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effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_executive.pdf
January 01, 2020 - What adverse events are collected in clinical studies
(Phases I–IV) and in observational studies containing … Our results support most findings of the IOM
report, add conclusions on some adverse events for which … Broad categories such as “injection-related adverse
events,” “systemic adverse events,” “one or more … adverse
events,” or “serious adverse events” were reported rather
than specific AEs. … Common Terminology Criteria for Adverse Events
(CTCAE). Version 4.0. May 28, 2009.
19.
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effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
March 01, 2010 - The adverse events include altered glucose, diabetes mellitus, lymphoid overgrowth, and malignancy. … KQ 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of treatment … Key question 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted … Key question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of
-
effectivehealthcare.ahrq.gov/products/mhs4-computerized-cds/protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
March 01, 2016 - KQ1, 2
KQ1, 2
Adverse
Events
Discon�nua�on of
An�-inflammatory
Therapy KQ5b
KQ5b
(including presence … Observational studies
were also included for rare adverse events. … The most commonly reported adverse
events in trials of febuxostat were abdominal pain,
diarrhea, and … • High-strength evidence supports a lack of difference in
overall adverse events between allopurinol … Adverse events associated
with colchicine drug interactions: Analysis of the public version
of the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
July 19, 2013 - events for patients with HAP, which may result in lower
health care costs. … Rates of antibiotic-related adverse events? … Rates of antibiotic-related adverse events? … Question 3
Does the evidence for morbidity, mortality, antibiotic-related adverse events, clinical … events (e.g.,
organ toxicityd)
Subgroups:
• HAP, VAP, and HCAP
• Immunocompromised
•
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_disposition-comments.pdf
December 20, 2012 - We agree that
interventions for managing adverse
events may be considered patient-
level interventions … effects” “adverse events”, or “side effects.” … We
have replaced adverse effects with
“adverse events” throughout the
document. … We agree that
interventions for managing adverse
events may be considered patient-
level interventions … We agree that
interventions for managing adverse
events may be considered patient-
level interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/methods-report-web-interactive-presentation-appendix-a.pdf
May 29, 2025 - categories) for
• Cure, improvement, satisfaction (n=117 studies)
• Quality of life (n=84 studies)
• Adverse … events (n=138 studies)
4
An interactive tool
5
Level 1
Evidence Graph
for specific
interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - o Treatment discontinuation due to adverse effects. … For categorical variables we will abstract the number of events among treatment
groups to calculate … percent CI, we will calculate the
relative risk and absolute risk difference from the abstracted events … Time course of adverse events most commonly
associated with topiramate for migraine prevention. … A systematic review of adverse events in placebo
groups of anti-migraine clinical trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/high-cholestorol-medicines-update_research-protocol.pdf
December 31, 2013 - events when compared with statin monotherapy. … The CER will examine surrogate markers
of CHD events including lipid levels and atherosclerosis, as … Ridker PM, Rifai N, Pfeffer MA, et al; Cholesterol and Recurrent Events Investigators. … Primary prevention of acute coronary events with
lovastatin in men and women with average cholesterol … Rosuvastatin to
prevent vascular events in men and women with elevated C-‐reactive
protein.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0277_03-10-2008.pdf
January 01, 2008 - the cost of treatment,
the severity of diseases that HSCT is used to treat, and the prevalence of adverse … events associated
with HSCT, a comprehensive review that focuses on both benefits and harms across
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0086_04-01-2009.pdf
January 01, 2009 - any commonly used dietary supplements decrease the
effectiveness of these medications or increase adverse … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
January 01, 2024 - Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events
Evidence-based … Project Title: Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid
and Cardiovascular Events … determinant of plasma lipid
and lipoprotein concentrations, and subsequent cardiovascular (CV) disease events … o Atherosclerotic cardiovascular
disease (total)
o Major adverse cardiac (or cerebral)
events … – total cholesterol; Tg = Triglycerides/Triacylglycerols; apoA = apolipoprotein; MAC[C]E = Major adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
September 01, 2010 - events.13 The first anti-tumor necrosis factor-α (anti-
TNF) biologic, infliximab, was approved for … events.13
Treatment guidelines and meta-analyses on the management of Crohn’s disease. … events. … events, and patient-reported outcomes. … events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-protocol.pdf
July 01, 2023 - scan
patient data for signs of clinical deterioration in order to alert a clinician of a potential adverse … .9-11 One
study found no statistical improvement in the number of rescue events but did find that the … Activation of rapid response system (a process
measure)
• Cardiorespiratory arrest
• Serious adverse … Effectiveness of continuous or intermittent vital signs
monitoring in preventing adverse events on … scan patient data for signs of clinical deterioration in order to alert a clinician of a potential adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
May 01, 2012 - However, adverse
events, especially irritability and moodiness, can lead to discontinuation, and use … Few serious adverse events were noted. … Fewer
individuals discontinue psychostimulants and ATX than guanfacine XR due to adverse events. … We have identified key clinical and adverse events outcomes
as reported in the draft review, which is … Among individuals ages 6 years or older with ADHD, what are the adverse events and
noncompliance rates
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
January 08, 2025 - We will create a comprehensive list of pertinent adverse
events using the Common Terminology Criteria … for Adverse Events (CTCAE) to ease in
their abstraction. … events. … Common Terminology Criteria for
Adverse Events (CTCAE). Version 5.0. November 27, 2017. … The Development of the McHarm Quality Assessment Scale for
adverse events: Delphi Consensus on important
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
June 10, 2024 - We will create a comprehensive list of pertinent adverse
events using the Common Terminology Criteria … for Adverse Events (CTCAE) to ease in
their abstraction. … events. … Common Terminology Criteria for
Adverse Events (CTCAE). Version 5.0. November 27, 2017. … The Development of the McHarm Quality Assessment Scale for
adverse events: Delphi Consensus on important
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - events, mortality, imaging
quality, and diagnostic accuracy. … Food and Drug
Administration Adverse Event Reporting System (AERS). … events, imaging
quality, and diagnostic accuracy. … events (12 studies), or image and diagnostic
quality (2 studies). … , mortality, need for renal replacement
therapy, or other adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - 1.00 to 1.91)
Hospitalization 1 (12,098) SOE = High
No difference (RR 0.97; 95% CI 0.92 to 1.03)
Adverse … No differences in liver function or other
adverse events between therapies. … No differences in liver function or other
adverse events between therapies. … events 2 (18,423) SOE = Moderate
Adverse events occurred in almost equal proportions of
patients in … events 1 (5,599) SOE = Moderate
No differences in liver function or other adverse events
between
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - In addition to effectiveness, decisionmakers need information on potential adverse risks, and
special … Pain, function, pain relief satisfaction and quality of life,
harms/adverse events (including withdrawal … events
KQ 3: Non-invasive non-pharm Therapy:
Pain, function, pain relief satisfaction, quality of … life and quality of
life, harms, adverse events
None
Timing At the following intervals: < 1 day … events in patients
with migraine.