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Showing results for "adverse events".
Users also searched for: patient safety indicators

1201. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
      January 01, 2012 - reactive LGS), or the monitor can use control algorithms to predict and prevent potential hypoglycemic events … results showing use of these systems will “prevent or reduce the length and severity of hypoglycemia events … Transient and predominantly mild to moderate nausea, the most frequent adverse event, was less … No major hypoglycemia events occurred. 47 In July 2011, Amylin Pharmaceuticals, Eli Lilly, and … events (i.e., cardiac abnormalities, carcinomas), patient adherence to treatment recommendations and

1202. Treatment of Stages I-III Squamous Cell Anal Cancer: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/anal-cancer-draft-report.pdf
      October 31, 2023 - RT alone, frequency: 1vs.0 grade 4 events (n=110); or 20 vs.0 overall events (n=585). … , clinical characteristics including cancer stage and outcome timing, and results of outcomes and adverse … and grade 4 toxicity frequency of 12 events with MMC vs. 8 events with cisplatin. … arm and grade 4 toxicity frequency of 11 events in MMC arm vs. 0 events in cisplatin arm. … as persistently poor quality of life, pain, and worsening bowel and sexual function are potential adverse

1203. Breast Reconstruction After Mastectomy | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/breast-reconstruction-mastectomy/protocol
      June 18, 2020 - delays in other cancer-related treatments (e.g., chemotherapy, radiation therapy)* Thromboembolic events … delays in other cancer-related treatments (e.g., chemotherapy, radiation therapy)* Thromboembolic events … delays in other cancer-related treatments (e.g., chemotherapy, radiation therapy)* Thromboembolic events … OR "Tissue Transplantation"[Mesh] OR ((flap OR flaps) AND (surgical OR surgery))) AND (safe* or adverse … or risk or risks or reaction* or complication* or poison* OR side effect* or safety or unsafe OR ((adverse

1204. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
      January 01, 2012 - experienced an average reduction of the Clinical Colitis Activity Index to 57% of baseline, and no adverse … events were seen during the 28-week followup period, the authors reported. 9 In a larger study of … events. … Some experts were also unsure if reductions in PN would be enough to outweigh adverse events observed … events contrasted against the modest reductions in PN.

1205. Depression-Chronic-Conditions-Interventions Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-chronic-conditions-interventions_executive.pdf
      August 01, 2012 - the TEAMcare study, involving patients with depression, diabetes, and/or heart disease,68 defined adverse … events; the investigators reported higher rates of mild adverse events (e.g., medication side effects … ) and of moderate adverse events (e.g., falls) in the intervention arm. … intervention arm had more frequent contacts with the care manager and thus had more opportunities to report adverse … events, so findings might be the result of detection bias.

1206. Observational Studies: Empirical Evidence of Their Contributions to Comparative Effectiveness Reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-studies_white-paper.pdf
      December 01, 2013 - events). … events (n=4), a limited number of trials (n=1), and to target special populations that are typically … Modified AHRQ methods guide Narrative description SOE method unclear Yes Notes: AEs = adverse … events; CAM = complementary and alternative medicine; CC = case control; CER = comparative effectiveness … □ NA Include: □ Long-term follow-up □ Safety / adverse event outcomes □ Limited trials

1207. Pressure Ulcer Treatment Strategies: A Comparative Effectiveness Review | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/pressure-ulcer-treatment/research-protocol
      November 08, 2011 - Our review will include an assessment of adverse effects or harms associated with pressure ulcer treatment … treating a pressure ulcer against another provide direct evidence of comparative effectiveness and adverse

1208. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
      January 01, 2012 - events remain low. … surgical intervention, when compared with current surgical management, and concerns over potential adverse … events associated with in utero surgery for repair of myelomeningocele. … Based on potential reduction in VP shunt malfunction, reduction in adverse events, and improvement … events.

1209. Use of Electronic Medical Records and Administrative Claims Data for Assessing Type 2 Diabetes Care | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/diabetes-claims-data/research
      April 07, 2010 - For the clinical goal of assessing medication use in DMT2 patients, we focused on patients with adverse … DMT2 NC Medicaid patients, we identified 49 who had an MI, 173 who had a stroke, and 14 who had both events … extraction of clinically relevant text data regarding historical notations, negation, diagnostic issues, and adverse … With regard to the clinical goal of this project, patients who suffered adverse outcomes (MI, stroke, … These patients had relatively high utilization of care in the year before the adverse outcome, suggesting

1210. Diabetes-Drugs-Utilization Research (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-drugs-utilization_research.pdf
      March 01, 2011 - rosiglitazone, a thiazolidine- dione, was found to be associated with myocardial infarction, major adverse … cardiovascular events, mortality from cardiovascular causes, and all-cause mortality.8 A more recent … and pioglitazone uti- lization from January 2007 through May 2008 associated with five risk-warning events

1211. Medication-Therapy-Management Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
      November 01, 2014 - adverse drug events, many patients do not receive optimal pharmaceutical prescriptions. … drug events. … drug events or mortality (Table D). … drug events, prescriber confusion, and prescriber dissatisfaction. … events.

1212. Comparative Effectiveness of Strategies to De-escalate Aggressive Behavior in Psychiatric Patients in Acute Care Settings (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
      October 01, 2016 - One RCT43 examined three possible harms: drug-related adverse effects; incidence of abnormal QT (QRS … flunitrazepam, no statistical testing reported (3 vs. 3, p=NR).48 Drug-related adverse events 91 … Few overall treatment-emergent adverse events with olanzapine vs. risperidone vs. haloperidol, p … =NR.72 Adverse events considered related to primary antipsychotic medication 558 Insufficient … No significant difference in discontinuation due to clinically significant adverse events with olanzapine

1213. Mental-Illness-Heart Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
      April 01, 2013 - to adverse effects. … , intervention-group rates of events, or both. … • Health-related quality of life and serious adverse events were inconsistently reported in the seven … For adverse effects, we considered discontinuation due to adverse effects and worsening of psychiatric … , and adverse events Improved reporting of efficacy–effectiveness characteristics CATIE = Clinical

1214. Vitamin-D-Calcium-Protocol-130611 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/vitamin-d-calcium_research-protocol.pdf
      September 13, 2013 - stratify the findings of the previous review, as well as any newly included studies on efficacy and adverse … or symptoms  Cerebrovascular events  Peripheral vascular events or symptoms  Cardiovascular death … strength Source: www.effectivehealthcare.ahrq.gov Published online: June 10, 2013 4 o Adverse … mortality  Cancer and cancer-specific mortality  Renal outcomes  Soft tissue calcification  (Other) adverse … For upper limit (adverse event [AE]) outcomes, we will include any adverse effects of high intake in

1215. Future Research Needs for Hematopoietic Stem-Cell Transplantation in the Pediatric Population (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
      February 01, 2012 - Mitigation of long-term adverse effects by changes in regimen, including reduced-intensity approaches … But, it is well recognized that regimens vary in their potential for long-term adverse effects. … Patients will need to be followed for at least 5 years for enough events to occur to enable a comparison … Patients will need to be followed for at least 5 years for enough events to occur to enable a comparison … Events This study is ongoing, but not recruiting participants.

1216. Data Points #4: Trends in the utilization of erythropoiesis-stimulating agents among Medicare beneficiaries with kidney disease | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/erythropoiesis-stimulating-agents-utilization/research
      March 31, 2011 - to 12 grams per dL.5 A number of published studies, beginning in the late 1990s, suggested potential adverse … beneficiaries with kidney disease (KD) and to relate these trends to the timing of clinical practice and policy events

1217. Restless-Legs Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
      November 01, 2012 - • No adverse events, except for a few cases of nausea, were reported in the trial evaluating bupropion … Risk of withdrawal due to adverse events appeared to differ between dopamine agonists (I2=73%, p=0.02 … events were reported. … events, and augmentation). … About half of withdrawals were due to adverse events, including augmentation; 20 percent to 30 percent

1218. Peripheral-Artery-Disease-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
      May 01, 2013 - is the comparative effectiveness of aspirin and other antiplatelet agents in reducing the risk of adverse … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … What are the significant safety concerns associated with each treatment strategy (e.g., adverse drug … Some RCTs reported adverse events such as rash and wound leak.

1219. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
      October 18, 2010 - events associated with this therapy.† * Also see: Witter … While we agree there might be benefits to investigating serious and rare adverse events in an hypothesis … events Maternal side effects (pulmonary edema, heart failure, arrhythmia, myocardial infarction, … Further, data will be extracted as number of patients with an event (as opposed to number of events) … For rare outcomes, only studies with events recorded will be included in combined estimates.

1220. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
      March 01, 2012 - or instruments used to capture all possible adverse events can be problematic. … with adverse events; however, these criteria are applicable to other interventions, although no formal … that allow for reproducible ascertainment (what adverse events were being investigated and what constituted … Were SERIOUS events precisely defined? 3. Were SEVERE events precisely defined? 4. … Adverse effects. In: Higgins JPT, Green S, eds.