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Showing results for "adverse events".
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121. Archived: Evidence Summary: Screening for Dyslipidemia in Younger Adults: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-dyslipidemia/statin-use-in-adults-preventive-medication-november-2016
     November 13, 2016 - Studies of individuals with prior cardiovascular events were excluded. … Although statins in middle-aged and older adults appear to be relatively safe and short-term adverse … events generally resolve with discontinuation of therapy, long-term adverse effects of statins started … Long-term intraindividual cholesterol variability: natural course and adverse impact on morbidity and … function tests or creatine phosphokinase levels, and others as identified in the literature) KQ 6: Other adverse

122. Final Research Plan: Abdominal Aortic Aneurysm: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/abdominal-aortic-aneurysm-screening
     November 30, 2017 - aneurysm-related mortality, cardiovascular disease mortality, aneurysm rupture rate, cardiovascular disease events … aneurysm-related mortality, cardiovascular disease mortality, aneurysm rupture rate, cardiovascular disease events … , and quality of life KQ 5: Harms (i.e., serious adverse events from pharmacotherapy or surgery) … response to comments, the USPSTF expanded the scope of the evidence review to include cardiovascular events

123. Archived: Evidence Summary: Chronic Obstructive Pulmonary Disease: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chronic-obstructive-pulmonary-disease-screening-2016
     April 05, 2016 - Adverse effects were generally mild (eg, dry mouth and cough). … event or serious adverse events were mixed but generally showed few differences between treated and … events. … events in both groups; 1 study reported higher rates of any adverse event in the tiotropium group compared … Possible protection by inhaled budesonide against ischaemic cardiac events in mild COPD.

124. Screening for Chronic Obstructive Pulmonary Disease: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/ERAa_Bwr7hQxqZZ-X3p8Qh
     May 10, 2022 - events. … 2 What are the adverse effects of COPD treatments in this population? … events. … 588) Initiation of a LAMA or LABA is associated with an increase in risk of serious cardiovascular events … None of the included trials that reported adverse effects found significant harms.

125. Update on the Methods of the U.S. Preventive Services Task Force: Estimating Certainty and Magnitude of Net Benefit (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4y3P9DxovKMEjNmVd2mrPp
     December 01, 2007 - events from the test, the accuracy and potential for adverse events of any subsequent confirmatory diagnostic … to screen (the number of people who would need to be screened for some defined period to prevent 1 adverse … to harm (the number of people who would need to be treated or screened for a defined time to cause 1 adverse … benefits and harms can be challenging—benefits are often quantified in terms of lives extended or illness events … For example, the benefits of prophylactic aspirin therapy among men include fewer coronary heart events

126. Screening for Suicide Risk in Adolescents, Adults, and Older Adults in Primary Care: Clinical Summary of USPSTF Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/vAKRuLQRL2T7_DHsgFzW_q
     Risk factors for suicide attempt include presence of a mental health disorder; serious adverse childhood … events; family history of suicide; prejudice or discrimination associated with being lesbian, gay, bisexual

127. Archived: Diabetes Mellitus (Type 2) in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2008
     June 15, 2008 - USPSTF reviewed the evidence on early treatment of type 2 diabetes mellitus in preventing long-term adverse … Potential Harms of Screening and Treatment: Observational studies report no serious long-term adverse … No studies reported adverse effects of receiving a diagnosis of IFG or IGT, and no studies examined the … agents. 15 Angiotensin-converting enzyme inhibitors and statins have reasonably low levels of serious adverse … The relationship between glucose and incident cardiovascular events.

128. Update on the Methods of the U.S. Preventive Services Task Force: Estimating Certainty and Magnitude of Net Benefit (pdf file)
     www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/benefit.pdf
     December 01, 2007 - events from the test, the accuracy and potential for adverse events of any subsequent confirmatory diagnostic … to screen (the number of people who would need to be screened for some defined period to prevent 1 adverse … to harm (the number of people who would need to be treated or screened for a defined time to cause 1 adverse … benefits and harms can be challenging—benefits are often quantified in terms of lives extended or illness events … For example, the benefits of prophylactic aspirin therapy among men include fewer coronary heart events

129. Screening for Lipid Disorders in Children: Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/BwAo_shwmJLSRguyWxaXpP
     July 01, 2007 - Adverse effects from lipid-lowering medications and low-fat diets, including potential long-term harms … abnormal lipid levels have been strongly associated with the risk of coronary heart disease (CHD) events … reduction in 4 studies). 2 Harms of Screening and Treatment There is poor-quality evidence on the adverse … treatment is based on 81 controlled and non-controlled studies of treatment that reported a variety of adverse … The adverse effects of long-term use of lipid-lowering agents (eg, >20 years) have not been studied.

130. Archived: Obesity in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-2010
     January 15, 2010 - Adverse effects included elevated heart rate, elevated blood pressure, and adverse gastrointestinal effects … An examination of the literature on the harms of weight-management programs found no evidence of adverse … Serious adverse events were reported for 2.7% of the patients who were taking sibutramine and <1% of … Adverse events occurred in 3% of the patients who received orlistat compared with 2% of the patients … Incidence and risk factors for perioperative adverse respiratory events in children who are obese.

131. Evidence Summary: Chronic Obstructive Pulmonary Disease: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chronic-obstructive-pulmonary-disease-screening
     May 10, 2022 - events. … None of the included treatment trials that reported adverse effects found significant harms. … events. … None of the included trials that reported adverse effects found significant harms. … 242,588) Initiation of a LAMA or LABA is associated with an increase in risk of serious cardiovascular events

132. Zr66Ep5Abbqcuqy7Ktdetn (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZR66ep5ABbQCUQy7KTDETn
     July 01, 2014 - However, trials found no difference in the risk for serious adverse events or the number of participants … In addition, most antiviral adverse events were self-limited with discontinuation of therapy. … events (12 trials; RR, 0.8 [CI, 0.6 to 1.1]; I2 � 0%) or any adverse event (7 trials; RR, 0.96 [CI, … Studies did show an increased risk for withdrawal due to adverse events (9 trials; RR, 4.0 [CI, 1.4 to … events (RR, 2.1 [CI, 1.0 to 4.5]; I2 � 0%), with- drawals due to adverse events (RR, 7.6 [CI, 1.1 to

133. Interventions to Prevent Perinatal Depression: Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/-KMSTWRT9xbm7spaqDq_GE
     February 12, 2019 - They reported only the number of events for 1 of the 11 adverse effects collected; constipa- tion differed … events (but data were not shown). … No harms were associated with omega-3 fatty acids, although reports of adverse events were collected … events were reported in either treatment group Consistency NA, imprecise Low (DHA) Nortriptyline … events such as conversion to mania Insufficient Conducted in the United States Abbreviations: DHA,

134. Archived: Evidence Summary: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary17/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
     December 15, 2013 - Women using tamoxifen and raloxifene had more thromboembolic events than women using placebo (tamoxifen … Coronary heart disease events and stroke were not increased in placebo-controlled trials, although women … Few studies described adverse effects. … In trials, tamoxifen and raloxifene increased thromboembolic events and tamoxifen increased endometrial … Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women.

135. Draft Recommendation: Intimate Partner Violence and Caregiver Abuse of Older or Vulnerable Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/intimate-partner-violence-abuse-older-vulnerable-adults
     October 29, 2024 - with the control group. 1 In one study, IPV victimization was lower in the intervention group (7.50 events … per person-year) compared with the control group (9.55 events per person-year) at 3 years, but the difference … was not statistically significant (incident rate ratio of average IPV events per person-year, 0.86 [ … events; however, it was unclear whether events were prespecified or how they were monitored. 1 , 51 … events related to study participation by women. 1 , 49 Other trials also reported no harms associated

136. Archived: Osteoporosis to Prevent Fractures: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening-june-2018
     June 26, 2018 - The USPSTF found that the risk of serious adverse events, upper gastrointestinal events, or cardiovascular … Clinicians should educate patients on how to minimize the adverse effects of drug therapies, such as … events (RR, 0.98 [95% CI, 0.92-1.04]; 17 studies; n = 11,745), or upper gastrointestinal events (RR, … events, and upper gastrointestinal events. … Pooled analyses showed no increased risk of discontinuation due to adverse events (RR, 1.12 [95% CI,

137. Screening for Intimate Partner Violence and Caregiver Abuse of Older or Vulnerable Adults: US Preventive Services Task Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_q6ZTL2Yg6f6rLp-Re9whD
     June 24, 2025 - were lower in the intervention group (7.50 events per person-year) compared with Clinical Review & … the control group (9.55 events per person-year) at 3 years, but the difference was not statistically … significant (incident rate ratio of average IP V events per person-year, 0.86 [95% CI, 0.73-1.01]).47 … events; however, it was unclear whether events were prespecified or how they were monitored.1,35,54 … events related to study participation by women.1,35,52 Other trials also re- ported no harms associated

138. Archived: Final Evidence Summary: Healthy Diet and Physical Activity: Counseling for CVD Prevention in Adults | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary27/healthy-diet-and-physical-activity-counseling-for-cvd-prevention-in-adults-2012
     December 15, 2010 - Key Question 4: Harms Adverse effects were rarely noted in physical activity counseling trials. … We found no studies designed to assess the adverse effects of dietary counseling or the adverse effects … None of the healthful diet counseling trials reported specific adverse events.   … However, the absolute risk for serious cardiac events related to physical activity seems very small. … events not reported in trials Good Good No specific examination of adverse effects

139. Screening for Chronic Obstructive Pulmonary Disease: Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/BhnZRA--TRpXdg9_tYmZ_M
     April 05, 2016 - Adverse effects were generally mild (eg, dry mouth and cough). … event or serious adverse events were mixed but generally showed few differences between treated and … events. … events in both groups; 1 study re- ported higher rates of any adverse event in the tiotropium group … Possible protection by inhaled budesonide against ischaemic cardiac events in mild COPD.

140. Archived: Final Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary4/colorectal-cancer-screening-2008
     October 15, 2008 - Duration of follow-up and methods for determining adverse events varied. … No significant statistical heterogeneity in pooling estimates of serious adverse events. … Duration of follow-up and methods for determining adverse events varied. … No significant statistical heterogeneity in pooling estimates of serious adverse events. … findings considered separate from serious adverse events CCT = controlled clinical trial; CRC