-
effectivehealthcare.ahrq.gov/products/musculoskeletal-disorders-imaging/research-protocol
August 05, 2010 - test in patient management
Setting where positional MRI testing was performed
Outcomes assessed
Adverse … events, harms and safety issues reported
Comparators used (applicable only to comparative studies)
-
effectivehealthcare.ahrq.gov/products/insomnia/research-protocol
April 03, 2014 - Sickness Impact Profile Scale 28 ; World Health Organization Quality of Life (WHOQOL) 28 ]
KQ2
Adverse … effects of intervention(s)
Any serious adverse effects (e.g., dependence, falls, abnormal sleep behaviors … Figure 1 provides an analytic framework to illustrate the population, interventions, outcomes, and adverse … insomnia definition, method of diagnosis, and severity, descriptions and results of primary outcomes and adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - nonpharmacologic treatments13 have small to moderate effects on pain and function, with
some frequent adverse … Similarly, it is
important to identify harms and adverse effects of PBCs. … that are similar to opioids in effect and that
have the potential for addiction, misuse, and serious adverse … All KQs: Primary efficacy outcomes (i.e.,
pain, function, disability, pain interference);
harms and adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
May 01, 2013 - There
are significant adverse consequences of
DVT and PE,1 including an estimated
300,000 fatalities … populations of interest, therapies, and intermediate and
clinical outcomes we reviewed, as well as the adverse … Outcomes
• Asymptomatic deep
vein thrombosis
• INR, PTT, Serum
Factor Xa level )
KQs 6, 7, and 8)
Adverse … Heparin-induced
thrombocytopenia
• Allergic reaction
• Mechanical device
complications
• Infections
Adverse … Enoxaparin dose adjustment is
associated with low incidence of venous thromboembolic events in
acute
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
May 14, 2019 - together in the data abstraction
to reflect the many ways individual studies
discussed outcomes and adverse … events
related to suicide. … together in the data abstraction to reflect the
many ways individual studies discussed
outcomes and adverse … events related to
suicide. … Peer Reviewer #4 Appendix Table 5-10: Having multiple different adverse events clustered in
a single
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
June 01, 2018 - stage and sex group.5 The
reference value that represents an intake above which the
risk of potential adverse … DRI reports) and (3)
the level of sodium intake that had shown an association
in some studies with adverse … outcomes, were not powered to assess them
as prespecified outcomes, and reported them instead as
adverse … events … Effect of reduced sodium intake on blood pressure, renal function,
blood lipids and other potential adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/searching.ppt
January 01, 2011 - international in scope)
PsychLit/PsychINFO (Psychology)
AIDSLine (HIV/AIDS)
CINAHL (Nursing)
TOXNET (Adverse … Events/Toxicology)
Generally, a minimum requirement for a thorough search of literature
Relevo R, … events and toxicology. … Harms Searching
If the specific adverse effects of interest are specified in the key questions, they … General harms subheadings for MEDLINE would include:
/adverse effects
/poisoning
/toxicity
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
August 10, 2022 - Debilitating skeletal-related events (SREs) such as
pathological fractures, metastatic spinal cord compression … re-radiation
• Use of pain medication, need for other
interventions for pain relief
Harms and adverse … events
Harms (e.g., rate of radiation/treatment toxicity,
radiation-induced fracture rates, reduced … mobility,
reduced independence), adverse events (pain flare,
radiation recall, fatigue, skin changes … This may be based on sample size sufficiency and number of
events.
-
effectivehealthcare.ahrq.gov/products/ankyloglossia/research-protocol
June 30, 2014 - breastfeeding, sucking, weight gain) all improved post-procedure, and no studies reported significant adverse … OR “risk”[tiab] OR “risks”[tiab] OR “side-effect”[tiab] OR “side-effects” [tiab]OR ((undesirable OR adverse … ) AND (effect OR effects OR reaction OR reactions OR event OR events OR outcome OR outcomes))OR” sequelae … postoperative OR surgical OR “post operative” OR “post surgical”) AND (complication OR complications)) OR “adverse
-
effectivehealthcare.ahrq.gov/system/files/docs/headaches-pregnancy-topic-brief.pdf
January 01, 2019 - No evidence of adverse pregnancy outcome after
exposure to ibuprofen in the first trimester - Evaluation … Ondansetron in pregnancy and risk of adverse fetal
outcomes in the United States. … Increased risk of adverse pregnancy outcomes for
women with migraines: a nationwide population-based … Migraine with aura and
reproductive life events: a case control study. … Migraine without
aura and reproductive life events: a clinical epidemiological study in 1300 women.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-protocol.pdf
July 01, 2023 - infection (CLABSI), catheter-associated
urinary tract infection (CAUTI), ventilator associated pneumonia/events … Cost
• Unintended effects
o Patient mental health/social
isolation/satisfaction
o Noninfectious adverse … CLABSI)
o Catheter-associated urinary tract
infection (CAUTI)
o Ventilator-associated pneumonia or
events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
January 01, 2020 - The authors should bring the issue of changing the definition
of 'mild GDM' as a 'risk factor' of adverse … I looked at the data from the
paper and it appears that the number of events
(macrosomia >4000 gms) … Therefore, for figure 25 events should be 25 instead of
148 for GDMs and 905 instead of 6695 for No … This is a
very important suggestion as maternal BMI/weight gain are
more/equally important for adverse … Research indicates
that IGT and GDM carry similar risks of adverse outcomes.
-
effectivehealthcare.ahrq.gov/products/back-pain-treatment/research-protocol
October 08, 2014 - U.S. adults report recent (in the last three months) low back pain. 1,2 Low back pain can have major adverse … Global improvement
Number of back pain episodes or time between episodes
Patient satisfaction
Adverse … Analytic Framework
The analytic framework illustrates the population, interventions, outcomes, and adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - low-value services, bundled payment could lead to underuse of appropriate
services, with potential adverse … effects on the
risk profiles of treated patient populations, since risk selection is a potential
adverse … Studies may report on this as a
measure of a potential adverse effect of bundled payment on risk selection
-
effectivehealthcare.ahrq.gov/sites/default/files/innovations_in_stakeholder_engagement_conference_summary2.pdf
October 01, 2011 - • Prediction markets allow users to forecast outcomes of future events and provide a
space for users … health can be used, for example, to estimate future demand for a particular
treatment or forecast events … Accountability Act
(HIPAA) and Stark regulations for hospitals and issues related to off-label use and adverse … events of medications, as well as discoverability, privacy and confidentiality. … Examples include
community events (e.g., town hall meetings, health fairs), involving the local press
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - life; they may also involve known or potential harms, such as occurrences of serious and
troubling adverse … events and inconveniences. … Low
(decreased
cholesterol
by 2.1%)
Radiology test RCT: 0 No eligible studies Insufficient
Adverse … table outcomes into the following main categories:
major, other patient-centered, intermediate, and adverse … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - testing
Treatment Options
See Tables A -C for possible interventions and comparisons
Adverse … Adverse Events
The six studies that reported on adverse events did not find
substantial differences … For none of the advanced wound dressings was there a
systematic assessment of harms or adverse events … This substantially differs
from the studies of regulated pharmaceuticals, which
carefully record adverse … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - 2b: In patients with a renal mass suspicious for stage I or II renal cell carcinoma,
what are the adverse … o Diagnostic test-related outcomes
o False positives
o False negatives
o Radiation exposure
o Adverse … effects of percutaneous renal mass sampling:
o Pain
o Hemorrhage
o Tumor Seeding
o Adverse effects … Diagnostic Test-Related Outcomes:
• False positives
• False negatives
• Radiation exposure
Adverse … kidney disease
o Incidence of end-stage renal disease
• Overall survival
• Quality of Life
Adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
March 16, 2017 - ambulation
o Other patient-centered ambulatory function measures
o Exclude biomechanical measures
• Adverse … Outcomes
• Functional, patient-centered, and ambulatory outcomes per KQ 4
• (Not adverse … 4; characteristics)
Final Outcomes
(KQ 3, 4, 5. 6, 7; characteristics)
KQ 3, 4, 5:
KQ 4:
Adverse … events §
KQ 6:
Satisfaction
KQ 7:
Bipedal ambulation
Prostheis use only for transfers
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/1-for-children-with-disruptive-behavior-disorders-dbds-including-oppositional-defiant-disorder-odd-conduct-disorder-cd-and-disruptive-behavior-disorder-not-otherwise-specified-dbd-nos-what-is-the-short-term-and-long-term-comp
March 19, 2013 - pharmacological treatments, including relative decrease in treatment adherence and withdrawal due to adverse … events
Impaired growth and maturation
Self-injury and suicide-related behaviors
Increased disruptive