-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - functioning, quality of life, sleep,
substance use, suicide- and self-directed violence, withdrawal due to adverse … events, serious adverse events
• Timing:
o No limitation on study duration or length of followup … Quality of life
• Sleep
• Substance use
• Suicide and self-
directed violence
• Withdrawal due to
adverse … events
• Serious adverse events
(KQ 1)
(KQ 2)
4
IV. … Harms outcomes (withdrawals due to adverse events, serious adverse events)
14
APPENDIX
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
January 01, 2024 - that have potential analgesic effects as well as the
potential for addiction, misuse, and serious adverse … There may be no increase in
risk of serious adverse events (SOE: low) or withdrawal due to adverse events … Other prioritized adverse events
(cannabis use disorder [CUD], psychosis, cognitive deficits) and the … events, such as CUD, psychosis, and cognitive deficits. … Compared with placebo, these interventions resulted in greater risk of common adverse
events (dizziness
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - However, concerns over potential
adverse events associated with antiobesity pharmacotherapies have … cardiovascular events.
2
Amid concerns over various adverse events, three drugs in late-phase development … Another expert with a research perspective expressed concern about adverse gastrointestinal events … The potential was tempered by experts’ significant concerns about adverse events
reported thus far. … However, multiple experts also noted the significant side effects and adverse events reported and the
-
effectivehealthcare.ahrq.gov/sites/default/files/nursing-home-safety_disposition-comments.pdf
May 27, 2016 - can lead to
adverse events. … Peer reviewer #5 Background The list of adverse events is organized poorly. … “Safety events (also known as adverse events include):…”
This is a good place to acknowledge the public … The focus should be on adverse events. … How this relates to harm and adverse
events is not articulated well.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
July 01, 2014 - reports, adverse events
associated with discontinuation of treatment, and
serious adverse events … • Withdrawals from study and discontinuation of
treatment due to adverse events
• All-cause mortality … events,
discontinuation due to adverse events, and weight
gain. … events Insufficient;
no conclusions drawn
Sertraline Sertraline + interpersonal
psychotherapy
Adverse … therapy Adverse events Insufficient;
SSRI = selective serotonin reuptake inhibitor, TCA = tricyclic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
November 26, 2024 - cognitive impairment, and
substance use disorders.10 This project will investigate the epidemiology and adverse … events)
Psychological outcomes
o Long-term
Health measures
Psychological outcomes
Employment … term")) OR (title: ("long term")) OR (title: ("longer
term")) OR (title: (outcomes)) OR (title: ("adverse … event")) OR (title: ("adverse
events")) OR (title: (consequence)) OR (title: (consequences)) OR (title … event")) OR (abstract: ("adverse
events")) OR (abstract: (consequence)) OR (abstract: (consequences
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes-2007.pdf
January 01, 2007 - Adverse events associated with medical and angioplasty treatments of renal artery stenosis in direct … No data on adverse
events in medicine
arm
Webster
199812
55
(55)
Angioplasty (no stent)
vs … Adverse events associated with the medical treatment of renal artery stenosis (no new data)
Author … Adverse events associated with angioplasty with stent placement treatment of renal artery stenosis (new … Adverse events associated with the surgical treatment of renal artery stenosis (no new data)
Author
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
January 01, 2017 - events ���
Subgroup of 1 RCT 2269 Age and race do not affect the efficacy of either drug ���
Prophylactic … �� Gastrointestinal symptoms, fatigue, and headache
�� Rare adverse effects include leukopenia, aplastic … effects include bone marrow suppression, aseptic meningitis, and dermatological adverse events
�� Serious … adverse effects include gastrointestinal perforations, ulcers, and increased risk of heart attack or … effects include cardiovascular thromboembolic events, hepatic failure, TEN, SJS, and DRESS
NSAIDs =
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
June 01, 2022 - Opioids were associated with increased risk of various adverse events,
including withdrawal due to adverse … There were no serious
adverse events with either TENS or opioids. … Harms and Adverse Events:
a. … events, serious
adverse events, overdose, substance misuse,
substance use disorder related outcomes … Harms and Adverse Events:
Key Question 3. Dosing Strategies:
Key Question 4.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
July 01, 2022 - adverse events according to drug class? … Harms and Adverse Events
a. … adverse events according to drug class? … events, and serious adverse events. … Specific adverse events for each drug class, such as
gastrointestinal events, cardiovascular events,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - • For Key Question 3, conclusions regarding other adverse events
are possibly out of date. … Data related to adverse events is listed in Key
Questions 2 and 3. … Metformin was associated with more frequent
GI adverse events than were DPP-4 inhibitors. … Adverse events (exenatide
vs. placebo) were nausea (12% vs. 2%, p = 0.037), vomiting (8% vs. 0%,
p … Slightly higher rates of urinary tract infections
and adverse events related to osmotic diuresis and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - As in the original report, the new trial reported no serious
adverse events. … No adverse events were reported in the NSAID arm; other
harms were not reported. … No adverse events were reported. … No serious adverse events or withdrawal due to adverse events were reported.
12
The other two new … reported no postoperative complications of adverse
events from cold compression.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - • Benefits of TT placement must
be weighed against a variety of
adverse events. … Key Question 3: What adverse events, surgical
complications, and sequelae are associated with inserting … Median percentage of patients and ears with adverse events associated with TT
placement
Adverse Event … Other adverse
events, such as hearing loss and cholesteatoma, are likely
confounded by the severity … Future trials would
benefit from standardization and consistent definition of
adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - events. … events. … drug events, no response)
Events rates markedly different than in community Event rates in treatment … events) was chosen. … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - events:
1 serious adverse events: The [(n/N (%)] was 6/127 (5) versus 4/120 (3); p= 0.70
Any adverse … events [(n/N (%)]
1 serious adverse events:
6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events: … -2.5
± 3.0; p< 0.0001
Adverse events (dry mouth)
(7.4%) vs. (2.8%); p<0062)
Quality of life … events [(n/N (%)]
1 serious adverse events: 6/127 (5) vs. 4/120 (3); p= 0.70
Any adverse events … -2.5 ± 3.0; p< 0.0001
Adverse events (dry mouth)
(7.4%) vs. (2.8%); p<0062)
Quality of life
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - Peer Reviewer #3 Results (Pg 52) One reason for the low adverse events rate in the etanercept studies … are the active run-in periods that excluded children who had adverse
events. … During the double-blind phase
(Period B), serious adverse events occurred in two patients in the
placebo … Acute infusional adverse events were reported
in one (2%) patient in the abatacept group and two (3% … The adverse events data from
that study are included in the Appendix.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - • Adverse events will be evaluated from studies of the drugs used for
osteoarthritis, rheumatoid … Also, adverse events may
occur at any point after the treatment is received.
IV. Methods
A. … We assumed that the adverse events occurred independently and
that the logarithm of the rate ratios … After estimating the effect
(number of events prevented or caused) for each of the three adverse events … We also pooled clinical success rates and withdrawal due to adverse events from head-
to-head trials
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
May 16, 2013 - The overall rates of complications/major adverse events
were under 7%.9,10,15,18-20,25. … There is a low level of evidence that adverse events
associated with RFA are relatively uncommon. … Most of the studies did not
report the time of occurrence of the adverse events. … Major adverse events associated with RFA are
relatively uncommon. … of the various
adverse events were not always comparable.
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
October 01, 2011 - Careful attention to details regarding
adverse events and their impact on medication
adherence offers … Limitations include the following: preschool children
experience more doserelated adverse events than … Both interventions are effective, with
no adverse events reported for PBT, while there are
adverse … Fewer children experienced adverse events with MPH
than with DEX. … Concerns about adverse events led to
discontinuation of medications for 15 to 20 percent of
children
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - What adverse events and complications have been associated with aggressive
medical therapy or renal … No Signal
Adverse events:
Consistent to the original CER, the adverse events were not adequately assessed … What adverse events and complications have been associated with aggressive medical therapy or renal artery … Adverse events
The evidence does not adequately
assess comparisons of adverse events
between medical … These adverse events occurred at
different centers and with
Different providers.