-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/draft-living-review-plant-chronic-pain-e-cohort-studies.xlsx
March 25, 2024 - Events Other Reported Outcomes Funding Source Risk of Bias
21087411 Bestard, 2011 Prospective cohort … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04)
Withdrawals due to adverse … events: 4.65% (10/215) vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/main-apps-surv-rept-1-acute-pain.pdf
February 01, 2022 - As in the original report, the new trial reported no serious
adverse events. … No adverse events were reported in the NSAID arm; other
harms were not reported. … No adverse events were reported. … No serious adverse events or withdrawal due to adverse events were reported.
12
The other two new … reported no postoperative complications of adverse
events from cold compression.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - • Adverse events will be evaluated from studies of the drugs used for
osteoarthritis, rheumatoid … Also, adverse events may
occur at any point after the treatment is received.
IV. Methods
A. … We assumed that the adverse events occurred independently and
that the logarithm of the rate ratios … After estimating the effect
(number of events prevented or caused) for each of the three adverse events … We also pooled clinical success rates and withdrawal due to adverse events from head-
to-head trials
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - functioning, quality of life, sleep,
substance use, suicide- and self-directed violence, withdrawal due to adverse … events, serious adverse events
• Timing:
o No limitation on study duration or length of followup … Quality of life
• Sleep
• Substance use
• Suicide and self-
directed violence
• Withdrawal due to
adverse … events
• Serious adverse events
(KQ 1)
(KQ 2)
4
IV. … Harms outcomes (withdrawals due to adverse events, serious adverse events)
14
APPENDIX
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - functioning, quality of life, sleep,
substance use, suicide- and self-directed violence, withdrawal due to adverse … events, serious adverse events
• Timing:
o No limitation on study duration or length of followup … Quality of life
• Sleep
• Substance use
• Suicide and self-
directed violence
• Withdrawal due to
adverse … events
• Serious adverse events
(KQ 1)
(KQ 2)
4
IV. … Harms outcomes (withdrawals due to adverse events, serious adverse events)
14
APPENDIX
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gaps-womens-health-22.pdf
April 01, 2022 - • Although associations may exist between
psychotropic medications and adverse events,
causality … • Small to moderate, dose-dependent increases in
withdrawal due to adverse events (WDAE) were
found … NSAIDs have increased risk of
serious gastrointestinal, liver, and cardiovascular
adverse events. … • Serious adverse events are rare for all interventions. … Study Design
• More data to determine what adverse events
concern patients the most, and to what
-
effectivehealthcare.ahrq.gov/products/ptsd-adult-treatment/research-protocol
December 20, 2011 - events: overall adverse events, withdrawals due to adverse events, and specific adverse events (including … KQ 6 looks as the adverse effects of these interventions. … events. … Impact of Events Scale - Revised (IES-R). … distress caused by traumatic events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes-2007.pdf
January 01, 2007 - Adverse events associated with medical and angioplasty treatments of renal artery stenosis in direct … No data on adverse
events in medicine
arm
Webster
199812
55
(55)
Angioplasty (no stent)
vs … Adverse events associated with the medical treatment of renal artery stenosis (no new data)
Author … Adverse events associated with angioplasty with stent placement treatment of renal artery stenosis (new … Adverse events associated with the surgical treatment of renal artery stenosis (no new data)
Author
-
effectivehealthcare.ahrq.gov/products/sleep-apnea/research-protocol
March 15, 2010 - Surgical recovery events
Surgical recovery time
Post-surgical events
Length of intensive care … or hospital stay
Intubation failures
Extubation failures
Harms, Adverse events Any adverse events … (Congestive heart failure symptoms, stroke, arrhythmia events, coronary artery disease events, hypertension … events Any adverse events
KQ 6-7
Adherence / Compliance Categorical (adhering or not adhering) … events: No minimum duration
Post-surgery: minimum 6 weeks (except adverse events)
Prospective
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-treatments-for-acute-pain.pdf
January 01, 2022 - As in the original report, the new trial reported no serious
adverse events. … No adverse events were reported in the NSAID arm; other
harms were not reported. … No serious adverse events or withdrawal due to adverse events were reported. … reported no postoperative complications of adverse events from cold
compression. … There were no adverse events (drowsiness or gastritis) with either the NSAID or
acetaminophen.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
August 01, 2014 - Does the use of procalcitonin guidance reduce antibiotic resistance and antibiotic adverse
events? … events of
testing (pain, local
bleeding, or infection)
Adverse events of therapy
(persistent … Does the use of procalcitonin guidance reduce antibiotic resistance and antibiotic adverse
events? … events of
testing (pain, local
bleeding, or infection)
Adverse events of therapy
(persistent … These should include fewer antibiotic adverse events and emergence of
drug-resistant pathogens.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
September 14, 2016 - events due to immunotherapy)
• Serious adverse events
• Anaphylaxis reaction
• Hypersensitivity … In addition, adverse events may
occur at any point after treatment is received.
IV. … Adverse drug reactions: definitions, diagnosis, and
management. … events (AE): An injury caused by medical management–rather than by the
underlying disease–which prolongs … wound infections, technical complications,
negligence, diagnostic mishaps, therapeutic mishaps, and events
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/mhs-IV-epc-grand-rounds-slides.pptx
January 01, 2023 - events or errors resulting from exposure to the health care delivery system. … drug events related to anticoagulants
Hours of service, fatigue, and sleepiness
We are embarking … Drug Events Related to Opioids Implementation Guide
The Institute for Healthcare Improvement’s guide … events related to RRS are infrequent in both adults and children (insufficient SOE)
Barriers, Facilitators … events, reduce caregiver and patient stress, and improve patient/caregiver satisfaction
57
57
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
September 02, 2013 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
September 02, 2013 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - serious adverse
events.16-19,38,52
Triple Therapy Regimens With Pegylated
Interferon, Ribavirin, … risk of serious adverse events
than dual therapy with pegylated interferon alfa-2a plus
ribavirin ( … However, serious adverse events were
only reported in two trials,18,19 and the rate of serious
adverse … adverse events with use of protease inhibitors, and the
adverse events appear to be self-limited following … There was no difference in risk of withdrawal due to
adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - • For Key Question 3, conclusions regarding other adverse events
are possibly out of date. … Data related to adverse events is listed in Key Questions 2 and 3. … Metformin was associated with more frequent
GI adverse events than were DPP-4 inhibitors. … Adverse events (exenatide
vs. placebo) were nausea (12% vs. 2%, p = 0.037), vomiting (8% vs. 0%,
p … Slightly higher rates of urinary tract infections
and adverse events related to osmotic diuresis and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
July 01, 2022 - adverse events according to drug class? … Harms and Adverse Events
a. … adverse events according to drug class? … events, and serious adverse events. … Specific adverse events for each drug class, such as
gastrointestinal events, cardiovascular events,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendixes-surveillance-report-1-nonopioid-trtmts-chronic-pain.pdf
January 01, 2021 - Harms and Adverse Events
a. … events, and
serious adverse events (including falls, fractures, motor vehicle accidents), and specific … adverse events, according to drug class? … events, and serious adverse events. … Specific adverse events for each drug class, such as
gastrointestinal events, cardiovascular events,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - Infrequent adverse effects varied by treatment. … Events
Vaginal
estrogen vs. … Events
Systemic
testosterone +
systemic
estrogen vs. … Er:YAG
hyperstack
NR NR NR Very lowa,f
⨁◯◯◯
Uncertain
NR NR NR N/A
Abbreviations: AE=adverse … imprecision (total sample size much less than OIS of 400)
gDowngraded one level for imprecision (no or few events