-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
July 01, 2012 - drug events) and real (adverse drug events being a subset of the drug
related problems) drug related … Adverse Drug Events
The assessment of a medication therapy management program designed to impact
adverse … We chose a validated research tool to
assess adverse drug events. … The costs associated with adverse drug
events among older adults in the ambulatory
setting. … Risk factors for adverse drug events among
older adults in the ambulatory setting.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
March 29, 2013 - depression in pregnant women include younger age, non-Latino ethnicity, being without a
partner, traumatic events … effects or withdrawals due to specific adverse events related to
treatment (e.g., hyponatremia, activation … reports
• Withdrawals from study and discontinuation of treatment due to adverse events
Source: … events associated with discontinuation of treatment
• Serious adverse events reported
Fetus, Infant … events (e.g., withdrawal symptoms [neonatal abstinence
symptoms], pulmonary hypertension, respiratory
-
effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
April 01, 2020 - in frequency of intervention-related
adverse events or withdrawals. … Table 64 in the full
report summarizes reported adverse events for
each intervention. … No serious intervention-related adverse events
leading to death or disability or requiring intensive … Evidence was low
or insufficient for other adverse events. … Acupuncture-related
adverse events: a systematic review of the Chinese
literature.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - findings that, in general, low-frequency
of adverse events occur during the treatment and only minor … adverse events are reported post procedure. … (Castro, 2010)
We added the following to the Adverse
Events and Mortality section, after listing … the events for the AIR2 trial: “The
investigators state that all adverse
events were treated with “ … Serious adverse events attributed to BT were
infrequent, and no deaths were reported.”
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
September 01, 2014 - The adverse events and harms reported by any
studies included to address any of the other questions
were … used to address questions about harms and
adverse events. … In addition, we searched specifically
for reports of harms and adverse events associated
with the use … Six studies reported
adverse events such as pain and minor rectal bleeding. … None of the included studies reported any adverse events
related to CT or PET/CT.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-patient-family-engagement.pdf
October 01, 2023 - A recent large scale chart
review study showed preventable adverse events occurring in 6.8 percent of … The
missing evidence: a systematic review of
patients' experiences of adverse events in
health care … Adverse in-hospital events are
associated with increased in-hospital
mortality and length of stay in … Outcomes of Patient-Engaged Video Surveillance
on Falls and Other Adverse Events. … Effectiveness of
nonpharmacological interventions to prevent adverse events in the intensive care unit
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the effectiveness and adverse … drug events. … events (���). … No evidence was found regarding the
effect of the combination on adverse consequences. … comparative benefits and adverse consequences.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
January 01, 2023 - Possible that different definitions (for adverse events) or scales (for quality of life) and different … Possible that different definitions (for adverse events) or scales (for quality of life) and different … Objective outcomes (e.g., survival, adverse events) were centrally assessed, reducing potential bias. … assessment, and no protocol or statistical analysis plan is available, but standard approach used to assess adverse … events..
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Withdrawals due to adverse events were below 10% in all
treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Headache, nausea, and dizziness were the most common
lorcaserin-related adverse events. U.S. … Common adverse
events were headache, back pain, nasopharyngitis, and nausea.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_executive.pdf
January 01, 2020 - What adverse events are collected in clinical studies
(Phases I–IV) and in observational studies containing … Our results support most findings of the IOM
report, add conclusions on some adverse events for which … Broad categories such as “injection-related adverse
events,” “systemic adverse events,” “one or more … adverse
events,” or “serious adverse events” were reported rather
than specific AEs. … Common Terminology Criteria for Adverse Events
(CTCAE). Version 4.0. May 28, 2009.
19.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
December 06, 2010 - Many questions remain about the risks of these agents
across a spectrum of adverse events from relatively … Like in RA trials, many
questions remain about the risks of these agents across a spectrum of adverse … events
from relatively minor side effects such as injection site reactions to severe and possibly … Morbidity, mortality and other serious adverse events
ii. … Also, adverse events may occur at any point after the treatment is received.
IV. Methods
A.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
October 01, 2021 - • Adverse effects of the interventions were inadequately reported in many studies. … All studies focused
on benefits of physical activity, with inadequate reporting of adverse events in … activities, and intensity of physical activity; incomplete data
analysis; inadequate reporting of adverse … events; and relatively few trials considered to be
high quality (low risk of bias).
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
December 29, 2020 - administration and study settings (e.g., home, outpatient,
emergency room, and inpatient), lack of data on adverse … events due to frequent or long-term
intermittent use of medications, and harms associated with newer … Evidence
was insufficient to draw
conclusions about serious adverse
events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - cardiovascular events. … cardiovascular events; however they reached
contradictory conclusions. … effects of test-directed treatment (including bleeding events and other
adverse events such as gastrointestinal … events and liver toxicity)
o Adverse effects of testing per se (including test-related anxiety and … adverse
events secondary to venipuncture)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
January 01, 2024 - Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events
Evidence-based Practice … Protocol
Project Title: Dietary Saturated Fat Replacement and Plasma Lipid and
Cardiovascular Events … determinant of plasma lipid
and lipoprotein concentrations, and subsequent cardiovascular (CV) disease events … o Atherosclerotic cardiovascular
disease (total)
o Major adverse cardiac (or
cerebral) events … TC
– total cholesterol; Tg = Triglycerides/Triacylglycerols; apoA = apolipoprotein; MAC[C]E = Major adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Withdrawals due to adverse events were below 10% in all
treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Headache, nausea, and dizziness were the most common lorcaserin-related
adverse events. U.S. … Common
adverse events were headache, back pain, nasopharyngitis, and nausea.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
January 08, 2025 - We will create a comprehensive list of pertinent adverse
events using the Common Terminology Criteria … for Adverse Events (CTCAE) to ease in
their abstraction. … events. … Common Terminology Criteria for
Adverse Events (CTCAE). Version 5.0. November 27, 2017. … The Development of the McHarm Quality Assessment Scale for
adverse events: Delphi Consensus on important
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - PMID: 11252006. http://dx.doi.org/10.1002/sim.650
Rare binary outcomes
• For rare binary events ( … e.g., adverse events), few or zero events may
occur in one or both trial arms.7,8
► In this case the … (e.g., adverse events)
• PL methods:
► Better account for uncertainty in estimating between-study variance … • For rare binary events:
► Avoid methods that use continuity corrections. … ► For studies with zero events in one arm, or studies with sparse binary data
but no zero events,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - experience, rate of operative delivery (including c-
section), maternal and child health outcomes including adverse … events
Key Questions
from Nominator:
1. … also address issues
around patient monitoring, nursing protocol, collaborative care, and potential adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - The most commonly
reported adverse events were injection site reactions,
flulike symptoms, depression … Serious
adverse events were generally not reported, although
two studies gave rates of about 25 percent … of efficacy and other reasons
not necessarily related to adverse events or side effects. … Dropouts
from observational studies are more likely to bias reporting
toward lack of adverse events … Adverse events and inefficacy or
progression of disability were two expected categories.