-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
October 07, 2011 - events. … The purpose of this section is to describe the
potential adverse events that may be
encountered in … With
respect to adverse events, an important finding of ONTARGET is that
combination therapy had higher … adverse event rates but no more
benefit than a single drug. … The key questions 1 and 2
specifically examine cardiovascular events and adverse events
between drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - Pharmacological therapies are associated with increased risk
of adverse events when compared with placebo … �» Examples of reported adverse effects included mild bleeding at needling
sites with acupuncture, … events when compared with placebo (��� to ���) … Table 4: Adverse Effects of Interventions for Low Back Pain
Table 3: Nonradicular Chronic Low Back Pain … addiction, overdose, and death
Nonsteroidal
anti-inflammatory
drugs
��Cardiovascular thrombotic events
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/episodic-migraine-surveillance-report-1.pdf
March 01, 2022 - No serious adverse events, death,
or withdrawal due to adverse events were reported.
8
A subgroup … No serious adverse events or withdrawal due to adverse
events were reported. … No adverse events
were reported in either groups. … No
serious adverse events, death, and withdrawal due to
adverse events were reported. … No
significant adverse events were reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
July 01, 2011 - events. … All interventions have the potential for adverse events. … Generally about 5-15% of
CPAP vs. control patients in trials had specific adverse events they considered … Long-term adverse events included speech or voice changes,
difficulties swallowing, airway stenosis, … In smaller
studies, when these adverse events were reported they occurred
in about 2–15% of patients
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - events:
1 serious adverse events: The [(n/N (%)] was 6/127 (5) versus 4/120 (3); p= 0.70
Any adverse … events [(n/N (%)]
1 serious adverse events:
6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events: … -2.5
± 3.0; p< 0.0001
Adverse events (dry mouth)
(7.4%) vs. (2.8%); p<0062)
Quality of life … events [(n/N (%)]
1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events … -2.5 ± 3.0; p< 0.0001
Adverse events (dry mouth)
(7.4%) vs. (2.8%); p<0062)
Quality of life
-
effectivehealthcare.ahrq.gov/products/cancer-anemia-update/research-protocol
June 16, 2010 - Adverse events related to transfusions reported in included studies will be incorporated in the review … As noted in the previous report, transfusion-related adverse events are uncommon. … Adverse effects limited to thromboembolic events, hypertension, rash and similar symptoms, seizures, … rEPO antibodies, and transfusion adverse events.
… effect*” OR “adverse drug reaction*” OR “side effect*” OR “toxic effect*” OR “adverse event*” OR “complication
-
effectivehealthcare.ahrq.gov/products/kidney-stone-prevention/research-protocol
June 15, 2011 - The rationale for the shorter required duration for studies reporting adverse effects is that many adverse … events, and adherence. … The quality of RCTs and observational cohort studies reporting adverse events will be evaluated by using … events according to: patient demographic and comorbid characteristics (age, gender, race, baseline chronic … Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - We did not use a 0.5 correction factor for the adverse events
analysis. … We did not add a 0.5 correction factor for adverse events
analysis. … Finally, we do state explicitly that the study assessed fractures
as adverse events. … events
In the discussion of gastrointestinal adverse events (p. 133),
the report might clarify the … Peer Reviewer
4
General:
Adverse Events
The adverse events section is problematic.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - WARNINGS: INCREASED MORTALITY, SERIOUS CARDIOVASCULAR
EVENTS, THROMBOEMBOLIC EVENTS, STROKE and INCREASED … Adverse events related to transfusions reported in
included studies will be incorporated in the review … As noted in the previous report, transfusion-related
adverse events are uncommon. … Adverse effects limited to thromboembolic
events, hypertension, rash and similar
symptoms, seizures … , rEPO antibodies, and
transfusion adverse events.
-
effectivehealthcare.ahrq.gov/products/osteoarthritis-pain/research-protocol
August 05, 2010 - Also, adverse events may occur at any point after the treatment is received.
Methods
A. … We assumed that the adverse events occurred independently and that the logarithm of the rate ratios was … After estimating the effect (number of events prevented or caused) for each of the three adverse events … , we estimated the net effects on all three serious adverse events using Monte Carlo simulation. … We also pooled clinical success rates and withdrawal due to adverse events from head-to-head trials of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-chronic-pain-review-jan-2020.pdf
January 01, 2020 - Of five studies reporting on
withdrawals from study due to adverse events (WAEs), two reported higher … Specific adverse events of dizziness (mean, 32% vs. 9.5%), nausea (32%
vs. 6%), and sedation (7% vs. … The study reported 4.7 percent of those using cannabis withdrew from the study due to adverse
events … Adverse events were reported in all three placebo-
controlled trials, but heterogeneously. … event; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - • Although associations may exist between psychotropic medications and adverse
events, causality … For child adverse outcomes, we found an association
between benzodiazepine and neonatal intensive care … evidence
available is consistent with some benefit; and (4) some studies suggested some increased
adverse … events, many of which are rare or transient. … events is unclear.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the effectiveness and adverse … drug events. … events (���). … No evidence was found regarding the
effect of the combination on adverse consequences. … comparative benefits and adverse consequences.
-
effectivehealthcare.ahrq.gov/products/arthritis-psoriatric/research-protocol
December 06, 2010 - Many questions remain about the risks of these agents across a spectrum of adverse events from relatively … Like in RA trials, many questions remain about the risks of these agents across a spectrum of adverse … events from relatively minor side effects such as injection site reactions to severe and possibly life-threatening … events
Tolerability
Adherence
Other adverse effects
Timing:
Minimum of three months duration … Also, adverse events may occur at any point after the treatment is received.
Methods
A.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
July 01, 2023 - patient and family perspectives can
be incorporated into patient safety, ultimately reducing risks for adverse … events and preventable
harms. … concurrent or historical
comparison group
• No clear description of
intervention
Outcome Safety
• Adverse … The missing evidence: a systematic review of patients' experiences
of adverse events in health care … Promoting engagement by patients and families to reduce adverse
events in acute care settings: a systematic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - What adverse events and complications have been associated with aggressive medical
therapy or renal … Adverse events (including 30 day mortality)
No new data on adverse event rates among comparative studies … Adverse events (including 30 day mortality)
A total of 22 studies reported adverse events immediately … , though serious long-term adverse events were rare. … Reported adverse events from antihypertensives were relatively minor and
transient.
-
effectivehealthcare.ahrq.gov/products/asthma-immunotherapy/research-protocol
September 14, 2016 - events due to immunotherapy)
Serious adverse events
Anaphylaxis reaction
Hypersensitivity reaction … In addition, adverse events may occur at any point after treatment is received. … Adverse drug reactions: definitions, diagnosis, and management. … Safety terms
Adverse events (AE): An injury caused by medical management–rather than by the underlying … (Food and Drug Administration, 2009)
Serious adverse events (SAE): The event is serious and should
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
October 01, 2011 - Careful attention to details regarding
adverse events and their impact on medication
adherence offers … Limitations include the following: preschool children
experience more doserelated adverse events than … Both interventions are effective, with
no adverse events reported for PBT, while there are
adverse … Fewer children experienced adverse events with MPH
than with DEX. … Concerns about adverse events led to
discontinuation of medications for 15 to 20 percent of
children
-
effectivehealthcare.ahrq.gov/products/copd/research
October 11, 2019 - Antibiotics and corticosteroids are not associated with increase in serious adverse events. … Serious adverse events were not found to be different between most evaluated interventions.
-
effectivehealthcare.ahrq.gov/products/carioverter-difibrillators/abstract
April 14, 2010 - Aim 4: To estimate the incidence of various potential short and long-term adverse events following ICD … following are study outcomes: all-cause death, hospitalization for heart failure and other cardiovascular events … To define these events, we will use previously validated definitions with very high specificity.