in-older-adults-screening-2016
March 01, 2016 - use vs placebo in risk of any adverse events (93% vs 89%; RR, 1.05; 95% CI, 0.97–1.13), serious adverse … events (31% vs 30%; RR, 1.04; 95% CI, 0.72–1.49), or serious ocular adverse events (8.2% vs 7.0%; RR … events, but estimates for those outcomes were imprecise. … events in participants taking zinc vs placebo. … No increase in risk of systemic hypertension or arterial thromboembolic events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/poDYcagnw7SqKNNbrFt_CV
June 11, 2019 - Limited data suggest that PrEP
use is not associated with significant adverse events in adolescents
but … There
was no clear difference in risk of kidney adverse events when trials
were stratified according … of serious renal events or with-
drawals due to renal events.31,32 Six trials41,42,55-58 evaluated
whether … renal adverse events while using PrEP were persistent. … The risk of gastrointes-
tinal adverse events increased with both tenofovir disoproxil fuma-
rate monotherapy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mfyVxbhXeqBjMR6jLJcLr4
May 24, 2022 - or other serious
adverse events, although no statistically significant differences
were reported.24,27,44,66 … events and cardiovascular events were infre-
quent and occurred in similar proportions of patients randomized … VECAT (n = 1193), the largest trial other than AREDS and
AREDS2, reported no serious adverse events with … vitamin E or pla-
cebo, and no differences in risk of withdrawal due to adverse events
or specific adverse … but did not
indicate increased risk of serious adverse events or withdrawal due
to adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary39/obesity-in-children-and-adolescents-screening-2010
January 15, 2010 - , any serious adverse event, or discontinuation caused by adverse events. … In the large 12-month sibutramine trial, serious adverse events were reported by 2.7% of patients in … Weight-management programs for which pre-specified adverse events that resulted in death, hospitalization … No minimum follow-up is required for serious (ie, requiring urgent medical care) adverse events (KQ3) … For trials that were not included for KQ1 or KQ2, outcomes were limited to serious adverse events such
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/hbSopN6uA9u-4EQuKtRGDP
October 01, 2011 - events
Context
Experts recommend that primary care clinicians offer
obese adults interventions that … events (Table 2) (22, 83,
102). … No studies re-
ported serious adverse effects. … Summary of Medication Harms
Adverse Events Trials in
Meta-analysis,
Additional
Trials, n, n
Meta-analysis … Meridia (sibutramine): market with-
drawal due to risk for serious cardiovascular events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VKGPkVjto7K4yfUHBKEHBA
January 01, 2025 - of findings from the
Women’s Health Initiative that hormone therapy use is associated with serious adverse … findings from the Women’s Health
Initiative (WHI) that hormone therapy use was associated with serious
adverse … individual char-
acteristics that affect the likelihood of experiencing a specific therapy-
associated adverse … in women at
increased risk of breast cancer who do not have contraindications
and are at low risk of adverse … individual characteristics
that affect the likelihood of experiencing a specific therapy-associated adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/RPB3rmcS9CK_eXPdzXSxZg
July 01, 2010 - Bisphosphonates are not con
sistently associated with serious adverse events; raloxifene and es
trogen … increase thromboembolic events; and estrogen causes addi
tional adverse events. … no differences
with placebo in rates of serious gastrointestinal adverse events
(107, 108) or withdrawals … Upper gastrointestinal adverse events
and cyclical etidronate. Am J Med. 1997;103:462-7. … Adverse Health Outcomes from Studies, by Medication
Adverse Outcome Evidence
Bisphosphonates
Withdrawals
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/genital-herpes-serologic-screening
July 08, 2021 - KQ 4: Reduced rates (or frequency) of subclinical HSV-2 viral shedding
KQ 6: Treatment-related adverse … events (e.g., adverse drug reactions related to antiviral medications); psychosocial harms related to
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VwvmgA5bLZZJhK6YSqRonU
November 01, 2022 - Adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular … events, type 2 diabetes, cognitive impairment, decreased quality of life, and motor vehicle crashes
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4zmYnqJXLv8g4LzLrrDDrm
December 01, 2014 - effectiveness
of low-dose aspirin in preventing preeclampsia in women at in-
creased risk and in decreasing adverse … events. … Assessment of Risk for Adverse Effects
Low-dose aspirin use in women at increased risk for
preeclampsia … Eighteen trials reported on the outcome of perinatal
mortality (with 4 smaller studies reporting no events … Seven trials reported adverse events; however, most
were determined to be unrelated to treatment.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/peripheral-arterial-disease-pad-screening
August 08, 2005 - group; however, the study did not address the impact of interventions on PAD or cardiovascular disease events … intermittent claudication. 14
Potential harms of screening include false-positive results, labeling, and the adverse … events associated with an angiographic workup, including contrast-related events, arterial perforations … , hematomas, thromboses, and distal embolizations; the harms of treatment include the adverse events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/peripheral-arterial-disease-pad-screening-2005
August 08, 2005 - group; however, the study did not address the impact of interventions on PAD or cardiovascular disease events … intermittent claudication. 14
Potential harms of screening include false-positive results, labeling, and the adverse … events associated with an angiographic workup, including contrast-related events, arterial perforations … , hematomas, thromboses, and distal embolizations; the harms of treatment include the adverse events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening
June 15, 2008 - USPSTF reviewed the evidence on early treatment of type 2 diabetes mellitus in preventing long-term adverse … Potential Harms of Screening and Treatment: Observational studies report no serious long-term adverse … No studies reported adverse effects of receiving a diagnosis of IFG or IGT, and no studies examined the … agents. 15 Angiotensin-converting enzyme inhibitors and statins have reasonably low levels of serious adverse … The relationship between glucose and incident cardiovascular events.