-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - events during therapy for the “intent to treat analysis” in order to determine
which patients would … diabetes after transplant
§ Major adverse cardiac events
§ Malignancy
§ Infections
o timing … events:
• Nephrotoxicity
• New onset diabetes
• Major cardiac events
• Neurologic complications … The adverse events and harms reported by any study included to address any
of the questions will be … used to assess harms and adverse events related to therapeutic
monitoring of CNIs and CNI treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
March 29, 2013 - depression in pregnant women include younger age, non-Latino ethnicity, being without a
partner, traumatic events … effects or withdrawals due to specific adverse events related to
treatment (e.g., hyponatremia, activation … reports
• Withdrawals from study and discontinuation of treatment due to adverse events
Source: … events associated with discontinuation of treatment
• Serious adverse events reported
Fetus, Infant … events (e.g., withdrawal symptoms [neonatal abstinence
symptoms], pulmonary hypertension, respiratory
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
June 15, 2011 - adverse treatment effects may manifest in less than 1 year. … events, and adherence. … The quality of RCTs and observational
cohort studies reporting adverse events will be evaluated by … events according to: patient demographic and comorbid characteristics (age, gender,
race, baseline … Risk of renal stone events in primary
hyperparathyroidism before and after parathyroid surgery: controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
September 03, 2019 - events is
critically important
The specific adverse events that were selected
for this report, and … The specific adverse events that were selected
for this report, and were graded (implying a
higher … The specific adverse events that were selected
for this report, and were graded (implying a
higher … The
protocol for this review does not include the
outcome “severe adverse events”, similar to
total … adverse events but those reported to be
severe by the individual trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
May 05, 2017 - events of tubes without
stating adverse events of
comparative strategies),
which I would urge the … Our descriptive survey of adverse events
associated with TT directly reflects KQ 3 "what
adverse events … and adverse events (“a
variety of adverse events” is not
very specific, the authors should
specify … adverse
events).
Edited to provide specific time frames for KQ 1. … adverse
events rather than
providing a Table only.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
May 05, 2017 - events of tubes without
stating adverse events of
comparative strategies),
which I would urge the … Our descriptive survey of adverse events
associated with TT directly reflects KQ 3 "what
adverse events … and adverse events (“a
variety of adverse events” is not
very specific, the authors should
specify … adverse
events).
Edited to provide specific time frames for KQ 1. … adverse
events rather than
providing a Table only.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - The most commonly
reported adverse events were injection site reactions,
flulike symptoms, depression … Serious
adverse events were generally not reported, although
two studies gave rates of about 25 percent … of efficacy and other reasons
not necessarily related to adverse events or side effects. … Dropouts
from observational studies are more likely to bias reporting
toward lack of adverse events … Adverse events and inefficacy or
progression of disability were two expected categories.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
September 29, 2011 - treatment and revascularization therapies specifically in women is
needed to reduce cardiovascular events … of treatment listed above comprise optimal medical therapy of CAD to
reduce future cardiovascular events … cardiovascular events; MI = myocardial infarction; NSTEMI = non–ST-elevation myocardial infarction; … cardiovascular events: death,
nonfatal myocardial infarction, stroke, and repeat revascularization … The safety outcomes will be framed to help
identify adverse events, including adverse drug reactions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
December 20, 2011 - events: overall adverse events, withdrawals due to adverse events,
and specific adverse events (including … KQ 6 looks as the adverse effects
of these interventions. … events. … Impact of Events Scale - Revised (IES-R). … caused by traumatic
events
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/standardized-library-depression-white-paper.pdf
May 01, 2020 - Relationships between events raise a challenge because relationships are often not directly
asserted … • FHIR resources for additional relevant events: These might include procedures,
encounters, etc … • Temporal aspects for all events: These allow for inferred relationships.
3
Approach … Events of Interest Adverse Events Depression treatment-related adverse events. … Use of a brief, publicly available,
validated measurement tool to capture adverse events is recommended
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/standardized-library-depression-white-paper.pdf
May 01, 2020 - Relationships between events raise a challenge because relationships are often not directly
asserted … • FHIR resources for additional relevant events: These might include procedures,
encounters, etc … • Temporal aspects for all events: These allow for inferred relationships.
3
Approach … Events of Interest Adverse Events Depression treatment-related adverse events. … Use of a brief, publicly available,
validated measurement tool to capture adverse events is recommended
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
February 01, 2024 - Few adverse
drug withdrawal events resulted from deprescribing interventions. … drug events,
adverse drug withdrawal events, mortality)
Implementation measures
(e.g., barriers … Importantly, deprescribing was associated with few adverse drug withdrawal events. … Adverse
drug events in ambulatory care. … Reducing Adverse Drug Events in Older
Adults.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
April 01, 2013 - cardiovascular events (MACE)
and coronary dissection were significantly
lower in the overall analysis … There was a paucity of trials available to
evaluate adverse events with any of the
embolic protection … conventional PCI
25 trials including
5,534 patients
Major adverse cardiac events were
significantly … events (MACE) and coronary dissection were
significantly lower in the overall analysis and the good … There was a paucity of trials available to evaluate
adverse events with any of the embolic protection
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
May 29, 2025 - Outcome Measures Duration of Follow-Up Results - Primary Outcomes Results - Secondary Outcomes Harms and Adverse … Events (AEs), Including Withdrawals Due AEs Funding Source Quality Comments
Ryu, 2023 1 SBRT vs. … AEs by type, number of patients with an AE (cannot calculate n/Ns because no way to tell if multiple events … See above
Addendum Appendix Abbreviations
Abbreviations for Addendum Appendix
Acronym Term
AE adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - Example binary data for effect size computation
Treatment
Events in
Treatment
Group
Treatment
n … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the
Presence of Treatment-Induced Adverse … Events. … Number-Needed-to-Treat-Related Concepts for Assessing Treatment Efficacy in the
Presence of Treatment-Induced Adverse … Events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - Observational
studies were eligible for assessment of rare, serious adverse events. … risk of incident vertebral fracture at
12 months and longer (7 trials, N=826); evidence on serious adverse … events was
sparse and imprecise but did not indicate increased risk (SOE: moderate for vertebral
fracture … , low for serious adverse events) … events, at up to 3 years
following treatment (SOE: low).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
August 31, 2017 - This is particularly a problem for rare
adverse events. … Studies are
required to report any adverse events
that occur during study participation;
however, … For withdrawals, we reported overall
withdrawals and withdrawals due to
adverse events. … TEP 3
Results I believe there was a line that stated
there were no serious adverse events in
the … Nevertheless, we
present each specific adverse
events so that readers can make
these judgments on
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - Outcomes: The outcomes are broken up into adverse events (e.g., failure to deploy the device or
remove … Adverse events, harms and safety issues reported
Question 3:
What are the variables associated with … The outcomes
are broken up into adverse events, intermediate outcomes, and final health outcomes. … The
adverse events of note include failure of the device to employ, breakage or fracture, perforation … outcomes
Mortality
mRS
NIHSS
Barthel Index
GOS
Patients with
Acute
Ischemic
Stroke
Adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
July 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the potential benefits and adverse … Noninvasive nonsurgical fecal incontinence treatments
had few minor adverse effects. … Longer term information on benefits and
adverse effects would better inform clinical decisions for … Substantial and life-
altering adverse events sometimes occur after surgery for
fecal incontinence, … and these events were underidentified
in randomized controlled trials (RCTs) alone.
�� Addressing the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - However, both surgical and radiation treatments
result in significant short- and long-term adverse … events. … Thus, all men who undergo treatment
risk suffering the adverse events of the treatment, while only … events, and costs. … Randomized controlled trials, nonrandomized comparative studies, and cohort
studies; for adverse events