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Showing results for "adverse events".
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401. Comparative Effectiveness of Treatment for Hepatitis C in Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hepatitis-c/research-protocol
     November 30, 2011 - In addition, psychiatric, gastrointestinal, dermatological, and hematologic adverse effects underlie … of life, hepatic cirrhosis, hepatocellular carcinoma, and liver transplants Transmission of HCV Adverse … effects of intervention(s) Harms from antiviral treatment, including withdrawals due to adverse events … , serious adverse events such as severe neutropenia, psychological adverse events, flu-like symptoms, … and hematological adverse events Timing and Setting: No minimum timing and all settings included

402. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
     July 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the potential benefits and adverse … Noninvasive nonsurgical fecal incontinence treatments had few minor adverse effects. … Longer term information on benefits and adverse effects would better inform clinical decisions for … Substantial and life- altering adverse events sometimes occur after surgery for fecal incontinence, … and these events were underidentified in randomized controlled trials (RCTs) alone. �� Addressing the

403. Migraine-Adults-Executive-130408 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
     April 01, 2013 - For categorical variables, we abstracted the number of events among treatment groups to calculate rates … We used default software continuity coefficients for 0 events and intention to treat as recommended … The number of avoided or excessive events per population of 1,000 is the difference between the two … Time course of adverse events most commonly associated with topiramate for migraine prevention. … A systematic review of adverse events in placebo groups of anti-migraine clinical trials.

404. A Multicenter, Observational Cohort Study to Assess the Cardiovascular Risks of Medications Prescribed for Attention Deficit Hyperactivity Disorder | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/adhd-medicines-risks/abstract
     January 01, 2005 - Food and Drug Administration review of its Adverse Event Reporting System (AERS) for cases of sudden … identifying important cardiovascular outcomes, and assessing the overall risk of serious cardiovascular events … ADHD drugs and serious cardiovascular events in children and young adults. N Engl J Med 2011 Nov 1.

405. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Withdrawals due to adverse events were below 10% in all treatment groups. … Withdrawals due to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were similar. … Headache, nausea, and dizziness were the most common lorcaserin-related adverse events. U.S. … Common adverse events were headache, back pain, nasopharyngitis, and nausea.

406. Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/stroke-afib-update/research-2018
     October 30, 2018 - CHADS 2 , CHA 2 DS 2 -VASc, and ABC risk scores have the best evidence to support prediction of stroke events … Higher adverse events (excessive bleeding or procedure-related complications) were observed with LAA … Direct oral anticoagulants (specifically apixaban and dabigatran) demonstrate reductions in stroke events … and reductions (apixaban) or similar (dabigatran) rates in bleeding events when compared with warfarin … Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic

407. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
     November 03, 2011 - o Treatment discontinuation due to adverse effects. … For categorical variables we will abstract the number of events among treatment groups to calculate … percent CI, we will calculate the relative risk and absolute risk difference from the abstracted events … Time course of adverse events most commonly associated with topiramate for migraine prevention. … A systematic review of adverse events in placebo groups of anti-migraine clinical trials.

408. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - • Acute adverse events (AEs) were significantly fewer with PBI compared with WBI, with no apparent … This highlights the need to investigate outcomes of PBI among patients with adverse risk factors. … These advancements result in improved dose homogeneity that may lower the risk for adverse events. … PBI is associated with fewer acute adverse effects, but the risk of IBR among patients treated with … PBI who have adverse clinical or pathologic features is unclear.

409. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - cardiovascular events (MACE) and coronary dissection were significantly lower in the overall analysis … There was a paucity of trials available to evaluate adverse events with any of the embolic protection … conventional PCI 25 trials including 5,534 patients Major adverse cardiac events were significantly … events (MACE) and coronary dissection were significantly lower in the overall analysis and the good … There was a paucity of trials available to evaluate adverse events with any of the embolic protection

410. Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis – An Update of the 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/osteoporosis-bone-fracture/research-protocol
     May 14, 2010 - events will be analyzed for KQ4. … Outcomes: Any reported harms/adverse events (AEs) that can be directly associated with use of an agent … KQ4 assesses the evidence for adverse effects of treatment. … Events.9 Then, a verbatim account of the AE will be recorded on the form. … Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0.

411. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Withdrawals due to adverse events were below 10% in all treatment groups. … Withdrawals due to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were similar. … Headache, nausea, and dizziness were the most common lorcaserin-related adverse events. U.S. … Common adverse events were headache, back pain, nasopharyngitis, and nausea.

412. Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non–Small-Cell Lung Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/lung-cancer-nonsurgical-therapies/research
     June 12, 2013 - sought studies reporting overall survival, cancer-specific survival, local control, symptom relief, adverse … events, and quality of life among our populations of interest. … Outcomes of therapy for all Key Questions included overall survival, adverse effects, and quality of

413. Treatments for Seasonal Allergic Rhinitis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/allergy-seasonal/research-protocol
     March 08, 2012 - events. … events resulting from systemic absorption, such as impaired bone growth, reduced height, suppression … events in SAR research. … Additionally, systematic reviews and meta-analyses that specifically assess adverse events associated … events, and results.

414. Comparative Effectiveness of Pain Management Interventions for Hip Fracture | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hip-fracture-pain/research-protocol
     December 09, 2009 - For KQ3, all reported adverse events (AE) that are directly or indirectly associated to the intervention … Also, adverse events may occur at any point after the treatment is received (e.g., medication adverse … events outcomes AE related to the pain management intervention Mental status Health-related … For the questions on safety and adverse effects, in addition to the above databases, we will search the … National Library of Medicine's TOXLINE® (1965 to present), and Canada’s Adverse Drug Reaction Database

415. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
     January 01, 2019 - events, side effects of interventions (any time frame) o Hospitalization comparison:  Hospital-based … infections and other harms o Antibiotics comparisons:  Side effects/adverse events attributable … events related to procedures, including bleeding and catheter infections  Need for second procedures … o N≥30/arm* • Single group studies o Only for adverse events o N>100† • Longitudinal (Exclude: … events, and side effects of colonoscopy (e.g. perforation, bleeding) Modifiers/Subgroups of interest

416. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review Update - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
     April 01, 2020 - in frequency of intervention-related adverse events or withdrawals. … Table 64 in the full report summarizes reported adverse events for each intervention. … No serious intervention-related adverse events leading to death or disability or requiring intensive … Evidence was low or insufficient for other adverse events. … Acupuncture-related adverse events: a systematic review of the Chinese literature.

417. Bladder-Cancer-Muscle-Invasive Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-muscle-invasive_executive.pdf
     June 01, 2015 - events; withdrawals due to adverse events; and sources of funding. … Although cisplatin is nephrotoxic, renal adverse events were not well reported.28 No study compared … radical cystectomy: adverse events Insufficient There was insufficient evidence from 4 studies of … with grade 3 or 4 hematological adverse events. … Adjuvant chemotherapy vs. no adjuvant chemotherapy: adverse events Insufficient Harms were poorly

418. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/allergy-seasonal_research-protocol.pdf
     March 08, 2012 - events. … events resulting from systemic absorption, such as impaired bone growth, reduced height, suppression … events in SAR research. … Additionally, systematic reviews and meta-analyses that specifically assess adverse events associated … events, and results.

419. Quantitative Synthesis: Chapter 2. Presenting Different Effects for Different Data Types (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
     February 01, 2018 - Example binary data for effect size computation Treatment Events in Treatment Group Treatment n … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the Presence of Treatment-Induced Adverse … Events. … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the Presence of Treatment-Induced Adverse … Events.

420. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
     March 01, 2010 - The adverse events include altered glucose, diabetes mellitus, lymphoid overgrowth, and malignancy. … KQ 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of treatment … Key question 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted … Key question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of