-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - • Few trials reported adverse events. … When reported,
adverse events often did not appear to be predefined,
were not systematically collected … events
data from different studies, adverse events reported
generally were consistent with known potential … CKD Treatment Harms
Knowledge Gaps
Withdrawals and adverse events were reported in few
RCTs. … Withdrawals often were not reported separately by
treatment group; adverse events often did not appear
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
January 01, 2025 - and
composite outcomes such as “sentinel events” or “adverse patient events.” … Preventable
adverse events decreased from 3.3 per 100 admissions to 1.5 per 100 admissions
(p=0.04) … Preventable adverse events decreased from 4.7
per 100 admissions to 3.3 per 100 admissions (p<0.001) … events per
1,000 hospital days:
Intervention: 60.4
Control: 60.4
Total adverse events per
1,000 … Study: new approach to handoffs slashes errors,
preventable adverse events; other medical
centers
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - events
IV. … events as in the total number of subjects that experienced an adverse event
b: English language abstracts … Predictors of pain relief and adverse events in
patients receiving opioids in a prehospital setting. … The effectiveness and adverse events of
morphine versus fentanyl on a physician-staffed helicopter. … Meta-analysis of rare binary events in treatment groups with unequal
variability.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-disposition-comments.pdf
September 18, 2024 - quality of life, as well as our secondary outcomes such as pain intensity, medication usage,
and adverse … events. … Several reviewers pointed out that adverse events (AE) are not a major concern with
behavioral treatments … noted that we discussed overall dropouts in the AE section, but such dropouts
may not actually be adverse … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - events,
and specific adverse events if data were available (e.g.,
injection-site reactions, infections … Compared with placebo,
leflunomide led to higher rates of withdrawals
because of adverse events, diarrhea … -
controlled trials, where adverse events were not
the primary outcome. … Overall adverse event
profiles appeared to be similar for biologic
DMARDs and placebo. … Information generally was insufficient for the comparative
harms, tolerability, adverse events, and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
September 30, 2015 - Eligibility Criteria Interventions Sample Characteristics Screened
Eligible
Randomized
Analyzed Results Adverse … Events and Withdrawals Due to Adverse Events Sponsor Quality
Hruschak, 2021 RCT
Duration: 6 weeks University … B (events/total person-years); adjusted Incidence Rate Ratio (aIRR):
Overdose: 3241/22097 vs. 11433/ … events identified from diagnosis codes Enrolled: 77,697
Analyzed: 77,697
Loss to followup: NA Sex, income … events using CPT and/or ICD codes Enrolled: 4,622
Analyzed: 4,622
Loss to followup: NA Race, sex, geographic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
June 29, 2019 - events in older adults are shown in green. … events, misuse, or opioid use disorder)? … b. reduce the risk of adverse events, misuse or opioid use disorder in older adults for
whom opioids … events. … Reducing the risk of adverse drug
events in older adults.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
February 17, 2016 - events? … events. … events due to mechanical devices (as reported by authors)
o Adverse events due to IVC filter (as … reported by authors)
o Other clinically significant adverse events reported by studies … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Number 17
Effective
Health Care
2
cancer by the Gail model or other criteria and low risk
for adverse … events. … Use of
medications to
reduce risk of
breast cancer
Adverse effects
of medications
1, 3, 4
Women … events and ≤4 percent for
nonprotocol-specified events … Further research to more clearly identify
characteristics of individuals experiencing specific
adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
June 01, 2022 - No serious adverse events, death,
or withdrawal due to adverse events were reported.
8
A subgroup … No serious adverse events or withdrawal due to adverse
events were reported. … No adverse events
were reported in either groups. … No
serious adverse events, death, and withdrawal due to
adverse events were reported. … No
significant adverse events were reported.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - ,
nausea, sedation) and study withdrawal due to adverse events. … events, and withdrawals due to adverse events for each included study. … a Other serious adverse events (i.e., psychosis and cannabis use disorder) not reported in any study. … ; VAS = visual analog scale; WAE = withdrawal due to due adverse events. … scale; WAE = withdrawal due to due
adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
November 01, 2014 - Rates of antibiotic-related adverse events?
Key Question 2. … Rates of antibiotic-related adverse events?
Key Question 3. … events, or infusion-related adverse effects. … reactions
1 RCT (n=20) Medium NA Unknown Imprecise
Insufficient
Adverse events
attributed to the … dosing regimen
of ceftazidime
1 RCT (n=24) Medium NA Unknown Imprecise
Insufficient
Adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
March 27, 2014 - In children with JIA, does the rate and type of adverse eventsf differ
between the various DMARDs or … How do the efficacy, effectiveness, safety, and adverse effects of
treatment with DMARDs differ among … with DMARDs, we focused primarily on serious infections and the development of cancer when assessing adverse … events. … Other adverse events considered included mortality, hepatitis, bone marrow suppression, nausea or vomiting
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
March 01, 2024 - • The identified diagnostic studies did not assess the adverse effects of being
labeled correctly … events … Furthermore, the identified studies did not assess the adverse effects of being labeled
correctly or … events, such as appetite suppression (RR 0.82; CI 0.53, 1.26, 8 studies, n=1463;
low SoE). … Across studies, medication therapy evaluations reported more adverse events
than non-medication interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
October 01, 2010 - of the various adverse events were not always
comparable." … Limitations of evaluation of adverse events have been added to
Discussion section. … Discussion Adverse effects: “There is a moderate level of evidence to show that
adverse events associated … These long-term
adverse events need to be explored in future studies. … types of adverse events were
different between groups, as would be expected.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
May 29, 2025 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
May 29, 2025 - The adverse events seen in the intervention groups would likely be lower than in the clinical setting … Thus, the occurrence of adverse events can be suppressed while adherence and benefits are accentuated … Run-in periods may suppress the occurrence of adverse events or accentuate the benefits, or both of these
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
September 01, 2016 - events by organ system.
2. … • Adverse event and deaths. … ClinicalTrials.gov began to mandate reporting of adverse
events in September 2009 as serious adverse … events and non-serious adverse events. … We
will compare the total adverse events reported in ClinicalTrials.gov compared with the
total reported
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
July 01, 2023 - patient and family perspectives can
be incorporated into patient safety, ultimately reducing risks for adverse … events and preventable
harms. … concurrent or historical
comparison group
• No clear description of
intervention
Outcome Safety
• Adverse … The missing evidence: a systematic review of patients' experiences
of adverse events in health care … Promoting engagement by patients and families to reduce adverse
events in acute care settings: a systematic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
April 01, 2014 - For Key Question 2 we considered the following
prespecified adverse events (harms): nausea; vomiting … severity of
patient-reported adverse events (nausea, vomiting,
fatigue, bloating, cramping, etc.). … Almost
universally, the rates of reported adverse events were
below 4 percent. … No studies reported
adverse events by any of the prespecified subgroups of
interest. … Hartmann's reversal is
associated with high postoperative adverse events.