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www.uspreventiveservicestaskforce.org/uspstf/recommendation/high-cholesterol-other-lipid-abnormalities-screening-1996
January 01, 1996 - due to effects of estrogen, 5 but women account for 49% of all CHD deaths in the U.S. 2 Clinical events … 3%. 20 High cholesterol (≥240 mg/dL) is also a risk factor in middle-aged women, but most coronary events … nonlipid risk factors, persons with cholesterol below 240 mg/dL account for the majority of all CHD events … New insights into prevention of plaque disruption and clinical events in coronary disease. … Review of dietary intervention studies: effect on coronary events and on total mortality.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/oZSntFpszryu7mAnjdhkrw
September 05, 2023 - , adverse events. … Outcomes reported include (1) suicide-related harms, (2) with-
drawal due to adverse events, (3) and … serious adverse events. … Regarding withdrawal due to adverse events, the pooled
RR for CBT trials was 0.39 (95% CI, 0.08 to 1.87 … The evidence suggests that suicide-
related harms, serious adverse events, and withdrawal due to ad-
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
March 15, 2009 - Enteric-coated or buffered preparations do not clearly reduce the adverse gastrointestinal effects of … Clinicians should inform patients about the adverse consequences of gastrointestinal bleeding because … increases the risk for major bleeding events in men and women. … The sex-specific meta-analysis of RCTs described above reported adverse events with aspirin use in the … primary prevention of cardiovascular events in 51,342 women and 44,114 men. 3 Major bleeding events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/PdBbRgWKPMbHfeQeHkM242
February 01, 2010 - Adverse effects included elevated
heart rate, elevated blood pressure,
and adverse gastrointestinal effects … Serious adverse
events were reported for 2.7% of the
patients who were taking sibutra-
mine and �1% of … Adverse
events occurred in 3% of the patients
who received orlistat compared with
2% of the patients … They also commonly experi-
enced mild-to-moderate adverse
gastrointestinal effects, with 20% to
30% reporting … Incidence and risk factors for
perioperative adverse respiratory events in
children who are obese.
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/vitamin-d-calcium-combined-supplementation-primary-prevention-falls-fractures-communitydwelling-adults
December 17, 2024 - There were no significant differences in adverse events or serious adverse events in participants randomized … minority of trials reported these outcomes, and ascertainment methods and details provided related to adverse … or serious adverse events varied among trials. 10
Eleven trials reported on the incidence of participants … Two trials compared calcium alone with placebo, but the sample sizes were small and events were rare,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/KdQef_VDT2kmHDX4ddNWmR
August 01, 2022 - isoniazid (RR, 1.50 [95% CI, 1.18-1.89])
and a greater risk of gastrointestinal adverse events (RR, 1.33 … Recent trials also reported on discontinuation due to adverse
events. … There was a statistically nonsignificant increase in discontinu-
ation due to adverse events in a meta-analysis … this was statistically significant in only 1 trial.9,28 Overall, study re-
ports of gastrointestinal adverse … Adverse
events with 4 months of rifampin therapy or 9
months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/suicide-risk-in-adolescents-adults-and-older-adults-screening
May 20, 2014 - Risk factors for suicide attempt include presence of a mental health disorder; serious adverse childhood … Other important risk factors for suicide attempt include serious adverse childhood events; family history … Potential Harms of Screening
Three studies reported on the potential adverse effects of screening … events were documented in the studies. … Few treatment trials in adults reported adverse events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mx2Ko29RH46mTYb36f-UBe
June 20, 2023 - events, even if they have proven
benefits. … events. … Evidence demonstrated an increase in
nonserious harms (defined as any adverse events and withdrawals … due to adverse events). … Serious adverse events were rare and data
were insufficient to determine whether pharmacotherapy
increased
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
January 01, 2017 - and hypopnea events). … Overall, 2% to 47% of par-
ticipants in trials reporting any harms had specific adverse events
while … Across studies that reported any
discontinuation because of adverse events, 7% of patients
using MADs … In general, the adverse events related to CPAP treatment
were likely short-lived and could be alleviated … Adverse effects may limit adherence to treatment.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/t6yV6ZMHngeWgmTsoMMefM
March 01, 2009 - bleeding events, in both men and women. … Aspirin use increases the risk for serious
bleeding events. … The meta-analysis of
RCTs discussed for the key question on benefits (8) re-
ported adverse events with … bleeding events, in both men and women. … without an increased
risk for major bleeding events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/wBcZfBcVp8N3-cyT3Peysv
April 01, 2016 - in effect by age group,
although rare events limited all analyses. … Rationale for a trial of low-dose aspirin for the primary prevention of
major adverse cardiovascular … events and vascular dementia in the
elderly: Aspirin in Reducing Events in the Elderly (ASPREE). … Aspirin effect on the
incidence of major adverse cardiovascular events in patients with
diabetes mellitus … ASCEND: A Study of Cardiovascular Events iN Diabetes [clinical
trial].
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www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-adolescents-and-adults-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
November 20, 2012 - Although the USPSTF found that ART was associated with short-term adverse events and an increased risk … With ART
The 2005 USPSTF review included results from the large, ongoing DAD (Data Collection on Adverse … Friis-Møller N, Sabin CA, Weber R, d'Arminio Monforte A, El-Sadr WM, Reiss P, et al; Data Collection on Adverse … What are the adverse effects (including false-positive results and anxiety) of rapid versus standard … BMI = body mass index; CV = cardiovascular; CVD = cardiovascular disease; DAD = Data Collection on Adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/JcwfLrEqaaxP6DPEQvxgUs
February 18, 2020 - Myalgia is
a commonly reported adverse effect of statins, but placebo-
controlled trial data do not support … prevention of
CVD, statin therapy was not associated with an increased risk of
withdrawal because of adverse … experiencing any serious adverse event. … elevated aminotransferase
levels with statin use.6
Evidence on the association between statin use and adverse … Rosuvastatin to prevent
vascular events in men and women with elevated
C-reactive protein.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2DGd8AvVMTJwP3ttrPcnLL
February 25, 2020 - NRT found a greater num-
ber of headaches, cough, abnormal dreams, muscle pain, and patch-
related adverse … events with NRT.38 Bupropion carries a boxed warn-
ing for increased risk of suicidality in children … events, including suicidality, seizures, inter-
action with alcohol, cardiovascular events, sleepwalking … on benefits be-
cause its follow-up was less than 6 months.50 No difference in se-
rious or severe adverse … withdrew because of adverse events with bupropion.14 Some stud-
ies reported more headaches, cough,
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-and-nicotine-use-prevention-in-children-and-adolescents-primary-care-interventions
April 28, 2020 - however, most quit attempts fail, and about 80% will go on to smoke into adulthood. 36 Immediate adverse … of NRT found a greater number of headaches, cough, abnormal dreams, muscle pain, and patch-related adverse … events with NRT. 38 Bupropion carries a boxed warning for increased risk of suicidality in children … events, including suicidality, seizures, interaction with alcohol, cardiovascular events, sleepwalking … withdrew because of adverse events with bupropion. 14 Some studies reported more headaches, cough,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4zmYnqJXLv8g4LzLrrDDrm
December 01, 2014 - effectiveness
of low-dose aspirin in preventing preeclampsia in women at in-
creased risk and in decreasing adverse … events. … Assessment of Risk for Adverse Effects
Low-dose aspirin use in women at increased risk for
preeclampsia … Eighteen trials reported on the outcome of perinatal
mortality (with 4 smaller studies reporting no events … Seven trials reported adverse events; however, most
were determined to be unrelated to treatment.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/VNs-WaxpPcsodxCb57gYmn
January 03, 2017 - In addition to mortality, other adverse health
outcomes associated with untreated OSA include cardiovascular … mortality independently, beyond the contributions
of age, BMI, and other confounding factors.1 Other adverse … Overall, 2% to 47% of trial participants reported any
adverse effects from treatment with CPAP, including … been
found to be associated with an increased risk of all-cause and car-
diovascular mortality.1 Other adverse … performance; and decreased quality of life.1 However, it is unclear
what role OSA plays in causing these adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-for-abnormal-blood-glucose-and-type-2-diabetes-october-2015
October 26, 2015 - health outcomes is limited, primary prevention that reduces the chances of a diagnosis may reduce the adverse … events. 40
The Diabetes Prevention Program 41 reported no differences in serious or nonserious events … One trial found that acarbose was associated with higher risk for withdrawal because of adverse events … placebo (RR, 1.73 [CI, 1.57 to 1.92]); further, valsartan was associated 44 with hypotension-related adverse … events (RR, 1.16 [CI, 1.11 to 1.23]).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Z6Rfj-qwfoMbuLp-hBmhzS
May 01, 2021 - Jonas, MD, MPH
IMPORTANCE Obstructive sleep apnea (OSA) is associated with adverse health outcomes. … per hour), mod-
erate (16-30 events per hour), and severe (>30 events per hour). … In general, the adverse events related to positive airway pres-
sure treatment were likely short-lived … : overall, too
few events were observed to draw
conclusions
Mortality and
cardiovascular events:
Consistent … Common adverse events included oral or nasal dryness, eye or skin ir-
ritation, and rash.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-97QgoUF_rpQSy-9yM9KCx
November 24, 2020 - Adverse events were rare, with generally no group
differences in serious adverse events, any adverse … events, hospitalizations, musculoskeletal
injuries, or withdrawals due to adverse events. … events or no se-
rious adverse events,55,87,97,118,148,152,247 and other trials reported 1
or more of … the following: serious adverse events, any adverse events,
Table 3. … Adverse events
related to diet and physical activity counseling were exceedingly rare,
with generally