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81. Evidence Summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2022 Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
    January 01, 2022 - There was no increase in risk of serious adverse events or withdrawal due to adverse events. … Some nonopioid treatments had frequent overall adverse events and some less frequent yet serious adverse … effects, while nonpharmacological treatments typically reported few adverse events.10 Cannabinoids … Other prioritized adverse events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … The evidence on adverse events with cannabis-related products is much less robust than the evidence

82. Comparative Effectiveness of First and Second Generation Antipsychotics in the Adult Population | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research-protocol
    December 01, 2010 - Outcomes: Disorder-specific and -nonspecific adverse events: Overall adverse events. … Specific adverse events: Major: mortality, cerebrovascular disease-related events, development of diabetes … Study withdrawals/time to withdrawal because of adverse events. … events include overall events, specific events, study withdrawals because of adverse events, time to … withdrawal because of adverse events, and persistence and reversibility of adverse events.

83. Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), and Direct Renin Inhibitors for Treating Essential Hypertension – An Update of the 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/ace-inhibitor-arb-update/research-protocol
    May 07, 2010 - event rates, overall adverse event rates, and withdrawals due to adverse events, withdrawal rates, switch … rates) Specific adverse events (including, but not limited to, weight gain, impaired renal function … Also, adverse events (including, but not limited to, weight gain, impaired renal function, angioedema … events, withdrawals due to adverse events, serious adverse events reported, withdrawal rates, switch … rates) Specific adverse events , including but not limited to weight gain, impaired renal function

84. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
    January 01, 2017 - events (frequency of any adverse events reported in trials) • Withdrawals due to adverse events, time … • Significant (major) adverse events Key Question 2: • Overall adverse events (frequency of any adverse … events reported int rials) • Withdrawals due to adverse events, time to withdrawal due to adverse events … events, and withdrawal from treatment due to adverse events. … events and withdrawal due to adverse events.

85. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
    September 01, 2011 - Adverse events 22 Low 1 fair trial: no significant differences in ECT + rTMS specific adverse events … VNS vs. sham Adverse events 235 Low 1 fair trial: Some differences in specific adverse events reported … Safety, Adverse Events, and Adherence (KQ 4) Direct evidence. … Specific adverse events. … More careful and consistent assessment of adverse events is required.

86. Draft Report: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/draft-report-plant-based-treatment.pdf
    March 01, 2021 - events (dizziness, sedation, nausea) and study withdrawal due to adverse events with cannabis products … events, serious adverse events, and sedation, and a large increased risk of dizziness compared with … events and dizziness, and moderate increased risk of serious adverse events. … No adverse events were reported. … Similarly, adverse events such as cannabis use disorder, cognitive deficits, and serious adverse events

87. Pbt-Lsr-Draft-Report (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbt-lsr-draft-report.pdf
    February 04, 2022 - There was no increase in risk of serious adverse events or withdrawal due to adverse events. … events and dizziness, and moderate increased risk of serious adverse events. … Adverse events were reported in all the trials. … No adverse events were reported. … Similarly, adverse events such as CUD, cognitive deficits, and serious adverse events may take time

88. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - b: Are there any differences in safety, adverse events, or adherence between immediate release and … Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. IV. … events Withdrawals because of adverse events Discontinuation rates because of adverse events … Serious adverse events Specific adverse events or withdrawals because of specific adverse events

89. Breast-Biopsy-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - • What factors associated with the patient and her breast abnormality influence the adverse events of … Events and Additional Surgeries After Biopsy In general, adverse events were reported inconsistently … Core needle biopsy was only infrequently associated with serious adverse events. … adverse events) compared to core needle biopsy. … Our assessment of the strength of evidence for adverse events is summarized in Table H.

90. Update Topic Brief CER 27 NSD FINAL_SJ final (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
    January 17, 2014 - mellitus, what is the comparative safety of the following treatment options in terms of the following adverse … events and side effects? … addition to updating information on the potential benefits of available treatments, conclusions regarding adverse … events should also be updated. … There have been a number of potential adverse events associated with rosiglitazone (e.g. increased

91. Methods-Guide-Chapter-Prioritization-And-Selection-Of-Harms-For-Inclusion-In-Systematic-Reviews (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
    February 01, 2018 - events and may include common adverse events or other adverse events important to clinicians and patients … events,” rather than composite harms that include less serious events (e.g., “any adverse event”), … “serious adverse events” or “withdrawal due to adverse events,” particularly when evaluating head-to-head … events or “withdrawal due to adverse events”), given the composite nature of these outcomes, as it … • Collect some information on serious adverse events and total number of events.

92. Comparative Effectiveness and Safety: Emerging Methods - Part I | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/safety-emerging-methods/executive
    September 25, 2007 - Developing Indicators of Inpatient Adverse Drug Events Through Nonlinear Analysis Using Administrative … Developing Indicators of Inpatient Adverse Drug Events Through Non-Linear Analysis Using Administrative … Real-Time Vaccine Safety Surveillance for the Early Detection of Adverse Events Tracy A. … Real-Time Vaccine Safety Surveillance for the Early Detection of Adverse Events. … Evaluation and Overview of the National Electronic Injury Surveillance System-Cooperative Adverse Drug

93. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
    April 01, 2020 - Harms and Adverse Events a. … events, serious adverse events, somnolence, nausea, vomiting, constipation, dizziness, headache, and … adverse events, with no difference in risk of serious adverse events (SOE: low) … Rates of adverse events of long-acting opioids in a state medicaid program. … Opioid medication discontinuation and risk of adverse opioid-related health care events.

94. Cancer-Anemia-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
    April 01, 2013 - Transfusion carries a very low risk of infection and other adverse events, including transfusion reactions … (For example, adverse events that could be definitively attributed to transfusions were not reported … Thromboembolic Events ESA treatment increased the risk of thromboembolic events (overall strength of … There were fewer thromboembolic and on-study mortality adverse events when ESA treatment was delayed … Whether there are subgroups at higher and lower risk of adverse events and mortality is unclear.

95. Community Pharmacy/Call Center Assessment of Medication Effectiveness & Safety | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/medicine-safety-call-center/research
    December 02, 2009 - Abstract Adverse drug events impose a large cost on the society in terms of lives and healthcare costs … In this paper, we propose an information technology architecture for enabling the monitoring of adverse … drug events in an outpatient setting as a part of the post marketing surveillance program. … on previous studies analyzing the involvement of community pharmacies in identifying and reporting adverse … drug events.

96. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/antidepressants-update/research-protocol
    July 13, 2011 - Are there any differences in safety, adverse events, or adherence between immediate release and extended … Also, adverse events may occur at any point after the treatment is received. … Also, adverse events may occur at any point after the treatment is received. Methods A. … events Withdrawals because of adverse events Discontinuation rates because of adverse events Serious … adverse events Specific adverse events or withdrawals because of specific adverse events, including

97. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
    September 23, 2016 - Harms Outcomes: KQ 1: § Overall adverse events (frequency of any adverse events reported in trials … events (frequency of any adverse events reported in trials) § Withdrawals due to adverse events, … events (frequency of any adverse events reported in trials) • Withdrawals due to adverse events, time … ) • Significant (major) adverse events KQ 2: • Overall adverse events (frequency of any adverse events … reported in trials) • Withdrawals due to adverse events, time to withdrawal due to adverse events

98. Cer-242-Radiation-Therapy-Brain-Metastases-Evidence-Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
    June 01, 2021 - • We did not detect consistent differences in serious adverse events, number of reported adverse … events, radiation necrosis, headaches, fatigue and seizures across interventions. … events, adverse events, radiation necrosis, headaches, fatigue, seizure, vomiting. … Adverse Events We found no difference in serious adverse events when comparing WBRT plus SRS with … Events Effects of Patient Characteristics Strengths and Limitations Implications and Conclusions

99. CER 220 Evidence Summary: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-220-analgesics-acute-pain-summary.pdf
    September 01, 2019 - The intranasal route was common in studies reporting adverse events for the comparison of opioids versus … Opioids may cause fewer adverse events than ketamine, primarily administered IN. … Opioids may cause more adverse events than NSAIDs, administered primarily IV. … evidence suggests that opioids may cause fewer total adverse events than ketamine. … In contrast to the comparison of opioids with ketamine, opioids may cause more adverse events than

100. CER 220 Evidence Summary: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
     September 01, 2019 - The intranasal route was common in studies reporting adverse events for the comparison of opioids versus … Opioids may cause fewer adverse events than ketamine, primarily administered IN. … Opioids may cause more adverse events than NSAIDs, administered primarily IV. … evidence suggests that opioids may cause fewer total adverse events than ketamine. … In contrast to the comparison of opioids with ketamine, opioids may cause more adverse events than