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1261. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
      July 01, 2012 - identify the included patients.20 Thus, when comparing various tests for diagnosing acute coronary events … falsely positive would receive no benefit but will still be exposed to the risk of treatment-related adverse … inhibitors (the treatment available at the time of the evidence report) The framework assumes no major adverse … report, the then-available treatment options (acetylcholinesterase inhibitors) do not have important adverse

1262. Wireless-Motility-Capsule Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
      May 01, 2013 - ROM† Harms Low 5 Harms and adverse events were infrequently reported for WMC or ROM. … One of the studies reported few events, providing imprecise results. … events for WMC or ROM. … WMC is comparable to ROM with regard to low frequency of harms, as no studies reported serious adverse … events or mortality.

1263. Disposition of Comments Report for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
      January 01, 2010 - Earlier in document refer repeatedly to “adverse effects” – change here to adverse effects instead of … “harms” Revised and have replaced harms with adverse effects throughout the report. … Maternal fever, nausea, and vomiting are not a list of anesthesia-related events. … “adverse effects” Have revised throughout the report. … We then systematically reviewed each included study for adverse effects.

1264. Making Healthcare Safer IV: Supply Chain Disruption Monitoring Programs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
      January 01, 2024 - Disruptions can occur due to myriad reasons ranging from the scarcity of raw materials,4 unforeseen events … delays in care which can result in sourcing inferior or illegitimate products,10 increased risk of adverse … events, and increased costs.

1265. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
      July 01, 2023 - safety, increase reporting of outcomes, or offer feedback to institutions to reduce patient safety events … assessing data quality of a report card) • No clear description of comparator Outcome Safety • Adverse … events Quality of care measures (including morbidity and mortality) Implementation • Barriers

1266. Title (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
      March 31, 2010 - Obese children and adolescents are more likely to have adverse health conditions, such as cardiovascular … purchasing behaviors o dietary intake o food access o physical activity o sedentary behavior  Adverse … Analytic Framework for Comparative Effectiveness of Childhood Obesity Intervention Programs Adverse … Psychosocial outcomes, e.g., stigma  Impact on growth and development  Injury  Cost  Other adverse … is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse

1267. Bladder-Cancer-Non-Muscle-Invasive Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
      July 21, 2014 - Key Question 7: What are the comparative adverse effects of various tests for diagnosis Source: www.effectivehealthcare.ahrq.gov … Key Question 8: What are the comparative adverse effects of various treatments for non- muscle-invasive … a) How do adverse effects of treatment vary by patient characteristics, such as age, sex, ethnicity … 3, KQ 4, KQ 5: Progression of cancer • For KQ 2, KQ 3, KQ 4, KQ 5: Quality of life • For KQ 7: Adverse … diagnostic testing (e.g., false-positives, labeling, anxiety, complications of cystoscopy) • For KQ 8: Adverse

1268. Simulation-Based Comparison of Methods and Meta-Analysis of Proportions and Rates (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/metanalysis-proportion-rate-comparison_research.pdf
      November 01, 2013 - perform meta- analyses of sensitivity and specificity to summarize medical test performance, or of adverse … or harmful events. … For example, one would use a meta-analysis of proportions to calculate the summary frequency of adverse … or harmful events. … Depending on the clinical context, adverse events can be rare (e.g., the incidence rate of rhabdomyolysis

1269. Disposition of Comments: CER 227 Noninvasive Nonpharmacological Treatment for Chronic Pain (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
      April 16, 2020 - although effect sizes are moderate, we believe it is important to acknowledge that there were no adverse … events associated with non- pharmacological interventions. … The report describes the harms and adverse events that were reported. … Nonpharmacological Treatment of Army Service Members with Chronic Pain Is Associated with Fewer Adverse … for reporting adverse reactions.

1270. Gout-managment-protocol-141103 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol.pdf
      November 03, 2014 - Outcomes for acute gout management will include short-term pain, joint swelling and tenderness, and adverse … events (AEs); and longer term control of serum UA concentrations, pain, joint swelling and tenderness … Observational studies will be included for the assessment of rare adverse events.

1271. Phenylketonuria Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
      February 01, 2012 - Individuals with PKU are also suscep- tible to other adverse outcomes, includ- ing impaired executive … What are the harms, including adverse events, associated with the use of BH4 or LNAAs in individuals … phenylketonuria * Encompasses a full range of specific negative effects, including the narrower definition of adverse … events. … In addition to outcomes for treatment effect, we extracted data on harms/adverse effects.

1272. Closing the Quality Gap Series: The Effects of Bundled Payment Strategies on Health Care Spending and Quality of Care | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/bundled-payments-quality-effects/research-protocol
      June 23, 2011 - low-value services, bundled payment could lead to underuse of appropriate services, with potential adverse … on effects on the risk profiles of treated patient populations, since risk selection is a potential adverse … Studies may report on this as a measure of a potential adverse effect of bundled payment on risk selection

1273. Chronic-urinary-retention-protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research-protocol.pdf
      November 19, 2012 - or symptom or QoL scores (KQ 2) surgical interventions ·∙ Kidney failure (KQ 1a) ·∙ Adverse … (KQ 1 a) treatment (KQ2a) Effect Modifiers ·∙ Treatment discontinuation due ·∙ Age to adverse … diagnosis, CUR etiology and severity; descriptions and results of clinical and intermediate outcomes and adverse

1274. Methods Guide Atkins (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
      January 01, 2011 - For example, evidence of the benefits of aspirin for prevention of cardiovascular events from patients … A more common source for heterogeneity in treatment effect is varying baseline rates of events. … For example, although statins reduce risks of fatal and nonfatal coronary events comparably in populations … experience of the participating centers and surgeons may influence both the effectiveness of treatment and adverse

1275. Methods-Guidance-Applicability Methods (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
      January 01, 2011 - For example, evidence of the benefits of aspirin for prevention of cardiovascular events from patients … A more common source for heterogeneity in treatment effect is varying baseline rates of events. … For example, although statins reduce risks of fatal and nonfatal coronary events comparably in populations … experience of the participating centers and surgeons may influence both the effectiveness of treatment and adverse

1276. Disposition of Comments Report for Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
      June 07, 2013 - OCs and Vascular Events (pg. 177) Page 211 - lines43 and 44. … OCs and Vascular Events (pg. 190) Page 224. lines 54-57. … OCs and Vascular Events (pg. 191) Page 225. Lines24 to 25. … willingness-to-pay’ (WTP) in terms of harms incurred versus benefits gained; in other words, the sum of all adverse … Similar descriptions should be given for “vascular” events.

1277. Research Protocol: Diabetes Medications for Adults With Type 2 Diabetes: An Update Focused on Monotherapy and Add-On Therapy to Metformin (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
      January 01, 2015 - effectiveness at reducing hemoglobin A1c (HbA1c) and their propensities to cause side effects and serious adverse … events; and not all are approved for monotherapy. … Additionally, we will grade the strength of evidence for adverse events that are most relevant for a

1278. Amended Protocol: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
      February 25, 2021 - What adverse events or unintended consequences are associated with provider-to-provider telehealth … similar or more advanced health care systems and resources Mass casualty and war/battlefield events … What adverse events or unintended consequences are associated with provider-to-provider telehealth

1279. Traumatic Brain Injury and Depression (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
      January 30, 2014 - in"genes"associated"with"serotonin"transport"and" metabolism"predicted"greater"response"to"treatment"and"occurrence"of"adverse"events … $Scores$on$the$Rosenberg$ Self"Esteem$scale$also$improved,$and$the$ exercise$had$no$adverse$effects … Anxiety$Inventory),$perceived$social$support$(Interpersonal$Support$Evaluation$List),$stressful$life$events … or$baseline$measures$of$depression,$anxiety,$participation,$perceived$social$support,$stressful$life$events … $Scores$ on$the$Rosenberg$Self" Esteem$scale$also$ improved,$and$the$exercise$ had$no$adverse$effects

1280. FRN 22: Future Research Needs for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
      January 01, 2020 - What are the nature and frequency of adverse effects resulting from strategies used to reduce cesarean … Key Question 4 seeks to identify any adverse effects resulting from the use of strategies to reduce … It shows how adverse events may occur at any point after the strategy has been implemented. … delivery room; Special care nursery admission (anything more than well-baby nursery); Seizure; ST events … Events Study Title: High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour Condition