-
effectivehealthcare.ahrq.gov/products/restless-legs/research
November 27, 2012 - assessed RLS symptom impact, sleep scale scores, disease-specific quality of life, withdrawals, and adverse … Dopamine agonists resulted in more patients who experienced at least one adverse event (high-strength … Treatment withdrawals were due to lack of efficacy (6% to 37%) as well as augmentation and other adverse … events. … Adverse effects of pharmacologic therapies and long-term treatment withdrawals due to adverse effects
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
January 01, 2013 - No
withdrawals due to adverse events or
other adverse events were observed. … events,
bleeding, renal dysfunction,
hepatotoxicity, and serious adverse
events. … events, renal
dysfunction, serious adverse events,
diarrhea, vomiting, nausea, adverse
events, hypercalcemia … No
withdrawals due to adverse events or other adverse events
were observed. … events, renal dysfunction, serious
adverse events, diarrhea, vomiting, nausea, adverse events,
hypercalcemia
-
effectivehealthcare.ahrq.gov/sites/default/files/s81.pdf
October 01, 2007 - ORIGINAL ARTICLE
Developing Indicators of Inpatient Adverse Drug Events
Through Nonlinear Analysis Using … The purpose of the study was rate estima-
tion for iatrogenic inpatient adverse events and validation … Up to 5 adverse events were
evaluated for each admission. … Medical Care • Volume 45, Number 10 Suppl 2, October 2007 Indicators for Adverse Drug Events
© 2007 … High rates of adverse drug
events in a highly computerized hospital.
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effectivehealthcare.ahrq.gov/products/colorectal-surgery-preparation/research-protocol
March 26, 2013 - diagnostic colonoscopy could provide additional data for some of the adverse events caused by OMBP, … What are the comparative adverse events of the various OMBP strategies? … potential adverse events? … events): Adults and children who undergo elective colon or rectal surgery
KQ 2b (adverse events, susceptible … Hartmann's reversal is associated with high postoperative adverse events.
-
effectivehealthcare.ahrq.gov/products/hepatitis-c/research
November 27, 2012 - Differences in harms were relatively small, with no difference in withdrawals due to adverse events, … therapy with pegylated interferon alfa-2b plus ribavirin was associated with a lower risk of serious adverse … events than dual therapy with pegylated interferon alfa-2a plus ribavirin. … Triple therapy with boceprevir was associated with increased risk of hematological adverse events, and
-
effectivehealthcare.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research
October 27, 2015 - Compared with no intravesical therapy, BCG was associated with a higher rate of local and systemic adverse … events (granulomatous cystitis or irritative symptoms in 27% to 84% of patients, macroscopic hematuria … Compared with MMC, BCG was also associated with an increased risk of local adverse events and fever ( … associated with decreased risk of bladder cancer progression, but it is associated with a high rate of adverse … events.
-
effectivehealthcare.ahrq.gov/products/skin-cancer/research
December 08, 2017 - Serious adverse events, events leading to treatment discontinuation, and treatment site infections were … recurrence, histologic clearance, clinical clearance, patient- or observer-rated cosmetic outcomes, adverse … Nearly all reported results for recurrence or cure rate outcomes and adverse events, and many reported
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plant-based-chronic-pain-review-q2.pdf
May 01, 2021 - events (WAEs), serious adverse events (SAEs), dizziness, nausea,
and sedation with oral plant-derived … Adverse events were poorly reported, with study
authors noting that no patients withdrew due to adverse … Other adverse events of interest were not reported. … adverse events. … controlled trial; SAE =
serious adverse event; WAE = withdrawal due to adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - Events and Withdrawals Due to Adverse Events Sponsor Quality
Hruschak, 2021 RCT
Duration: 6 weeks University … B (events/total person-years); adjusted Incidence Rate Ratio (aIRR):
Overdose: 3241/22097 vs. 11433/ … cardiovascular events (including ischemic heart disease, congestive heart failure, acute ischemic stroke … B
Major adverse cardiovascular events: 52 vs. 72
Incidence rate per 10,000 person months (95% CI): 30.12 … events identified from diagnosis codes Enrolled: 77,697
Analyzed: 77,697
Loss to followup: NA Sex, income
-
effectivehealthcare.ahrq.gov/sites/default/files/draft-appendixes-plant-based-treatment.pdf
March 01, 2021 - events and withdrawals due to adverse
events for each included study. … ; RCT = randomized controlled trial; RR = relative risk; WAE = withdrawal due to due adverse events … a Other serious adverse events (i.e., psychosis and cannabis use disorder) not reported in any study. … ; VAS = visual analog scale; WAE = withdrawal due to due adverse events
a Other serious adverse events … scale; WAE = withdrawal due to due adverse events
D-8
Appendix D-2.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
September 01, 2014 - We recommend that
the authors define what is meant by “Serious
Adverse Events”. … PG10: “Serious Adverse Events” are listed as
an outcome without definition. … PG37: Again, “Serious Adverse Events”
is undefined. … events or in the number of discontinuations due
to adverse events.” … “Renal-related Adverse Events” is a
more appropriate section header.
2.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plant-based-chronic-pain-review-q3.pdf
September 01, 2021 - There was no effect in pain interference or serious adverse events. … , nausea, sedation) and withdrawals
from studies due to adverse events. … events, and withdrawals due to adverse events for each included study. … ; VAS = visual analog scale; WAE = withdrawal due to due adverse events. … scale; WAE = withdrawal due to due
adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - Adverse events. … Adverse events, including serious adverse
events and grade 3-4 laboratory
abnormalities. … Adverse events. … Adverse events. … events, drug related adverse events, dose reductions
and discontinuations due to adverse events
Proportion
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
August 01, 2015 - The
present review assessed the comparative effectiveness and
adverse effects of 3DCRT, IMRT, SBRT, … This is a summary of a systematic review update evaluating recent evidence on the effectiveness and adverse … Summary of Key Findings and Strength of Evidence for the Benefits and Adverse Effects of Radiotherapy … events (e.g., dysphagia) and
improving quality of life
�– In understanding how outcomes are affected … events
information
�– Assessing quality of life and other patient-reported
outcomes with validated
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
March 26, 2013 - Because adverse events are commonly not well reported in surgical
trials, including studies of OMBP … What are the comparative adverse events of the various OMBP
strategies?
b. … potential adverse events? … diverticulitis vs. other)
• KQ 2a (adverse events): Adults and children who undergo elective colon … Hartmann's reversal is associated with high
postoperative adverse events.
-
effectivehealthcare.ahrq.gov/products/allergy-seasonal/research
July 16, 2013 - Structured Abstract
Objectives
This review compared the effectiveness and common adverse events of … Outcomes of interest were patient-reported symptom scores, quality of life, and adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
October 01, 2006 - Comparison of
adverse events and complications across the various
interventions is difficult. … Thirty-seven of these studies reported on
adverse events. … Adverse events (including 30-day mortality, Table B)
Adverse events were reported in 37 studies, including … Other adverse events reported
included hemorrhage and hematomas, and renal artery
occlusion. … Adverse events N/A • The evidence does not support meaningful conclusions about
relative adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - (Effect Size/SOE)a
Any time Insufficient evidence
No difference
+ No evidence
Harms/AEs – Adverse … Events or
Reactions Not Otherwise Specified
(Effect Size/SOE)a
Any time No evidence No difference … events; HDMF = higher total dose multiple fraction; HDSF = higher total dose single fraction; LDMF = … events; EBRT = external beam radiation
therapy; IMRT = intensity modulated radiation therapy; MBD = … There may be no differences in pain
response or serious adverse events between concomitant use of EBRT
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Number 17
Effective
Health Care
2
cancer by the Gail model or other criteria and low risk
for adverse … events. … Use of
medications to
reduce risk of
breast cancer
Adverse effects
of medications
1, 3, 4
Women … events and ≤4 percent for
nonprotocol-specified events … Further research to more clearly identify
characteristics of individuals experiencing specific
adverse
-
effectivehealthcare.ahrq.gov/products/dietary-supplements/research
April 30, 2012 - This also poses risks of adverse events from supplement-drug interactions and nonadherence associated … was insufficient for all gradable clinical efficacy and harms outcomes (e.g., mortality, thrombotic events … , serious adverse events) because there were few, small studies per supplement.