-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/VwvmgA5bLZZJhK6YSqRonU
November 01, 2022 - Adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular … events, type 2 diabetes, cognitive impairment, decreased quality of life, and motor vehicle crashes
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
March 15, 2009 - Enteric-coated or buffered preparations do not clearly reduce the adverse gastrointestinal effects of … Clinicians should inform patients about the adverse consequences of gastrointestinal bleeding because … increases the risk for major bleeding events in men and women. … The sex-specific meta-analysis of RCTs described above reported adverse events with aspirin use in the … primary prevention of cardiovascular events in 51,342 women and 44,114 men. 3 Major bleeding events
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-adults-interventions
March 31, 2016 - or pharmacotherapy interventions for weight loss or weight loss maintenance are associated with any adverse … What are the adverse effects of primary care–relevant behavioral and/or pharmacotherapy weight loss and … sleep apnea)
Proportion of individuals taking medication for an obesity-related condition
KQ 3: Adverse … effects
Psychological adverse events related to counseling or medication
KQ 1:
Functioning … trials, including cluster randomized trials
Large cohort or case-control studies reporting serious adverse
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/Wx_w92ukxeDvNShoRQXbhP
September 06, 2016 - A few studies also reported on gastrointestinal adverse
events. … -
nificant increased RR of gastrointestinal adverse events (RR, 1.60
[95% CI, 0.76-3.40]) in 2 studies … .2 All 5 studies also reported on
discontinuation of treatment because of adverse events. … events. … Adverse
events with 4 months of rifampin therapy or 9
months of isoniazid therapy for latent tuberculosis
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/2DGd8AvVMTJwP3ttrPcnLL
February 25, 2020 - NRT found a greater num-
ber of headaches, cough, abnormal dreams, muscle pain, and patch-
related adverse … events with NRT.38 Bupropion carries a boxed warn-
ing for increased risk of suicidality in children … events, including suicidality, seizures, inter-
action with alcohol, cardiovascular events, sleepwalking … on benefits be-
cause its follow-up was less than 6 months.50 No difference in se-
rious or severe adverse … withdrew because of adverse events with bupropion.14 Some stud-
ies reported more headaches, cough,
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-and-nicotine-use-prevention-in-children-and-adolescents-primary-care-interventions
April 28, 2020 - however, most quit attempts fail, and about 80% will go on to smoke into adulthood. 36 Immediate adverse … of NRT found a greater number of headaches, cough, abnormal dreams, muscle pain, and patch-related adverse … events with NRT. 38 Bupropion carries a boxed warning for increased risk of suicidality in children … events, including suicidality, seizures, interaction with alcohol, cardiovascular events, sleepwalking … withdrew because of adverse events with bupropion. 14 Some studies reported more headaches, cough,
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-familial-hypercholesterolemia/lipid-disorders-in-children-screening-july-2016
August 09, 2016 - Bile acid–sequestering agents were commonly associated with adverse gastrointestinal symptoms and poor … No severe, permanent harms of statins were reported, and reported treatment adverse events usually did … events were reported sporadically. … events or with different rates of adverse events compared with a control group at 12 weeks. 34
Relationship … Treatment studies should systematically report adverse effects of treatment.
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/suicide-risk-in-adolescents-adults-and-older-adults-screening
May 20, 2014 - Risk factors for suicide attempt include presence of a mental health disorder; serious adverse childhood … Other important risk factors for suicide attempt include serious adverse childhood events; family history … Potential Harms of Screening
Three studies reported on the potential adverse effects of screening … events were documented in the studies. … Few treatment trials in adults reported adverse events.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/CW23r2jqogvTG2_-kBjRxH
January 01, 2007 - in children/adolescents effective in
delaying the onset and reducing the incidence of CHD-related events … of screening for dyslipidemia in identifying
children/adolescents at increased risk of CHD-related events … incidence of adult dyslipidemia,
and delaying the onset and reducing the incidence of CHD-related events … Drug treatment
Information about adverse events was reported in 15 studies of statins,18, 19, 165, … There are no trials with long-term follow-up for adult
23
lipid outcomes or CHD-related events
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/KdQef_VDT2kmHDX4ddNWmR
August 01, 2022 - isoniazid (RR, 1.50 [95% CI, 1.18-1.89])
and a greater risk of gastrointestinal adverse events (RR, 1.33 … Recent trials also reported on discontinuation due to adverse
events. … There was a statistically nonsignificant increase in discontinu-
ation due to adverse events in a meta-analysis … this was statistically significant in only 1 trial.9,28 Overall, study re-
ports of gastrointestinal adverse … Adverse
events with 4 months of rifampin therapy or 9
months of isoniazid therapy for latent tuberculosis
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/impaired-visual-acuity-in-older-adults-screening-2016
March 01, 2016 - use vs placebo in risk of any adverse events (93% vs 89%; RR, 1.05; 95% CI, 0.97–1.13), serious adverse … events (31% vs 30%; RR, 1.04; 95% CI, 0.72–1.49), or serious ocular adverse events (8.2% vs 7.0%; RR … events, but estimates for those outcomes were imprecise. … events in participants taking zinc vs placebo. … No increase in risk of systemic hypertension or arterial thromboembolic events.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
January 01, 2017 - and hypopnea events). … Overall, 2% to 47% of par-
ticipants in trials reporting any harms had specific adverse events
while … Across studies that reported any
discontinuation because of adverse events, 7% of patients
using MADs … In general, the adverse events related to CPAP treatment
were likely short-lived and could be alleviated … Adverse effects may limit adherence to treatment.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/falls-prevention-in-older-adults-interventions-2018
October 22, 2015 - The figure also depicts the possibility of harms or adverse effects occurring as a result of falls prevention … What are the adverse effects associated with primary care interventions to prevent falls in community-dwelling … Get Up & Go Test, 6-meter timed walk, Functional Reach Test, and Berg Balance Scale)
KQ 2: Minor adverse … events that are reported using nonvalidated, nongeneralizable measures
Study Designs
KQ 1:
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
July 11, 2017 - Among 14 trials of behavioral interventions that reported on adverse events, none reported any serious … adverse events. … Behavioral Counseling Interventions
Of the 88 trials reviewed by the USPSTF, 14 specifically reported on adverse … events. 3 No trials reported any serious adverse events related to the counseling intervention. … events.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/4zmYnqJXLv8g4LzLrrDDrm
December 01, 2014 - effectiveness
of low-dose aspirin in preventing preeclampsia in women at in-
creased risk and in decreasing adverse … events. … Assessment of Risk for Adverse Effects
Low-dose aspirin use in women at increased risk for
preeclampsia … Eighteen trials reported on the outcome of perinatal
mortality (with 4 smaller studies reporting no events … Seven trials reported adverse events; however, most
were determined to be unrelated to treatment.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/mk-eb9VtB_jx885wnjuzk3
January 01, 2024 - Statins were not associated with increased risk of serious adverse events (RR,
0.99 [95% CI, 0.94 to … is the leading cause of mor-
bidity and mortality in the United States.1 A challenge in re-
ducing adverse … Compared with placebo, statin therapy was not associated with
increased risk of withdrawal due to adverse … Few serious adverse events were reported. … events, seri-
ous adverse events, cancer, or elevated liver enzyme levels vs pla-
cebo or no statin
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/impaired-visual-acuity-in-older-adults-screening-2016
March 01, 2016 - antioxidant vitamins and mineral supplements is not associated with increased risk of most serious adverse … events. … with greater likelihood of withdrawal vs sham therapy; there were no differences in serious or other adverse … events, but estimates were imprecise. 1 , 4 , 6 , 7
Current Practice
About half of US adults … event, serious adverse events, serious ocular events, or withdrawal due to adverse events. 1
Treatment
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvcAbDQWejyK38oxF8qgka
November 01, 2012 - Although the USPSTF found that ART
was associated with short-term adverse events and an in-
creased risk … What are the adverse effects (including false-positive results and anxiety) of rapid versus standard … Friis-Møller N, Sabin CA, Weber R, d’Arminio Monforte A, El-Sadr WM,
Reiss P, et al; Data Collection on Adverse … to specific individ-
ual antiretroviral drugs from the 3 major drug classes: the data collection on
adverse … BMI � body mass index; CV � cardiovascular; CVD � cardiovascular disease; DAD � Data Collection on Adverse
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/VNs-WaxpPcsodxCb57gYmn
January 03, 2017 - In addition to mortality, other adverse health
outcomes associated with untreated OSA include cardiovascular … mortality independently, beyond the contributions
of age, BMI, and other confounding factors.1 Other adverse … Overall, 2% to 47% of trial participants reported any
adverse effects from treatment with CPAP, including … been
found to be associated with an increased risk of all-cause and car-
diovascular mortality.1 Other adverse … performance; and decreased quality of life.1 However, it is unclear
what role OSA plays in causing these adverse
-
www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-adolescents-and-adults-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
November 20, 2012 - Although the USPSTF found that ART was associated with short-term adverse events and an increased risk … With ART
The 2005 USPSTF review included results from the large, ongoing DAD (Data Collection on Adverse … Friis-Møller N, Sabin CA, Weber R, d'Arminio Monforte A, El-Sadr WM, Reiss P, et al; Data Collection on Adverse … What are the adverse effects (including false-positive results and anxiety) of rapid versus standard … BMI = body mass index; CV = cardiovascular; CVD = cardiovascular disease; DAD = Data Collection on Adverse