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Showing results for "adverse events".
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341. Evidence Summary - Comparative Effectiveness Review No. 249: Malnutrition in Hospitalized Adults: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-249-malnutrition-hospitalized-adults-evidence-summary.pdf
     October 01, 2021 - length of stay, activities of daily living, discharge disposition, hospital acquired conditions, or adverse … events). … These studies had several shortcomings, including high risk of bias and poor reporting of adverse events

342. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
     February 15, 2017 - events associated with pharmacologic and/or nonpharmacologic treatments (KQ 2). … events outcomes). … The safety outcomes will be framed to help identify adverse events, including those from drug therapies … interest; that is, important characteristics are those that affect baseline (control group) rates of events … , intervention group rates of events, or both.

343. Psychosocial and Pharmacologic Interventions for Disruptive Behavior Disorders in Children and Adolescents: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
     August 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the potential benefits and adverse … Adverse effects of medications reported in included studies were mild or moderate, but the ability … harms reported in the studies were generally mild or moderate and fairly immediate in nature: �– Adverse … events frequently reported with risperidone included weight gain, sedation, and somnolence. �– Adverse … events associated with mixed amphetamine salts included sleep delay, insomnia, and anorexia. �– Atomoxetine

344. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - However, concerns over potential adverse events associated with antiobesity pharmacotherapies significantly … While several experts mentioned the uncertainty of long-term adverse events as a potential barrier … events were reported in 100% of patients in this study. … The potential was tempered by experts’ significant concerns about reported adverse events. … However, multiple experts also noted the significant reported side effects and adverse events and the

345. Migraine-Prevention Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
     June 01, 2013 - For categorical variables we abstracted the number of events among treatment groups to calculate rates … The number of avoided or excess events per population of 1,000 was the difference between the two event … effects, (2) strength of evidence, and (3) number of events attributable to drug administration per … Few clinical trials followed the recommendations from the Task Force on Adverse Events in Migraine … Evaluation and registration of adverse events in clinical drug trials in migraine.

346. Migraine-Adults-Executive-130408 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
     April 01, 2013 - For categorical variables, we abstracted the number of events among treatment groups to calculate rates … We used default software continuity coefficients for 0 events and intention to treat as recommended … The number of avoided or excessive events per population of 1,000 is the difference between the two … Time course of adverse events most commonly associated with topiramate for migraine prevention. … A systematic review of adverse events in placebo groups of anti-migraine clinical trials.

347. Diagnosis of Celiac Disease: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
     July 01, 2016 - evidence regarding the comparative accuracy (the balance of sensitivity and specificity) and possible adverse … Endoscopy with multiple duodenal biopsies has a very low risk of adverse events. 1. … Overview of Clinical Research Evidence Table 3: Summary of Findings and Strength of Evidence for Adverse … Events Associated With Invasive Diagnostic Tests Adverse Events Test Type and No. of Studies (Na) Systematic … testing because of symptoms. �� Evidence was also insufficient to determine the impact of indirect adverse

348. Mass-Casualty-Events-Scarce-Resources Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
     June 01, 2012 - the impact of applicable strategies on health outcomes (e.g., reduced mortality and/or morbidity, adverse … events). … In the decade that followed, the major causes of MCEs in the United States involved natural events, … Forum on Medical and Public Health Preparedness for Catastrophic Events, Institute of Medicine of the … Allocation of Scarce Resources During Mass Casualty Events.

349. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - • Acute adverse events (AEs) were significantly fewer with PBI compared with WBI, with no apparent … This highlights the need to investigate outcomes of PBI among patients with adverse risk factors. … These advancements result in improved dose homogeneity that may lower the risk for adverse events. … PBI is associated with fewer acute adverse effects, but the risk of IBR among patients treated with … PBI who have adverse clinical or pathologic features is unclear.

350. Antibiotics-Respiratory-Infection Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
     January 01, 2016 - drug events, and decreased health care costs. … events along with overall prescribing. … events and efficacy (N = 1 RCT). … events (N = 1 RCT). … Since the absolute numbers of events were low, the estimates are likely to be unstable and could change

351. head-neck-cancer-update-140204 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
     February 04, 2014 - Evidence was insufficient to draw relative conclusions on survival or tumor control; adverse events … events. … Other tools used to assess adverse events include the Subjective, Objective, Management, Analytic (SOMA … Outcomes: KQ 1, 3 & 4: Final outcomes: QoL and adverse events including; radiation induced toxicities … Also, adverse events such as radiation-associated xerostomia and salivary dysfunction, dysphagia, mucositis

352. Future Research Needs for Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRIs) for Treating Hypertension (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
     March 01, 2012 - events (primarily cough). … ACE inhibitor or ARB) Withdrawals due to adverse events: High (ACE inhibitor vs. … events. … In addition, adverse events (including, but not limited to, weight gain, impaired renal function, angioedema … These studies reported additional data on blood pressure lowering, adverse events, and cough, but with

353. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - However, experts noted that patients would likely be concerned about potential adverse events. … The researchers also reported that the most common adverse events “included headache (35%), nausea … (31%), and abdominal pain (25%); 7 patients withdrew because of adverse events (gastrointestinal disorders … events observed; one expert representing a research perspective stated that although teduglutide “ … events.”28 Disruption to health care infrastructure and staffing are less likely, the experts thought

354. Medical Therapies for Locally Advanced Gastric Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
     February 07, 2025 - events (grade 3, 4, 5) • Direct mild treatment adverse events (grade 1, 2) • Indirect adverse … events from treatment (e.g.., long-term opioid use for pain management) N/A Timing All KQs … : Any follow-up duration for grade 3-5 or indirect adverse events and quality of life; minimum of 1 … year for grade 1-2 adverse events; minimum of 3 months for remaining outcomes N/A Setting All … For direct treatment adverse events (AEs) and indirect treatment-related AEs, we will prioritize using

355. renal-update-2015-150115 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
     January 15, 2015 - The risks and adverse events of the drugs are well-understood and include symptomatic hypotension, myalgia … What adverse events and complications have been associated with aggressive medical therapy or renal … , including flash pulmonary edema (including hospitalization) • Other cardiovascular events (cardiac … , cerebrovascular, peripheral vascular) • Adverse events (eg, post-procedure in-hospital or 30-day … [Type text] [Type text] [Type text] • ≥6 months (except adverse

356. Critical Analysis of the Evidence for Patient Safety Practices in Nursing Home Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nursing-home-safety_research-protocol.pdf
     July 22, 2015 - defines safety as “a type of process or structure whose application reduces the probability of an adverse … acquired infection (HAI) and urinary tract infection, excessive weight loss, medication error and adverse … drug events, help with activities of daily living, fecal/urinary incontinence, depressive symptoms, … acquired infection (HAI) and urinary tract infection, excessive weight loss, medication error and adverse … Medication error and adverse drug events Common Format/ Nursing Home Compare QI Medication management

357. Medical Therapies for Locally Advanced Gastric Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
     January 01, 2024 - events (grade 3, 4, 5) • Direct mild treatment adverse events (grade 1, 2) • Indirect adverse … events from treatment (e.g.., long-term opioid use for pain management) N/A Timing All KQs … : Any follow-up duration for grade 3-5 or indirect adverse events and quality of life; minimum of 1 … year for grade 1-2 adverse events; minimum of 3 months for remaining outcomes N/A Setting All … For direct treatment adverse events (AEs) and indirect treatment-related AEs, we will prioritize using

358. Disposition of Comments for Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
     April 25, 2013 - events and mortality is unclear.” … analysis included Moebus 2010 and Untch 2011 (total N=1372), however these studies contributed no events … On- study mortality was typically determined based on adverse event data (e.g., an adverse event with … trials enrolling patients with low underlying risk would be anticipated to have few, or even no, events … Use of risk-differences in a meta-analysis also allows the inclusion of studies where no events occur

359. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
     March 10, 2010 - (i.e., the difference between tam and ral on DCIS, as well as some adverse events). … This was a reasonably straightforward discussion of the adverse events, however, the importance of the … observation that tamoxifen- related serious adverse events in younger (premenopausal) women is not … I believe the presentation format of potential adverse events can alter the patient's or provider's … The adverse events seem to be described in ways that accentuate their probability.

360. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - events will be analyzed for KQ4 … • Outcomes: - Any reported harms/adverse events (AEs) that can be directly associated with use … KQ4 assesses the evidence for adverse effects of treatment. … Events.9 Then, a verbatim account of the AE will be recorded on the form. … Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0.