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  1. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/screening-depression-suicide-risk-adults
    September 20, 2022 - This trial was among postpartum patients and no adverse events were reported in the intervention and … Harm outcomes included any adverse events, dropout due to adverse events, serious adverse events, suicide … There was also an increased risk of serious adverse events with SSRI use compared with placebo (OR, 1.39 … The absolute risk of serious adverse events appears to be relatively low, and evidence for specific serious … adverse events was very limited.
  2. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/blood-pressure-in-children-and-adolescents-hypertension-screening
    November 01, 2018 - What are the adverse effects, such as labeling and anxiety, of screening for high blood pressure in children … What are the adverse effects of drug, nondrug, and combination interventions for treating high blood … What are the effectiveness and adverse effects of drug, nondrug, and combination interventions for treating … Hypertension-related outcomes): Severe visual impairment End-stage renal disease Cardiovascular events … , including ischemic heart disease and heart failure Cerebrovascular events, including hemorrhagic
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/KFZpoMBYuoo8TRW6nhRev8
    October 23, 2023 - health outcomes Adverse events Event-driven vs daily oral PrEPb ADAPT/HPTN 067 Bekker et al,12 2018 … Clinical health outcomes Adverse events Long-acting injectable cabotegravir vs daily oral TDF/FTC … All adverse events were grade 1 except in 1 patient with grade 2 symptoms. … events or grade 3 or higher adverse events (Table 2; eTables 1-4 in the Supplement).6,7 There were also … adverse events, or STIs.
  4. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
    March 14, 2019 - improvements in intermediate outcomes as a result of antiviral treatment and reduction in risk of HBV-related adverse … outcomes as a result of antiviral treatment of chronic HBV infection and reduction in risk of HBV-related adverse … HBsAg or acquisition of anti-HBs) KQ 6: Harms of antiviral medications Withdrawals due to adverseevents Serious adverse events KQ 4: Drug resistance; development of mutations or antibodies
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/lipid-disorders-in-children-screening
    July 18, 2023 - Limited longer-term evidence shows few withdrawals due to adverse events, slightly higher rates of liver … events. … y with FH Ezetimibe 1 (n = 138) New: 0 Similar rates of total adverse events in intervention … (simvastatin + ezetimibe) 1 (n = 248) New: 0 Similar rates of total adverse events in intervention … and control groups Consistency NA, imprecise High total adverse events in both the intervention
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/KbJjfcaP9XvhkP43u-7b9q
    July 01, 2014 - , but risk for serious adverse events did not differ. … events, serious adverse events, or overall adverse events). … events (RR, 2.1 [CI, 1.0 to 4.5]; I2 � 0%), withdrawals due to adverse events (RR, 7.6 [CI, 1.1 to 52 … but not with increased risk for serious adverse events. … events compared with lamivudine (54, 55), consistent with the high prevalence of adverse events with
  7. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/weight-loss-prevent-obesity-related-morbidity-mortality
    May 18, 2023 - KQ 1: Health outcomes: All-cause and cardiovascular disease mortality Cardiovascular disease events … mellitus Hypertension Dyslipidemia Cardiorespiratory fitness measures KQ 3: Harms: Any adverse … treatment-related harm after initiation of the intervention, including: Any adverse event or serious … adverse event Withdrawals or discontinuation of medication due to adverse effects Unhealthy weight
  8. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/behavioral-counseling-interventions-promote-healthy-diet-physical-activity-weight-loss-prevent-cardiovascular-disease-adults
    May 18, 2023 - KQ 1: Health outcomes: All-cause and cardiovascular disease mortality Cardiovascular disease events … mellitus Hypertension Dyslipidemia Cardiorespiratory fitness measures KQ 3: Harms: Any adverse … treatment-related harm after initiation of the intervention, including: Any adverse event or serious … adverse event Withdrawals or discontinuation of medication due to adverse effects Unhealthy weight
  9. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/colorectal-cancer-screening
    May 18, 2021 - A register-based study: adverse events in colonoscopies performed in Sweden 2001-2013. … Patient-reported adverse events after colonoscopy in Norway. … Adverse events after outpatient colonoscopy in the Medicare population. … Adverse events after screening and follow-up colonoscopy. … Adverse events of computed tomography colonography: an Italian National Survey.
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF_Y9vcT3eNPdHjTxPZsUZ
    April 17, 2023 - This trial was among postpartum patients, and no adverse events were re- ported in the intervention … Harm outcomes included any adverse events, dropout due to adverse events, serious adverse events, suicide … events. … There was also an increased risk of serious adverse events with SSRI use compared with placebo (OR, … The absolute risk of serious adverse events was low, and evidence for specific serious adverse events
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-anxiety-children-adolescents
    October 11, 2022 - , adverse events. … adverse events. … Regarding withdrawal due to adverse events, the pooled RR for CBT trials was 0.39 (95% CI, 0.08 to 1.87 … For both CBT and pharmacotherapy, serious adverse events were rare and the differences between treatment … The evidence suggests that suicide-related harms, serious adverse events, and withdrawal due to adverse
  12. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2001
    April 09, 2001 - What are the adverse effects of screening? … What are the adverse effects of diet or drug treatment? … , statins appear to have few important short- or medium-term (initiation to 5 years) adverse effects. … What are the adverse effects of screening? KQ4. … What are the adverse effects of diet or drug treatment?
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/yw_rbA_nQrCnkaN8X5t56S
    January 01, 2001 - ● What are the adverse effects of diet or drug treatment? … We also included any articles that examined adverse effects and harms of screening or therapy for lipid … What are the adverse effects of screening? KQ4. … What are the adverse effects of diet or drug treatment? … Short- to medium-term adverse effects appear uncommon with statins, but long-term effects are unknown
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-hnLT26c2NHs6thK9yznPF
    July 01, 2002 - Adverse events in 4 randomized controlled trials of breast cancer chemoprevention *Results reported … The number of adverse events, for example, would likely be higher in women with hypertension or other … Adverse events would be lower in subgroups with no predisposition to thromboembolic events and in women … Do chemopreventive agents increase the risk of adverse effects? 5. … The adverse effects of treatment are also well documented.
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/efwy72cuMdhcF2jotkhTzC
    March 29, 2019 - , 78 weeks) reported rates of neuropsychiatric adverse events among participants taking efavirenz; 29.6% … - atric adverse events, 3.3% (95% CI, 2.2%-4.3%) had depression, and 0.6% (95% CI, 0.2%-1.1%) had suicidal … ideation.46 However, an analysis of the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) … Comparative safety and neuropsychiatric adverse events associated with efavirenz use in first-line antiretroviral … Events of Anti-HIV Drugs study.
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/sZN5HHS8w5Sar6bBPabsaB
    June 01, 2008 - �-Blockers: increase in withdrawals secondary to adverse events vs. placebo; NSD in total deaths. … events in the remaining unscreened group (1). … Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized … Systematic review and meta-analysis of clinically relevant adverse events from HMG CoA reductase inhibitor … Statin-related adverse events: a meta-analysis. Clin Ther. 2006;28:26-35. [PMID: 16490577] 131.
  17. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication
    November 13, 2016 - Statins were not associated with increased risk of serious adverse events (RR, 0.99 [95% CI, 0.94 to … Few serious adverse events were reported. … events, serious adverse events, cancer, or elevated liver enzyme levels vs placebo or no statin therapy … events: n = 33,589 Serious adverse events: n = 41,804 Any cancer: n = 55,554 Myalgia: … events (9 trials; RR, 0.95 [95% CI, 0.75-1.21]; I 2 = 86%) Serious adverse events (7 trials;
  18. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - Statins were not associated with increased risk of serious adverse events (RR, 0.99 [95% CI, 0.94 to … Few serious adverse events were reported. … events, serious adverse events, cancer, or elevated liver enzyme levels vs placebo or no statin therapy … events: n = 33,589 Serious adverse events: n = 41,804 Any cancer: n = 55,554 Myalgia: … events (9 trials; RR, 0.95 [95% CI, 0.75-1.21]; I 2 = 86%) Serious adverse events (7 trials;
  19. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/drug-use-illicit-screening
    June 09, 2020 - events such as death and adverse events resulting in hospitalizations or study withdrawal reported at … , with no serious adverse events noted. … events. 125 , 130 , 139 Three studies (n = 638) found no differences in serious adverse events, but … events or study withdrawal due to adverse events vs placebo or pharmacotherapy. … events: 3 trials; RR, 1.54 (95% CI, 0.35 to 8.31); I 2 = 0% Serious adverse events: 3 trials; RR
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
    August 26, 2014 - None of the dietary intervention studies explicitly reported adverse events. … Studies of physical activity interventions reported mostly minor adverse events, and intense physical … events during the trial and 6 specifically reported no adverse events 6 . … Few trials reported details about the adverse events, but most were minor, including musculoskeletal … Serious adverse events were rare.

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