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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/asymptomatic-bacteriuria-in-adults-screening
September 24, 2019 - events associated with treatment of asymptomatic bacteriuria. … events (not specified) among those treated with trimethoprim-sulfamethoxazole compared with placebo, … events
Most studies reported no adverse events or only on those few patients who withdrew from … the trials based on adverse events
One study of treatment of women with diabetes found higher rates … of adverse events among women in the treatment group
Inconsistent; imprecise
Limited data reporting
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/3qpQqeeozW8nV3a4_BWntp
June 20, 2019 - Along with other adverse events,
HAART is associated with an increased risk for cardiovascular
complications … Long-term data on
adverse events associated with HAART are not yet available. … Many antiretroviral-associated adverse
events, however, are short-term or self-limited, and effec-
tive … Certain drugs and combinations are
not recommended because of associated adverse events. … In a large (n � 1160), good-quality Swiss co-
hort study of adverse events in clinical practice, 47%
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lipid-disorders-children-adolescents-screening
August 19, 2021 - . † CVD events are defined as myocardial infarction or ischemic stroke. … and adolescents delay or reduce the incidence of health outcomes (e.g., cardiovascular disease [CVD] events … * CVD events are defined as myocardial infarction or ischemic stroke. … positives/negatives
KQ 5 (Treatment harms): All harms from:
Lipid-lowering medications (e.g., adverse … events, long-term safety, overtreatment)
Lifestyle modifications (e.g., nutritional, psychosocial)
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/lipid-disorders-in-children-screening
August 19, 2021 - . † CVD events are defined as myocardial infarction or ischemic stroke. … and adolescents delay or reduce the incidence of health outcomes (e.g., cardiovascular disease [CVD] events … * CVD events are defined as myocardial infarction or ischemic stroke. … positives/negatives
KQ 5 (Treatment harms): All harms from:
Lipid-lowering medications (e.g., adverse … events, long-term safety, overtreatment)
Lifestyle modifications (e.g., nutritional, psychosocial)
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/-qaKjceN9BTy-oh7EFwXtk
January 14, 2025 - Compared with placebo, no statistically significant associations were observed
for adverse events. … events. … events, se-
rious adverse events, or gastrointestinal adverse events are shown
in Figure 4. … KQ5: Harms of treatment
Bisphosphonates
Discontinua-
tions due to
adverse events
27 RCTs160-168,170,172,173,175,180 … events and serious adverse events and
moderate for no effect on upper gastrointestinal adverse events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/R_cAa3AjFGQ2np_aQnzQGA
February 11, 2025 - Compared with placebo, no statistically significant associations were observed
for adverse events. … events. … events, se-
rious adverse events, or gastrointestinal adverse events are shown
in Figure 4. … KQ5: Harms of treatment
Bisphosphonates
Discontinua-
tions due to
adverse events
27 RCTs160-168,170,172,173,175,180 … events and serious adverse events and
moderate for no effect on upper gastrointestinal adverse events
-
www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-viii-standardization-outcome-tables
July 01, 2017 - Adverse events/states.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/R33bUm6oyjhWnbw96pJHwE
April 01, 2009 - events. … we calculated pooled absolute RDs for suicide-related
adverse events (SREs) using data for a subset … Suicidal adverse events in pediatric
randomized, controlled clinical trials of antidepressant drugs
are … Treatment-emergent adverse events from
selective serotonin reuptake inhibitors by age group: Children … To
incorporate more conservative estimates of adverse events into the
review, we included results frommeta-analyses
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis-june-2019
June 11, 2019 - Limited data suggest that PrEP use is not associated with significant adverse events in adolescents but … There was no clear difference in risk of kidney adverse events when trials were stratified according … serious renal events or withdrawals due to renal events. 31 , 32 Six trials 41 , 42 , 55-58 evaluated … whether renal adverse events while using PrEP were persistent. … The risk of gastrointestinal adverse events increased with both tenofovir disoproxil fumarate monotherapy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/boPWHmzrtxnkkPQAoCNENS
September 18, 2018 - events (treatment-
related harms and discontinuation of medication because of adverse
effects at any … Rates of adverse events were infrequently reported in the be-
havior-based weight loss and weight loss … Weight loss
medications were associated with more adverse events than pla-
cebo, which was associated … with higher dropout rates for adverse
events in the medication groups than in the placebo groups. … Although rates
of serious adverse events were low and generally similar between
groups, participants
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan141/obesity-in-children-and-adolescents-screening
February 12, 2015 - The analytic framework also depicts the possible adverse events occurring after screening (KQ2) or treatment … Does screening for obesity in children and adolescents have adverse effects? … Do weight management interventions * for children and adolescents have adverse effects? … syndrome, and polycystic ovarian syndrome
Liver dysfunction/nonalcoholic fatty liver disease
Adverse … after baseline
KQ 5 (serious harms of pharmacotherapy): No minimum followup; serious harms are events
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan141/obesity-in-children-and-adolescents-screening-june-2017
February 12, 2015 - The analytic framework also depicts the possible adverse events occurring after screening (KQ2) or treatment … Does screening for obesity in children and adolescents have adverse effects? … Do weight management interventions * for children and adolescents have adverse effects? … syndrome, and polycystic ovarian syndrome
Liver dysfunction/nonalcoholic fatty liver disease
Adverse … after baseline
KQ 5 (serious harms of pharmacotherapy): No minimum followup; serious harms are events
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/hWzpnYXDpQzUr8U_5xY6qS
January 01, 2003 - As a result, individuals with higher absolute risk for
experiencing future adverse cardiovascular events … cardiovascular
events. … Potential adverse effects of drugs—some sufficiently
bothersome to interfere with adherence to the medica … -
tion regimen—are common, but serious adverse drug
reactions are rare. … Physicians should take adverse ef-
fects into consideration when deciding whether to treat
and which
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
July 26, 2022 - Twenty-three of the 113 included trials specifically mentioned the occurrence of adverse events or lack … of adverse events (n = 12,452). … Thirteen trials reported adverse events or serious adverse events of any kind, 29-31 , 33 , 41 , 48 , … reported or that no adverse events related to the trial were evident but no additional details were … provided. 33 , 41 , 51 , 62 , 114 , 132 , 136 The other 6 trials found that rates of adverse events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
January 14, 2025 - Compared with placebo, no statistically significant associations were observed for adverse events. … events, serious adverse events, or gastrointestinal adverse events are shown in Figure 4 . … events and serious adverse events and moderate for no effect on upper gastrointestinal adverse events … for bisphosphonates and low for increased upper gastrointestinal adverse events for denosumab. … KQ5: Harms of treatment
Bisphosphonates
Discontinuations due to adverse events
27
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/menopausal-hormone-therapy-preventive-medication-2012
October 15, 2012 - the risk for fractures in postmenopausal women, there is an accompanying increased risk for serious adverse … Cardiovascular events. … Thromboembolic events. … The USPSTF found insufficient evidence to determine whether hormone therapy has an adverse effect on … The magnitude of adverse consequences associated with postmenopausal hormone therapy is moderate; the
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/human-immunodeficiency-virus-hiv-infection-screeni
July 05, 2005 - Along with other adverse events, HAART is associated with an increased risk for cardiovascular complications … Long-term data on adverse events associated with HAART are not yet available. … Many antiretroviral-associated adverse events, however, are short-term or self-limited, and effective … and combinations are not recommended because of associated adverse events. … In a large ( n = 1,160), good-quality Swiss cohort study of adverse events in clinical practice, 47%
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2005
July 05, 2005 - Along with other adverse events, HAART is associated with an increased risk for cardiovascular complications … Long-term data on adverse events associated with HAART are not yet available. … Many antiretroviral-associated adverse events, however, are short-term or self-limited, and effective … and combinations are not recommended because of associated adverse events. … In a large ( n = 1,160), good-quality Swiss cohort study of adverse events in clinical practice, 47%
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
January 18, 2024 - What are the adverse effects of: 3a) risk assessment, 3b) genetic counseling, 3c) genetic testing, and … What are the potential adverse effects of interventions to reduce risk for BRCA1/2 -related cancer in … 3b: Inaccurate risk assessment; inappropriate testing; false-positive and false-negative results; adverse … , and social implications KQ 3c: Inappropriate testing; false-positive and false-negative results; adverse … overdiagnosis, overtreatment, and nonadherence); risk-reducing medications (thromboembolic and cardiovascular events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-depression-suicide-risk-adults
June 20, 2023 - There was also evidence of an increased risk of serious adverse events with use of selective serotonin … events appears to be relatively low, however, and evidence for specific serious adverse events was very … The study of lithium found a higher rate of nonserious adverse events (75.7% with lithium, 69.0% with … , 34.1% with placebo; P value not reported) but no difference in withdrawals due to adverse events … events with all agents examined and a higher risk of serious adverse events with SSRI use (OR, 1.39