-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
April 01, 2013 - to adverse effects. … , intervention-group rates of events, or both. … • Health-related quality of life and serious adverse events
were inconsistently reported in the seven … For adverse effects, we considered
discontinuation due to adverse effects and worsening of
psychiatric … , and
adverse events
Improved reporting of efficacy–effectiveness
characteristics
CATIE = Clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol.pdf
May 20, 2024 - outcomes, parent/caregiver
outcomes
5
Inclusion Criteria Exclusion Criteria
• Any reported adverse … events or unintended negative
consequences attributed to treatment
Additional outcomes (children … :
• Quality of life
• General and social functioning
• Disability
• Depression
• Anxiety
• Adverse … events
We will grade the SOE based on the recommendations given in the EPC Methods Guide.42 The … intervals relative to a clinically important effect
estimate, sufficiency of sample size, and number of events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
January 01, 2023 - reliability; they anticipate, early
detect, and respond to unsafe conditions before they result in adverse … events.4
Respectful interaction and heedful interrelating are critical elements, as they foster trust
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
December 09, 2009 - Objectives for the Systematic Review
Traumatic brain injury (TBI) occurs when external force from events … Framework
Provide an analytic framework to illustrate the population, interventions, outcomes, and adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-update_research-protocol.pdf
June 15, 2016 - global assessment, patient satisfaction)
§ Surgery (i.e., rate of undergoing knee replacement)
o Adverse … We will include prospective
observational studies and case reports that report on adverse events … events, we will use the McHarms scale for
each study. … Adverse events identified in RCTs will be pooled if their numbers are reported separately by
treatment … Adverse events reported in single arm trials and observational studies will be
tabulated and reported
-
effectivehealthcare.ahrq.gov/products/asthma-nitric-oxide/research-protocol
September 12, 2016 - children ages 5 and above
Negative predictive for children ages 5 and above
KQ1a-e:
Any reported adverse … children ages 5 and above
Negative predictive for children ages 5 and above
KQ 1a-e:
Any reported adverse … of the studies (i.e., risk of bias); precision (based on the size of the body of evidence, number of events … NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response
-
effectivehealthcare.ahrq.gov/products/gout/research-protocol
November 03, 2014 - Outcomes for acute gout management will include short-term pain, joint swelling and tenderness, and adverse … events (AEs); and longer term control of serum UA concentrations, pain, joint swelling and tenderness … Observational studies will be included for the assessment of rare adverse events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
May 26, 2015 - Health and safety outcomes (e.g., cardiovascular events or incidence of work-
related injuries)
Source … o KQ 2d: Harms: Increased barriers to reporting work-related injuries or
illnesses, work stress, adverse … Framework
The analytic framework in Figure 1 illustrates the population, interventions, outcomes,
and adverse … Initiatives, National
Institutes of Health 2015 February 26, 2015. https://prevention.nih.gov/programs-
events
-
effectivehealthcare.ahrq.gov/sites/default/files/s166.pdf
October 01, 2007 - wakefulness after
sleep onset (WASO), sleep efficiency (SE), total sleep time
(TST), sleep quality (SQ), and adverse … events (AE). … Adverse Events
The AE estimates were similar across comparisons,
ranging from risk differences of 0.07
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nitric-oxide_research-protocol.pdf
September 06, 2016 - ages 5 and above
• Negative predictive for children ages 5 and above
KQ1 a-e:
• Any reported adverse … ages 5 and above
• Negative predictive for
children ages 5 and above
KQ1 a-e:
• Any reported adverse … the studies (i.e., risk of bias); precision (based on the size of the body of evidence,
number of events … NO chemical events in the human
airway during the immediate and late antigen-induced asthmatic response
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
April 22, 2013 - Rare but serious adverse events are rarely captured
by RCTs.
1) We excluded very small studies (n< … Further, adverse effects of antipsychotic drugs
have been thoroughly summarized in existing
systematic … Conclusion Further, it is noted throughout the review that
intervention effects on overall CVD risk, CVD events … We have modified one gap to include better
reporting of adverse events and added an
additional research … Not all outcomes are explicitly listed in the KQs;
however, adverse effects and other outcomes
are
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
September 13, 2013 - stratify the findings of the previous
review, as well as any newly included studies on efficacy and adverse … or symptoms
Cerebrovascular events
Peripheral vascular events or symptoms
Cardiovascular death … strength
Source: www.effectivehealthcare.ahrq.gov
Published online: June 10, 2013
4
o Adverse … mortality
Cancer and cancer-specific mortality
Renal outcomes
Soft tissue calcification
(Other) adverse … For upper limit
(adverse event [AE]) outcomes, we will include any adverse effects of high intake in
-
effectivehealthcare.ahrq.gov/products/rural-telehealth/protocol
January 15, 2021 - What adverse events or unintended consequences are associated with provider-to-provider telehealth for … similar or more advanced health care systems and resources
Mass casualty and war/battlefield events … What adverse events or unintended consequences are associated with provider-to-provider telehealth for
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd4-update-draft-report.pdf
October 01, 2022 - events, serious adverse events
• Timing:
o No limitation on study duration or length of followup … In some
instances, distinguishing harms from negative outcomes (e.g., unintended adverse consequences … Many studies of both pharmacologic and nonpharmacologic
interventions did not report details about adverse … events. … Posttraumatic Stress Disorder
NET Narrative Exposure Therapy
NR not reported
NSESSS National Stressful Events
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - Mitigation of long-term adverse effects by changes in regimen, including reduced-intensity
approaches … But, it is well recognized that regimens vary in their
potential for long-term adverse effects. … Patients
will need to be
followed for at least
5 years for enough
events to occur to
enable a
comparison … Patients will
need to be followed for
at least 5 years for
enough events to occur
to enable a comparison … Events
This study
is ongoing,
but not
recruiting
participants.
-
effectivehealthcare.ahrq.gov/products/erythropoiesis-stimulating-agents-utilization/research
March 31, 2011 - to 12 grams per dL.5 A number of published studies, beginning in the late 1990s, suggested potential adverse … beneficiaries with kidney disease (KD) and to relate these trends to the timing of clinical practice and policy events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - • No adverse events, except for a few cases of nausea,
were reported in the trial evaluating bupropion … Risk of withdrawal due to adverse events
appeared to differ between dopamine agonists (I2=73%,
p=0.02 … events were reported. … events, and augmentation). … About half of withdrawals were due to adverse events,
including augmentation; 20 percent to 30 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - is the comparative effectiveness of aspirin
and other antiplatelet agents in reducing the
risk of adverse … What are the significant safety concerns associated
with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated
with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated
with each treatment strategy (e.g., adverse
drug … Some RCTs
reported adverse events such as rash and wound leak.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - events
associated with this therapy.†
* Also see: Witter … While we
agree there might be benefits to investigating serious and rare adverse events in an
hypothesis … events
Maternal side effects (pulmonary edema, heart failure, arrhythmia,
myocardial infarction, … Further, data will be extracted as number of patients with an event (as opposed to
number of events) … For rare outcomes,
only studies with events recorded will be included in combined estimates.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
March 01, 2012 - or instruments used to capture all possible adverse events
can be problematic. … with adverse events; however, these criteria are applicable to other interventions,
although no formal … that allow for
reproducible ascertainment (what adverse events were being
investigated and what constituted … Were SERIOUS events precisely defined?
3. Were SEVERE events precisely defined?
4. … Adverse
effects. In: Higgins JPT, Green S, eds.