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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vmHooQ6ABG9CagdUXv2_rx
August 25, 2021 - There were no significant differences
in Tanner staging or hormonal adverse events between statin and … years of follow-up in indi-
viduals taking statins compared with control groups.1,17
Studies reporting adverse … tervention trial did not mention harms, and the 3 supplement trials
for FH reported that there were no adverse … Dyslipidemia
In studies including individuals with FH or multifactorial dyslipid-
emia, gastrointestinal adverse … Childhood cardiovascular risk factors and adult
cardiovascular events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/boPWHmzrtxnkkPQAoCNENS
September 18, 2018 - events (treatment-
related harms and discontinuation of medication because of adverse
effects at any … Rates of adverse events were infrequently reported in the be-
havior-based weight loss and weight loss … Weight loss
medications were associated with more adverse events than pla-
cebo, which was associated … with higher dropout rates for adverse
events in the medication groups than in the placebo groups. … Although rates
of serious adverse events were low and generally similar between
groups, participants
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/latent-tuberculosis-infection-screening
May 02, 2023 - There was also a greater risk of treatment discontinuation because of adverse events reported with isoniazid … (RR, 1.50 [95% CI, 1.18-1.89]) and a greater risk of gastrointestinal adverse events (RR, 1.33 [95% … Recent trials also reported on discontinuation due to adverse events. … There was a statistically nonsignificant increase in discontinuation due to adverse events in a meta-analysis … Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
April 11, 2024 - What are the adverse effects of: 3a) risk assessment, 3b) genetic counseling, 3c) genetic testing, and … What are the potential adverse effects of interventions to reduce risk for BRCA1/2 -related cancer in … 3b: Inaccurate risk assessment; inappropriate testing; false-positive and false-negative results; adverse … , and social implications KQ 3c: Inappropriate testing; false-positive and false-negative results; adverse … overdiagnosis, overtreatment, nonadherence); risk-reducing medications (thromboembolic and cardiovascular events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction
September 03, 2019 - , or aromatase inhibitors, to women who are at increased risk for breast cancer and at low risk for adverse … potential benefit of risk reduction of breast cancer must be balanced against the potential harms of adverse … Vasomotor symptoms (hot flashes) are a common adverse effect of both medications. … benefit from risk-reducing medications for breast cancer, as well as evidence on the effectiveness, adverse … Safety and adverse effects associated with raloxifene: multiple outcomes of raloxifene evaluation.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-2007
July 15, 2007 - Adverse effects from lipid-lowering medications and low-fat diets, including potential long-term harms … Adverse effects from lipid-lowering medications and low-fat diets, including potential long-term harms … early identification and lipid-lowering intervention in certain populations of adults can prevent CHD events … however, no studies address the effect of treatment on childhood or adult health outcomes (e.g., CHD events … The adverse effects of long-term use of lipid-lowering agents (e.g., >20 years) have not been studied
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis-june-2019
June 11, 2019 - Limited data suggest that PrEP use is not associated with significant adverse events in adolescents but … There was no clear difference in risk of kidney adverse events when trials were stratified according … serious renal events or withdrawals due to renal events. 31 , 32 Six trials 41 , 42 , 55-58 evaluated … whether renal adverse events while using PrEP were persistent. … The risk of gastrointestinal adverse events increased with both tenofovir disoproxil fumarate monotherapy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-KMSTWRT9xbm7spaqDq_GE
February 12, 2019 - They reported only the
number of events for 1 of the 11 adverse effects collected; constipa-
tion differed … events (but data were not shown). … No harms were associated with omega-3 fatty acids, although
reports of adverse events were collected … events were reported in either treatment
group
Consistency NA,
imprecise
Low (DHA)
Nortriptyline … events such as conversion
to mania
Insufficient Conducted in the United States
Abbreviations: DHA,
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2_e9yUNkzrtkkNKmn7YtCU
September 01, 2012 - cardiovascular
events. … None of the studies reviewed was designed to detect
adverse effects of interventions to promote a healthful … The adverse effects of
these counseling interventions were also reviewed. … events. … Because the USPSTF determined that there
were few if any adverse effects of these counseling interven
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chronic-obstructive-pulmonary-disease-screening-2016
April 05, 2016 - Adverse effects were generally mild (eg, dry mouth and cough). … event or serious adverse events were mixed but generally showed few differences between treated and … events. … events in both groups; 1 study reported higher rates of any adverse event in the tiotropium group compared … Possible protection by inhaled budesonide against ischaemic cardiac events in mild COPD.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary6/osteoporosis-screening-2011
July 06, 2010 - Bisphosphonates are not consistently associated with serious adverse events; raloxifene and estrogen … increase thromboembolic events; and estrogen causes additional adverse events. … differences with placebo in rates of serious gastrointestinal adverse events 107 , 108 or withdrawals … events. … Upper gastrointestinal adverse events and cyclical etidronate. Am J Med 1997;103:462-7.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vAKRuLQRL2T7_DHsgFzW_q
Risk factors for suicide attempt include presence of a mental health disorder; serious
adverse childhood … events; family history of suicide; prejudice or discrimination associated with being lesbian, gay, bisexual
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-dyslipidemia/statin-use-in-adults-preventive-medication-november-2016
November 13, 2016 - Studies of individuals with prior cardiovascular events were excluded. … Although statins in middle-aged and older adults appear to be relatively safe and short-term adverse … events generally resolve with discontinuation of therapy, long-term adverse effects of statins started … Long-term intraindividual cholesterol variability: natural course and adverse impact on morbidity and … function tests or creatine phosphokinase levels, and others as identified in the literature)
KQ 6: Other adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4y3P9DxovKMEjNmVd2mrPp
December 01, 2007 - events from the test, the accuracy and
potential for adverse events of any subsequent confirmatory
diagnostic … to screen
(the number of people who would need to be screened for
some defined period to prevent 1 adverse … to harm (the
number of people who would need to be treated or screened
for a defined time to cause 1 adverse … benefits and harms
can be challenging—benefits are often quantified in terms
of lives extended or illness events … For
example, the benefits of prophylactic aspirin therapy
among men include fewer coronary heart events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/3Kwu7j_WfCFQSnSzqrDWwt
June 20, 2019 - benefit from risk-reducing medications for breast
cancer, as well as evidence on the effectiveness, adverse … , or aromatase inhibitors,
to women who are at increased risk for breast cancer and at low risk for adverse … , or aromatase
inhibitors, to women who are at increased risk for breast cancer and
at low risk for adverse … Vasomotor symptoms (hot
flashes) are a common adverse effect of both medications. … Safety and adverse effects associated with
raloxifene: multiple outcomes of raloxifene
evaluation.
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/benefit.pdf
December 01, 2007 - events from the test, the accuracy and
potential for adverse events of any subsequent confirmatory
diagnostic … to screen
(the number of people who would need to be screened for
some defined period to prevent 1 adverse … to harm (the
number of people who would need to be treated or screened
for a defined time to cause 1 adverse … benefits and harms
can be challenging—benefits are often quantified in terms
of lives extended or illness events … For
example, the benefits of prophylactic aspirin therapy
among men include fewer coronary heart events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening-june-2018
June 26, 2018 - The USPSTF found that the risk of serious adverse events, upper gastrointestinal events, or cardiovascular … Clinicians should educate patients on how to minimize the adverse effects of drug therapies, such as … events (RR, 0.98 [95% CI, 0.92-1.04]; 17 studies; n = 11,745), or upper gastrointestinal events (RR, … events, and upper gastrointestinal events. … Pooled analyses showed no increased risk of discontinuation due to adverse events (RR, 1.12 [95% CI,
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2008
June 15, 2008 - USPSTF reviewed the evidence on early treatment of type 2 diabetes mellitus in preventing long-term adverse … Potential Harms of Screening and Treatment: Observational studies report no serious long-term adverse … No studies reported adverse effects of receiving a diagnosis of IFG or IGT, and no studies examined the … agents. 15 Angiotensin-converting enzyme inhibitors and statins have reasonably low levels of serious adverse … The relationship between glucose and incident cardiovascular events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ERAa_Bwr7hQxqZZ-X3p8Qh
May 10, 2022 - events. … 2
What are the adverse effects of COPD treatments in this population? … events. … 588)
Initiation of a LAMA or LABA is
associated with an increase in
risk of serious cardiovascular
events … None of the included trials
that reported adverse effects found significant harms.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-obstructive-pulmonary-disease-screening
October 08, 2020 - What are the adverse effects of COPD treatments in this population? … disease-specific mortality, and COPD-related morbidity; HRQoL at ≥6 months followup
KQ 3: Serious adverse … events requiring unexpected or unwanted medical attention and/or resulting in death (e.g., requiring