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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
August 22, 2023 - events (7.5% vs 6.9%) or study drug discontinuation due to adverse events (1.5% vs 1.9%). … events or grade 3 or higher adverse events ( Table 2 ; eTables 1-4 in the JAMA Supplement). 6 , 7 … liver-related adverse events, or STIs. … events, discontinuation due to adverse events, or any adverse event: 1 new RCT (n = 5387)
Serious … adverse events: 7% vs 7% Discontinuation due to adverse events: 1% vs 2% Any adverse event: 94% vs 94%
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-c-screening
March 02, 2020 - events (1.9%) and withdrawal due to adverse events (0.4%). … of therapy). 12-55
Adverse Events in Comparative Trials. … due to adverse events, headache, or fatigue. … Rates of other adverse events were highly variable. … events
There was 1 serious adverse event (grade 3 joint injury) in 1 study
The rate of any adverse
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nonpregnant-adolescents-and-adults1/human-immunodeficiency-virus-hiv-infection-screening
June 11, 2019 - use based on 4 cohort studies, including the Data Collection on Adverse Events of Anti-HIV Drugs (D: … Hepatic and Renal Adverse Events
Analysis of data from the D:A:D study (n = 45,544) found long-term … Some new evidence also indicates that long-term hepatic, renal, and bone (fracture) adverse events are … Mocroft A, Lundgren JD, Ross M, et al; Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study … Comparative safety and neuropsychiatric adverse events associated with efavirenz use in first-line antiretroviral
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/q_zxLD9JZFGoSPCrEHNk2g
June 11, 2019 - events with abacavir use based on 4 cohort stud-
ies, including the Data Collection on Adverse Events … Hepatic and Renal Adverse Events
Analysis of data from the D:A:D study (n = 45 544) found long-
term … Some new evidence also indicates that
long-term hepatic, renal, and bone (fracture) adverse events are … Mocroft A, Lundgren JD, Ross M, et al; Data
Collection on Adverse Events of Anti-HIV Drugs
(D:A:D) Study … Comparative safety and neuropsychiatric adverse
events associated with efavirenz use in first-line
antiretroviral
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan21/chlamydia-and-gonorrhea-screening-september-2014
June 15, 2013 - Analytic Framework (Text Description)
This analytic framework is a diagram that depicts the events … During the screening, they may experience adverse events, they may be diagnosed with a gonococcal or … Analytic Framework (Text Description)
This analytic framework is a diagram that depicts the events … During the screening, they may experience adverse events, they may be diagnosed with a gonococcal or … chlamydia infection, and they may go through treatment, which could lead to adverse effects.
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/chronic-kidney-disease-screening
January 19, 2023 - change in albuminuria)
KQs 1, 4, 6: Progression to stage 4 or stage 4/5 CKD
KQs 2, 5, 8:
Any adverse … events
Serious adverse events
Specific adverse events
Renal adverse events
KQs 3, 3a:
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis-june-2019
June 11, 2019 - PrEP was associated with an increased risk of renal adverse events (12 trials; RR, 1.43 [95% CI, 1.18 … -1.75]; I 2 = 0%; ARD, 0.56% [95% CI, 0.09%-1.04%]) and gastrointestinal adverse events (12 trials; … RR, 1.63 [95% CI, 1.26-2.11]; I 2 = 43%; ARD, 1.95% [95% CI, 0.48%-3.43%]); most adverse events were … However, for both of these adverse events there was only 1 trial of tenofovir disoproxil fumarate. … events
Good
Most trials did not report withdrawals resulting from adverse events Composite outcome
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/bQNXFv9Q5uaAQvWH6B7VWV
June 11, 2019 - PrEP was associated with an increased risk of
renal adverse events (12 trials; RR, 1.43 [95% CI, 1.18 … -1.75]; I2 = 0%; ARD, 0.56% [95% CI,
0.09%-1.04%]) and gastrointestinal adverse events (12 trials; RR … , 1.63 [95% CI, 1.26-2.11];
I2 = 43%; ARD, 1.95% [95% CI, 0.48%-3.43%]); most adverse events were mild … PrEP was associated with increased risk vs placebo of renal
adverse events (12 trials [n = 18 170]; … events
Good Most trials did not report
withdrawals resulting from
adverse events Composite
outcome,
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-b-virus-infection-screening
December 15, 2020 - events (7 trials, n = 3136), 35 , 38 , 40 , 41 , 43 , 82 withdrawal due to adverse events (7 trials … events (RR, 2.41 [95% CI, 0.86 to 6.74]), withdrawal due to adverse events (RR, 4.01 [95% CI, 0.86 to … events or experiencing any adverse event vs placebo. … adverse events vs lamivudine, consistent with known adverse effects of interferon-based therapies. … to adverse events: 3 trials, n = 496; RR, 4.44 (95% CI, 0.95-20.77); I 2 =0% 22 , 24 , 27 Any adverse
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions-september-2015
September 21, 2015 - The USPSTF also evaluated adverse events reported at any time point. … Adverse events related to other forms of behavioral interventions were not reported. … 1.24 [CI, 0.85 to 1.81]) or major cardiovascular adverse events (RR, 1.44 [CI, 0.73 to 2.83]). … events related to product use or any difference in the frequency of adverse events. 8 One study 30 … Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan88/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions-september-2015
February 18, 2014 - individuals with mental health conditions, lead to improved health outcomes, tobacco abstinence, or adverse … events.
… What adverse events are associated with tobacco cessation interventions? … events
Serious treatment-related harms at any time point after the intervention began … events associated with medications
Paradoxical increase in tobacco use
Demoralization
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
January 19, 2021 - Cardiac adverse events and other serious adverse events did not differ by type of NRT. 63
The USPSTF … events (RR, 1.30 [95% CI, 1.00-1.69]; 33 trials; n = 9631), 83 cardiovascular adverse events (RR, 1.03 … events or cardiovascular severe adverse events was found. 13 Additionally, no statistically significant … Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. … be associated with an increased risk of general severe adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-kidney-disease-screening
July 13, 2023 - change in albuminuria)
KQs 1, 4, 6: Progression to stage 4 or stage 4/5 CKD
KQs 2, 5, 8:
Any adverse … events
Serious adverse events
Specific adverse events
Renal adverse events
KQs 3, 3a:
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan54/colorectal-cancer-screening-june-2016
April 17, 2014 - b) Do adverse effects vary by important subpopulations (e.g., by age)? … events requiring unexpected or unwanted medical attention and/or resulting in death (e.g., requiring … including but not limited to perforation, major bleeding, severe abdominal symptoms, and cardiovascular events … ; extra-colonic findings and subsequent diagnostic workup and adverse events from diagnostic testing … events defined as those not necessarily needing or resulting in medical attention (e.g., patient dissatisfaction
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
January 19, 2021 - None of the drugs were associated with serious adverse events. … events, including major cardiovascular adverse events or serious neuropsychiatric events, as compared … events
NRT was associated with a higher rate of any cardiovascular adverse events, largely driven … events, particularly cardiovascular- or neuropsychiatric-specific adverse events
Adverse events typically … events
NA
Very few reviews assessed adverse events related to behavioral interventions
Moderate
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/KSYrhQuAswGjTww_4sDFGZ
December 01, 2007 - events are
uncommon. … Serious adverse effects were uncommon, and 2 of the 3
reported events were probably not related to the … due to adverse events
was 11%. … Other adverse events were hyperkalemia
in 2 eplerenone recipients and 1 amlodipine recipient, and
hypokalemia … events are uncommon.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary15/blood-pressure-in-adults-hypertension-screening-2007
October 15, 2007 - events are uncommon. … Serious adverse effects were uncommon, and 2 of the 3 reported events were probably not related to the … due to adverse events was 11%. … Other adverse events were hyperkalemia in 2 eplerenone recipients and 1 amlodipine recipient, and hypokalemia … events are uncommon.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/xUc_vXf7323faUQY7SePhT
January 01, 2002 - and its
likelihood of causing adverse effects. … the participants had definite or suspected
vascular disease.12,13
From our search for articles on adverse … Adverse Effects of Aspirin Therapy
Hemorrhagic stroke. … effect of aspirin, a reduction in nonfatal
myocardial infarction, cannot be directly equated to
an adverse … Adverse effects of low-dose
aspirin in a healthy elderly population.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cardiovascular-disease-screening-using-nontraditional-risk-assessment
September 03, 2015 - factor assessment or treatment based on nontraditional risk factor assessment are associated with any adverse … events (KQ3 and KQ5). … risk factors—followed by treatment specific to risk level—lead to reduced incidence of cardiovascular events … c-statistic), and calibration (e.g., agreement between observed and predicted risks)
KQs 3, 5: Serious adverse … events from risk factor assessment or aggressive risk factor modification resulting in unexpected or
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/T6Tquunynv3tWM65BFash2
October 01, 2015 - The USPSTF also evaluated adverse events
reported at any time point. … Adverse events related to other forms of behavioral in-
terventions were not reported. … events (RR, 1.24 [CI, 0.85 to 1.81]) or
major cardiovascular adverse events (RR, 1.44 [CI, 0.73
to 2.83 … events related to product use or any difference
in the frequency of adverse events (8). … Adverse events
associated with nicotine replacement therapy (NRT) for smoking ces-
sation.