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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kHT3WGUaG2wTz2pF_ke7bn
January 14, 2025 - persons
to better understand
and report on
accuracy in this
group
major osteoporotic fracture
events … osteoporotic fractures§, clinical
vertebral fractures, any clinical
fragility fractures
KQ5:
Total adverse … events
Total serious adverse events
Specific serious adverse events:
major cardiovascular events … of the jaw, atypical femur
fractures, incident
gastrointestinal cancer, serious
gastrointestinal events … , rebound
fractures after discontinuing
denosumab treatment
Discontinuations because of
adverse events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/q_zxLD9JZFGoSPCrEHNk2g
June 11, 2019 - events with abacavir use based on 4 cohort stud-
ies, including the Data Collection on Adverse Events … Hepatic and Renal Adverse Events
Analysis of data from the D:A:D study (n = 45 544) found long-
term … Some new evidence also indicates that
long-term hepatic, renal, and bone (fracture) adverse events are … Mocroft A, Lundgren JD, Ross M, et al; Data
Collection on Adverse Events of Anti-HIV Drugs
(D:A:D) Study … Comparative safety and neuropsychiatric adverse
events associated with efavirenz use in first-line
antiretroviral
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/bQNXFv9Q5uaAQvWH6B7VWV
June 11, 2019 - PrEP was associated with an increased risk of
renal adverse events (12 trials; RR, 1.43 [95% CI, 1.18 … -1.75]; I2 = 0%; ARD, 0.56% [95% CI,
0.09%-1.04%]) and gastrointestinal adverse events (12 trials; RR … , 1.63 [95% CI, 1.26-2.11];
I2 = 43%; ARD, 1.95% [95% CI, 0.48%-3.43%]); most adverse events were mild … PrEP was associated with increased risk vs placebo of renal
adverse events (12 trials [n = 18 170]; … events
Good Most trials did not report
withdrawals resulting from
adverse events Composite
outcome,
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/tobacco-smoking-cessation-in-adults-including-pregnant-women-interventions
June 02, 2020 - Cardiac adverse events and serious adverse events did not differ by type of NRT. 31
The USPSTF considered … events (RR, 1.30 [95% CI, 1.00 to 1.69]; k=33; n=9,631), 32 cardiovascular adverse events (RR, 1.03 … events or cardiovascular severe adverse events was found. 12 No statistically significant increase in … in study withdrawals due to adverse events was seen and no increased risk of cardiovascular events ( … be associated with an increased risk of general severe adverse events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Aqm6uW6_HrTRVJ-EVCVaRV
March 01, 2013 - Serious adverse events were rarely
reported, and there were no deaths in
any of the studies. … A third study reported 8 seri
ous adverse events among 304 patients,
although none were considered … rates or in withdrawals due to adverse
events. … to a dosing error, serious
adverse events were generally not deemed
treatment related. … events,
including headache (the most commonly
reported adverse event), cardiac events,
gastrointestinal
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/blood-pressure-in-children-and-adolescents-hypertension-screening-october-2013
October 15, 2013 - Short-term pharmacologic treatments generally seemed to be well-tolerated, with no serious adverse events … Commonly reported adverse events associated with hypertension medications included headache, cardiac … events and serious adverse events between active intervention and placebo groups. … effects, and had limited power to identify rare adverse events 1 . … Evidence on adverse events associated with interventions that combine medication and lifestyle modifications
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan88/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
February 18, 2014 - individuals with mental health conditions, lead to improved health outcomes, tobacco abstinence, or adverse … events.
… What adverse events are associated with tobacco cessation interventions? … events
Serious treatment-related harms at any time point after the intervention began … events associated with medications
Paradoxical increase in tobacco use
Demoralization
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan88/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions-september-2015
February 18, 2014 - individuals with mental health conditions, lead to improved health outcomes, tobacco abstinence, or adverse … events.
… What adverse events are associated with tobacco cessation interventions? … events
Serious treatment-related harms at any time point after the intervention began … events associated with medications
Paradoxical increase in tobacco use
Demoralization
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary15/blood-pressure-in-adults-hypertension-screening
October 15, 2007 - events are uncommon. … Serious adverse effects were uncommon, and 2 of the 3 reported events were probably not related to the … due to adverse events was 11%. … Other adverse events were hyperkalemia in 2 eplerenone recipients and 1 amlodipine recipient, and hypokalemia … events are uncommon.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/KSYrhQuAswGjTww_4sDFGZ
December 01, 2007 - events are
uncommon. … Serious adverse effects were uncommon, and 2 of the 3
reported events were probably not related to the … due to adverse events
was 11%. … Other adverse events were hyperkalemia
in 2 eplerenone recipients and 1 amlodipine recipient, and
hypokalemia … events are uncommon.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary15/blood-pressure-in-adults-hypertension-screening-2007
October 15, 2007 - events are uncommon. … Serious adverse effects were uncommon, and 2 of the 3 reported events were probably not related to the … due to adverse events was 11%. … Other adverse events were hyperkalemia in 2 eplerenone recipients and 1 amlodipine recipient, and hypokalemia … events are uncommon.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/U4Vu9hcmHtD7snox6qbPja
June 21, 2022 - The 3 trials that reported the total number of
adverse events,51,77 serious adverse events,77 or withdrawals … events,36,39,61,63,65,76,87,90 any serious adverse events,28,40,50,83,86,90
or withdrawal due to adverse … events,40,42,50,67,71,75,83,86,90 only 1 found
an increase in withdrawals due to adverse events in a … ,61 any serious adverse events,28 and withdrawals due
to adverse events30,53 identified very few events … effects,
any serious adverse effects, and
withdrawal due to adverse effects
sparely reported; kidney
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan54/colorectal-cancer-screening
April 17, 2014 - b) Do adverse effects vary by important subpopulations (e.g., by age)? … events requiring unexpected or unwanted medical attention and/or resulting in death (e.g., requiring … including but not limited to perforation, major bleeding, severe abdominal symptoms, and cardiovascular events … ; extra-colonic findings and subsequent diagnostic workup and adverse events from diagnostic testing … events defined as those not necessarily needing or resulting in medical attention (e.g., patient dissatisfaction
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan54/colorectal-cancer-screening-june-2016
April 17, 2014 - b) Do adverse effects vary by important subpopulations (e.g., by age)? … events requiring unexpected or unwanted medical attention and/or resulting in death (e.g., requiring … including but not limited to perforation, major bleeding, severe abdominal symptoms, and cardiovascular events … ; extra-colonic findings and subsequent diagnostic workup and adverse events from diagnostic testing … events defined as those not necessarily needing or resulting in medical attention (e.g., patient dissatisfaction
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-anxiety-children-adolescents
October 11, 2022 - These adverse childhood experiences may be blatant or subtle (eg, microaggressions) but are potentially … Pharmacologic interventions may result in adverse events, while psychological interventions are likely … These trials also showed lower rates of withdrawal due to adverse events and serious adverse events in … , psychiatric adverse events, and withdrawals due to adverse events; however, these events were rare … Making the "C-ACE" for a culturally-informed adverse childhood experiences framework to understand the
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/osteoporosis-screening-prevent-fractures
August 12, 2021 - risk prediction
Radiation exposure
Anxiety from labeling
KQ 5 (Treatment harms):
Total adverse … events
Total serious adverse events
Specific serious adverse events (osteonecrosis of the jaw, atypical … femur fractures, incident gastrointestinal cancer, serious gastrointestinal events, rebound fractures … after discontinuing treatment)
Discontinuations because of adverse events
KQs 1, 4:
Radiographic
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-kidney-disease-screening
July 13, 2023 - change in albuminuria)
KQs 1, 4, 6: Progression to stage 4 or stage 4/5 CKD
KQs 2, 5, 8:
Any adverse … events
Serious adverse events
Specific adverse events
Renal adverse events
KQs 3, 3a:
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZYao53-sqRb6oZzKzDmjjt
December 01, 2003 - Adverse event rate: 18/60
Placebo:
Dropout: 10/59
Due to adverse event: NR
Adverse event rate: 7/59 … event: 20/265
55.6% 31.3% < 0.001 Due to GI symptoms: 13/265
24.3% Serious adverse events: 13/265
> … : 6/266
Serious adverse events: 17/266
–4.7 kg –2.9 kg < 0.001 Orlistat: Fair
–1.8 kg Dropout: 35% … events were
similar in drug and placebo arms.84,86–88
Adverse events were reported in 7.4% to 18%
more … events and
appreciable cost.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
January 19, 2021 - Cardiac adverse events and other serious adverse events did not differ by type of NRT. 63
The USPSTF … events (RR, 1.30 [95% CI, 1.00-1.69]; 33 trials; n = 9631), 83 cardiovascular adverse events (RR, 1.03 … events or cardiovascular severe adverse events was found. 13 Additionally, no statistically significant … Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. … be associated with an increased risk of general severe adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis-june-2019
July 26, 2017 - with antiretroviral drug–resistant HIV, gastrointestinal harms, headaches, and discontinuation due to adverse … events (key question 5). … * Harms also include renal dysfunction, adverse effects on bone, pregnancy-related outcomes, infection … with antiretroviral drug–resistant HIV, gastrointestinal harms, headaches, and discontinuation due to adverse … events.