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www.uspreventiveservicestaskforce.org/uspstf/recommendation/child-maltreatment-primary-care-interventions
March 19, 2024 - The Centers for Disease Control and Prevention also offers “Adverse Childhood Experiences (ACEs) Prevention … for Action: A Compilation of the Best Available Evidence,” a report on the best evidence to prevent adverse … higher (statistically nonsignificant) mortality rates in the intervention group. 1 , 21 Fortunately, events … related to the intervention in either study. 1 , 21 One trial reported miscarriage or termination events … event (mainly clinical events associated with pregnancy and the infancy period) in the intervention
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/k_QR3hvh2jVSPPLu6Q6m6r
November 13, 2022 - events. … Statin therapy was not significantly associated with
increased risk of serious adverse events (RR, 0.97 … to 1.26%]) (eFigure 9 in the Supple-
ment), serious adverse events (10 trials, n = 55 419; RR, 0.97 … events, serious adverse events, cancer, or el-
evated liver enzyme levels vs placebo or no statin therapy … Statin safety and associated adverse
events: a scientific statement from the American
Heart Association
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/skin-cancer-screening
March 25, 2021 - beyond 30 days) from screening, biopsy, or excision, including psychosocial harms and procedure-related adverse … events
KQs 1, 2, 4:
Non-skin location
Risk reduction behaviors (e.g., skin self-examination
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary25/screening-for-abnormal-blood-glucose-and-type-2-diabetes-october-2015
April 13, 2015 - 1.73 [CI, 1.57 to 1.92]), and valsartan was associated with increased risk for hypotension-related adverse … events versus placebo in 1 study, 47 with no clear increased risk for serious adverse events. … trials were not designed or powered to specifically assess the risk for serious but uncommon or rare adverse … No evidence on serious psychological or other adverse effects associated with a new diagnosis of diabetes … CV events: 22.9 vs. 22.0 events/1,000 person-years; HR, 1.04 (95% CI, 0.72 to 1.51)
Fair
Pharmacologic
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
September 06, 2016 - Rates of discontinuations because of adverse events were 13.8% (isoniazid) and 3.4% (rifampin) 94 ; 5.6% … Similar rates of gastrointestinal adverse events were reported among the 3 studies; various other harms … Rates of discontinuation because of adverse events were 5.2% in the rifapentine plus isoniazid group … and 4.1% in the isoniazid-only group.The RR of treatment discontinuation because of adverse events for … Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/We5A-uCMvX5qYeFukGgqks
March 01, 2004 - events. … Good Common adverse events with
intolerance to treatment) Well-designed interferon-based therapy are … Withdrawals due to adverse
events occurred in 14%–22% of
patients on pegylated interferon
plus ribavirin … adverse events from liver biopsy, and effects of
diagnosing chronic HCV infection on quality
of life … events in treatment-naive samples.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
August 23, 2022 - On average, men experience CVD events earlier in life compared with women. … On average, men experience CVD events earlier in life compared with women. … analyses of trial data, statin therapy was not associated with increased risk of study withdrawal due to adverse … events or serious adverse events. 13 , 31 Although observational studies have reported an association … Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan6/high-blood-pressure-in-adults-screening-monitoring-october-2015
September 15, 2013 - How well do home and ambulatory blood pressure monitoring methods predict cardiovascular events compared … What confirmation protocol characteristics define the best prediction of cardiovascular events? … Which methods and associated protocols best predict cardiovascular events? … What are the adverse effects of screening for high blood pressure in adults? … of means)
KQ 3a: Measures of association of blood pressure and fatal or nonfatal cardiovascular events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study/aspirin-to-prevent-cardiovascular-disease-preventive-medication
April 26, 2022 - fatal CVD events resulting from nonfatal CVD events that were prevented prior to stopping aspirin. … observed in the aspirin primary prevention trials, but analyses by others have suggested there is no adverse … Net QALY assessments showed strong adverse influence from small disutilities associated with aspirin … Myocardial infarction and ischemic stroke events are nonfatal. … Net events prevented are defined by the net of benefit and harm events, or (nonfatal CVD events + CVD
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTJ_Zj3TAkhx45wWUDtNyt
May 01, 2021 - On
average, men experience CVD events earlier in life compared with
women. … Clinicians should recognize that pre-
dictions of 10-year CVD events using the Pooled Cohort Equations … analyses of
trial data, statin therapy was not associated with increased risk
of study withdrawal due to adverse … events or serious adverse
events.13,31 Although observational studies have reported an asso-
ciation … Rosuvastatin to prevent
vascular events in men and women with elevated
C-reactive protein.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan104/skin-cancer-screening-july-2016
July 17, 2014 - from screening, biopsy, or excision, including overdiagnosis, psychosocial harms, or procedure-related adverse … events
KQ 3: Sensitivity, specificity, positive predictive value, false-positive results, false-negative
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nop5YpEpMybx_oNPKC76-X
July 11, 2017 - Among 14 trials of
behavioral interventions that reported on adverse events, none re-
ported any serious … adverse events. … Behavioral Counseling Interventions
Of the 88 trials reviewed by the USPSTF, 14 specifically reported on
adverse … events.3 No trials reported any serious adverse events re-
lated to the counseling intervention. … car-
diovascular events.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-and-ovarian-cancer-brca-testing-screening-2005
September 15, 2005 - All trials indicated increased risk (2.21 [CI, 1.63 to 2.98]) for thromboembolic events, including pulmonary … Table 6 also describes adverse effects. … Results also show significantly increased risks for thromboembolic events and, for tamoxifen, increased … breast cancer ***
0.38 (0.17-0.54)
0.38 (0.17-0.54)
0.38 (0.17-0.54)
Risk for thromboembolic events … using chemoprevention, n
33 (7.3-59)
412 (92-733)
2,386 (532-4242)
Cases of thrombotic events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-adults-interventions
September 18, 2018 - found few events in any group (2 trials [n = 6210]). … Overall, the trials showed no serious harms, and most trials observed no difference in the rate of adverse … events between intervention and control groups. … Serious adverse events were uncommon and similar between groups. 1 Adverse event rates were high in … The higher rate of adverse events in the medication groups resulted in higher dropout rates than in the
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/perinatal-depression-interventions-to-prevent
June 01, 2023 - intensive care unit admission
Serious harms reported in trials of treatment benefit
Withdrawals due to adverse … events in trials of treatment benefit
KQ 1: Maternal behavioral intermediate outcomes (e.g.,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/h-w99jVsodSL33kV2h2_qW
April 17, 2018 - Eight studies (n = 4107) evaluat-
ing exercise interventions reported on harms; in general, adverse … events were minor.8,10 The most common adverse events included
pain or bruising related to exercise. … or severe adverse events, although ascertain-
ment of adverse events was unclear.8 One study on a single … psy-
chological intervention reported no adverse events.25 The remain-
ing studies did not report on … harms or adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2001
March 14, 2014 - trials, cholesterol-lowering drug treatment for 5 to 7 years decreased risk of coronary heart disease events … Potential Adverse Effects of Screening
Studies of adverse effects of screening are limited but have … not found adverse psychological effects (i.e., labeling) in patients identified with abnormal lipids … hyperlipidemia earlier than selective screening, whether this will lead to important reductions in coronary events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/aJ-xmGLsKqLQbQsBqodKZ5
January 01, 2001 - trials, cholesterol-
lowering drug treatment for 5 to 7 years decreased risk
of coronary heart disease events … Potential Adverse Effects of Screening
Studies of adverse effects of screening are limited but
have … not found adverse psychological effects (i.e., label-
ing) in patients identified with abnormal lipids … lipidemia earlier than selective screening, whether this
will lead to important reductions in coronary events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/genital-herpes-serologic-screening
December 02, 2021 - KQ 4: Reduced rates (or frequency) of subclinical HSV-2 viral shedding
KQ 6: Treatment-related adverse … events (e.g., adverse drug reactions related to antiviral medications); psychosocial harms related to
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/NZ_RQWxMMR8Vym-yJuqru-
May 23, 2019 - change, increased physical activity, and smoking
cessation are important behavioral steps to reduce adverse … health events. … Statins also have
low rates of serious adverse effects (132, 133). … Number Needed To Screen for Diabetes To Prevent One Adverse Event*
Prevalence of
Undiagnosed
Diabetes … Therapeutics
Treatment
Noninsulin-dependent diabetes
Mass screening
Labeling
Hypoglycemia
Adverse effects