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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6L2obA88s86MoZDbWtMPTU
December 01, 2011 - Vitamin D with or
without calcium
supplementation
vs. placebo
Adverse
events
All 63 RCTs included … events and
were not adequately powered to
detect adverse events.
1 RCT in postmenopausal women (n � … Adverse Events Associated With Vitamin D With or
Without Calcium
The Women’s Health Initiative trial … events and were not adequately powered to
detect adverse events. … However,
these adverse events may or may not be associated with the
vitamin D or calcium supplements.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/oZSntFpszryu7mAnjdhkrw
September 05, 2023 - , adverse events. … Outcomes reported include (1) suicide-related harms, (2) with-
drawal due to adverse events, (3) and … serious adverse events. … Regarding withdrawal due to adverse events, the pooled
RR for CBT trials was 0.39 (95% CI, 0.08 to 1.87 … The evidence suggests that suicide-
related harms, serious adverse events, and withdrawal due to ad-
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/latent-tuberculosis-infection-screening-september-2016
September 06, 2016 - A few studies also reported on gastrointestinal adverse events. … nonsignificant increased RR of gastrointestinal adverse events (RR, 1.60 [95% CI, 0.76 to 3.40]) in … 2 studies. 2 All 5 studies also reported on discontinuation of treatment because of adverse events. … events. … Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/poDYcagnw7SqKNNbrFt_CV
June 11, 2019 - Limited data suggest that PrEP
use is not associated with significant adverse events in adolescents
but … There
was no clear difference in risk of kidney adverse events when trials
were stratified according … of serious renal events or with-
drawals due to renal events.31,32 Six trials41,42,55-58 evaluated
whether … renal adverse events while using PrEP were persistent. … The risk of gastrointes-
tinal adverse events increased with both tenofovir disoproxil fuma-
rate monotherapy
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-in-adults-screening-2009
December 15, 2009 - Also, information on the possible adverse effects and harms of depression care management programs is … events from antidepressant treatment in all adults. … effects of treatment of patients who are incorrectly identified as being depressed, and potential adverse … Harms of treatment include serious adverse effects of antidepressants, such as suicide-related events … For older adults, harms of treatment also include serious medical events, such as UGI bleeding.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening-january-2017
January 24, 2017 - Overall, 2% to 47% of participants in trials reporting any harms had specific adverse events while using … Across studies that reported any discontinuation because of adverse events, 7% of patients using MADs … In general, the adverse events related to CPAP treatment were likely short-lived and could be alleviated … Adverse effects may limit adherence to treatment. … and Associated Events.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening
June 24, 2025 - in women assigned to the intervention group compared with the control group. 1 , 35 In 1 study, IPV events … were lower in the intervention group (7.50 events per person-year) compared with the control group ( … 9.55 events per person-year) at 3 years, but the difference was not statistically significant (incident … rate ratio of average IPV events per person-year, 0.86 [95% CI, 0.73-1.01]). 47 The other home-visit … events; however, it was unclear whether events were prespecified or how they were monitored. 1 , 35
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary29/obstructive-sleep-apnea-in-adults-screening
November 15, 2022 - per hour), moderate (16-30 events per hour), and severe (>30 events per hour). … Overall, too few events occurred to draw conclusions. … In general, the adverse events related to positive airway pressure treatment were likely short-lived … Common adverse events included oral or nasal dryness, eye or skin irritation, and rash. … : overall, too few events were observed to draw conclusions
Mortality and cardiovascular events:
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/vitamin-d-calcium-combined-supplementation-primary-prevention-falls-fractures-communitydwelling-adults
December 17, 2024 - There were no significant differences in adverse events or serious adverse events in participants randomized … minority of trials reported these outcomes, and ascertainment methods and details provided related to adverse … or serious adverse events varied among trials. 10
Eleven trials reported on the incidence of participants … Two trials compared calcium alone with placebo, but the sample sizes were small and events were rare,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/hbSopN6uA9u-4EQuKtRGDP
October 01, 2011 - events
Context
Experts recommend that primary care clinicians offer
obese adults interventions that … events (Table 2) (22, 83,
102). … No studies re-
ported serious adverse effects. … Summary of Medication Harms
Adverse Events Trials in
Meta-analysis,
Additional
Trials, n, n
Meta-analysis … Meridia (sibutramine): market with-
drawal due to risk for serious cardiovascular events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary38/obesity-in-adults-screening-and-management-2012
October 15, 2011 - events into standardized evidence tables 9 . … events ( Table 2) 22 , 83 , 102 . … No studies reported serious adverse effects. … Meridia (sibutramine): market withdrawal due to risk for serious cardiovascular events. … The figure also depicts the possibility of harms or adverse events occurring as a result of screening
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/36geybKjEXsHDoPkRR5KVZ
June 01, 2008 - review for this current recommendation focused on evidence that
early treatment prevented long-term adverse … USPSTF reviewed the evidence on early treat-
ment of type 2 diabetes mellitus in preventing long-term
adverse … No studies reported adverse effects of receiving a
diagnosis of IFG or IGT, and no studies examined … Angiotensin-converting en-
zyme inhibitors and statins have reasonably low levels of
serious adverse … The relationship between
glucose and incident cardiovascular events.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - in effect by age group, although rare events limited all analyses. … Rationale for a trial of low-dose aspirin for the primary prevention of major adverse cardiovascular … events and vascular dementia in the elderly: Aspirin in Reducing Events in the Elderly (ASPREE). … Aspirin effect on the incidence of major adverse cardiovascular events in patients with diabetes mellitus … prevented events).
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary28/cognitive-impairment-in-older-adults-screening-2014
October 22, 2013 - However, total serious adverse events did not seem to differ for these medications across trials with … The definitions of serious adverse events were not commonly described in the included studies. … Observational studies suggest that bradycardia and adverse events related to it (for example, fall or … Only 1 of the included trials mentioned harms, and it found no adverse events in either group. … events are CNS, heart rate/rhythm, and gastrointestinal disorders and that bradycardia and adverse events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mx2Ko29RH46mTYb36f-UBe
June 20, 2023 - events, even if they have proven
benefits. … events. … Evidence demonstrated an increase in
nonserious harms (defined as any adverse events and withdrawals … due to adverse events). … Serious adverse events were rare and data
were insufficient to determine whether pharmacotherapy
increased
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
November 24, 2020 - . 11 , 16 Twelve of these trials reported cardiovascular events, and among the trials with a composite … reviewed by the USPSTF, only 20 specifically reported on harms, and 8 of these specifically reported no adverse … events. 11 , 16
Few trials reported details about the adverse events, but most were minor. … Serious adverse events were rare. 11 , 16 There was no consistent evidence that behavioral counseling … Large replication studies of interventions showing reductions in CVD events are urgently needed.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/high-cholesterol-other-lipid-abnormalities-screening-1996
January 01, 1996 - due to effects of estrogen, 5 but women account for 49% of all CHD deaths in the U.S. 2 Clinical events … 3%. 20 High cholesterol (≥240 mg/dL) is also a risk factor in middle-aged women, but most coronary events … nonlipid risk factors, persons with cholesterol below 240 mg/dL account for the majority of all CHD events … New insights into prevention of plaque disruption and clinical events in coronary disease. … Review of dietary intervention studies: effect on coronary events and on total mortality.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/72-qtLK_m7urbSFT2yQZ2A
June 01, 2023 - previously and using clinical
judgment while considering risk factors, comorbid conditions, and life events … depression, prior episodes of depression or other
mental health conditions, a history of trauma or adverse … life events, or a history of disease or illness
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/breast-cancer-medications-for-risk-reduction
September 03, 2019 - Vasomotor symptoms (hot flashes) are a common adverse effect of both medications. … potential benefit of risk reduction of breast cancer must be balanced against the potential harms of adverse … benefit from risk-reducing medications for breast cancer, as well as evidence on the effectiveness, adverse … offering risk-reducing medications to women at increased risk for breast cancer and at low risk for adverse … Safety and adverse effects associated with raloxifene: multiple outcomes of raloxifene evaluation.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/PdBbRgWKPMbHfeQeHkM242
February 01, 2010 - Adverse effects included elevated
heart rate, elevated blood pressure,
and adverse gastrointestinal effects … Serious adverse
events were reported for 2.7% of the
patients who were taking sibutra-
mine and �1% of … Adverse
events occurred in 3% of the patients
who received orlistat compared with
2% of the patients … They also commonly experi-
enced mild-to-moderate adverse
gastrointestinal effects, with 20% to
30% reporting … Incidence and risk factors for
perioperative adverse respiratory events in
children who are obese.