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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
    October 07, 2011 - events. … The purpose of this section is to describe the potential adverse events that may be encountered in … With respect to adverse events, an important finding of ONTARGET is that combination therapy had higher … adverse event rates but no more benefit than a single drug. … The key questions 1 and 2 specifically examine cardiovascular events and adverse events between drug
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
    November 01, 2016 - Pharmacological therapies are associated with increased risk of adverse events when compared with placebo … �» Examples of reported adverse effects included mild bleeding at needling sites with acupuncture, … events when compared with placebo (��� to ���) … Table 4: Adverse Effects of Interventions for Low Back Pain Table 3: Nonradicular Chronic Low Back Pain … addiction, overdose, and death Nonsteroidal anti-inflammatory drugs ��Cardiovascular thrombotic events
  3. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/episodic-migraine-surveillance-report-1.pdf
    March 01, 2022 - No serious adverse events, death, or withdrawal due to adverse events were reported. 8 A subgroup … No serious adverse events or withdrawal due to adverse events were reported. … No adverse events were reported in either groups. … No serious adverse events, death, and withdrawal due to adverse events were reported. … No significant adverse events were reported.
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
    July 01, 2011 - events. … All interventions have the potential for adverse events. … Generally about 5-15% of CPAP vs. control patients in trials had specific adverse events they considered … Long-term adverse events included speech or voice changes, difficulties swallowing, airway stenosis, … In smaller studies, when these adverse events were reported they occurred in about 2–15% of patients
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
    October 29, 2012 - events: 1 serious adverse events: The [(n/N (%)] was 6/127 (5) versus 4/120 (3); p= 0.70 Any adverseevents [(n/N (%)] 1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70 Any adverse events: … -2.5 ± 3.0; p< 0.0001 Adverse events (dry mouth) (7.4%) vs. (2.8%); p<0062) Quality of life … events [(n/N (%)] 1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70 Any adverse events … -2.5 ± 3.0; p< 0.0001 Adverse events (dry mouth) (7.4%) vs. (2.8%); p<0062) Quality of life
  6. effectivehealthcare.ahrq.gov/products/cancer-anemia-update/research-protocol
    June 16, 2010 - Adverse events related to transfusions reported in included studies will be incorporated in the review … As noted in the previous report, transfusion-related adverse events are uncommon. … Adverse effects limited to thromboembolic events, hypertension, rash and similar symptoms, seizures, … rEPO antibodies, and transfusion adverse events.   … effect*” OR “adverse drug reaction*” OR “side effect*” OR “toxic effect*” OR “adverse event*” OR “complication
  7. effectivehealthcare.ahrq.gov/products/kidney-stone-prevention/research-protocol
    June 15, 2011 - The rationale for the shorter required duration for studies reporting adverse effects is that many adverseevents, and adherence. … The quality of RCTs and observational cohort studies reporting adverse events will be evaluated by using … events according to: patient demographic and comorbid characteristics (age, gender, race, baseline chronic … Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
    March 01, 2012 - We did not use a 0.5 correction factor for the adverse events analysis. … We did not add a 0.5 correction factor for adverse events analysis. … Finally, we do state explicitly that the study assessed fractures as adverse events. … events In the discussion of gastrointestinal adverse events (p. 133), the report might clarify the … Peer Reviewer 4 General: Adverse Events The adverse events section is problematic.
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
    June 16, 2010 - WARNINGS: INCREASED MORTALITY, SERIOUS CARDIOVASCULAR EVENTS, THROMBOEMBOLIC EVENTS, STROKE and INCREASED … Adverse events related to transfusions reported in included studies will be incorporated in the review … As noted in the previous report, transfusion-related adverse events are uncommon. … Adverse effects limited to thromboembolic events, hypertension, rash and similar symptoms, seizures … , rEPO antibodies, and transfusion adverse events.
  10. effectivehealthcare.ahrq.gov/products/osteoarthritis-pain/research-protocol
    August 05, 2010 - Also, adverse events may occur at any point after the treatment is received. Methods A. … We assumed that the adverse events occurred independently and that the logarithm of the rate ratios was … After estimating the effect (number of events prevented or caused) for each of the three adverse events … , we estimated the net effects on all three serious adverse events using Monte Carlo simulation. … We also pooled clinical success rates and withdrawal due to adverse events from head-to-head trials of
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-chronic-pain-review-jan-2020.pdf
    January 01, 2020 - Of five studies reporting on withdrawals from study due to adverse events (WAEs), two reported higher … Specific adverse events of dizziness (mean, 32% vs. 9.5%), nausea (32% vs. 6%), and sedation (7% vs. … The study reported 4.7 percent of those using cannabis withdrew from the study due to adverse eventsAdverse events were reported in all three placebo- controlled trials, but heterogeneously. … event; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse events.
  12. effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
    April 01, 2021 - • Although associations may exist between psychotropic medications and adverse events, causality … For child adverse outcomes, we found an association between benzodiazepine and neonatal intensive care … evidence available is consistent with some benefit; and (4) some studies suggested some increased adverseevents, many of which are rare or transient. … events is unclear.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
    March 01, 2016 - This is a summary of a systematic review evaluating the evidence regarding the effectiveness and adverse … drug events. … events (���). … No evidence was found regarding the effect of the combination on adverse consequences. … comparative benefits and adverse consequences.
  14. effectivehealthcare.ahrq.gov/products/arthritis-psoriatric/research-protocol
    December 06, 2010 - Many questions remain about the risks of these agents across a spectrum of adverse events from relatively … Like in RA trials, many questions remain about the risks of these agents across a spectrum of adverseevents from relatively minor side effects such as injection site reactions to severe and possibly life-threatening … events Tolerability Adherence Other adverse effects Timing: Minimum of three months duration … Also, adverse events may occur at any point after the treatment is received. Methods A.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
    July 01, 2023 - patient and family perspectives can be incorporated into patient safety, ultimately reducing risks for adverseevents and preventable harms. … concurrent or historical comparison group • No clear description of intervention Outcome Safety • Adverse … The missing evidence: a systematic review of patients' experiences of adverse events in health care … Promoting engagement by patients and families to reduce adverse events in acute care settings: a systematic
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
    January 01, 2007 - What adverse events and complications have been associated with aggressive medical therapy or renal … Adverse events (including 30 day mortality) No new data on adverse event rates among comparative studies … Adverse events (including 30 day mortality) A total of 22 studies reported adverse events immediately … , though serious long-term adverse events were rare. … Reported adverse events from antihypertensives were relatively minor and transient.
  17. effectivehealthcare.ahrq.gov/products/asthma-immunotherapy/research-protocol
    September 14, 2016 - events due to immunotherapy) Serious adverse events Anaphylaxis reaction Hypersensitivity reaction … In addition, adverse events may occur at any point after treatment is received. … Adverse drug reactions: definitions, diagnosis, and management. … Safety terms Adverse events (AE): An injury caused by medical management–rather than by the underlying … (Food and Drug Administration, 2009) Serious adverse events (SAE): The event is serious and should
  18. effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
    October 01, 2011 - Careful attention to details regarding adverse events and their impact on medication adherence offers … Limitations include the following: preschool children experience more dose­related adverse events than … Both interventions are effective, with no adverse events reported for PBT, while there are adverse … Fewer children experienced adverse events with MPH than with DEX. … Concerns about adverse events led to discontinuation of medications for 15 to 20 percent of children
  19. effectivehealthcare.ahrq.gov/products/copd/research
    October 11, 2019 - Antibiotics and corticosteroids are not associated with increase in serious adverse events. … Serious adverse events were not found to be different between most evaluated interventions.
  20. effectivehealthcare.ahrq.gov/products/carioverter-difibrillators/abstract
    April 14, 2010 - Aim 4: To estimate the incidence of various potential short and long-term adverse events following ICD … following are study outcomes: all-cause death, hospitalization for heart failure and other cardiovascular events … To define these events, we will use previously validated definitions with very high specificity.

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