-
effectivehealthcare.ahrq.gov/sites/default/files/s108.pdf
October 01, 2007 - events
on costs. … The costs of adverse drug events
in hospitalized patients. … Adverse Drug Events Prevention Study Group.
JAMA. 1997;277:307–311.
21. … Adverse drug events in
hospitalized patients. … Using a hospital information
system to assess the effects of adverse drug events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - Differences in Harms (Adverse Events)
(KQ 4a)
We analyzed adverse-events data from 92 head-to-head
efficacy … , and somnolence were
commonly and consistently reported adverse events. … events
such as suicidality, seizures, cardiovascular adverse
events, serotonin syndrome, hyponatremia … Other Severe Adverse Events
The existing evidence on the comparative risk for rare
but severe adverse … Adverse-events profiles High Adverse-events profiles, based on 92 efficacy trials and 48 studies of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - in adverse events
methotrexate vs. quality of life from combination therapy of biologic in efficacy … In general, adverse events did not differ significantly
between biologic and synthetic DMARDs. … Studies were
too small to assess reliably differences in rare but
severe adverse events. … Studies, however, were too small to assess
reliably differences in rare but severe adverse events. … The
groups did not differ in serious adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - This
includes:
1) Overall adverse events;
2) Specific adverse events;
3) Withdrawals/time to withdrawal … due to adverse events;
4) Persistence and reversibility of adverse events. … events, withdrawal due to adverse events, persistence
and reversibility of adverse events. … Adverse events include overall events, specific events, withdrawals due to adverse
events, time to withdrawal … due to adverse events, and persistence and reversibility of adverse
events
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
February 01, 2018 - Harms are Adverse Events or
Complications
• Definition of harms:
► Adverse events or complications … Consider Composite
Adverse Events (II)
• “Serious adverse events” or “withdrawal due to
adverse events … Consider Composite Adverse Events (II)
Two composite adverse events are particularly useful to consider … , the first is “serious adverse events” while the second is “withdrawal due to adverse events.” … Consider Composite Adverse Events (I)
6. Consider Composite Adverse Events (II)
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-outcome-measure-harmonization-depression.pdf
November 01, 2020 - Events of
Interest
Adverse Events Depression treatment-related adverse events. … Use of a brief, publicly
available, validated measurement tool to capture adverse events is
recommended … The adverse events measure also required a modification to capture adverse events related to
procedures … Adverse Events Data
The intent of the adverse events measure is to capture all adverse events related … Because of this
concern, the adverse events measure will be calculated using data captured in the EHR
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
July 27, 2023 - The “Protocols for High-Risk Drugs:
Reducing Adverse Drug Events Related to Anticoagulants” as a patient … Action Plan) identified anticoagulants as a leading cause of adverse
drug events.9 For example, between … MHS II10 expanded this scope to include interventions aimed at reducing adverse events
linked to intravenous … events related to anticoagulants. … US
Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - To date, no study has evaluated proximal
clinical measures, long-term effects, and adverse events
among … Gastrointestinal adverse events/problems. … , and consistently report all adverse
events (not using aggregated events). … GI adverse events (range 2-63%) compared with thiazolidinediones
events (range 0-36%) and second-generation … medications in withdrawals due to unspecified adverse events.
events
4&5k.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
May 29, 2025 - $events,$withdrawals$due$to$adverse$events,$serious$adverse$
events$reported,$withdrawal$rates,$switch … &ACEI&or&ARB)& treatment$led$to$a$similar$number$of$adverse$
$ events$and$serious$adverse$events.$& … $ withdrawals$due$to$adverse$events.$
events.$$ $
& &
Angioedema&&
SOE:&Low&(ACEI&vs. … $Moreover,$aliskiren$and$ARB$treatment$led$to$a$similar$number$of$adverse$events,$severe$adverse$events … ,$and$withdrawal$due$to$
adverse$events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - events (RR 0.75, 95% CI 0.70 to 0.80)
and withdrawals due to GI adverse events (RR 0.45,
95% CI 0.33 … , any GI adverse events
(RR 0.31, 95% CI 0.24 to 0.39), and withdrawals due
to GI adverse events (RR … , 95% CI 0.70 to 0.99), but there was no difference
in risk of GI adverse events, withdrawal due to adverse … events, or withdrawal due to GI adverse events. … events and higher risk of dermatologic
adverse compared to oral NSAIDs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_clinician.pdf
September 01, 2016 - is a summary of a systematic review evaluating the evidence regarding the comparative benefits and adverse … events with SGAs when compared with CBT. … events, such as suicidal
ideas and behavior, between SGAs and other therapies. … events and the rates of discontinuation due to adverse
events may be similar for second-step therapies … events
and rates of discontinuation due to adverse events were
similar (1) when patients were switched
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
May 08, 2023 - What is the frequency and severity of medication errors and adverse drug events?
2. … for 39% of all adverse events in the inpatient
setting.3 Of these events, it is estimated that 27% … Medication Errors and Adverse
Drug Events. … September 7, 2019. https://psnet.ahrq.gov/primer/medication-errors-and-
adverse-drug-events. … Adverse drug events in ambulatory care.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - Outcomes: Disorder-specific and -nonspecific adverse events:
1) Overall adverse events.
2) Specific … adverse events:
a. … events include overall events, specific events, study withdrawals
because of adverse events, time to … withdrawal because of adverse events, and
persistence and reversibility of adverse events … • Major adverse events: mortality, cerebrovascular disease-related events,
development of diabetes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes). … Data were insufficient for
adverse events.
18
Table D. … for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes).
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes). … Data were insufficient for
adverse events.
18
Table D. … for adverse events (not for VTE outcomes). … for adverse events (not for VTE outcomes).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
February 01, 2012 - This includes:
• Overall adverse events.
• Specific adverse events. … • Withdrawals and time to withdrawal due to adverse
events. … • Persistence and reversibility of adverse events.
3. … Twelve studies provided adverse-events data for FGAs
versus SGAs. … Adverse events were reported in 36 studies comparing
SGAs with placebo.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - There was no
increase in risk of serious adverse events or withdrawal due to adverse events. … Some nonopioid treatments had frequent overall adverse events and some less frequent
yet serious adverse … effects, while nonpharmacological treatments typically reported few
adverse events.10
Cannabinoids … Other prioritized adverse
events (cannabis use disorder [CUD], psychosis, cognitive deficits) and the … The evidence on adverse events with
cannabis-related products is much less robust than the evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
June 01, 2016 - events per
patient; p=0.02). … The most common
adverse events were fever/infection
and headache in the glucocorticoids-
plus-lidocaine … events with a transforaminal
injection than with an interlaminar injec-
tion (0.46 vs. 0.22 events … Serious adverse events (hospitalization
or surgery) were rare among all patients.
»» There were higher … events
and the risk of adrenal cortisol suppression.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
February 07, 2018 - Outcomes:
We are interested in the following adverse effects for KQ1 and KQ2:
• Any adverse event … , as in those who experienced an adverse events
• Withdrawal due to adverse events
• Serious adverse … Effects
• Adverse events
• Withdrawal due to adverse
events
• Serious adverse events
• Hospitalization … The critical outcomes include suicide,
mortality, hospitalization, serious adverse events, arrhythmias … Meta-analysis of rare binary events in treatment groups with unequal
variability.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - Harms and Adverse Events
a. … events, serious adverse events,
somnolence, nausea, vomiting, constipation,
dizziness, headache, and … adverse events, with no difference in risk of serious adverse events
(SOE: low) … Rates
of adverse events of long-acting opioids in a state
medicaid program. … Opioid medication discontinuation
and risk of adverse opioid-related health care events.