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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Xbtq4oDQwVo7KgmSjnnDbz
November 01, 2021 - Serious adverse events from colonoscopy in
asymptomatic persons included perforations (4/10 000 procedures … No studies reported
serious adverse events
in persons without CTC. … Adverse
events of computed tomography colonography: an
Italian National Survey. … Adverse events
after screening and follow-up colonoscopy. … Adverse events after outpatient colonoscopy in the
Medicare population.
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/breast-cancer-medication-use-reduce-risk
December 28, 2023 - status) and DCIS; breast cancer mortality; all-cause mortality; and quality of life
KQ 2 (Harms): Adverse … health outcomes
Fractures
Ophthalmologic disorders
Genitourinary outcomes
Thromboembolic events … Cardiovascular events
Risk of other cancers
Adverse outcomes related to quality of life
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/falls-prevention-community-dwelling-older-adults-interventions
April 21, 2022 - interventions to prevent falls in community dwelling older adults at average or increased risk result in any adverse … Get Up & Go Test, 6-meter timed walk, Functional Reach Test, and Berg Balance Scale)
KQ 2: Minor adverse … events that are reported using nonvalidated, nongeneralizable measures
Followup
Minimum of
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary27/breast-cancer-medications-for-risk-reduction-2013
April 15, 2013 - adverse effects. … events, uterine abnormalities, cataracts, and other adverse effects. … Two other studies also described concerns about adverse effects 67 , 71 . … events, than women younger than 50 years. … events and ≤4% for nonprotocol specified events).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qh7NQD6ZEynjyRso7L5-gS
January 15, 2008 - Several clinical trials of pharmacotherapy for drug misuse
have reported mild to serious adverse events … , although some of these events
were likely related to underlying drug use. … The specific adverse events noted to
occur more frequently in the treatment arm of trials (compared … Adverse events ranging from mild (e.g., elevated liver function tests) to
serious (e.g., seizures) have … The adverse events reported more frequently in the treatment arm of trials
(compared to placebo) have
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/drug-use-illicit-screening-january-2008
January 15, 2008 - Several clinical trials of pharmacotherapy for drug misuse have reported mild to serious adverse events … , although some of these events were likely related to underlying drug use. … The specific adverse events noted to occur more frequently in the treatment arm of trials (compared to … Adverse events ranging from mild (e.g., elevated liver function tests) to serious (e.g., seizures) have … The adverse events reported more frequently in the treatment arm of trials (compared to placebo) have
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-depression-suicide-risk-children-adolescents
October 11, 2022 - or stress, bullying, maltreatment, adverse life events, and a difficult relationship with parents. … , bullying (either as perpetrators or as victims), adverse life events, early exposure to stress, maltreatment … events and serious adverse events compared with placebo; the differences were not statistically significant … , likely because of a small number of events due to poor reporting. … There were no significant differences in adverse events reported. 1 , 2
Response to Public Comment
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/latent-tuberculosis-infection-adults
November 22, 2022 - There was also a greater risk of treatment discontinuation because of adverse events reported with INH … (RR, 1.50 [95% CI, 1.18 to 1.89]) and a greater risk of gastrointestinal adverse events (RR, 1.33 [95% … Recent trials also reported on discontinuation due to adverse events. … INH alone reported increased discontinuation due to adverse events in study participants in the RPT+INH … Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/v1-breast-cancer-medications-for-risk-reduction--s
May 06, 2002 - The number of adverse events, for example, would likely be higher in women with hypertension or other … Adverse events would be lower in subgroups with no predisposition to thromboembolic events and in women … Return to Table of Contents
Table 3: Adverse events in 4 randomized controlled trials of breast … Do chemopreventive agents increase the risk of adverse effects? … The adverse effects of treatment are also well documented.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction-2002
May 06, 2002 - The number of adverse events, for example, would likely be higher in women with hypertension or other … Adverse events would be lower in subgroups with no predisposition to thromboembolic events and in women … Return to Table of Contents
Table 3: Adverse events in 4 randomized controlled trials of breast … Do chemopreventive agents increase the risk of adverse effects? … The adverse effects of treatment are also well documented.
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www.uspreventiveservicestaskforce.org/uspstf/reconsidering-approach-prevention-recommendations-older-adults-figure-2
December 01, 2010 - interventions to reduce falls and fall-related outcomes
Figure 2 is an analytic framework that depicts the events … Risk Evaluation, Intervention, Intermediate Outcomes, Health Outcomes, Other Positive Outcomes, and Adverse … Minor adverse outcomes associated with specific interventions include: increased fall-related outpatient … KQ3: What are the adverse effects associated with interventions to reduce falls?
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/prevention-human-immunodeficiency-virus-hiv-infection-prep
November 04, 2021 - *Harms also include renal dysfunction, adverse … with antiretroviral drug-resistant HIV, gastrointestinal harms, headaches, and discontinuation due to adverse … events.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-adults-interventions
September 18, 2018 - events (treatment-related harms and discontinuation of medication because of adverse effects at any … The data on health outcomes (KQ1) and adverse events (KQ3) did not allow for quantitative pooling because … Rates of adverse events were infrequently reported in the behavior-based weight loss and weight loss … higher dropout rates for adverse events in the medication groups than in the placebo groups. … Although rates of serious adverse events were low and generally similar between groups, participants
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-b-virus-infection-screening
December 15, 2020 - Pooled analyses found no significant differences in the risk of serious adverse events (4 trials; RR, … 0.92 [95% CI, 0.45-1.85]), any adverse event (5 trials; RR, 1.01 [95% CI, 0.90-1.11]), renal adverse … events (3 trials; RR, 1.27 [95% CI, 0.31-3.55]), or study withdrawal due to adverse events (3 trials … No significant differences in risk of serious adverse events or withdrawal due to adverse events were … receiving placebo or no treatment, and that some adverse events resolve after discontinuing therapy.
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/tobacco-smoking-cessation-in-adults-including-pregnant-women-interventions
March 15, 2018 - outcomes ) : Tobacco cessation/tobacco abstinence (continuous or point prevalence abstinence)
KQ 3 (adverse … events):
Serious treatment-related harms at any time point after the intervention began
Weight gain … e.g., worsening of symptoms such as depression, anxiety, psychosis; loss of associates or friends)
Adverse … events associated with medications
Paradoxical increase in tobacco use
Demoralization due to failed
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/glaucoma-screening-adults-older-adults
October 26, 2021 - There were no significant differences in risk of serious adverse events (RR, 1.14, [95% CI, 0.60 to 1.99 … ]; I 2 =32%; 3 trials; n=3,140), withdrawal due to adverse events (RR, 2.40, [95% CI, 0.71 to 19.32] … ; I 2 =0%; 5 trials; n=648), or any adverse event (RR, 1.56, [95% CI, 0.59 to 4.03]; I 2 =82%; 2 trials … ; n=1,538). 9 Two trials found that treatment was associated with increased risk of ocular adverse events … and serious adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/primary-angle-glaucoma-screening
October 26, 2021 - There were no significant differences in risk of serious adverse events (RR, 1.14, [95% CI, 0.60 to 1.99 … ]; I 2 =32%; 3 trials; n=3,140), withdrawal due to adverse events (RR, 2.40, [95% CI, 0.71 to 19.32] … ; I 2 =0%; 5 trials; n=648), or any adverse event (RR, 1.56, [95% CI, 0.59 to 4.03]; I 2 =82%; 2 trials … ; n=1,538). 9 Two trials found that treatment was associated with increased risk of ocular adverse events … and serious adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/breast-cancer-medication-use-reduce-risk
March 21, 2024 - breast cancer mortality; all-cause mortality; and global measures of quality of life
KQ 2 (Harms): Adverse … not limited to:
Fractures
Ophthalmologic disorders
Genitourinary outcomes
Thromboembolic events … Cardiovascular events
Risk of other cancers
Adverse outcomes related to quality of life
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/update-methods-estimating-certainty-and-magnitude-net-benefit
April 01, 2019 - into account the false-positive and false-negative rates of the screening test, the possibility of adverse … events from the test, the accuracy and potential for adverse events of any subsequent confirmatory diagnostic … caused
18 events prevented
Angiography confirmation
55 events caused
106 events prevented … MRA confirmation
23 events caused
217 events prevented
NNS to prevent 1 stroke over 5 years … No confirmatory test
Events caused > prevented
5,556
Angiography confirmation
Events caused
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening-2013
April 15, 2013 - events; however, many of these events are transient or self-limited, and effective alternatives can … events, including metabolic disturbances associated with an increased risk for cardiovascular events … However, the early treatment group in the HPTN 052 study had ART-related adverse events more frequently … The 2005 USPSTF review included results from the large, ongoing DAD (Data Collection on Adverse Events … Common adverse effects of antiretroviral therapy for HIV disease.