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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
April 25, 2024 - the comparative performance and agreement between PREVENT (Predicting Risk of cardiovascular disease EVENTs … addition to other risk factors (KQs 1, 3 only)
KQs 4, 5: Interventions aimed at preventing CVD events … placebo
Models predicting mortality only or heart failure only
Outcomes
KQs 1, 4: CVD events … (e.g., myocardial infarction, stroke) and mortality KQ1a: In trials also reporting CVD events, the … , agreement between observed and predicted risks), and decision curve analysis
KQs 3, 5: Serious adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/xt2Uhv4qyLUZ8o2HB_a4YQ
July 01, 2013 - events; however,
many of these events are transient or self-limited, and ef-
fective alternatives can … events, including meta-
bolic disturbances associated with an increased risk for car-
diovascular events … However,
the early treatment group in the HPTN 052 study had
ART-related adverse events more frequently … The 2005 USPSTF review included results from the large,
ongoing DAD (Data Collection on Adverse Events … Common adverse effects of antiretroviral therapy for HIV disease.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/breast-cancer-screening
April 30, 2024 - Adverse events related to the supplemental MRI screening reported in the trial included 5 classified … as serious adverse events (2 vasovagal reactions and 3 allergic reactions to the contrast agent) and … Twenty-seven participants (0.6% of the MRI group) reported a serious adverse event within 30 days of … events: 1 RCT (n = 99,634) reported the same number of adverse events for both screening tests (DBT/ … events: RCT reported 8 adverse events (5 serious) during or immediately after MRI—vasovagal reactions
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
November 24, 2020 - Adverse events were rare, with generally no group differences in serious adverse events, any adverse … events, hospitalizations, musculoskeletal injuries, or withdrawals due to adverse events. … events or no serious adverse events, 55 , 87 , 97 , 118 , 148 , 152 , 247 and other trials reported … 1 or more of the following: serious adverse events, any adverse events, hospitalizations, musculoskeletal … significant differences in any study for serious adverse events, any adverse events, hospitalizations
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/obstructive-sleep-apnea-in-adults-screening
November 15, 2022 - men and 6% for women. 1 Severe OSA is associated with increased all-cause mortality. 2 , 3 Other adverse … In general, mild OSA is defined as 5 to 15 events per hour, moderate OSA as 16 to 30 events per hour, … alternative therapy to positive airway pressure for patients with OSA who prefer them or for those with adverse … to the increase in prevalence of obesity. 1 , 2 Obstructive sleep apnea is associated with multiple adverse … , mucosal erosions, and jaw or temporomandibular joint pain or discomfort. 15 , 16 In general, the adverse
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-viii-standardization-outcome-tables
July 01, 2017 - Adverse events/states.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2XRG8Dz2EegVWYUrRThgmD
October 01, 2015 - None of the drugs were
associated with major cardiovascular adverse events. … Adverse Events
One review reported minor adverse events related
to ear acupuncture, ear acupressure, … Although more serious
adverse events occurred in the nicotine e-cigarette
group (27 events [19.7%]) than … Adverse Events
None of the reviews on behavioral interventions
among pregnant women reported adverse … Adverse events
associated with nicotine replacement therapy (NRT) for smoking ces-
sation.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-b-virus-infection-screening-nonpregnant-adolescents-adults-may-2014
June 18, 2014 - However, trials found no difference in the risk for serious adverse events or the number of participants … In addition, most antiviral adverse events are self-limited with discontinuation of therapy. … events (12 trials; RR, 0.8 [CI, 0.6 to 1.1]; I 2 = 0%) or any adverse event (7 trials; RR, 0.96 [CI … Studies did show an increased risk for withdrawal due to adverse events (9 trials; RR, 4.0 [CI, 1.4 to … events (RR, 2.1 [CI, 1.0 to 4.5]; I 2 = 0%), withdrawals due to adverse events (RR, 7.6 [CI, 1.1 to
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
August 23, 2022 - Statin therapy was not significantly associated with increased risk of serious adverse events (RR, 0.97 … to 1.26%]) (eFigure 9 in the JAMA Supplement), serious adverse events (10 trials, n = 55,419; RR, … events, serious adverse events, cancer, or elevated liver enzyme levels vs placebo or no statin therapy … events or muscle symptoms, these findings could be due to expectations regarding adverse effects and … Statin safety and associated adverse events: a scientific statement from the American Heart Association
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obstructive-sleep-apnea-in-adults-screening
November 15, 2022 - Adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular … men and 6% for women. 1 Severe OSA is associated with increased all-cause mortality. 2 , 3 Other adverse … In general, mild OSA is defined as 5 to 15 events per hour, moderate OSA as 16 to 30 events per hour, … to the increase in prevalence of obesity. 1 , 2 Obstructive sleep apnea is associated with multiple adverse … , mucosal erosions, and jaw or temporomandibular joint pain or discomfort. 15 , 16 In general, the adverse
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/DYFdTVu-UY3h7CWGdA7Zkh
July 20, 2021 - A register-based study: adverse events in
colonoscopies performed in Sweden 2001-2013. … Patient-reported adverse events after colonoscopy
in Norway. … Adverse events after outpatient colonoscopy in the
Medicare population. … Adverse events
after screening and follow-up colonoscopy. … Adverse
events of computed tomography colonography: an
Italian National Survey.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/WEqCV3NvnZAeLdC_pp6nVK
October 01, 2018 - events (1.9%) and withdrawal due to
adverse events (0.4%). … due to adverse
events, headache, or fatigue. … to adverse events (RR, 0.06
[95% CI, 0.01 to 0.29]; I2 = 0%; ARD, −9% [95% CI, −14% to −3%])
vs the … ) (eFigure 5 in the
Supplement) and withdrawal due to adverse events (44 studies,
n = 8060; 0.4% [95% … rates for specific adverse events ranged from 2.4% (anemia) to 18.7%
(headache) (eTables 12 and 13 in
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2002
July 08, 2002 - that clinicians discuss chemoprevention with women at high risk for breast cancer and at low risk for adverse … The USPSTF found good evidence that tamoxifen and raloxifene increase the risk for thromboembolic events … Risk for adverse effects. … Women are at lower risk for adverse effects from chemoprevention if they are younger; have no predisposition … to thromboembolic events such as stroke, pulmonary embolism, or deep venous thrombosis; or do not have
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/zk8YxjaQxLGUTtt__nBQB_
September 09, 2021 - There was also evidence of an in-
creased risk of serious adverse events with use of selective seroto … events appears to be relatively low, how-
ever, and evidence for specific serious adverse events was … The study
of lithium found a higher rate of nonserious adverse events (75.7%
with lithium, 69.0% with … ,
34.1% with placebo; P value not reported) but no difference in with-
drawals due to adverse events … events with all
agents examined and a higher risk of serious adverse
events with SSRI use (OR, 1.39
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002
January 01, 2002 - Enteric-coated or buffered preparations do not clearly reduce adverse gastrointestinal effects of aspirin … Most events occur in older people and those with recognized risk factors for cardiovascular disease, … physicians and patients balance the reduced rate of nonfatal myocardial infarction against potential adverse … Aspirin for the primary prevention of cardiovascular events: recommendations and rationale. … Aspirin for the primary prevention of cardiovascular events: A summary of the evidence for the U.S.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screening-june-2018
June 26, 2018 - adverse events (23.8% vs 23.9%; RR, 1.12 [95% CI, 0.88-1.44]; I 2 = 14.1%; 4 RCTs [8663 participants … events, and upper GI tract events
Consistent and precise for discontinuations, serious adverse events … events, and upper gastrointestinal events; insufficient for cardiovascular events, osteonecrosis, and … Insufficient for discontinuation; low for no harm for serious adverse events and serious infections … c Pooled estimates include men, women, and combined estimates (1 study did not provide adverse events
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/R_cAa3AjFGQ2np_aQnzQGA
February 11, 2025 - Compared with placebo, no statistically significant associations were observed
for adverse events. … events. … events, se-
rious adverse events, or gastrointestinal adverse events are shown
in Figure 4. … KQ5: Harms of treatment
Bisphosphonates
Discontinua-
tions due to
adverse events
27 RCTs160-168,170,172,173,175,180 … events and serious adverse events and
moderate for no effect on upper gastrointestinal adverse events
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
January 14, 2025 - Compared with placebo, no statistically significant associations were observed for adverse events. … events, serious adverse events, or gastrointestinal adverse events are shown in Figure 4 . … events and serious adverse events and moderate for no effect on upper gastrointestinal adverse events … for bisphosphonates and low for increased upper gastrointestinal adverse events for denosumab. … KQ5: Harms of treatment
Bisphosphonates
Discontinuations due to adverse events
27
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary21/depression-in-children-and-adolescents-screening-2009
March 15, 2009 - events. … we calculated pooled absolute RDs for suicide-related adverse events (SREs) using data for a subset … Treatment-emergent adverse events from selective serotonin reuptake inhibitors by age group: Children … Suicidal adverse events in pediatric randomized, controlled clinical trials of antidepressant drugs are … To incorporate more conservative estimates of adverse events into the review, we included results from
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-for-prediabetes-and-type-2-diabetes
August 24, 2021 - Most trials reporting mortality or CVD events over a follow-up duration of 6 years or less had few events … Categories and definitions used for adverse events were heterogenous across studies, and few trials ( … 3 trials) reported adverse events beyond 5 years of follow-up. 65 , 66 , 74 Five trials reported rates … Four studies of lifestyle interventions reported on musculoskeletal-related adverse events, 2 found no … Six pharmacologic trials found higher rates of GI adverse events vs controls: metformin (3 trials), acarbose