-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - As in the original report, the new trial reported no serious
adverse events. … No adverse events were reported in the NSAID arm; other
harms were not reported. … No adverse events were reported. … No serious adverse events or withdrawal due to adverse events were reported.
12
The other two new … reported no postoperative complications of adverse
events from cold compression.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-fecal-incontinence-supporting.pdf
June 19, 2020 - Three of the treatment-related adverse events were assessed as serious. … No serious adverse events occurred. … Adverse
events were collected. … The
most common adverse events (AEs) were proctalgia (13.3%) and pyrexia (9.6%). … No long-term side effects or serious adverse events were reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the effectiveness and adverse … drug events. … events (���). … No evidence was found regarding the
effect of the combination on adverse consequences. … comparative benefits and adverse consequences.
-
effectivehealthcare.ahrq.gov/products/carioverter-difibrillators/abstract
April 14, 2010 - Aim 4: To estimate the incidence of various potential short and long-term adverse events following ICD … following are study outcomes: all-cause death, hospitalization for heart failure and other cardiovascular events … To define these events, we will use previously validated definitions with very high specificity.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/OCD-key-questions.pdf
January 01, 2022 - OCD Diagnosis
(KQ1)
Intervention delivery: different care
settings and care intensities (KQ4)
Adverse … effects of
diagnosis:
Safety outcomes,
adverse events,
misdiagnosis,
unnecessary diagnostics … Adverse effects of treatment:
Safety outcomes, adverse
events
Potential Effect Modifiers
• Severity … Comparator Usual care
Outcomes Accuracy of diagnosis, risk of misdiagnosis, and possible
adverse … function
and competence/need for special accommodations,
quality of life, acceptability of treatment, adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - • Benefits of TT placement must
be weighed against a variety of
adverse events. … Key Question 3: What adverse events, surgical
complications, and sequelae are associated with inserting … Median percentage of patients and ears with adverse events associated with TT
placement
Adverse Event … Other adverse
events, such as hearing loss and cholesteatoma, are likely
confounded by the severity … Future trials would
benefit from standardization and consistent definition of
adverse events.
-
effectivehealthcare.ahrq.gov/products/arthritis-knee-physical-therapy/research
November 06, 2012 - Adverse events were uncommon and not severe enough to deter participants from continuing treatment. … Adverse events were uncommon and not severe enough to deter participants from continuing treatment.
-
effectivehealthcare.ahrq.gov/products/renal-artery-stenosis/research
October 24, 2006 - blood pressure control, preservation of kidney function, flash pulmonary edema, other cardiovascular events … What adverse events and complications have been associated with aggressive medical therapy or renal artery
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - events. … events. … drug events, no response)
Events rates markedly different than in community Event rates in treatment … events) was chosen. … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
February 01, 2014 - , revascularization procedures, serious
adverse events, LDL-c, and HDL-c. … Outcomes and
Timing
Included clinical outcomes—mortality, cardiovascular events, cerebrovascular events … Included adherence and harms outcomes—adherence, serious adverse events (as reported by investigators … ),
withdrawal due to adverse events, cancer, elevated liver transaminases, adverse +musculoskeletal … events, regardless of statin potency.
-
effectivehealthcare.ahrq.gov/sites/default/files/nursing-home-safety_disposition-comments.pdf
May 27, 2016 - can lead to
adverse events. … Peer reviewer #5 Background The list of adverse events is organized poorly. … “Safety events (also known as adverse events include):…”
This is a good place to acknowledge the public … The focus should be on adverse events. … How this relates to harm and adverse
events is not articulated well.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - functioning, quality of life, sleep,
substance use, suicide- and self-directed violence, withdrawal due to adverse … events, serious adverse events
• Timing:
o No limitation on study duration or length of followup … Quality of life
• Sleep
• Substance use
• Suicide and self-
directed violence
• Withdrawal due to
adverse … events
• Serious adverse events
(KQ 1)
(KQ 2)
4
IV. … Harms outcomes (withdrawals due to adverse events, serious adverse events)
14
APPENDIX
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - functioning, quality of life, sleep,
substance use, suicide- and self-directed violence, withdrawal due to adverse … events, serious adverse events
• Timing:
o No limitation on study duration or length of followup … Quality of life
• Sleep
• Substance use
• Suicide and self-
directed violence
• Withdrawal due to
adverse … events
• Serious adverse events
(KQ 1)
(KQ 2)
4
IV. … Harms outcomes (withdrawals due to adverse events, serious adverse events)
14
APPENDIX
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/draft-living-review-plant-chronic-pain-e-cohort-studies.xlsx
March 25, 2024 - Events Other Reported Outcomes Funding Source Risk of Bias
21087411 Bestard, 2011 Prospective cohort … C
% (n/N)
Any adverse event
3 months: 35% (19/49) vs. 47% (30/52) vs. NR, RR for A vs. … B 0.72 (95% CI 0.49 to 1.07)
Serious adverse events: none in any group
Withdrawals due to adverse events … adverse events: 13% (28/215) vs. 19.4% (42/216), RR 0.67 (95% CI 0.43 to 1.04)
Withdrawals due to adverse … events: 4.65% (10/215) vs.
-
effectivehealthcare.ahrq.gov/products/kidney-stone-prevention/research-protocol
June 15, 2011 - The rationale for the shorter required duration for studies reporting adverse effects is that many adverse … events, and adherence. … The quality of RCTs and observational cohort studies reporting adverse events will be evaluated by using … events according to: patient demographic and comorbid characteristics (age, gender, race, baseline chronic … Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled
-
effectivehealthcare.ahrq.gov/products/migraine-prevention/research-2013
April 18, 2013 - with random-effects models and with Bayesian network meta-analysis, and calculated numbers of outcome events … effects, and 26 (95% CI, 10 to 43) would discontinue treatments due to bothersome adverse effects. … Adverse effects leading to treatment discontinuation were examined in 68 RCTs. … effects and treatment discontinuation due to adverse effects. … discontinuation due to adverse effects.
-
effectivehealthcare.ahrq.gov/products/calcineurin-inhibitor/research-protocol
October 14, 2014 - events during therapy for the “intent to treat analysis” in order to determine which patients would … events
Patient adherence
Long-term clinical outcomes
All-cause mortality
Quality of life … after transplant
Major adverse cardiac events
Malignancy
Infections
timing of infections
clinical … The adverse events and harms reported by any study included to address any of the questions will be used … to assess harms and adverse events related to therapeutic monitoring of CNIs and CNI treatment strategies
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gaps-womens-health-22.pdf
April 01, 2022 - • Although associations may exist between
psychotropic medications and adverse events,
causality … • Small to moderate, dose-dependent increases in
withdrawal due to adverse events (WDAE) were
found … NSAIDs have increased risk of
serious gastrointestinal, liver, and cardiovascular
adverse events. … • Serious adverse events are rare for all interventions. … Study Design
• More data to determine what adverse events
concern patients the most, and to what
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
March 09, 2010 - KQ 3: In children with JIA, does the rate and type of adverse events differ
between the various DMARDs … • Adverse events: These are specific to the interventions being examined (see Table
2). … In addition, adverse events may occur at
any point after the treatment is received. … • Case control studies are acceptable to assess for adverse events of DMARD treatment
(KQ3, KQ4) … Event Reporting System (AERS) from July 2008 to June 2009 for
adverse events related to JIA treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/main-apps-surv-rept-1-acute-pain.pdf
February 01, 2022 - As in the original report, the new trial reported no serious
adverse events. … No adverse events were reported in the NSAID arm; other
harms were not reported. … No adverse events were reported. … No serious adverse events or withdrawal due to adverse events were reported.
12
The other two new … reported no postoperative complications of adverse
events from cold compression.