-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
July 01, 2022 - adverse events according to drug class? … Harms and Adverse Events
a. … adverse events according to drug class? … events, and serious adverse events. … Specific adverse events for each drug class, such as
gastrointestinal events, cardiovascular events,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
September 01, 2014 - The adverse events and harms reported by any
studies included to address any of the other questions
were … used to address questions about harms and
adverse events. … In addition, we searched specifically
for reports of harms and adverse events associated
with the use … Six studies reported
adverse events such as pain and minor rectal bleeding. … None of the included studies reported any adverse events
related to CT or PET/CT.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - The most commonly
reported adverse events were injection site reactions,
flulike symptoms, depression … Serious
adverse events were generally not reported, although
two studies gave rates of about 25 percent … of efficacy and other reasons
not necessarily related to adverse events or side effects. … Dropouts
from observational studies are more likely to bias reporting
toward lack of adverse events … Adverse events and inefficacy or
progression of disability were two expected categories.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
December 01, 2011 - In patients with ACS who are undergoing PCI of
native vessels, how do the rate and type of adverse
events … The outcomes are
separated into adverse events, intermediate outcomes,
and final health outcomes. … The adverse events of note
include coronary dissection, perforation, and prolonged
procedure time. … Only two direct comparative
randomized trials evaluated for adverse events.51,52 Both
of these direct … There was a paucity of trials available to
evaluate adverse events with any of the embolic
protection
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
October 12, 2023 - Outcome Measures Duration of Follow-Up Results - Primary Outcomes Results - Secondary Outcomes Harms and Adverse … Events (AEs), Including Withdrawals Due AEs Funding Source Quality Comments
Ryu, 2023 1 SBRT vs. … AEs by type, number of patients with an AE (cannot calculate n/Ns because no way to tell if multiple events … See above
Addendum Appendix Abbreviations
Abbreviations for Addendum Appendix
Acronym Term
AE adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
December 16, 2011 - events. … We will report adverse events as they are reported by the authors of the study. … Examples of
adverse events that we have identified a priori are listed in KQ5 above. … with an adverse
event. … Hyperglycemia and adverse pregnancy outcome (HAPO) study Cooperative Research
Group.
-
effectivehealthcare.ahrq.gov/products/health-outcomes-competing-risks/abstract
February 11, 2010 - consider multiple possible outcomes, including the primary outcome of interest and other outcomes such as adverse … events or mortality. … exist for quantifying the probability of benefit from an intervention while accounting for competing events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - What adverse events and complications have been associated with aggressive
medical therapy or renal … No Signal
Adverse events:
Consistent to the original CER, the adverse events were not adequately assessed … What adverse events and complications have been associated with aggressive medical therapy or renal artery … Adverse events
The evidence does not adequately
assess comparisons of adverse events
between medical … These adverse events occurred at
different centers and with
Different providers.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
January 01, 2007 - Differences in Harms (Adverse Events) (KQ 4)
We analyzed adverse events data from 72 head-to-head
efficacy … Methods of adverse events assessment in efficacy trials
differed greatly. … Adverse events profiles. … Severe adverse events.
Sexual dysfunction. … Other severe adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - experience, rate of operative delivery (including c-
section), maternal and child health outcomes including adverse … events
Key Questions
from Nominator:
1. … also address issues
around patient monitoring, nursing protocol, collaborative care, and potential adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/opioid-chronic-pain-surveillance-report-3.pdf
June 01, 2022 - Opioids were associated with increased risk of various adverse events,
including withdrawal due to adverse … There were no serious
adverse events with either TENS or opioids. … Harms and Adverse Events:
a. … events, serious
adverse events, overdose, substance misuse,
substance use disorder related outcomes … Harms and Adverse Events:
Key Question 3. Dosing Strategies:
Key Question 4.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-noninvasive-nonpharma.pdf
August 01, 2022 - No significant adverse
events were reported. … No serious adverse events or withdrawal due to adverse
events were reported. … No serious adverse events
were observed. … No
serious adverse events, death, and withdrawal due to
adverse events were reported. … No
patients reported adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
August 01, 2022 - No significant adverse
events were reported. … No serious adverse events or withdrawal due to adverse
events were reported. … No serious adverse events
were observed. … No
serious adverse events, death, and withdrawal due to
adverse events were reported. … No
patients reported adverse events.
-
effectivehealthcare.ahrq.gov/products/migraine-prevention/research
June 11, 2013 - absolute risk differences, pooled them with random-effects models, and calculated numbers of outcome events … Divalproex sodium (one RCT) resulted in treatment discontinuation due to adverse effects more often than … Treatment discontinuation due to adverse effects did not differ between topiramate (two RCTs), trazodone … propranolol was more effective than placebo for preventing episodic migraine in children, with no bothersome adverse
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-are-the-comparative-diagnostic-accuracy-diagnostic-thinking-therapeutic-and-patient-outcome-efficacy-of-non-invasive-tests-for-the-risk-stratification-of-patients-with-coronary-artery-disease
February 27, 2012 - All patient-related benefits, including but not limited to: reduction in hospitalizations, major adverse … cardiovascular events, and mortality
Describe any health-related risks, side effects, or harms that … cardiac catheterization without subsequent percutaneous coronary intervention, hospitalizations, major adverse … cardiovascular events, and mortality
Appropriateness for EHC Program
Does your question include … diagnostic strategies is known, but their relative impacts on clinical end points – major cardiovascular events
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Summary outcomes, adverse events, and strength of evidence of treatments for
CUR in mixed populations … effects
Serious adverse events NS NA
Ghalayini 200513
(n=51)
TURP vs. … effects
Any adverse events NS NA
de Sèze 200217 (n=13)
Botulinum A toxin vs. … effects:
Any adverse events NS NA
Chen 200416 (n=21)
Botulinum A toxin vs. … Summary outcomes, adverse events, and strength of evidence of treatments for CUR in
mixed populations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
November 24, 2014 - events (safety and tolerability): overall adverse events, withdrawals
because of adverse events, serious … adverse events, specific adverse events
(including hyponatremia, seizures, suicidality, hepatotoxicity … events, or drug interactions (pharmacologic and alternative
treatments)
Timing
We will have no … events, results, and adverse events
reported. … events, if reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
November 01, 2023 - Collection of adverse events data was notably inconsistent
across studies. … In particular, although some studies reported all adverse events, others
only reported them in the situation … Trials of topiramate
reported increased risks of many adverse events, including paresthesias, taste … For most serious harms, there was insufficient data to
determine comparative rates of adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
May 01, 2020 - Partogram use: Evidence summary for major outcomes and adverse events
Category Outcome
Study Design … Low
(non-U.S. setting, 1
study)
Adverse
Events
Maternal
Outcomes –
Hemorrhage
3 RCTs24,25,29 … Moderate
(Indirect,
consistent)
Existing SR
was consistent
with RCT
findings
Adverse
Events … High
Adverse
Events
Maternal Outcomes –
Infection
3 RCTs37
(1,933)
2 SRs44-46
(3,475 patients … Low
(Indirect, 1 study)
Adverse
Events
Maternal
Outcomes –
Trauma to the
Pelvic Floor
1 RCT76
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/regenerative-medicine
July 17, 2020 - needs to be improved guidance for the use of these novel treatments, expected outcomes, and risk of adverse … events; eventually a formal guideline should be created.