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Showing results for "adverse events".
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdfNovember 27, 2012 - This is in contrast to Telaprevir’s association with dermatological adverse events, which are unique … We have have made distinctions in our report regarding the adverse events for each drug. … This false impression is further reinforced by the consistent pairing of hematological adverse events … Page 69: "… specific harms associated with use of these drugs (such as hematologic adverse events with … boceprevir…" As noted on pages 46 and 47 of this review, hematologic adverse events are not specific
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effectivehealthcare.ahrq.gov/products/methods-prioritization-harms/methodsFebruary 02, 2018 - distinctly from the rigor for assessing benefits; and challenges in synthesis, including evaluation of rare events … Other issues include whether to assess composite harms (e.g., “serious harms” or “withdrawal due to adverse … events”), which might facilitate comparisons between interventions with dissimilar harms, and how to … Meta-Analysis of Rare Binary Adverse Event Data.
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Allergy-Seasonal Executive (pdf file)
effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdfJuly 01, 2013 - Intranasal corticosteroids do not appear to cause adverse events associated with systemic absorption … Adverse events may occur at any point after treatment is received and may impact quality of life directly … Meta- analysis was performed for adverse events that investigators reported as severe or that led to … events are not expected. … events; underrepresentation of populations of interest, especially children and pregnant women; and -
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/improved-cancer-outcomes-protocol_0.pdfDecember 01, 2021 - events and survival? … events and survival? … events and survival? … events • Chemotherapy /radiation therapy limiting toxicity • Post-op complication • NI-related … events and survival among adults w ith cancer w ho are overw eight or obese.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdfDecember 20, 2011 - events: overall adverse events, withdrawals due to adverse events, and specific adverse events (including … KQ 6 looks as the adverse effects of these interventions. … events. … Impact of Events Scale - Revised (IES-R). … caused by traumatic events
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effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdfOctober 01, 2021 - • Adverse effects of the interventions were inadequately reported in many studies. … All studies focused on benefits of physical activity, with inadequate reporting of adverse events in … activities, and intensity of physical activity; incomplete data analysis; inadequate reporting of adverse … events; and relatively few trials considered to be high quality (low risk of bias).
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effectivehealthcare.ahrq.gov/products/cad-women-treatment/research-protocolJanuary 24, 2011 - treatment and revascularization therapies specifically in women is needed to reduce cardiovascular events … cardiovascular events; MI = myocardial infarction; NSTEMI = non–ST-elevation myocardial infarction; … cardiovascular events: death, nonfatal myocardial infarction, stroke, and repeat revascularization … The safety outcomes will be framed to help identify adverse events, including adverse drug reactions, … cardiovascular events MI Myocardial infarction NSTEMI Non–ST-elevation myocardial infarction PCI
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdfFebruary 01, 2018 - PMID: 11252006. http://dx.doi.org/10.1002/sim.650 Rare binary outcomes • For rare binary events ( … e.g., adverse events), few or zero events may occur in one or both trial arms.7,8 ► In this case the … (e.g., adverse events) • PL methods: ► Better account for uncertainty in estimating between-study variance … • For rare binary events: ► Avoid methods that use continuity corrections. … ► For studies with zero events in one arm, or studies with sparse binary data but no zero events,
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effectivehealthcare.ahrq.gov/products/crohns-disease/research-protocolSeptember 01, 2010 - events.13 The first anti-tumor necrosis factor-α (anti-TNF) biologic, infliximab, was approved for Crohn … events. 13 Treatment guidelines and meta-analyses on the management of Crohn’s disease. … events. … events, and patient-reported outcomes. … events.
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/standardized-library-depression-white-paper.pdfMay 01, 2020 - Relationships between events raise a challenge because relationships are often not directly asserted … • FHIR resources for additional relevant events: These might include procedures, encounters, etc … • Temporal aspects for all events: These allow for inferred relationships. 3 Approach … Events of Interest Adverse Events Depression treatment-related adverse events. … Use of a brief, publicly available, validated measurement tool to capture adverse events is recommended
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/standardized-library-depression-white-paper.pdfMay 01, 2020 - Relationships between events raise a challenge because relationships are often not directly asserted … • FHIR resources for additional relevant events: These might include procedures, encounters, etc … • Temporal aspects for all events: These allow for inferred relationships. 3 Approach … Events of Interest Adverse Events Depression treatment-related adverse events. … Use of a brief, publicly available, validated measurement tool to capture adverse events is recommended
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdfDecember 14, 2017 - findings that, in general, low-frequency of adverse events occur during the treatment and only minor … adverse events are reported post procedure. … (Castro, 2010) We added the following to the Adverse Events and Mortality section, after listing … the events for the AIR2 trial: “The investigators state that all adverse events were treated with “ … Serious adverse events attributed to BT were infrequent, and no deaths were reported.”
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdfAugust 09, 2021 - The review will also provide rates of adverse events of the various PBI modalities necessary for shared … In adult women with early stage breast cancer, what are the comparative effectiveness, adverse events … How do the effectiveness, adverse events, and cosmetic outcomes of partial breast irradiation vary by … In adult women with early stage breast cancer, what are the comparative effectiveness, adverse events … events (KQ1-2) Rate of adverse events (noncomparative series of PBI) (KQ 2a) Financial toxicity (KQ
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/updating-treatments-fecal-incontinence-iiiMarch 15, 2021 - symptom burden based on the CCFIS from baseline through 36-months post-treatment Treatment-related adverse … events associated with NASHA/Dx treatment are low and NASHA/Dx demonstrates an excellent safety profile … Dx FI for reducing fecal incontinence episodes is stable for up to 3 years and that the incidence of adverse … events remains low Reduction of fecal incontinence episodes at 6 months was sustained at continued
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effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdfDecember 29, 2020 - administration and study settings (e.g., home, outpatient, emergency room, and inpatient), lack of data on adverse … events due to frequent or long-term intermittent use of medications, and harms associated with newer … Evidence was insufficient to draw conclusions about serious adverse events.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdfSeptember 29, 2011 - treatment and revascularization therapies specifically in women is needed to reduce cardiovascular events … of treatment listed above comprise optimal medical therapy of CAD to reduce future cardiovascular events … cardiovascular events; MI = myocardial infarction; NSTEMI = non–ST-elevation myocardial infarction; … cardiovascular events: death, nonfatal myocardial infarction, stroke, and repeat revascularization … The safety outcomes will be framed to help identify adverse events, including adverse drug reactions
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Evidence Report on the (pdf file)
effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdfSeptember 01, 2010 - events.13 The first anti-tumor necrosis factor-α (anti- TNF) biologic, infliximab, was approved for … events.13 Treatment guidelines and meta-analyses on the management of Crohn’s disease. … events. … events, and patient-reported outcomes. … events -
Obesity (pdf file)
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdfJune 01, 2014 - Withdrawals due to adverse events were below 10% in all treatment groups. … Withdrawals due to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were similar. … Headache, nausea, and dizziness were the most common lorcaserin-related adverse events. U.S. … Common adverse events were headache, back pain, nasopharyngitis, and nausea. -
effectivehealthcare.ahrq.gov/products/antiplatelet-treatment/research-protocolNovember 22, 2011 - cardiovascular events. … cardiovascular events; however they reached contradictory conclusions. … effects of test-directed treatment (including bleeding events and other adverse events such as gastrointestinal … events and liver toxicity) Adverse effects of testing per se (including test-related anxiety and adverse … events secondary to venipuncture).
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effectivehealthcare.ahrq.gov/products/stroke-afib-update/research-2018October 30, 2018 - CHADS 2 , CHA 2 DS 2 -VASc, and ABC risk scores have the best evidence to support prediction of stroke events … Higher adverse events (excessive bleeding or procedure-related complications) were observed with LAA … Direct oral anticoagulants (specifically apixaban and dabigatran) demonstrate reductions in stroke events … and reductions (apixaban) or similar (dabigatran) rates in bleeding events when compared with warfarin … Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic
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