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Showing results for "adverse events".
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan151/lipid-disorders-in-children-screening-july-2016January 15, 2015 - between intermediate outcomes ‡ in childhood and adolescence and future incidence of adult MI and stroke events … results, psychosocial effects, overdiagnosis) KQ 7: All harms from lipid-lowering medications (e.g., adverse … events, long-term safety, overtreatment) KQs 1, 5, 8: Diabetes Metabolic syndrome Hypothyroidism … thickness, calcium score, pathological findings) KQ 7: All harms from: Medications (e.g., adverse … events, long-term safety, overtreatment) Lifestyle modifications (e.g., nutritional, psychosocial)
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obstructive-sleep-apnea-in-adults-screeningNovember 15, 2022 - Adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular … men and 6% for women. 1 Severe OSA is associated with increased all-cause mortality. 2 , 3 Other adverse … In general, mild OSA is defined as 5 to 15 events per hour, moderate OSA as 16 to 30 events per hour, … to the increase in prevalence of obesity. 1 , 2 Obstructive sleep apnea is associated with multiple adverse … , mucosal erosions, and jaw or temporomandibular joint pain or discomfort. 15 , 16 In general, the adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary7/thyroid-dysfunction-screeningOctober 28, 2014 - reported “no indication of harms,” 17 and another study stated that none of the patients reported adverse … versus placebo in risk for withdrawal due to adverse events after 12 months (9.6% vs. 14.3%; P = 0.49 … 27 Two other trials (100 and 60 patients) reported 0 28 or 2 30 , 31 cases of withdrawals due to adverse … subclinical hypothyroidism with greater TSH levels, which may be associated with increased risk for adverse … adults and found no difference in withdrawals due to side effects; all other trials reported ad hoc adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/bacterial-vaginosis-in-pregnancy-to-prevent-preterm-delivery-screeningMay 17, 2018 - What are the adverse drug events related to metronidazole or clindamycin when used to treat bacterial … exposure to medication: Teratogenesis (e.g., congenital anomalies) Carcinogenesis Maternal adverse … effects, such as: Tolerability Vaginal candidiasis Serious adverse events (e.g., those resulting
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/bacterial-vaginosis-in-pregnancy-to-prevent-preterm-delivery-screeningApril 07, 2020 - Four trials 35 , 36 , 42 , 47 (n = 1718) reported on adverse events from intravaginal clindamycin. … No serious adverse events were reported. … Only 1 trial reported on serious adverse events and did not observe any in either treatment group. … A higher incidence of adverse events was reported with oral metronidazole in both studies, although the … Asymptomatic bacterial vaginosis and intermediate flora as risk factors for adverse pregnancy outcome
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-for-prediabetes-and-type-2-diabetesAugust 24, 2021 - Most trials reporting mortality or CVD events over a follow-up duration of 6 years or less had few events … Categories and definitions used for adverse events were heterogenous across studies, and few trials ( … 3 trials) reported adverse events beyond 5 years of follow-up. 65 , 66 , 74 Five trials reported rates … Four studies of lifestyle interventions reported on musculoskeletal-related adverse events, 2 found no … Six pharmacologic trials found higher rates of GI adverse events vs controls: metformin (3 trials), acarbose
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/zk8YxjaQxLGUTtt__nBQB_September 09, 2021 - There was also evidence of an in- creased risk of serious adverse events with use of selective seroto … events appears to be relatively low, how- ever, and evidence for specific serious adverse events was … The study of lithium found a higher rate of nonserious adverse events (75.7% with lithium, 69.0% with … , 34.1% with placebo; P value not reported) but no difference in with- drawals due to adverse events … events with all agents examined and a higher risk of serious adverse events with SSRI use (OR, 1.39
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DYFdTVu-UY3h7CWGdA7ZkhJuly 20, 2021 - A register-based study: adverse events in colonoscopies performed in Sweden 2001-2013. … Patient-reported adverse events after colonoscopy in Norway. … Adverse events after outpatient colonoscopy in the Medicare population. … Adverse events after screening and follow-up colonoscopy. … Adverse events of computed tomography colonography: an Italian National Survey.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/G7CCbu64mf-nCynBkHbFLAJuly 01, 2012 - Menopausal hormone therapy to prevent chronic conditions is currently not recommended because of its adverse … update evidence about the effectiveness of hormone therapy in reducing risk for chronic conditions and adverse … The pri- mary outcome was CHD, and the primary adverse event outcome was invasive breast cancer. … disease, fractures, mortal- ity, uterine bleeding, and other adverse effects. … The WHI trials (2, 3) and WISDOM (62) were discontinued prema- turely because of adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-2010January 15, 2010 - Adverse effects included elevated heart rate, elevated blood pressure, and adverse gastrointestinal effects … An examination of the literature on the harms of weight-management programs found no evidence of adverse … Serious adverse events were reported for 2.7% of the patients who were taking sibutramine and <1% of … Adverse events occurred in 3% of the patients who received orlistat compared with 2% of the patients … Incidence and risk factors for perioperative adverse respiratory events in children who are obese.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-diet-and-physical-activity-counseling-for-cvd-prevention-in-adultsJune 15, 2012 - cardiovascular events. … None of the studies reviewed was designed to detect adverse effects of interventions to promote a healthful … The adverse effects of these counseling interventions were also reviewed. … Potential Harms of Counseling Interventions No healthful diet counseling trials reported specific adverse … events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-diet-and-physical-activity-counseling-for-cvd-prevention-in-adults-2012June 15, 2012 - cardiovascular events. … None of the studies reviewed was designed to detect adverse effects of interventions to promote a healthful … The adverse effects of these counseling interventions were also reviewed. … Potential Harms of Counseling Interventions No healthful diet counseling trials reported specific adverse … events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002January 01, 2002 - Enteric-coated or buffered preparations do not clearly reduce adverse gastrointestinal effects of aspirin … Most events occur in older people and those with recognized risk factors for cardiovascular disease, … physicians and patients balance the reduced rate of nonfatal myocardial infarction against potential adverse … Aspirin for the primary prevention of cardiovascular events: recommendations and rationale. … Aspirin for the primary prevention of cardiovascular events: A summary of the evidence for the U.S.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screeningJune 26, 2018 - adverse events (23.8% vs 23.9%; RR, 1.12 [95% CI, 0.88-1.44]; I 2 = 14.1%; 4 RCTs [8663 participants … events, and upper GI tract events Consistent and precise for discontinuations, serious adverse events … events, and upper gastrointestinal events; insufficient for cardiovascular events, osteonecrosis, and … Insufficient for discontinuation; low for no harm for serious adverse events and serious infections … c Pooled estimates include men, women, and combined estimates (1 study did not provide adverse events
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screening-june-2018June 26, 2018 - adverse events (23.8% vs 23.9%; RR, 1.12 [95% CI, 0.88-1.44]; I 2 = 14.1%; 4 RCTs [8663 participants … events, and upper GI tract events Consistent and precise for discontinuations, serious adverse events … events, and upper gastrointestinal events; insufficient for cardiovascular events, osteonecrosis, and … Insufficient for discontinuation; low for no harm for serious adverse events and serious infections … c Pooled estimates include men, women, and combined estimates (1 study did not provide adverse events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/abdominal-aortic-aneurysm-screeningNovember 30, 2017 - aneurysm-related mortality, cardiovascular disease mortality, aneurysm rupture rate, cardiovascular disease events … aneurysm-related mortality, cardiovascular disease mortality, aneurysm rupture rate, cardiovascular disease events … , and quality of life KQ 5: Harms (i.e., serious adverse events from pharmacotherapy or surgery) … response to comments, the USPSTF expanded the scope of the evidence review to include cardiovascular events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/hbCWj_efTz2w9c--Qgbgm8April 07, 2020 - Bacterial vaginosis during pregnancy has been associated with adverse obstetrical outcomes including … Four trials35,36,42,47 (n = 1718) reported on adverse events from intravagi- nal clindamycin. … No serious adverse events were reported. … Only 1 trial reported on serious adverse events and did not observe any in either treatment group. … A higher incidence of adverse events was reported with oral metronidazole in both studies, although the
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Zr66Ep5Abbqcuqy7Ktdetn (pdf file)
www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZR66ep5ABbQCUQy7KTDETnJuly 01, 2014 - However, trials found no difference in the risk for serious adverse events or the number of participants … In addition, most antiviral adverse events were self-limited with discontinuation of therapy. … events (12 trials; RR, 0.8 [CI, 0.6 to 1.1]; I2 � 0%) or any adverse event (7 trials; RR, 0.96 [CI, … Studies did show an increased risk for withdrawal due to adverse events (9 trials; RR, 4.0 [CI, 1.4 to … events (RR, 2.1 [CI, 1.0 to 4.5]; I2 � 0%), with- drawals due to adverse events (RR, 7.6 [CI, 1.1 to -
Interventions to Prevent Perinatal Depression: Evidence Report and Systematic Review for the USPSTF (pdf file)
www.uspreventiveservicestaskforce.org/home/getfilebytoken/-KMSTWRT9xbm7spaqDq_GEFebruary 12, 2019 - They reported only the number of events for 1 of the 11 adverse effects collected; constipa- tion differed … events (but data were not shown). … No harms were associated with omega-3 fatty acids, although reports of adverse events were collected … events were reported in either treatment group Consistency NA, imprecise Low (DHA) Nortriptyline … events such as conversion to mania Insufficient Conducted in the United States Abbreviations: DHA, -
www.uspreventiveservicestaskforce.org/home/getfilebytoken/4y3P9DxovKMEjNmVd2mrPpDecember 01, 2007 - events from the test, the accuracy and potential for adverse events of any subsequent confirmatory diagnostic … to screen (the number of people who would need to be screened for some defined period to prevent 1 adverse … to harm (the number of people who would need to be treated or screened for a defined time to cause 1 adverse … benefits and harms can be challenging—benefits are often quantified in terms of lives extended or illness events … For example, the benefits of prophylactic aspirin therapy among men include fewer coronary heart events
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