-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
February 22, 2012 - Quality of life
o Adverse effects
1. Worsening of tinnitus
2. Sedation
3. … Return to “normal” work
o Adverse effects
1. Worsening of tinnitus
2. Sedation
3. … Depression
Sleep disturbances
Self-reported loudness
Quality of life
Time until improvement
Adverse … In addition to
outcomes related to treatment effectiveness, all available data on harms or adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
May 12, 2015 - .
§ Common adverse effects of many antipsychotics used for schizophrenia include: weight gain, diabetes … disorder, with a focus on core illness symptoms, functional outcomes, health care system utilization,
and adverse … events.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - Settings
Clinical settings Clinical settings General and clinical settings Clinical settings
Adverse … Adverse events (AE) may occur at any point after the meditation program. … We will model
rare adverse events (<1%) using the Peto Odds ratio approach which has the best confidence … We will model rare
adverse events (<1%) using the Peto
Odds ratio approach which has the
best confidence … Adverse events (AE)
may occur at any point after the meditation program.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
September 01, 2011 - Of these, at least
three maternal deaths and three cardiovascular adverse
events were clearly reported … However, given the small number of
events and limited sample size (n=42), the RCT was
underpowered and … events—the
rarer the adverse event, the stronger is the effect size,
and the magnitude of effect size … is an important criterion
that increases our confidence in an estimate.9 However,
adverse events such … events in the
absence of terbutaline therapy due to other reasons.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
August 01, 2012 - consequences of an intervention,
including adverse events (Figure A).14
Key Questions
We have synthesized … events in ASD without being limited to a specific age
range. … events be listed for a drug, rather than just
those for a particular indication. … events may be associated with
medication use in adolescence. … The effects of a rotating
classroom schedule on classroom crisis events in a school for
autism.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - review, as well as demographic and
other data needed for determining outcomes (intermediate, final, and adverse … events outcomes). … The safety outcomes will be framed to help
identify adverse events, including those from drug therapies … study design; patient
characteristics; clinical settings; interventions; and intermediate, final, and adverse … , intervention group rates of events, or both.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-child-interventions_research-protocol.pdf
March 26, 2012 - with a physical illness, 11%; serious accident, 11.6%; natural disaster, 11.1%; fire,
5.9%).1 The Adverse … of childhood trauma
exposure in a large adult population.4 In this population, 65 percent recalled adverse … The criteria for DTD include exposure to
multiple or prolonged adverse events and experiences of affective … Traumatic events and posttraumatic stress in
childhood. … household dysfunction, and the risk
of attempted suicide throughout the life span: findings from the Adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
December 31, 2017 - are more effective for victims of particular types of
trauma or to determine comparative risks of adverse … KQ 4: What adverse events (AEs) are associated with treatments for adults diagnosed with
PTSD? … AE = adverse events; CBT = cognitive behavioral therapy; DSM = Diagnostic and Statistical Manual; EFT … Impact of Events Scale - Revised (IES-R). … caused by traumatic
events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
September 01, 2011 - Specifically, the reported adverse event
experience with TMS is now very well established in the two … events observed in TMS
George, et al, (2010) was included during the
update search phase post submission … (2000) The effects of
electroconvulsive therapy in memory of autobiographical and public
events. … events, and therefore lacks the toxicities of more
complex antidepressant pharmacotherapies or the … events responded better to the form of CBT tested than
to any drug intervention.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-endocrine-therapy_research.pdf
August 01, 2012 - and tamoxifen find that up to one-third
of women discontinue use within three years of starting.7 Adverse … Both drugs seem to have similar
adherence problems despite distinct
adverse effect profiles.7,8 Prior
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
December 09, 2009 - events, or adherence? … Adverse effects of interest include but are not limited
to: amnesia, memory loss, headaches, post-operative … : ECT, rTMS, VNS, demonstrated effective psychotherapy
• Outcomes for each question
• Safety
• Adverse … Events
• Adherence
• Timing: Acute phase and continuation phase treatments
• Settings: Mental … KQ4 focuses on safety issues (adverse effects, adherence) with
each of the interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - Adverse Event Detection,
Processing, and Reporting
The U.S. … Food and Drug Administration defines an
adverse event (AE) as any untoward medical
occurrence in a patient … reporting for all marketed
products is dependent on the principle of “becoming
aware,” collection of adverse … • The process for identifying serious events is described and a plan is created for reporting, as … • For safety studies, personnel are appropriately trained to ask about complaints or adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
January 01, 2012 - care or other interventions without SMBP in its
effect on relevant clinical outcomes (cardiovascular
events … , mortality, patient satisfaction, quality of
life, and adverse events related to antihypertensive … Note: AE = adverse event; BP = blood pressure; CVD = cardiovascular disease; KQ = Key Question; LVH = … ,
mortality, patient satisfaction, quality of life, and
adverse events related to antihypertensive … One quality C trial found no
difference in adverse drug reactions across four groups with different
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
January 01, 2014 - What are the adverse effects associated with each diagnostic test (including pain,
infection at the … events: immediate
• Settings:
o Primary care (outpatient) or acute care setting, preferentially … events (including adverse patient experiences such as pain or
infection at the aspiration site, effects … events will be included
for key question 2, in anticipation that few studies will address the question … of adverse
outcomes or patient satisfaction with diagnostic procedures.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_surveillance.pdf
October 01, 2012 - children
increases the risk for obesity
and any cardiovascular,
cerebrovascular, or
hypertensive adverse … January 2012 -
Conclusion still valid; as
strength of evidence for
adverse effects was rated
as high … We rated the strength of
evidence as high for the
adverse effects of both
medications, moderate
for … January 2012 -
Conclusion still valid; as
strength of evidence for
adverse effects was rated
as high … We rated the strength of evidence as high
for the adverse effects of both medications,
moderate for
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-228-nonopioid-pharm-chronic-pain-comments.pdf
April 16, 2020 - including
information on potential harms of treatment as well as information on
withdrawals due to adverse … events.
-
effectivehealthcare.ahrq.gov/products/ambulatory-safety/technical-brief
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
November 01, 2007 - The major randomized clinical trials proving the favorable effect of β-blockers on
adverse outcomes … variables previously reported to be associated with either receipt of heart failure therapies or
adverse … events in patients who have heart
failure with or without diabetes.(25) Chronic lung disease with a … Gender
and risk of adverse outcomes in heart failure. Am
J Cardiol 2004;94(9):1147-52.
24. … Chronic
kidney disease and the risks of death,
cardiovascular events, and hospitalization.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression_hi_impact.pdf
October 01, 2014 - Ketamine was generally well-tolerated; the most common adverse effect was dissociative symptoms,
only … There were no drug-related serious adverse events, adverse neurocognitive
effects or clinically significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
November 12, 2013 - in the extraction
forms for Key Questions related to intermediate outcomes, terminal outcomes, or adverse … events, and for factors affecting (modifying) the treatment effect among subgroups of
patients, as … reporting (separately for each outcome of
interest), number of enrolled patients, and numbers of observed events