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  1. effectivehealthcare.ahrq.gov/products/dietary-supplements/research-protocol
    December 21, 2010 - Question 3 . . . clinical or intermediate harms outcomes (e.g., organ toxicity, serious adverse events … , withdrawal due to adverse events)? … Food and Drug Administration's (FDA) definition of serious adverse events will be used.24 d The languages … events Serious adverse events (composite outcome) c Neurologic adverse events (e.g., neuropathy, … events (composite outcome—FDA definition of serious adverse events 24 ), withdrawal due to adverse events
  2. effectivehealthcare.ahrq.gov/products/juvenile-arthritis-dmards/research-protocol
    March 09, 2010 - KQ 3 In children with JIA, does the rate and type of adverse events differ between the various DMARDs … Adverse events: These are specific to the interventions being examined (see Table 2). … In addition, adverse events may occur at any point after the treatment is received. Methods A. … Case control studies are acceptable to assess for adverse events of DMARD treatment (KQ3, KQ4). … Reporting System (AERS) from July 2008 to June 2009 for adverse events related to JIA treatment with
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes-2007.pdf
    January 01, 2007 - Adverse events associated with medical and angioplasty treatments of renal artery stenosis in direct … No data on adverse events in medicine arm Webster 199812 55 (55) Angioplasty (no stent) vs … Adverse events associated with the medical treatment of renal artery stenosis (no new data) Author … Adverse events associated with angioplasty with stent placement treatment of renal artery stenosis (new … Adverse events associated with the surgical treatment of renal artery stenosis (no new data) Author
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
    August 05, 2010 - • Adverse events will be evaluated from studies of the drugs used for osteoarthritis, rheumatoid … Also, adverse events may occur at any point after the treatment is received. IV. Methods A. … We assumed that the adverse events occurred independently and that the logarithm of the rate ratios … After estimating the effect (number of events prevented or caused) for each of the three adverse events … We also pooled clinical success rates and withdrawal due to adverse events from head- to-head trials
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
    July 01, 2022 - adverse events according to drug class? … Harms and Adverse Events a. … adverse events according to drug class? … events, and serious adverse events. … Specific adverse events for each drug class, such as gastrointestinal events, cardiovascular events,
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
    August 01, 2014 - Does the use of procalcitonin guidance reduce antibiotic resistance and antibiotic adverse events? … events of testing (pain, local bleeding, or infection) Adverse events of therapy (persistent … Does the use of procalcitonin guidance reduce antibiotic resistance and antibiotic adverse events? … events of testing (pain, local bleeding, or infection) Adverse events of therapy (persistent … These should include fewer antibiotic adverse events and emergence of drug-resistant pathogens.
  7. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/mhs-IV-epc-grand-rounds-slides.pptx
    January 01, 2023 - events or errors resulting from exposure to the health care delivery system. … drug events related to anticoagulants Hours of service, fatigue, and sleepiness We are embarking … Drug Events Related to Opioids Implementation Guide The Institute for Healthcare Improvement’s guide … events related to RRS are infrequent in both adults and children (insufficient SOE) Barriers, Facilitators … events, reduce caregiver and patient stress, and improve patient/caregiver satisfaction 57 57
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-treatments-for-acute-pain.pdf
    January 01, 2022 - As in the original report, the new trial reported no serious adverse events. … No adverse events were reported in the NSAID arm; other harms were not reported. … No serious adverse events or withdrawal due to adverse events were reported. … reported no postoperative complications of adverse events from cold compression. … There were no adverse events (drowsiness or gastritis) with either the NSAID or acetaminophen.
  9. effectivehealthcare.ahrq.gov/products/gestational-diabetes-screening-diagnosis/research-protocol
    December 16, 2011 - events. … We will report adverse events as they are reported by the authors of the study. … Examples of adverse events that we have identified a priori are listed in KQ5 above. … with an adverse event. … Hyperglycemia and adverse pregnancy outcome (HAPO) study Cooperative Research Group.
  10. effectivehealthcare.ahrq.gov/products/sleep-apnea/research-protocol
    March 15, 2010 - Surgical recovery events Surgical recovery time Post-surgical events Length of intensive care … or hospital stay Intubation failures Extubation failures Harms, Adverse events Any adverse events … (Congestive heart failure symptoms, stroke, arrhythmia events, coronary artery disease events, hypertension … events Any adverse events KQ 6-7 Adherence / Compliance Categorical (adhering or not adhering) … events: No minimum duration Post-surgery: minimum 6 weeks (except adverse events) Prospective
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendixes-surveillance-report-1-nonopioid-trtmts-chronic-pain.pdf
    January 01, 2021 - Harms and Adverse Events a. … events, and serious adverse events (including falls, fractures, motor vehicle accidents), and specific … adverse events, according to drug class? … events, and serious adverse events. … Specific adverse events for each drug class, such as gastrointestinal events, cardiovascular events,
  12. effectivehealthcare.ahrq.gov/products/colorectal-cancer/abstract
    April 14, 2010 - Comparison of adverse events during 5-fluorouracil versus 5-fluorouracil/oxaliplatin adjuvant chemotherapy
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
    December 31, 2013 - • For Key Question 3, conclusions regarding other adverse events are possibly out of date. … Data related to adverse events is listed in Key Questions 2 and 3. … Metformin was associated with more frequent GI adverse events than were DPP-4 inhibitors. … Adverse events (exenatide vs. placebo) were nausea (12% vs. 2%, p = 0.037), vomiting (8% vs. 0%, p … Slightly higher rates of urinary tract infections and adverse events related to osmotic diuresis and
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
    November 01, 2012 - serious adverse events.16-19,38,52 Triple Therapy Regimens With Pegylated Interferon, Ribavirin, … risk of serious adverse events than dual therapy with pegylated interferon alfa-2a plus ribavirin ( … However, serious adverse events were only reported in two trials,18,19 and the rate of serious adverseadverse events with use of protease inhibitors, and the adverse events appear to be self-limited following … There was no difference in risk of withdrawal due to adverse events.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
    May 16, 2013 - The overall rates of complications/major adverse events were under 7%.9,10,15,18-20,25. … There is a low level of evidence that adverse events associated with RFA are relatively uncommon. … Most of the studies did not report the time of occurrence of the adverse events. … Major adverse events associated with RFA are relatively uncommon. … of the various adverse events were not always comparable.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
    June 01, 2022 - Opioids were associated with increased risk of various adverse events, including withdrawal due to adverse … There were no serious adverse events with either TENS or opioids. … Harms and Adverse Events: a. … events, serious adverse events, overdose, substance misuse, substance use disorder related outcomes … Harms and Adverse Events: Key Question 3. Dosing Strategies: Key Question 4.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
    September 02, 2013 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
  18. effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
    September 02, 2013 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
    September 14, 2016 - events due to immunotherapy) • Serious adverse events • Anaphylaxis reaction • Hypersensitivity … In addition, adverse events may occur at any point after treatment is received. IV. … Adverse drug reactions: definitions, diagnosis, and management. … events (AE): An injury caused by medical management–rather than by the underlying disease–which prolongs … wound infections, technical complications, negligence, diagnostic mishaps, therapeutic mishaps, and events
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
    April 01, 2016 - For reviewing adverse events (KQ 4), per our standard approach, we include observational studies. … (SOE: Insufficient) Specific adverse events. … We looked at both withdrawals that investigators attributed to adverse events and overall numbers … There was no difference in cognitive function between groups. 1 Abbreviations: AE=Adverse Events … (SOE: Insufficient) Specific adverse events.

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