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Showing results for "adverse events".
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401. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - • Acute adverse events (AEs) were significantly fewer with PBI compared with WBI, with no apparent … This highlights the need to investigate outcomes of PBI among patients with adverse risk factors. … These advancements result in improved dose homogeneity that may lower the risk for adverse events. … PBI is associated with fewer acute adverse effects, but the risk of IBR among patients treated with … PBI who have adverse clinical or pathologic features is unclear.

402. Pharmacotherapy for Adults with Alcohol-Use Disorders in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
     September 01, 2017 - Adverse effects of intervention(s): withdrawals due to adverse events, nausea/vomiting, diarrhea, anorexia … Naltrexone One study 24 (n=128) reported no serious adverse events, but an increase in sleepiness … Baclofen There were no serious adverse events related to baclofen in two studies: one RCT (n=56), 23 … The majority of serious adverse events in the placebo group (88%) and the nalmefene group (76%) were … They reported mental slowing, a reduction in verbal fluency and working memory as adverse events among

403. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
     April 01, 2020 - in frequency of intervention-related adverse events or withdrawals. … Table 64 in the full report summarizes reported adverse events for each intervention. … No serious intervention-related adverse events leading to death or disability or requiring intensive … Evidence was low or insufficient for other adverse events. … Acupuncture-related adverse events: a systematic review of the Chinese literature.

404. Comparative Effectiveness of Treatment for Hepatitis C in Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hepatitis-c/research-protocol
     November 30, 2011 - In addition, psychiatric, gastrointestinal, dermatological, and hematologic adverse effects underlie … of life, hepatic cirrhosis, hepatocellular carcinoma, and liver transplants Transmission of HCV Adverse … effects of intervention(s) Harms from antiviral treatment, including withdrawals due to adverse events … , serious adverse events such as severe neutropenia, psychological adverse events, flu-like symptoms, … and hematological adverse events Timing and Setting: No minimum timing and all settings included

405. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Withdrawals due to adverse events were below 10% in all treatment groups. … Withdrawals due to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were similar. … Headache, nausea, and dizziness were the most common lorcaserin-related adverse events. U.S. … Common adverse events were headache, back pain, nasopharyngitis, and nausea.

406. Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis – An Update of the 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/osteoporosis-bone-fracture/research-protocol
     May 14, 2010 - events will be analyzed for KQ4. … Outcomes: Any reported harms/adverse events (AEs) that can be directly associated with use of an agent … KQ4 assesses the evidence for adverse effects of treatment. … Events.9 Then, a verbatim account of the AE will be recorded on the form. … Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0.

407. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
     July 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the potential benefits and adverse … Noninvasive nonsurgical fecal incontinence treatments had few minor adverse effects. … Longer term information on benefits and adverse effects would better inform clinical decisions for … Substantial and life- altering adverse events sometimes occur after surgery for fecal incontinence, … and these events were underidentified in randomized controlled trials (RCTs) alone. �� Addressing the

408. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
     January 01, 2019 - events, side effects of interventions (any time frame) o Hospitalization comparison:  Hospital-based … infections and other harms o Antibiotics comparisons:  Side effects/adverse events attributable … events related to procedures, including bleeding and catheter infections  Need for second procedures … o N≥30/arm* • Single group studies o Only for adverse events o N>100† • Longitudinal (Exclude: … events, and side effects of colonoscopy (e.g. perforation, bleeding) Modifiers/Subgroups of interest

409. Bladder-Cancer-Muscle-Invasive Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-muscle-invasive_executive.pdf
     June 01, 2015 - events; withdrawals due to adverse events; and sources of funding. … Although cisplatin is nephrotoxic, renal adverse events were not well reported.28 No study compared … radical cystectomy: adverse events Insufficient There was insufficient evidence from 4 studies of … with grade 3 or 4 hematological adverse events. … Adjuvant chemotherapy vs. no adjuvant chemotherapy: adverse events Insufficient Harms were poorly

410. Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non–Small-Cell Lung Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/lung-cancer-nonsurgical-therapies/research
     June 12, 2013 - sought studies reporting overall survival, cancer-specific survival, local control, symptom relief, adverse … events, and quality of life among our populations of interest. … Outcomes of therapy for all Key Questions included overall survival, adverse effects, and quality of

411. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
     November 03, 2011 - o Treatment discontinuation due to adverse effects. … For categorical variables we will abstract the number of events among treatment groups to calculate … percent CI, we will calculate the relative risk and absolute risk difference from the abstracted events … Time course of adverse events most commonly associated with topiramate for migraine prevention. … A systematic review of adverse events in placebo groups of anti-migraine clinical trials.

412. Migraine-Adults-Executive-130408 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
     April 01, 2013 - For categorical variables, we abstracted the number of events among treatment groups to calculate rates … We used default software continuity coefficients for 0 events and intention to treat as recommended … The number of avoided or excessive events per population of 1,000 is the difference between the two … Time course of adverse events most commonly associated with topiramate for migraine prevention. … A systematic review of adverse events in placebo groups of anti-migraine clinical trials.

413. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
     January 09, 2020 - In addition to effectiveness, decisionmakers need information on potential adverse risks, and special … Pain, function, pain relief satisfaction and quality of life, harms/adverse events (including withdrawal … events KQ 3: Non-invasive non-pharm Therapy: Pain, function, pain relief satisfaction, quality of … life and quality of life, harms, adverse events None Timing At the following intervals: < 1 day … events in patients with migraine.

414. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
     March 01, 2018 - Comparison of the sample size, primary outcome, and withdrawals due to adverse events reported in the … ClinicalTrials.gov began to mandate reporting of adverse events in September 2009 as serious adverse … events and non-serious adverse events. … We compared the total adverse events reported in ClinicalTrials.gov with the total reported in the … CT.gov reported more adverse events.

415. A Multicenter, Observational Cohort Study to Assess the Cardiovascular Risks of Medications Prescribed for Attention Deficit Hyperactivity Disorder | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/adhd-medicines-risks/abstract
     January 01, 2005 - Food and Drug Administration review of its Adverse Event Reporting System (AERS) for cases of sudden … identifying important cardiovascular outcomes, and assessing the overall risk of serious cardiovascular events … ADHD drugs and serious cardiovascular events in children and young adults. N Engl J Med 2011 Nov 1.

416. Treatments for Seasonal Allergic Rhinitis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/allergy-seasonal/research-protocol
     March 08, 2012 - events. … events resulting from systemic absorption, such as impaired bone growth, reduced height, suppression … events in SAR research. … Additionally, systematic reviews and meta-analyses that specifically assess adverse events associated … events, and results.

417. Kidney-Disease-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
     October 01, 2012 - events that should be followed up. … events data from different studies, adverse events reported generally were consistent with known … Relation between kidney function, proteinuria, and adverse outcomes. … Raloxifene was associated with significantly fewer kidney-related adverse events compared with placebo … events data from different studies, adverse events reported generally were consistent with known potential

418. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
     March 01, 2010 - The adverse events include altered glucose, diabetes mellitus, lymphoid overgrowth, and malignancy. … KQ 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of treatment … Key question 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted … Key question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of

419. Quantitative Synthesis: Chapter 2. Presenting Different Effects for Different Data Types (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
     February 01, 2018 - Example binary data for effect size computation Treatment Events in Treatment Group Treatment n … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the Presence of Treatment-Induced Adverse … Events. … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the Presence of Treatment-Induced Adverse … Events.

420. Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin - Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
     December 01, 2017 - • Serious adverse events, events leading to treatment discontinuation, and treatment site infections … Adverse Events, All BCC Lesions In Table B drugs were most likely to have adverse events leading to … Events Leading to Discontinuation (95% CI) Serious Adverse Events (95% CI) Adverse Events: … Adverse Events, All SCCIS Lesions In Table C the highest mean frequency of adverse events leading to … Adverse events were inconsistently reported.