-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary27/screening-depression-suicide-risk-children-adolescents
October 11, 2022 - , and adverse events. … Differences in suicide-related outcomes and adverse events for pharmacotherapy when compared with placebo … ideation) and other adverse events. … One study 53-55 reported on adverse events, serious adverse events, and other harms during the 12- to … events and serious adverse events, precise effects unclear owing to inconsistent study reporting
Collaborative
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/kHT3WGUaG2wTz2pF_ke7bn
persons
to better understand
and report on
accuracy in this
group
major osteoporotic fracture
events … osteoporotic fractures§, clinical
vertebral fractures, any clinical
fragility fractures
KQ5:
Total adverse … events
Total serious adverse events
Specific serious adverse events:
major cardiovascular events … of the jaw, atypical femur
fractures, incident
gastrointestinal cancer, serious
gastrointestinal events … , rebound
fractures after discontinuing
denosumab treatment
Discontinuations because of
adverse events
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/impaired-visual-acuity-screening-older-adults
May 24, 2022 - or other serious adverse events, although no statistically significant differences were reported. 24 … vitamin E or placebo, and no differences in risk of withdrawal due to adverse events or specific adverse … but did not indicate increased risk of serious adverse events or withdrawal due to adverse events. … events, cardiovascular events, or serious ocular adverse events
Three trials found that serious ocular … events or withdrawal due to adverse events
Consistent
Precise for the AREDS formulation but imprecise
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/eSLqaKpvzhYRbQVeumNgSQ
January 19, 2021 - None of the drugs were
associated with serious adverse events. … events, including major cardiovascular adverse events
or serious neuropsychiatric events, as compared … events
NRT was associated with a higher rate of any
cardiovascular adverse events, largely driven by … events, particularly cardiovascular- or
neuropsychiatric-specific adverse events
Adverse events typically … events
NA Very few reviews assessed adverse events related to
behavioral interventions
Moderate evidence
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
November 18, 2021 - KQ 5 (Treatment harms):
Total adverse events.
Total serious adverse events. … Specific serious adverse events: Major cardiovascular events (i.e., myocardial infarction, stroke, cardiovascular … osteonecrosis of the jaw, atypical femur fractures, incident gastrointestinal cancer, serious gastrointestinal events … Discontinuations because of adverse events.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/uM5P-6XpsqVfEC2axGnZaD
November 16, 2020 - • A statistically nonsignificant increase in severe adverse events
was found with bupropion SR, but … may be associated with
an increased risk of general severe adverse events … Cardiac adverse events and other serious adverse events did not dif-
fer by type of NRT.63
The USPSTF … events (RR, 1.30 [95% CI, 1.00-
1.69]; 33 trials; n = 9631),83 cardiovascular adverse events (RR,
1.03 … events or cardiovascular severe adverse events was
found.13 Additionally, no statistically significant
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-anxiety-children-adolescents
October 11, 2022 - These adverse childhood experiences may be blatant or subtle (eg, microaggressions) but are potentially … Pharmacologic interventions may result in adverse events, while psychological interventions are likely … These trials also showed lower rates of withdrawal due to adverse events and serious adverse events in … , psychiatric adverse events, and withdrawals due to adverse events; however, these events were rare … Making the "C-ACE" for a culturally-informed adverse childhood experiences framework to understand the
-
www.uspreventiveservicestaskforce.org/uspstf/document/behavioral-counseling-and-pharmacotherapy-interventions-for-/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions-september-2015
September 21, 2015 - None of the drugs were associated with major cardiovascular adverse events. … Adverse Events
One review reported minor adverse events related to ear acupuncture, ear acupressure … Although more serious adverse events occurred in the nicotine e-cigarette group (27 events [19.7%]) than … Adverse Events
None of the reviews on behavioral interventions among pregnant women reported adverse … Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis-june-2019
July 26, 2017 - with antiretroviral drug–resistant HIV, gastrointestinal harms, headaches, and discontinuation due to adverse … events (key question 5). … * Harms also include renal dysfunction, adverse effects on bone, pregnancy-related outcomes, infection … with antiretroviral drug–resistant HIV, gastrointestinal harms, headaches, and discontinuation due to adverse … events.
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-c-screening
March 02, 2020 - event data, the pooled rate of any adverse event was 73.3%. 1 Rates of serious adverse events (1.9% … ) and withdrawal due to adverse events (0.4%) were low compared with rates reported for interferon-containing … regimens. 1 Pooled rates of specific adverse events ranged from 2.4% for anemia to 18.4% for headache … Five trials reported no withdrawals due to adverse events; 1 trial reported a serious adverse event ( … fatigue (7 trials), and 3% to 28% for gastrointestinal adverse events (nausea, vomiting, or diarrhea
-
www.uspreventiveservicestaskforce.org/uspstf/document/comparative-effectiveness-of-antiviral-treatment-for-hepatitis-c-virus-infection-in-adults-a-systematic-review/hepatitis-c-screening-2013
November 15, 2012 - Harms included withdrawals due to adverse events, serious adverse events, neutropenia, anemia, psychological … adverse events, influenza-like symptoms, and rash. … There were no differences in risk for withdrawal due to adverse events, serious adverse events, or other … adverse events. … events, withdrawal due to adverse events, neutropenia, depression, fatigue, headache, chills/rigors,
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/obesity-in-children-and-adolescents-screening
June 18, 2024 - event or serious adverse events or decreases in self-esteem, body satisfaction, or disordered eating … events, serious adverse events, self-esteem, body satisfaction, or disordered eating
Outcomes reported … events: insufficient
Any adverse events: low for increased harm
Largest trial providing most of … events: insufficient
Any adverse events: low for increased harm
Multinational study, including … events: insufficient
Any adverse events: low for increased harm
Larger study conducted in the
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/B73a4kJhxeaYyXK6gozbbY
May 24, 2022 - vitamin E or pla-
cebo, and no differences in risk of withdrawal due to adverse events
or specific adverse … but did not
indicate increased risk of serious adverse events or withdrawal due
to adverse events. … events, cardiovascular
events, or serious ocular adverse events
Three trials found that serious ocular … adverse events were
infrequent and occurred in similar proportions of patients
randomized to either … events or withdrawal due to adverse events
Consistent
Precise for the
AREDS formulation
but imprecise
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qpv8h6ZMbYLYzakVrNQoj2
October 11, 2022 - , and adverse events. … Differences in suicide-related outcomes and adverse events for pharmacotherapy when
compared with placebo … The TADS trial reported a higher but not statistically sig-
nificant difference in adverse events for … One
study53-55 reported on adverse events, serious adverse events, and
other harms during the 12- to … events and serious adverse events, precise effects
unclear owing to inconsistent study reporting
Collaborative
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/high-blood-pressure-adults-children-adolescents-screening-2003
April 01, 2003 - Treatment of elevated blood pressure in adults can reduce cardiovascular events. … The adverse effects of screening or treatment for hypertension. … Adverse Effects of Screening for Hypertension
We identified 10 cohort studies examining the adverse … Adverse Effects of Treatment of Hypertension
Serious or life-threatening adverse drug reactions have … Prevention of an adverse impact in those at high risk. Am J Med 1982;73(2):165-70. 63.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan98/statin-use-in-adults-preventive-medication-november-2016
May 02, 2014 - The population includes adults ages 21 to 39 years without prior CVD events. … The population includes adults age 40 years and older without prior CVD events. … as identified in the literature)
KQs 1, 4, 5: Outcomes not listed as included
KQ 2: Adverse … outcomes not associated with screening
KQ 3: Outcomes not listed as included
KQ 6: Other adverse … outcomes (e.g., lipid levels or measures of atherosclerosis, such as intima media thickness)
KQ 2: Adverse
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2013
September 15, 2013 - events. … events. … events, uterine abnormalities, cataracts, and other adverse effects. … cataracts, and other adverse effects. … The USPSTF also considered meta-analysis summary calculations of the number of adverse health events
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/BXkaHRFGjwUCoyANeMSuTz
January 01, 2010 - The relative risk for adverse events associated with
hypertension is continuous and graded (2,8); systolic … Adverse Effects of Screening
for Hypertension
We identified 10 cohort studies examining the
adverse … These studies did not find any evidence for
adverse psychological effects. … Adverse Effects of Treatment of
Hypertension
Serious or life-threatening adverse drug reactions
have … Less serious adverse effects have
been noted to occur with most drugs (68).
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/latent-tuberculosis-infection-screening
May 02, 2023 - A total of 345 patients (1.8%) receiving isoniazid discontinued treatment because of adverse events, … The RR of discontinuation due to adverse events among patients treated with isoniazid vs placebo was … Rates of discontinuation because of adverse events were reported in all 4 included RCTs, but 1 trial … Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: … events and other gastrointestinal adverse events
Fair
Harm ascertainment techniques not well described
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/early-food-allergen-introduction-infants-counseling
May 09, 2024 - allergenic foods (KQ1 only)
KQ2: Psychological harms (e.g., anxiety)
KQ4:
Withdrawal due to adverse … events, as reported in the studies
Serious adverse events attributable to the intervention, including