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Showing results for "adverse events".
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  1. TND-0775-150722 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
    May 12, 2015 - . § Common adverse effects of many antipsychotics used for schizophrenia include: weight gain, diabetes … disorder, with a focus on core illness symptoms, functional outcomes, health care system utilization, and adverseevents.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
    April 01, 2010 - events Questions 1–3: • Timing o At the end of the treatment o Short-term outcomes (2–6 weeks … We define harms as a totality of all possible adverse consequences of an intervention.34 We will analyze … For categorical variables we will abstract a number of events among treatment groups to calculate rates … We will calculate differences in relative risk and absolute risk from the abstracted events by using … The number of avoided or excess events (respectively) per population of 1000 is the difference between
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
    February 10, 2010 - billion.5 The aim of asthma management is to achieve and maintain control of the disease with as few adverse … Question 3 What is the nature and frequency of serious adverse effects of treatment with breathing … Events: • Increased asthma symptoms or acute asthma exacerbations • Adverse reactions to therapies … The figure also depicts the possibility of adverse events occurring at any time after treatment begins … events (KQ 1) Use of breathing exercise or retraining (KQ 2) http://www.effectivehealthcare.ahrq.gov
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - Although six studies reported low rates (0 to 1.2%) of death or serious adverse events among patients … to treatment for opioid use disorder and risk of future overdose episodes, in addition to serious adverseevents. … might be associated with a low rate of serious harms, but patients were probably at low risk for such eventsAdverse events after naloxone treatment of episodes of suspected acute opioid overdose.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_executive.pdf
    August 01, 2016 - , medication use, and adverse events. … Procedural adverse events were rare and no medication-related adverse events were reported. … Clinically important adverse events related to PTRAS are rare; however, studies generally failed to … report medication-related adverse events. … Data on adverse events were, overall, sparse, particularly for medical therapy.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
    September 22, 2014 - drug events related to antibiotics. … Adverse!effects! of!the!strategy! … confounding factors; and whether the duration of follow-up was reasonable to capture investigated eventsevents) KQ3: Other clinical outcomes (health care utilization, hospitalization, patient satisfaction … events) KQ4: Other clinical outcomes (health care utilization, patient satisfaction) KQ 5: Intermediate
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
    January 01, 2011 - events, such as increased cardiovascular morbidity and mortality. 12,14,15 For this reason, accurate … What are the adverse effects or harms associated with testing using newer and/or older markers of iron … What are the adverse effects or harms associated with the treatments guided by tests of iron status … , adverse events secondary to venipuncture, effects of iron overload with iron treatments, cardiovascular … events related to lab testing Adverse events related to management strategies KQ1 KQ
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
    September 02, 2016 - arkers 24. or/1-23 n-3 25. exp cardiovascular diseases/ C ardiovascular diseases, risk factors, adverseevents 26. atherosclero$.mp. … all outcomes) • Randomized cross-over (XO) studies (blood pressure and lipids, adverse events) • Nonrandomized … comparative studies, prospective or retrospective longitudinal (clinical outcomes, adverse events): … /nRCS: no minimum; Longitudinal single group N≥100 o BP/Lipids (RCT): N≥x (no minimum for now) o Adverse
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
    October 17, 2012 - Settings Clinical settings Clinical settings General and clinical settings Clinical settings AdverseAdverse events (AE) may occur at any point after the meditation program. … We will model rare adverse events (<1%) using the Peto Odds ratio approach which has the best confidence … We will model rare adverse events (<1%) using the Peto Odds ratio approach which has the best confidence … Adverse events (AE) may occur at any point after the meditation program.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-child-interventions_research-protocol.pdf
    March 26, 2012 - with a physical illness, 11%; serious accident, 11.6%; natural disaster, 11.1%; fire, 5.9%).1 The Adverse … of childhood trauma exposure in a large adult population.4 In this population, 65 percent recalled adverse … The criteria for DTD include exposure to multiple or prolonged adverse events and experiences of affective … Traumatic events and posttraumatic stress in childhood. … household dysfunction, and the risk of attempted suicide throughout the life span: findings from the Adverse
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
    August 01, 2012 - consequences of an intervention, including adverse events (Figure A).14 Key Questions We have synthesized … events in ASD without being limited to a specific age range. … events be listed for a drug, rather than just those for a particular indication. … events may be associated with medication use in adolescence. … The effects of a rotating classroom schedule on classroom crisis events in a school for autism.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
    December 31, 2017 - are more effective for victims of particular types of trauma or to determine comparative risks of adverse … KQ 4: What adverse events (AEs) are associated with treatments for adults diagnosed with PTSD? … AE = adverse events; CBT = cognitive behavioral therapy; DSM = Diagnostic and Statistical Manual; EFT … Impact of Events Scale - Revised (IES-R). … caused by traumatic events
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
    January 30, 2012 - review, as well as demographic and other data needed for determining outcomes (intermediate, final, and adverseevents outcomes). … The safety outcomes will be framed to help identify adverse events, including those from drug therapies … study design; patient characteristics; clinical settings; interventions; and intermediate, final, and adverse … , intervention group rates of events, or both.
  14. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
    September 01, 2011 - Of these, at least three maternal deaths and three cardiovascular adverse events were clearly reported … However, given the small number of events and limited sample size (n=42), the RCT was underpowered and … events—the rarer the adverse event, the stronger is the effect size, and the magnitude of effect size … is an important criterion that increases our confidence in an estimate.9 However, adverse events such … events in the absence of terbutaline therapy due to other reasons.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
    December 09, 2009 - events, or adherence? … Adverse effects of interest include but are not limited to: amnesia, memory loss, headaches, post-operative … : ECT, rTMS, VNS, demonstrated effective psychotherapy • Outcomes for each question • Safety • AdverseEvents • Adherence • Timing: Acute phase and continuation phase treatments • Settings: Mental … KQ4 focuses on safety issues (adverse effects, adherence) with each of the interventions.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
    September 01, 2011 - Specifically, the reported adverse event experience with TMS is now very well established in the two … events observed in TMS George, et al, (2010) was included during the update search phase post submission … (2000) The effects of electroconvulsive therapy in memory of autobiographical and public events. … events, and therefore lacks the toxicities of more complex antidepressant pharmacotherapies or the … events responded better to the form of CBT tested than to any drug intervention.
  17. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
    April 01, 2007 - Adverse Event Detection, Processing, and Reporting The U.S. … Food and Drug Administration defines an adverse event (AE) as any untoward medical occurrence in a patient … reporting for all marketed products is dependent on the principle of “becoming aware,” collection of adverse … • The process for identifying serious events is described and a plan is created for reporting, as … • For safety studies, personnel are appropriately trained to ask about complaints or adverse events
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
    January 01, 2012 - care or other interventions without SMBP in its effect on relevant clinical outcomes (cardiovascular events … , mortality, patient satisfaction, quality of life, and adverse events related to antihypertensive … Note: AE = adverse event; BP = blood pressure; CVD = cardiovascular disease; KQ = Key Question; LVH = … , mortality, patient satisfaction, quality of life, and adverse events related to antihypertensive … One quality C trial found no difference in adverse drug reactions across four groups with different
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
    January 01, 2014 - What are the adverse effects associated with each diagnostic test (including pain, infection at the … events: immediate • Settings: o Primary care (outpatient) or acute care setting, preferentially … events (including adverse patient experiences such as pain or infection at the aspiration site, effects … events will be included for key question 2, in anticipation that few studies will address the question … of adverse outcomes or patient satisfaction with diagnostic procedures.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
    December 01, 2011 - It seems unusual to present a reduced incidence of an adverse effect with an NNT. … Peer Reviewer #5 Results KQ4 Page 123 or page 108, line 44 Adverse Events and Discontinuation Rates: … events such as suicidality, seizures, cardiovascular adverse events, serotonin syndrome, hyponatremia … This is reflected in the differential adverse effect profile of somnolence with mirtazapine. … We included this study in KQ4 on adverse events Peer Reviewer #3 Introduction Table 5.

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