-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Withdrawals due to adverse events were below 10% in all
treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Headache, nausea, and dizziness were the most common
lorcaserin-related adverse events. U.S. … Common adverse
events were headache, back pain, nasopharyngitis, and nausea.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - experience, rate of operative delivery (including c-
section), maternal and child health outcomes including adverse … events
Key Questions
from Nominator:
1. … also address issues
around patient monitoring, nursing protocol, collaborative care, and potential adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - PMID: 11252006. http://dx.doi.org/10.1002/sim.650
Rare binary outcomes
• For rare binary events ( … e.g., adverse events), few or zero events may
occur in one or both trial arms.7,8
► In this case the … (e.g., adverse events)
• PL methods:
► Better account for uncertainty in estimating between-study variance … • For rare binary events:
► Avoid methods that use continuity corrections. … ► For studies with zero events in one arm, or studies with sparse binary data
but no zero events,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - cardiovascular events. … cardiovascular events; however they reached
contradictory conclusions. … effects of test-directed treatment (including bleeding events and other
adverse events such as gastrointestinal … events and liver toxicity)
o Adverse effects of testing per se (including test-related anxiety and … adverse
events secondary to venipuncture)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
September 22, 2011 - events. … Nonadherence to HCV treatment may be associated with
a lack of management of adverse events,5,10 higher … events. … Although neither study found adverse
events associated with the use of epoetin or citalopram,
both … Both studies
reported that no patients showed adverse events related to
the use of these medications
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Withdrawals due to adverse events were below 10% in all
treatment groups. … Withdrawals due
to adverse events were below 10% in both treatment groups. … The rates of serious adverse events in the two groups were
similar. … Headache, nausea, and dizziness were the most common lorcaserin-related
adverse events. U.S. … Common
adverse events were headache, back pain, nasopharyngitis, and nausea.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
November 27, 2012 - This is in contrast to Telaprevir’s
association with dermatological adverse events,
which are unique … We have have made distinctions in our
report regarding the adverse events for each drug. … This false
impression is further reinforced by the consistent
pairing of hematological adverse events … Page 69: "… specific
harms associated with use of these drugs (such as
hematologic adverse events with … boceprevir…" As
noted on pages 46 and 47 of this review, hematologic
adverse events are not specific
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
January 01, 2024 - Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events
Evidence-based Practice … Protocol
Project Title: Dietary Saturated Fat Replacement and Plasma Lipid and
Cardiovascular Events … determinant of plasma lipid
and lipoprotein concentrations, and subsequent cardiovascular (CV) disease events … o Atherosclerotic cardiovascular
disease (total)
o Major adverse cardiac (or
cerebral) events … TC
– total cholesterol; Tg = Triglycerides/Triacylglycerols; apoA = apolipoprotein; MAC[C]E = Major adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-patient-family-engagement.pdf
October 01, 2023 - A recent large scale chart
review study showed preventable adverse events occurring in 6.8 percent of … The
missing evidence: a systematic review of
patients' experiences of adverse events in
health care … Adverse in-hospital events are
associated with increased in-hospital
mortality and length of stay in … Outcomes of Patient-Engaged Video Surveillance
on Falls and Other Adverse Events. … Effectiveness of
nonpharmacological interventions to prevent adverse events in the intensive care unit
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
January 01, 2016 - events (including adverse patient experiences such as
pain or infection at the aspiration site, effects … events, were
included if they addressed Key Question 2 (adverse events
or other negative outcomes … tests used to diagnose gout.28 This study
reported no adverse events associated with aspiration of … No studies were identified
that documented any adverse events associated with
diagnostic tests included … Events
Adverse events associated with procedures
US Insufficient No conclusion possible
DECT Low Evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
April 18, 2013 - Among other adverse events, beta blockers may be
associated with depression, possible exacerbation of … Based on these
known adverse events the conclusion that beta
blockers are without bothersome harms … events, compared with 10% of the 445
placebo‐treated patients. … Most
topiramate‐associated adverse events were mild or
moderate in severity, and they occurred more … We analyzed specific
safety outcome (specific adverse effects or
treatment discontinuation due to adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
March 10, 2010 - "Increasing statin dose or potency could potentially increase
frequency of important adverse events … Revised as follows:
For clinical outcomes and serious adverse events, we anticipated that
the available … Information on adverse events was only collected if dichotomous
data were available (number of people … A decline in cellular and physiologic system increases vulnerability to
adverse events of treatment. … Information on adverse events were only collected if dichotomous
data were available (number of people
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - Comparison of the sample size, primary outcome, and withdrawals due to adverse
events reported in the … ClinicalTrials.gov began to mandate reporting of adverse
events in September 2009 as serious adverse … events and non-serious adverse events. … We
compared the total adverse events reported in ClinicalTrials.gov with the total reported in
the … CT.gov reported more adverse
events.
-
effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
January 01, 2007 - Developing Indicators of Inpatient Adverse Drug
Events Through Non-Linear Analysis Using Administrative … Real-Time Vaccine Safety Surveillance for the
Early Detection of Adverse Events. … Evaluation and Overview
of the National Electronic Injury Surveillance System- Cooperative Adverse … A Simulation-Based Evaluation of
Methods to Estimate the Impact of an Adverse Event on Hospital Length
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
December 01, 2017 - • Serious adverse events,
events leading to treatment
discontinuation, and treatment site
infections … Adverse Events, All BCC Lesions
In Table B drugs were most likely to have adverse events
leading to … Events
Leading to
Discontinuation
(95% CI)
Serious
Adverse
Events (95%
CI)
Adverse
Events: … Adverse Events, All SCCIS Lesions
In Table C the highest mean frequency of adverse events
leading to … Adverse events
were inconsistently reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
December 16, 2011 - events. … We will report adverse events as they are reported by the authors of the study. … Examples of
adverse events that we have identified a priori are listed in KQ5 above. … with an adverse
event. … Hyperglycemia and adverse pregnancy outcome (HAPO) study Cooperative Research
Group.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Summary outcomes, adverse events, and strength of evidence of treatments for
CUR in mixed populations … effects
Serious adverse events NS NA
Ghalayini 200513
(n=51)
TURP vs. … effects
Any adverse events NS NA
de Sèze 200217 (n=13)
Botulinum A toxin vs. … effects:
Any adverse events NS NA
Chen 200416 (n=21)
Botulinum A toxin vs. … Summary outcomes, adverse events, and strength of evidence of treatments for CUR in
mixed populations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - Adverse effects of intervention(s): withdrawals due to
adverse events, nausea/vomiting, diarrhea, anorexia … Naltrexone
One study 24 (n=128) reported no serious adverse
events, but an increase in sleepiness … Baclofen
There were no serious adverse events related to
baclofen in two studies: one RCT (n=56), 23 … The
majority of serious adverse events in the placebo
group (88%) and the nalmefene group (76%) were … They reported mental slowing, a reduction in verbal
fluency and working memory as adverse events
among
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - Infrequent adverse effects varied by treatment. … Events
Vaginal
estrogen vs. … Events
Systemic
testosterone +
systemic
estrogen vs. … Er:YAG
hyperstack
NR NR NR Very lowa,f
⨁◯◯◯
Uncertain
NR NR NR N/A
Abbreviations: AE=adverse … imprecision (total sample size much less than OIS of 400)
gDowngraded one level for imprecision (no or few events
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
September 14, 2016 - events due to immunotherapy)
• Serious adverse events
• Anaphylaxis reaction
• Hypersensitivity … In addition, adverse events may
occur at any point after treatment is received.
IV. … Adverse drug reactions: definitions, diagnosis, and
management. … events (AE): An injury caused by medical management–rather than by the
underlying disease–which prolongs … wound infections, technical complications,
negligence, diagnostic mishaps, therapeutic mishaps, and events