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Showing results for "adverse events".
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101. CER 220 Evidence Summary: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
     September 01, 2019 - The intranasal route was common in studies reporting adverse events for the comparison of opioids versus … Opioids may cause fewer adverse events than ketamine, primarily administered IN. … Opioids may cause more adverse events than NSAIDs, administered primarily IV. … evidence suggests that opioids may cause fewer total adverse events than ketamine. … In contrast to the comparison of opioids with ketamine, opioids may cause more adverse events than

102. AHRQ Evidence-Based Practice Center (EPC) Program Research Gaps Summary: Pain Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
     January 01, 2023 - Serious adverse events are more common in patients who received lasmiditan than placebo. … Evidence is insufficient to draw conclusions about serious adverse events. … Evidence is insufficient to draw conclusions about serious adverse events. … events, nausea, dizziness, and somnolence, but serious adverse events are uncommon in randomized trials … Large increases in withdrawal due to adverse events were seen with oxcarbazepine.

103. Microsoft Word - Comp Eff 10.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
     January 01, 2007 - d Safety outcomes considered were overall adverse events, withdrawals due to adverse events, serious … d Safety outcomes: Overall adverse events, withdrawals due to adverse events, serious adverse events … due to adverse events) … Safety and Adverse Events Rates of serious and overall adverse events Seven studies met our inclusion … events related to the nervous system, adverse events related to the cardiovascular system, and adverse

104. Adverse Effects of First-line Pharmacologic Treatments of Major Depression in Older Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/depression-harms/research-protocol
     February 07, 2018 - selecting therapy based on comparative adverse effects. … Outcomes: We are interested in the following adverse effects for KQ1 and KQ2: Any adverse event, as … in those who experienced an adverse events Withdrawal due to adverse events Serious adverse events … The critical outcomes include suicide, mortality, hospitalization, serious adverse events, arrhythmias … Meta-analysis of rare binary events in treatment groups with unequal variability.

105. Nonopioid Pharmacologic Treatments for Chronic Pain: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
     April 01, 2020 - • Small to moderate, dose-dependent increases in withdrawal due to adverse events were found with … Harms and adverse events: – What are the risks of nonopioid pharmacologic agents for harms including … overdose, misuse, dependence, withdrawals due to adverse events, and serious adverse events, and … specific adverse events? … Other adverse events of interest were not reported (cognitive effects, misuse, addiction, substance

106. Comparative Effectiveness Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
     January 01, 2006 - COX-2s vs NSAIDs - tolerability Trial Withdrawals due to adverse events Total adverse events … COX-2s vs NSAIDs - tolerability Trial Withdrawals due to adverse events Total adverse events … COX-2s vs NSAIDs - tolerability Trial Withdrawals due to adverse events Total adverse events … Adverse Effects Reported Total withdrawals; withdrawals due to adverse events Tugwell 2004 Not … due to adverse events Appendix F.

107. Management of Primary Headache During Pregnancy | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/headaches-pregnancy/protocol
     November 12, 2019 - Adverse events: Maternal: Serious maternal adverse events:* "Serious" adverse events (including those … /infant: Serious fetal/infant adverse events:* "Serious" adverse events (including those that are composite … Adverse events: Maternal: Serious maternal adverse events:* "Serious" adverse events (including those … /infant: Serious fetal/infant adverse events:* "Serious" adverse events (including those that are composite … ) due to neonatal/infant adverse events.

108. Management of Primary Headache During Pregnancy: Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
     March 23, 2019 - events o Maternal  Serious maternal adverse events* • “Serious” adverse events (including those … events* o Fetal/infant  Serious fetal/infant adverse events* • “Serious” adverse events (including … events o Maternal  Serious maternal adverse events* • “Serious” adverse events (including those … events* o Fetal/infant  Serious fetal/infant adverse events* • “Serious” adverse events (including … ) due to neonatal/infant adverse events.

109. Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
     May 01, 2016 - systematic review evaluating the evidence regarding the effectiveness, comparative effectiveness, and adverse … Topiramate also increased binge-eating abstinence. �� Adverse effects of BED treatments were mainly … Table 2: Summary of Key Findings for Adverse Effects of Pharmacological Interventions Intervention and … Comparator N RCTs N Subjects N Reported Events (Intervention vs. … events, serious adverse events, and study discontinuations clearly attributable to adverse events,

110. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
     September 01, 2009 - Long-Term Benefits and Serious Adverse Events There are several important limitations in the evidence … Absolute rates of serious adverse events varied between 2 and 4 percent. … Early withdrawal due to adverse events was more likely for the combination of statin plus niacin than … However, three of six trials showed significantly more participants experiencing adverse events with … Long-Term Benefits and Serious Adverse Events • The comparator for trials of combination therapy in

111. Noninvasive Treatments for Low Back Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
     February 01, 2016 - placebo: Adverse events Low A systematic review found that central nervous system adverse events such … placebo: Adverse events, serious adverse events Moderate Antidepressants were associated with higher … in risk of adverse events. … Yoga: Adverse events Low Reporting of harms was suboptimal, but adverse events, when reported, were … No serious adverse events were reported, and most adverse events were related to muscle soreness or

112. Cannabis-App-F5-Table-Surveillance-Report-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2.xlsx
     January 22, 2022 - Events Other Reported Outcomes Funding Source Risk of Bias 21087411 Bestard, 2011 Prospective cohort … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. … NR Serious adverse events: none in any group Withdrawals due to adverse events 6 months: 10% (5/49) vs … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04) Withdrawals due to adverse … events: 4.65% (10/215) vs.

113. Appendix-E-Table-E5 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5.xlsx
     November 04, 2021 - Events Other Reported Outcomes Funding Source Risk of Bias 21087411 Bestard, 2011 Prospective cohort … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. … NR Serious adverse events: none in any group Withdrawals due to adverse events 6 months: 10% (5/49) vs … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04) Withdrawals due to adverse … events: 4.65% (10/215) vs.

114. Cannabis-App-F5-Table-Surveillance-Report-2 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0.xlsx
     February 16, 2022 - Events Other Reported Outcomes Funding Source Risk of Bias 21087411 Bestard, 2011 Prospective cohort … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. … NR Serious adverse events: none in any group Withdrawals due to adverse events 6 months: 10% (5/49) vs … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04) Withdrawals due to adverse … events: 4.65% (10/215) vs.

115. Cannabis-App-F5-Table-Surveillance-Report-2 0 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-f5-table-surveillance-report-2_0_0.xlsx
     February 16, 2022 - Events Other Reported Outcomes Funding Source Risk of Bias 21087411 Bestard, 2011 Prospective cohort … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. … NR Serious adverse events: none in any group Withdrawals due to adverse events 6 months: 10% (5/49) vs … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04) Withdrawals due to adverse … events: 4.65% (10/215) vs.

116. Appendix-E-Table-E5 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix-E-Table-E5_0.xlsx
     November 04, 2021 - Events Other Reported Outcomes Funding Source Risk of Bias 21087411 Bestard, 2011 Prospective cohort … C % (n/N) Any adverse event 3 months: 35% (19/49) vs. 47% (30/52) vs. … NR Serious adverse events: none in any group Withdrawals due to adverse events 6 months: 10% (5/49) vs … adverse events: 13% (28/215) vs. 19.4% (42/216), OR 0.64 (95% CI 0.38 to 1.04) Withdrawals due to adverse … events: 4.65% (10/215) vs.

117. Medicare Prescription Drug Data Development: Methods for Improving Patient Safety and Pharmacovigilance Using Observational Data | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/patient-safety-databases-prescriptions/research
     August 26, 2008 - events than leave placebo groups (18 percent). 19 Evidence suggests that the total of adverse events … Rates of adverse events differ widely across trials and drugs. … Adverse Drug Events Outcomes associated with adverse drug events. … Idiosyncratic adverse events. … This markedly limited our power to detect rare adverse events.

118. Psoriatic Arthritis Surveillance Assesment_CER 54_Low (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
     March 01, 2013 - (INSUFFICIENT) Biologic: Etanercept had a lower rate of withdrawals because of adverse events than … (SIEs) were the most frequently reported serious adverse events. … Common adverse events include: nausea/ vomiting, respiratory infection, abdominal pain, abnormal … ACR50 response rates were Did not conduct statistical tests on adverse events data. … (SIEs) were the most frequently reported serious adverse events.

119. Executive Summary for CER No. 258_Diagnostic Errors in the Emergency Department: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-258-diagnostic-errors-summary.pdf
     December 01, 2022 - Some of these patients suffer an adverse event because of the incorrect diagnosis (~2.0%), and some of … these adverse events are serious (~0.3%). … events, and 75 serious harms, including 50 deaths per ED. … events with preventable harms; and 371,000 (PR 142,000 to 909,000) serious misdiagnosis-related harms … Serious misdiagnosis-related harms in malpractice claims: The “Big Three” – vascular events, infections

120. Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
     October 01, 2021 - events in randomized trials, Dr. … The dot plot also shows the number of adverse events in each group. … For dichotomous outcomes, the dot plots show for each outcome the pooled absolute rate of events in … events, cancer, diabetes, myalgia, and liver enzyme abnormalities. … events, serious adverse events, nausea, vomiting, constipation, somnolence, dizziness, and pruritus