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www.uspreventiveservicestaskforce.org/home/getfilebytoken/oo3XPmknWkhsBbAuYZQyQw
November 24, 2020 - , mortality, or quality of life.11,16 Twelve of these
trials reported cardiovascular events, and among … reviewed by the USPSTF, only 20 specifically reported
on harms, and 8 of these specifically reported no adverse … events.11,16
Few trials reported details about the adverse events, but most
were minor. … Serious ad-
verse events were rare.11,16 There was no consistent evidence that
behavioral counseling … Large replication stud-
ies of interventions showing reductions in CVD events are
urgently needed.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/genital-herpes-screening-november-2016
August 06, 2015 - KQ 4: Reduced rates (or frequency) of subclinical HSV-2 viral shedding
KQ 6: Treatment-related adverse … events (e.g., adverse drug reactions related to antiviral medications); psychosocial harms related to
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan34/sexually-transmitted-infections-behavioral-counseling-september-2014
May 15, 2013 - What adverse effects are associated with primary care behavioral counseling interventions to prevent … target populations (e.g., decrease in substance abuse/misuse among current drug users)
KQ 4: Adverse … events
Paradoxical increase in STI incidence or risky sexual behaviors or decrease in protective
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan17/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
May 15, 2013 - What are the adverse effects of primary care–relevant behavioral counseling interventions for healthy … outcomes (physical activity, dietary intake or patterns), self-reported or objectively measured
KQ 4: Adverse … requiring medical attention (e.g., nutritional deficiencies, musculoskeletal injuries, cardiovascular events
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/child-maltreatment-primary-care-interventions
March 19, 2024 - The Centers for Disease Control and Prevention also offers “Adverse Childhood Experiences (ACEs) Prevention … for Action: A Compilation of the Best Available Evidence,” a report on the best evidence to prevent adverse … higher (statistically nonsignificant) mortality rates in the intervention group. 1 , 21 Fortunately, events … related to the intervention in either study. 1 , 21 One trial reported miscarriage or termination events … event (mainly clinical events associated with pregnancy and the infancy period) in the intervention
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-june-2017
June 20, 2017 - as mental health and psychological issues, asthma, obstructive sleep apnea, orthopedic problems, and adverse … Five trials found no adverse or serious adverse events in the intervention group. … Three fair-quality trials (n=779) found that gastrointestinal adverse effects were more common in the … intervention groups than in the placebo groups. 3 Gastrointestinal adverse effects were common among … Rates of discontinuation due to adverse effects were twice as common in the intervention group as in
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/asymptomatic-bacteriuria-in-adults-screening
September 24, 2019 - preterm birth. 9
The presence of asymptomatic bacteriuria has not been shown to increase the risk of adverse … In addition, there are newer concerns about antibiotic use, such as antimicrobial resistance and adverse … treatment in nonpregnant women 34 , 36 and 2 studies in older adults 32 , 35 reported on rates of adverse … events associated with treatment of asymptomatic bacteriuria. … The relationship between asymptomatic bacteriuria and adverse pregnancy outcomes is related to a combination
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/GcjfCZtGpACQMv2KScLbEu
June 11, 2019 - b Include adverse maternal and infant outcomes associated with use of
antiretroviral therapy. … event vs zidovudine
monotherapy, but few women left the study because of
adverse events
Inconsistent … events than zido-
vudine alone (21% vs 17%, P = .008). … events. … risk of an adverse outcome. N Engl J Med. 2002;
346(24):1863-1870. doi:10.1056/NEJMoa991159
75.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/by8VJVre6h6BmadrGxaFMM
April 01, 2016 - Treatment and Dosage
The optimal dose of aspirin to prevent CVD events
is not known. … Few fatal stroke events were
reported in trials. … Initiating aspirin use during ages 50 to 59 years
and continuing unless contraindicated by an adverse … Initiating aspirin use during ages 60 to 69 years and
continuing unless contraindicated by an adverse … Aspirin
for primary prevention of cardiovascular disease events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-prophylaxis-myocardial-infarction-preventive-medication-1996
January 01, 1996 - This represents an absolute risk reduction of less than two events per thousand individuals per year. … been proposed for persons without neurologic symptoms who are at increased risk for thromboembolic events … in middle-aged and older men whose risks of a first MI are sufficiently high to warrant the possible adverse … should be made on an individual basis after the benefits of decreased risk of ischemic cardiovascular events … Nyman I, Larsson H, Wallentin L Prevention of serious cardiac events by low-dose aspirin in patients
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary94/syphilis-infection-in-pregnancy-screening-2009
May 15, 2009 - Harms include testing and follow-up for false-positive test results and adverse effects from penicillin … , code; Current Procedural Terminology code; or procedural code for anaphylactic shock, unspecified adverse … Events after exposure were compared with each patient's baseline period 183 d before index date of study … attributed to oral route, preselection if penicillin allergy was identified, mislabeling as allergic events … Mentions risks of misdiagnosis, including adverse penicillin reaction, stigma, and social consequences
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/hepatitis-c-virus-infection-screening-2004
March 08, 2004 - events. … Good
Common adverse events with interferon-based therapy are self-limited influenza-like symptoms, … Withdrawals due to adverse events occurred in 14%-22% of patients on pegylated interferon plus ribavirin … adverse events from liver biopsy, and effects of diagnosing chronic HCV infection on quality of life … events in treatment-naive samples.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/child-maltreatment-primary-care-interventions
March 19, 2024 - families or worsening of inequities (eTable 51 in the JAMA Supplement). 33 , 34 , 51-53 In 1 study, adverse … found that the child maltreatment intervention was associated with slightly increased risk of a serious adverse … (43% vs 38%; calculated RR, 1.15 [95% CI, 1.03-1.25]). 33 However, no adverse events were judged to … The numbers of specific adverse events (miscarriages/terminations, stillbirth/neonatal death/infant death … Two studies did not report statistically significant adverse events between study groups.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/MLeu_yFpPwzcZwKG6fw5ZY
April 26, 2022 - In contrast, the reduction of these 2 events was more
evenly balanced for women. … fatal CVD events resulting from nonfatal CVD events that were
prevented prior to stopping aspirin. … observed in the aspirin primary
prevention trials, but analyses by others have suggested there is
no adverse … Net QALY assess-
ments showed strong adverse influence from small disutilities as-
sociated with aspirin … Effect of aspirin on
cardiovascular events and bleeding in the healthy
elderly.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/abdominal-aortic-aneurysm-screening
December 10, 2019 - Techniques for Aortic Aneurysm Repair [EUROSTAR]) ( Table 4 ). 40 , 71
Only the ADAM trial reported adverse … reported in the 2 trials of EVAR. 29 , 69 In the CAESAR trial, the percentage of patients with any adverse … at 3- to 4-year follow-up. 40 , 71
Eight short-term drug trials (n = 1598) reported high rates of adverse … In the CAESAR trial, the early intervention group had a higher percentage of patients with any adverse … Pharmacotherapy vs placebo
8 (1598)
With the exception of the 2 propranolol trials reporting high adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-july-2016
August 09, 2016 - generally well tolerated in children and adolescents with familial hypercholesterolemia, with transient adverse … is generally asymptomatic in childhood and adolescence and is rarely associated with cardiovascular events … The adverse effects of long-term use of lipid-lowering pharmacotherapy and lifestyle modification (including … Some experts recommend starting statin use at age 8 or 10 years; others, concerned with adverse effects … Cardiovascular events rarely occur in the first 2 decades of life, typically taking place during the
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-pregnancy-screening-september-2018
September 04, 2018 - association of implementing a screening program with the incidence of congenital syphilis and other adverse … During this same period, in pregnant women infected with syphilis, the incidence of all adverse outcomes … events in women with a history of penicillin allergy. … Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis. … Reported estimates of adverse pregnancy outcomes among women with and without syphilis: a systematic
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/XW6XUe2wRmkM-6Rrbn_462
February 01, 2023 - Eligible harms
outcomes for intervention studies (KQ 6) included medication-related adverse events … events, which would fall
within this review’s scope. … events between groups (headache, nausea).81
It was unclear if adverse events
were prespecified. … Reactions"] OR [mh "Long Term Adverse
Effects"] OR [mh "Patient Harm"] OR harm OR harms OR "adverse … events (e.g.,
adverse drug reactions related to antiviral
medications); psychosocial harms related
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening
January 14, 2025 - A pooled analysis of 21 RCTs found no significant difference in serious adverse events. … One trial reported a statistically significant increase in gastrointestinal adverse events in the treatment … of 26 RCTs (representing 27 comparisons) found no significantly increased risk of gastrointestinal adverse … events in participants taking bisphosphonates compared with those taking placebo. … events (5 RCTs) or upper gastrointestinal tract adverse events (4 trials), although the CIs were wide
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DMDPeSf_nEUM-HrVrX6c7U
June 20, 2017 - mental health and
psychological issues, asthma, obstructive sleep apnea, orthopedic problems, and adverse … Obesity in childhood and adolescence may continue into
adulthood and lead to adverse cardiovascular … Obesity in childhood and adolescence may continue into
adulthood and lead to adverse cardiovascular … Five
trials found no adverse or serious adverse events in the interven
tion group. … Rates of discontinua
tion due to adverse effects were twice as common in the interven
tion group as