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  1. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/falls-prevention-community-dwelling-older-adults-interventions
    July 21, 2022 - interventions to prevent falls in unselected or increased-risk community-dwelling older adults result in any adverse … Get Up & Go Test, 6-meter timed walk, Functional Reach Test, and Berg Balance Scale) KQ 2: Minor adverseevents that are reported using nonvalidated and nongeneralizable measures Followup Minimum
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4GH3or2_-oQ7ChXfjCB2ux
    March 02, 2020 - and withdrawal due to adverse effects … event was 73.3%.1 Rates of serious adverse events (1.9%) and withdrawal due to ad- verse events (0.4% … reported for older interferon- containing therapies.1 The most common adverse events were fa- tigue, … Five trials reported no withdraw- als due to adverse events; 1 trial reported a serious adverse event … fa- tigue (7 trials), and 3% to 28% for gastrointestinal adverse events (nausea, vomiting, or diarrhea
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/high-blood-pressure-adults-children-adolescents-screening-2003
    April 01, 2003 - As a result, individuals with higher absolute risk for experiencing future adverse cardiovascular events … experience greater absolute benefit from blood pressure reduction than those at lower risk for future adverse … cardiovascular events. … regimen—are common, but serious adverse drug reactions are rare. … Physicians should take adverse effects into consideration when deciding whether to treat and which treatment
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/HhFR4LyVtxMcwmafRH6Ehp
    June 04, 2024 - Multifactorial Interventions Adverse events were sparsely reported for multifactorial interven- tions … Seventeen trials18, 43, 44, 48, 50, 51, 53, 56-58, 61-64, 70, 72, 74 reported any adverse events occurring … during the exercise intervention ses- sions, ranging from 0%18,51,53,63,64 to 58%.56 These adverse events … and 1 trial62 reporting less than 1% serious adverse events related to the exercise intervention (2/ … events as 18% in the intervention group and 12% in the control group; how- ever only 1 adverse event
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/p6k4ooduXN8RQoVGS9H5Sx
    March 01, 2011 - Adverse events were not well reported in trials of behavioral in- terventions, but no serious adverseevents in these trials were uncom- mon; study withdrawals due to adverse events were not reported or … In the NRT trial, no serious adverse events were reported.46 NRT was associated with increased risk … of headache, cough, abnormal dreams, muscle pain, and patch-related adverse events vs placebo (P < .05 … adverse events.
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/DxeDM5ywg2J7SwKmETXfbX
    May 01, 2021 - 13% for men and 6% for women.1 Severe OSA is associated with increased all-cause mortality.2,3 Other adverse … Other adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular … In general, mild OSA is defined as 5 to 15 events per hour, moderate OSA as 16 to 30 events per hour, … or for those with adverse effects associated with positive airway pressure.15,16 Surgical interventions … Adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening-2013
    April 15, 2013 - events; however, many of these events are transient or self-limited, and effective alternatives can … events, including metabolic disturbances associated with an increased risk for cardiovascular events … However, the early treatment group in the HPTN 052 study had ART-related adverse events more frequently … The 2005 USPSTF review included results from the large, ongoing DAD (Data Collection on Adverse Events … Common adverse effects of antiretroviral therapy for HIV disease.
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/o6pGCffkVCx24mNebJGCXg
    January 01, 2013 - Harms included withdrawals due to adverse events, serious adverse events, neutropenia, anemia, psychological … adverse events, influenza-like symptoms, and rash. … There were no differences in risk for withdrawal due to adverse events, serious adverse events, or other … adverse events. … events, with- drawal due to adverse events, neutropenia, depression, fa- tigue, headache, chills/rigors
  9. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
    July 26, 2022 - Twenty-three of the 113 included trials specifically mentioned the occurrence of adverse events or lack … of adverse events (n = 12,452). … Thirteen trials reported adverse events or serious adverse events of any kind, 29-31 , 33 , 41 , 48 , … reported or that no adverse events related to the trial were evident but no additional details were … provided. 33 , 41 , 51 , 62 , 114 , 132 , 136 The other 6 trials found that rates of adverse events
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-TsBkyewVoFpC7htRmzWJa
    September 03, 2019 - Medications to reduce risk of breast cancer are effective for women at increased risk but also cause adverse … However, these medications are also associ- ated with adverse effects,3 and candidates for risk-reducing … All adverse outcomes at all reported follow-up times were considered in an effort to capture potential … short- and long-term adverse effects. … For outcomes of major adverse events, analyses were stratified by active vs posttreatment peri- ods,
  11. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/behavioral-counseling-interventions-promote-healthy-diet-physical-activity-weight-loss-prevent-cardiovascular-disease-adults
    May 18, 2023 - KQ 1: Health outcomes: All-cause and cardiovascular disease mortality Cardiovascular disease events … mellitus Hypertension Dyslipidemia Cardiorespiratory fitness measures KQ 3: Harms: Any adverse … treatment-related harm after initiation of the intervention, including: Any adverse event or serious … adverse event Withdrawals or discontinuation of medication due to adverse effects Unhealthy weight
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/7ZSKduUYHWKe7q_tTY9xbF
    April 01, 2013 - long-term adverse effects. … events, uterine ab- normalities, cataracts, and other adverse effects. … events, than women younger than 50 years. … events and �4% for nonprotocol specified events). … ±SE)‡ Events Reduced or Increased (95% CI), n* RR (95% CI) Trials, n† Placebo Rate (±SE)‡ Events
  13. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-adults-interventions
    September 18, 2018 - events (treatment-related harms and discontinuation of medication because of adverse effects at any … The data on health outcomes (KQ1) and adverse events (KQ3) did not allow for quantitative pooling because … Rates of adverse events were infrequently reported in the behavior-based weight loss and weight loss … higher dropout rates for adverse events in the medication groups than in the placebo groups. … Although rates of serious adverse events were low and generally similar between groups, participants
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/yzXkWEQV3pn95yd_pmXZXk
    December 15, 2020 - receiving placebo or no treatment, and that some adverse events resolve after discontinuing therapy. … Pooled analyses found no sig- nificant differences in the risk of serious adverse events (4 trials; RR … , 0.92 [95% CI, 0.45-1.85]), any adverse event (5 trials; RR, 1.01 [95% CI, 0.90-1.11]), renal adverseevents (3 trials; RR, 1.27 [95% CI, 0.31-3.55]), or study withdrawal due to adverse events (3 trials … No significant differences in risk of serious adverse events or withdrawal due to adverse events were
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/KFZpoMBYuoo8TRW6nhRev8
    October 23, 2023 - health outcomes Adverse events Event-driven vs daily oral PrEPb ADAPT/HPTN 067 Bekker et al,12 2018 … Clinical health outcomes Adverse events Long-acting injectable cabotegravir vs daily oral TDF/FTC … All adverse events were grade 1 except in 1 patient with grade 2 symptoms. … events or grade 3 or higher adverse events (Table 2; eTables 1-4 in the Supplement).6,7 There were also … adverse events, or STIs.
  16. www.uspreventiveservicestaskforce.org/uspstf/reconsidering-approach-prevention-recommendations-older-adults-figure-2
    December 01, 2010 - interventions to reduce falls and fall-related outcomes Figure 2 is an analytic framework that depicts the events … Risk Evaluation, Intervention, Intermediate Outcomes, Health Outcomes, Other Positive Outcomes, and Adverse … Minor adverse outcomes associated with specific interventions include: increased fall-related outpatient … KQ3: What are the adverse effects associated with interventions to reduce falls?
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/_2-KL_eHkuBhbGrzcAHsB-
    June 01, 2022 - or stress, bullying, maltreatment, adverse life events, and a difficult relationship with parents. … Adverse childhood experiences in- fluence the likelihood of experiencing mental health conditions such … events and serious adverse events compared with placebo; the dif- ferences were not statistically significant … , likely because of a small number of events due to poor reporting. … There were no significant differences in adverse events reported.1,2 Response to Public Comment A draft
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary34/lipid-disorders-in-children-screening-2007
    July 15, 2007 - of screening for dyslipidemia in identifying children/adolescents at increased risk of CHD-related events … the incidence of adult dyslipidemia, and delaying the onset and reducing the incidence of CHD-related events … Information about adverse events was reported in 15 studies of statins, 18 , 19 , 165 , 169 , 172 , 173 … reducing incidence of adult dyslipidemia or delaying the onset and reducing the risk of CHD-related events … There are no trials with long-term follow-up for adult lipid outcomes or CHD-related events.
  19. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-depression-suicide-risk-adults
    June 20, 2023 - There was also evidence of an increased risk of serious adverse events with use of selective serotonin … events appears to be relatively low, however, and evidence for specific serious adverse events was very … The study of lithium found a higher rate of nonserious adverse events (75.7% with lithium, 69.0% with … , 34.1% with placebo; P value not reported) but no difference in withdrawals due to adverse eventsevents with all agents examined and a higher risk of serious adverse events with SSRI use (OR, 1.39
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/hWzpnYXDpQzUr8U_5xY6qS
    January 01, 2003 - As a result, individuals with higher absolute risk for experiencing future adverse cardiovascular events … cardiovascular events. … Potential adverse effects of drugs—some sufficiently bothersome to interfere with adherence to the medica … - tion regimen—are common, but serious adverse drug reactions are rare. … Physicians should take adverse ef- fects into consideration when deciding whether to treat and which

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